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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Blood Cells and Redox Homeostasis in Health and Disease, 2nd Edition

edited by

Angelo D'Alessandro

and

Alkmini T. Anastasiadi

submission deadline 30 Mar 2026 | 5 articles | Viewed by 5787 | Submission Open

Keywords: blood; redox status; antioxidants; oxidative stress; redox therapy; oxidative stress biomarkers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

New Insight into Redox Homeostasis and Oxidative Stress in Health and Disease: Focus on Cardiac and Vascular Function

edited by

István Szokodi

and

Endre Sulyok

submission deadline 30 Mar 2026 | 2 articles | Viewed by 2402 | Submission Open

Keywords: reactive oxygen/nitrogen species; oxidative/nitrosative stress; redox signaling; atherosclerosis; hypertension; stroke; myocardial infarction; heart failure; biomarker; translational and precision medicine

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Heme Proteins and Signaling in Redox Biology

edited by

Brandon Reeder

submission deadline 30 Mar 2026 | Viewed by 92 | Submission Open

Keywords: heme proteins; redox biology; globin; oxygen binding and sensing proteins

(This special issue belongs to the Section ROS, RNS and RSS)

Oxidative Stress and Its Mitigation in Neurodegenerative Disorders

edited by

D. Allan Butterfield

submission deadline 31 Mar 2026 | 3 articles | Viewed by 3984 | Submission Open

Keywords: oxidative stress; neurodegenerative disorders; brain; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Metabolic Disorders and Non-Communicable Diseases (NCDs): Molecular Pathways and Genetic Influence

edited by

Roberta Giordo

submission deadline 31 Mar 2026 | 2 articles | Viewed by 3133 | Submission Open

Keywords: metabolic disorders; non-communicable diseases (NCDs); reactive oxygen species (ROS); genetic influence; molecular pathways

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Cardiovascular Diseases and Vascular Pathophysiology

edited by

Guillermo Zalba

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2829 | Submission Open

Keywords: atherosclerosis; diabetes; heart failure; inflammation; myocardial infarction; NADPH oxidase; oxidative stress; reactive oxygen species; stroke

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Recent Trends in Nanoantioxidants—2nd Edition

edited by

Maria Letizia Manca

and

Matteo Perra

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1872 | Submission Open

Keywords: nanocarriers; liposomes; nanocrystals; oxidative stress; inflammation; antioxidant; cosmeceuticals; nutraceuticals; ROS; liposomes; nanosystems

Role of Antioxidants and Oxidative Stress in Neurodegenerative Diseases

edited by

Barbara Sottero

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1804 | Submission Open

Keywords: neurodegenerative diseases; antioxidants; oxidative stress; Parkinson’ s disease; Alzheimer’ s disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Microalgae FoodOmics and FeedOmics: Antioxidant Enrichment, ROS Modulation, and Health-Boosting Applications

edited by

Clementina Sansone

and

Francesca Sansone

submission deadline 31 Mar 2026 | Viewed by 913 | Submission Open

Keywords: microalgae; bioactive compounds; antioxidants; antioxidant metabolism; antioxidant biosynthesis; omics; vitamins; probiotics; prebiotics; postbiotics; drug delivery; signal transduction; gut/brain axis

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Small Molecule Approaches to Modulating Oxidative Stress Responses

edited by

Hidekazu Hiroaki

submission deadline 31 Mar 2026 | Viewed by 765 | Submission Open

Keywords: natural products; nutraceuticals; antioxidants; polyphenols; flavonoids; barrier function; cellular senescence; inflammation; DNA damage; regeneration

Food Proteins and Peptides as Antioxidants: Resource, Extraction, Functional Property and Application

edited by

, Di Li and

submission deadline 31 Mar 2026 | 1 articles | Viewed by 582 | Submission Open

Keywords: protein resources; protein extraction and characterization; functional properties of proteins; antioxidant activity; protein application

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Impact of Antioxidant and Anti-Inflammatory Functions of HDL in Diseases—3rd Edition

edited by

Carlo Cervellati

and

Judit Marsillach

submission deadline 31 Mar 2026 | Viewed by 233 | Submission Open

Keywords: paraoxonases; oxidized LDL; high-density lipoproteins; metabolic diseases; apolipoproteins; cardiovascular disease; neurological disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Therapies, Mitochondrial Function, and Transplantation Strategies: Mechanisms and Emerging Therapeutics

edited by

Junhwan Kim

and

P. Singh

submission deadline 31 Mar 2026 | Viewed by 201 | Submission Open

Keywords: oxidative stress; antioxidant therapies; mitochondrial function; mitochondrial dysfunction

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Peroxiredoxins

edited by

Dong-Seok Lee

submission deadline 31 Mar 2026 | Viewed by 195 | Submission Open

Keywords: peroxiredoxins; oxidative stress; neuron; neuroinflammation; stemness; cancer

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Optimizing Physical Exercise: Post-Exercise Recovery, Oxidative and Nitrosative Stress, and the Role of Physical Activity in Healthy Aging and Neuroprotection

edited by

Celestyna Mila-Kierzenkowska

and

Marta Pawlowska

submission deadline 31 Mar 2026 | Viewed by 173 | Submission Open

Keywords: oxidative stress; exercise; nitrosative stress; post-exercise damage; post-exercise regeneration; aging; neuroprotection

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Therapeutic Potential of Natural Antioxidants in Respiratory Diseases and Airway Inflammation

edited by Yo-Han Han

submission deadline 31 Mar 2026 | Viewed by 130 | Submission Open

Keywords: natural product; acute/chronic lung injury; inflammation; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Redox Signaling in Kidney Diseases

edited by Xiaofeng Yang

submission deadline 31 Mar 2026 | Viewed by 78 | Submission Open

Keywords: oxidative stress; redox signaling; kidney diseases; antioxidant defense; inflammation; biomarkers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Dietary Antioxidants, Oxidative Stress, and Women’s Reproductive Health

edited by

Miran Čoklo

submission deadline 31 Mar 2026 | Viewed by 74 | Submission Open

Keywords: oxidative stress; women’ s reproductive health; dietary antioxidants; female fertility; reproductive outcomes; polycystic ovary syndrome (PCOS); endometriosis; preeclampsia; nutritional interventions; bioactive compounds; lifestyle modifications

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox-Based Targeting of Signaling Pathways as a Therapeutic Approach

edited by

Seung-rock Lee

and Dhiraj Kumar Sah

submission deadline 31 Mar 2026 | Viewed by 70 | Submission Open

Keywords: cellular signaling; redox-based; therapeutic intervention; human disease; longevity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Antioxidants in Carcinogenesis: A Multifaceted Approach—2nd Edition

edited by

Fábio Rodrigues Ferreira Seiva

submission deadline 31 Mar 2026 | Viewed by 60 | Submission Open

Keywords: oxidative stress; carcinogenesis; reactive oxygen species (ROS); antioxidants; cancer therapeutics

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Roles of Oxidative Stress in Human Pathophysiology

edited by

Alexandros Georgakilas

submission deadline 31 Mar 2026 | Viewed by 59 | Submission Open

Keywords: oxidative stress; reactive oxygen species; redox signaling; antioxidants; inflammation; biomarkers; human diseases; therapy; pathology; pathophysiology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Inflammation in Kidney Diseases

edited by

Andrea Angeletti

submission deadline 31 Mar 2026 | Viewed by 54 | Submission Open

Keywords: chronic renal failure; clinical nephrology; renal physiology; glomerulonephritis; diabetic nephropathy; renal disease; oxidative stress; kidney transplantation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Food Matrices: From Analytical Advances to Circular and Sustainable Applications

edited by

Sara Jaramillo-Carmona

and

Rafael Guillén Bejarano

submission deadline 31 Mar 2026 | Viewed by 51 | Submission Open

Keywords: food matrix; bioaccesibility; bioavailability; functionality; by-products; valorization; circular economy

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Biological Activities of Antioxidant Selenoproteins

edited by

Raquel Martin-Venegas

submission deadline 31 Mar 2026 | Viewed by 42 | Submission Open

Keywords: selenoproteins; selenium metabolism; microbial redox regulation; bacteria– host redox interactions; oxidative stress; antioxidant defence

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Capacity of Natural Products—3rd Edition

edited by

Younghwa Kim

submission deadline 31 Mar 2026 | Viewed by 34 | Submission Open

Keywords: natural antioxidants; oxidative stress; phytochemicals; bioactive compounds; reactive oxygen species (ROS)

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Natural Antioxidants from Agro-Wastes and Food Waste: Characterization and Applications

edited by

Charles Manful

and Raymond H. Thomas

submission deadline 31 Mar 2026 | Viewed by 7 | Submission Open

Keywords: natural antioxidants; oxidative stress; carotenoids; terpenes; phytochemicals; polyphenols; functional foods; bioavailability; translational research; chronic diseases; optimization

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Antioxidant Defenses and Retinal Inflammation in Diabetic Retinopathy

edited by Devy Deliyanti

submission deadline 31 Mar 2026 | Viewed by 1 | Submission Open

Keywords: retinal injury; diabetic retinopathy; retinal inflammation; cell death; antioxidant; pro-oxidants; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant and Antidiabetic Activities of Plant Matrices: Methods, Mechanisms, and Translational Relevance

edited by

Sabina Lachowicz-Wiśniewska

submission deadline 31 Mar 2026 | Submission Open

Keywords: antioxidant assays; antidiabetic activity; α -glucosidase; α -amylase; DPP-IV; antiglycation/AGEs; tea (Camellia sinensis); wild plants; neglected and underutilized species (NUS); stachys; root and tuber crops; ultrasound; microwave; bioavailability; metabolomics; layer-by-layer; hydrogels; alginate; pectin; chitosan; zein; processing by-products

Reactive Nitrogen Species (RNS) and Redox Signaling in Tumors

edited by Maria Clara Franco and

Luciana Hannibal

submission deadline 10 Apr 2026 | 1 articles | Viewed by 5886 | Submission Open

Keywords: tumor biology; reactive nitrogen species; redox signaling; oxidative stress; ROS

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Biology of Glyoxalases and Advanced Glycation End Products in Health and Diseases

edited by

Cinzia Antognelli

Marilena Pariano

and

Vincenzo Nicola Talesa

submission deadline 10 Apr 2026 | 6 articles | Viewed by 3763 | Submission Open

Keywords: glyoxalases; methylglyoxal; advanced glycation end products; aging; diseases; antioxidants; apoptosis; cell proliferation; nutraceuticals; oxidative stress; inflammation; apoptosis; EMT; cell proliferation; signal transduction; biological mechanisms

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Natural Antioxidants for Cosmetic Applications

edited by

Rita Cortesi

and

Maddalena Sguizzato

submission deadline 10 Apr 2026 | Viewed by 94 | Submission Open

Keywords: cosmetic formulations; skin care; oxidative stress; photoprotection

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants and Metabolic Diseases, 2nd Edition

edited by

José Ángel Rufián-Henares

Fortuna Iannuzzo

Elisabetta Schiano

and

Maria Maisto

submission deadline 10 Apr 2026 | Viewed by 56 | Submission Open

Keywords: metabolic syndrome; antioxidant compounds; diabetes; obesity; cardiovascular diseases; biological effects; food sources; medicinal plants; oxidative stress; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Synthetic Compounds: Antioxidant and Anti-Inflammatory Activities, Biomedical Properties and Formulations

edited by

Simone Carradori

and

Ilaria D'Agostino

submission deadline 20 Apr 2026 | 3 articles | Viewed by 5667 | Submission Open

Keywords: antioxidants; inflammation pathways; therapeutic activity; redox potential; synthesis; preclinical studies; macrophages; immunomodulation; packaging; formulations; topical application; polymers; nanotechnology; cytotoxicity; mechanism of action; food; drug design

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress, Mitochondrial Dysfunction, and Inflammation in Autism

edited by

Abha Chauhan

submission deadline 20 Apr 2026 | Viewed by 168 | Submission Open

Keywords: autism; oxidative stress; mitochondria; inflammation; redox signaling; antioxidants; reactive oxygen species; immune response

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Targeting Oxidative Stress in Ischemia/Reperfusion Injury

edited by Kenneth J. Dery

submission deadline 20 Apr 2026 | Viewed by 81 | Submission Open

Keywords: ischemia/reperfusion injury; reactive oxygen species; redox-regulated molecular and cellular mechanism; antioxidant-based therapeutic strategies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Striated Muscle and Other Tissues

edited by

Enrique Jaimovich

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2214 | Submission Open

Keywords: ROS/RNS production; mitochondria ROS; NADPH oxidase; metabolic regulation; cardiac oxidative stress; ROS sources; exercise-induced ROS/RNS; antioxidants; ROS/RNS in disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Resilience Signaling of Functional Nutrients and Neurotoxicant Pollutants for Human Health

edited by

Maria Scuto

and

Angela Trovato Salinaro

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1615 | Submission Open

Keywords: dietary nutrients; polyphenol-basaed nanoparticles; oxidative stress; apoptosis; ferroptosis; pyroptosis; hormesis; inflammation; human health; toxicant pollutants; apoptosis; cancer; nervous system disorders; personalized nutritional therapy

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

High-Fat Diet-Induced Oxidative Stress

edited by

María Teresa Llinas Más

and

Isabel Hernández

submission deadline 30 Apr 2026 | 1 articles | Viewed by 695 | Submission Open

Keywords: saturated fats; fats; high-fat diet; obesity; cardiovascular disease; non-alcoholic fatty liver disease; oxidative stress; antioxidants; cancer; neurodegenerative diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Nrf2 and Cardiovascular Function, Diseases, and Therapeutic Targets

edited by

Gao Lie

and

Irving H. Zucker

submission deadline 30 Apr 2026 | Viewed by 494 | Submission Open

Keywords: nuclear factor erythroid 2-related factor 2 (Nrf2); Nrf2-targeted therapies; cardiovascular diseases; antioxidant; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Hearing Loss—2nd Edition

edited by Lei Song and Joseph Santos-Sacchi

submission deadline 30 Apr 2026 | Viewed by 106 | Submission Open

Keywords: ear; outer hair cell; inner ear

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Phytotherapy and Natural Products in the Treatment and Prevention of Chronic Diseases

edited by

Sara Damiano

and

Roberto Ciarcia

submission deadline 30 Apr 2026 | Viewed by 44 | Submission Open

Keywords: chronic diseases; phytotherapy; natural antioxidants; plant-derived compounds

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Based on Antioxidant Capacity: The Multifunctional Roles of Bioactive Compounds from Fruits and Vegetables in Precision Nutrition

edited by

Mauro Lombardo

submission deadline 30 Apr 2026 | Viewed by 27 | Submission Open

Keywords: fruits and vegetables; antioxidants; anti-inflammatory; plant compounds; health

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants Isolation and Characterization

edited by José Luis Todolí Torró and

Ana Beltrán Sanahuja

submission deadline 30 Apr 2026 | Viewed by 26 | Submission Open

Keywords: plant-derived antioxidants; polyphenols; flavonoids; carotenoids; phenolic acids; green extraction techniques; chromatographic and spectroscopic analysis; metabolomics; antioxidant activity evaluation; agro-industrial by-products valorization

(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)

Molecular Crosstalk Between Redox Signaling and Intestinal Health: The Role of Dietary Antioxidants

edited by

Carla Gentile

and Graziella Serio

submission deadline 30 Apr 2026 | Viewed by 21 | Submission Open

Keywords: redox signaling; intestinal inflammation; dietary antioxidants; NF-κ B signaling; Nrf2 signaling; epigenetic regulation; tight junctions; polyphenols; melatonin; phytomelatonin

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Livestock and Poultry—3rd Edition

edited by

Wutai Guan

and

Shihai Zhang

submission deadline 30 May 2026 | 5 articles | Viewed by 5660 | Submission Open

Keywords: oxidative stress; environmental stressors; gut microbiome; antioxidant strategies; epigenetic modifications

Innovative Analytical Pathways: Exploring Phytochemical Profiles and Bioactivities Through Advanced Instrumentation

edited by

Igor Piotr Turkiewicz

and

Karolina Tkacz

submission deadline 30 May 2026 | 1 articles | Viewed by 940 | Submission Open

Keywords: phytochemical profiling; bioactivity analysis; pharmacodynamics and pharmacokinetics of antioxidants; advanced instrumentation; natural antioxidants; extraction and isolation techniques; structural characterization; industrial applications of antioxidants; LC-MS; GC-MS; HRMS; NMR; FTIR

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

The OxInflammation Process and Tissue Repair

edited by Reggiani Vilela Gonçalves, Mariaurea Matias Sarandy and Rômulo Dias Novaes

submission deadline 31 May 2026 | 5 articles | Viewed by 14618 | Submission Open

Keywords: oxidative stress; inflammasome; cytokines; angiogenesis; molecular biology; cellular and molecular mechanisms; diabetes; tissue repair

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress Mechanisms and Parkinson's Disease Treatment

edited by

Juan Segura-Aguilar

submission deadline 31 May 2026 | 1 articles | Viewed by 1785 | Submission Open

Keywords: Parkinson’ s disease; dopamine; dopamine oxidation; neuromelanin; dopaminergic neurons; antioxidants; neuroprotection; neurodegeneration; oxidative stress; protein degradation dysfunction; neuroinflammation; mitochondrial dysfunction; endoplasmic reticulum stress; alpha-synuclein oligomers; glutathione; glutathione transferase; DT-diaphorase; preclinical model for Parkinson's disease; VMAT2; dopamine transporter; tyrosine hydroxylase; dopamine-derived orto-quinones

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant and Antimicrobial Activity of Honey Bee Products—3rd Edition

edited by

Ivana Tlak Gajger

and

Josipa Vlainić

submission deadline 31 May 2026 | Viewed by 78 | Submission Open

Keywords: honey bee products; antioxidant capacity; antimicrobial efficacy; polyphenol content; functional food; health promotion

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Antioxidant Peptides from Marine Organisms: Structural Insights, Functional Mechanisms, and Sustainable Applications

edited by Changfeng Chi

submission deadline 1 Jun 2026 | 1 articles | Viewed by 132 | Submission Open

Keywords: marine peptides; antioxidant activity; structure identification; structural modification; bioactivity and function; structure; function relationship; functional foods; biodiversity; organismic diversity and diversity preservation; genetic diversity

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