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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gallbladder, Bile Duct and Pancreas Disorders: Current Challenges, New Perspectives and Innovative Techniques

edited by

Daniel Paramythiotis

Robert Grützmann

, Vasileios Papaziogas, Dimitrios Raptis and

Eleni Karlafti

submission deadline 20 Dec 2025 | 7 articles | Viewed by 30298 | Submission Open

Keywords: pancreas; biliary tract; pancreatobiliary diseases; pancreas neoplasm; tumor; ERCP; EUS; management; therapy; technique; surgery

(This special issue belongs to the Section Gastroenterology & Hepatology)

Precision Medicine Approach in Septic Patients

edited by

Gabriela Droc

and

Sebastian Isac

submission deadline 20 Dec 2025 | 1 articles | Viewed by 5008 | Submission Open

Keywords: sepsis; septic shock; precision medicine; epigenomics; cytomics; genomics; proteomics; metabolomics; transcriptomics

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Advances in Bypass Surgery in Cardiology

edited by

Giuseppe Nasso

and

Ignazio Condello

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4923 | Submission Open

Keywords: Coronary Artery Bypass Grafting (CABG); minimally invasive cardiac surgery; cardiopulmonary bypass; hybrid coronary revascularization; off-pump surgery; myocardial protection; surgical outcomes in cardiology

(This special issue belongs to the Section Cardiology)

Advances in Cervical Cancer Treatment and HPV Management: From Conventional Therapies to Emerging Strategies

edited by Mariano Catello Di Donna and Maria Cristina Solazzo

submission deadline 20 Dec 2025 | 1 articles | Viewed by 3563 | Submission Open

Keywords: cervical cancer; HPV; immunotherapy; targeted therapies; personalized medicine; radical hysterectomy; fertility-sparing surgery; multimodal treatment

(This special issue belongs to the Section Obstetrics and Gynecology)

Current Advances in Diagnosis and Surgical Treatment of the Head and Neck Disorders, 2nd Edition

edited by Poramate Pitak-Arnnop and

Christian Stoll

submission deadline 20 Dec 2025 | 1 articles | Viewed by 3389 | Submission Open

Keywords: head and neck injury; head and neck trauma; head and neck cancer; oncology; head and neck infection; congenital orofacial deformity; orofacial pain; facial plastic and reconstructive surgery; facial aesthetic medicine; head and neck reconstruction

(This special issue belongs to the Section Surgery)

Diagnosis and Treatment of Obstructive Sleep Apnea

edited by Goran Račić, Željka Roje and Zlatko Kljajic

submission deadline 20 Dec 2025 | Viewed by 197 | Submission Open

Keywords: obstructive sleep apnea; polysomnography; obstructive sleep apnea diagnosis; obstructive sleep apnea treatment; obstructive sleep apnea etiology; obstructive sleep apnea complications; adult OSA; pediatric OSA

(This special issue belongs to the Section Pulmonology)

Diagnosis and Treatment of Cervical Cancer: Second Edition

edited by

Tullio Golia D’Augè

and Giorgia Perniola

submission deadline 25 Dec 2025 | 1 articles | Viewed by 1608 | Submission Open

Keywords: cervical cancer; radical hysterectomy; prevention; cervical intraepithelial neoplasia; cervical cancer screening; early diagnosis

(This special issue belongs to the Section Obstetrics and Gynecology)

Update on B-Cell Leukemias and Lymphomas

edited by

Diana Cenariu

and

Adrian-Bogdan Țigu

submission deadline 25 Dec 2025 | 1 articles | Viewed by 1519 | Submission Open

Keywords: biomarkers for diagnosis; genetic mutations; epigenetic regulation; niche interaction; immunotherapy; targeted therapy; CAR T-cell therapy

(This special issue belongs to the Section Hematology and Immunology)

Recent Advances in Gynecological Surgery

edited by

Felice Sorrentino

submission deadline 30 Dec 2025 | 4 articles | Viewed by 6434 | Submission Open

Keywords: hysteroscopy; laparoscopy; robotics; vNOTES; laser; gynecological surgery; resectoscope

(This special issue belongs to the Section Obstetrics and Gynecology)

Psychiatric Comorbidities and Substance Use Among Individuals with Physical Health Issues and Chronic Diseases

edited by

Jagdish Khubchandani

submission deadline 30 Dec 2025 | Viewed by 234 | Submission Open

Keywords: psychiatry; substance use; chronic disease; physical health issues; addiction; mental health; health outcomes; alcohol; tobacco; and other drug use; healthcare utilization

Advances in Soft and Hard Tissue Management Around Dental Implants

edited by

Roberto Rossi

and

Fabrizio Bambini

submission deadline 31 Dec 2025 | 10 articles | Viewed by 26172 | Submission Open

Keywords: dental implants; soft tissue around implants; bone regeneration; prosthetic implants; esthetic implants

(This special issue belongs to the Section Dentistry and Oral Health)

Clinical Applications of Modern Technologies in Neurosurgery and Spine Surgery

edited by

Mirza Pojskić

Christopher Nimsky

and

Miriam H. A. Bopp

submission deadline 31 Dec 2025 | 8 articles | Viewed by 24582 | Submission Open

Keywords: modern technologies; neuronavigation; augmented reality; virtual reality; robotics; endoscopy; tumor treating fields; tumor biology; intraoperative ultrasound; intraoperative computed tomography; intraoperative magnetic resonance imaging; neuroradiology; neurosurgery; spine surgery

(This special issue belongs to the Section Neurology)

Physical Therapy: A New Perspective

edited by

Manuel González-Sánchez

and Laura Zlibinaite

submission deadline 31 Dec 2025 | 6 articles | Viewed by 17329 | Submission Open

Keywords: physical therapy; physiotherapy; therapeutic exercise; rehabilitation; exercise prescription; treatment techniques; musculoskeletal health; movement impairments; functional abilities; innovation

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Chronic Inflammatory Skin Diseases: Where We Are and Where We Are Going: 2nd Edition

edited by

Fabrizio Martora

and

Matteo Megna

submission deadline 31 Dec 2025 | 6 articles | Viewed by 16253 | Submission Open

Keywords: psoriasis; atopic dermatitis; hidradenitis suppurativa; skin inflammatory disease

(This special issue belongs to the Section Dermatology)

Early Diagnosis and Management of Glioma

edited by Maurizio Iacoangeli and

Denis Aiudi

submission deadline 31 Dec 2025 | 5 articles | Viewed by 9372 | Submission Open

Keywords: glioma; glioblastoma; neuroimaging; neuro-oncology; early diagnosis; modern technologies; neurosurgery; tumor biology; early therapy; new therapies

(This special issue belongs to the Section Oncology)

New Insights into Plastic and Reconstructive Surgery

edited by

Francesco De Francesco

and Michele Riccio

submission deadline 31 Dec 2025 | 5 articles | Viewed by 8062 | Submission Open

Keywords: microsurgery; regenerative medicine; tissue engineering; robotic surgery; biomimetic materials; aesthetic surgery; wound healing; 3D printing; reconstructive techniques; psychological impacts

(This special issue belongs to the Section Surgery)

Diabetes and Obesity: What Is New in 2025

edited by

Manfredi Rizzo

and

Ali Abbas Rizvi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 7174 | Submission Open

Keywords: diabetes; obesity; metabolic syndrome; cardiovascular disease; insulin resistance

(This special issue belongs to the Section Endocrinology)

Diagnosis and Treatment of Urologic Oncology

edited by

Juan Gómez Rivas

and Jesús Moreno Sierra

submission deadline 31 Dec 2025 | 5 articles | Viewed by 5831 | Submission Open

Keywords: bladder cancer; kidney cancer; personalized medicine; prostate cancer; robotic surgery; targeted therapy; testicular cancer

(This special issue belongs to the Section Urology & Nephrology)

Updates on Oral Surgery

edited by

Mario Caggiano

and

Alfonso Acerra

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2638 | Submission Open

Keywords: oral surgery; digital technology; minimally invasive techniques; biomaterials; regenerative medicine; 3D printing; artificial intelligence; surgical navigation; robotics

(This special issue belongs to the Section Dentistry and Oral Health)

Prophylaxis, Diagnosis, and Treatment Strategies of Gastric Cancer

edited by Nadim Al Hajjar and Andra Ciocan

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2214 | Submission Open

Keywords: gastric cancer; treatment; prevention; diagnosis; surveillance; follow-up; neoadjuvant therapy; prognosis; biomarkers

(This special issue belongs to the Section Oncology)

Orthopedic Trauma: Surgical Treatment and Rehabilitation

edited by Yong Girl Rhee and Myung-seo Kim

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2017 | Submission Open

Keywords: orthopedic trauma; shoulder and elbow; knee; foot; and ankle; spine; fracture and dislocation; rotator cuff tear; surgery; rehabilitation

(This special issue belongs to the Section Orthopedics)

Hernia Repair: Current Advances and Challenges

edited by Fabrizio D'Acapito and Daniela Di Pietrantonio

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1329 | Submission Open

Keywords: hernia mesh repair; TAPP; IPOM; TARUP; component separation; artificial intelligence; robotic surgery; laparoscopy; mesh infection

(This special issue belongs to the Section Surgery)

Psoriasis and Related Conditions: Recent Advances and Controversies

edited by

Alin Laurentiu Tatu

and

Elena Niculeţ

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1193 | Submission Open

Keywords: psoriasis; cytopathology; skin disorder; immunology; patient care

(This special issue belongs to the Section Dermatology)

Advanced Research in Clinical Pharmacology and Epidemiology

edited by Dnyandev Gadhave

submission deadline 31 Dec 2025 | 2 articles | Viewed by 947 | Submission Open

Keywords: clinical pharmacology; epidemiology; pharmacokinetics; pharmacodynamics; drug delivery

(This special issue belongs to the Section Epidemiology & Public Health)

Valve Diseases: Diagnosis and Treatment Innovations

edited by Vincenzo Caruso and Rajdeep Bilkhu

submission deadline 31 Dec 2025 | Viewed by 505 | Submission Open

Keywords: minimally invasive surgery; trans-catheter valve intervention; hybrid cardiac surgery; heart team; valve repair; Ross procedure; infective endocarditis

(This special issue belongs to the Section Cardiology)

Aortic Valve Replacement Innovations and Outcomes

edited by Basel Ramlawi and

Massimo Baudo

submission deadline 31 Dec 2025 | 1 articles | Viewed by 395 | Submission Open

Keywords: aortic valve replacement; cardiac surgery; minimally invasive; transcatheter; innovation; clinical outcomes; aortic stenosis; aortic regurgitation; technology

(This special issue belongs to the Section Cardiology)

Updates on Caries Management in the Primary and Permanent Dentition: 2nd Edition

edited by

Julian Schmoeckel

submission deadline 31 Dec 2025 | Viewed by 330 | Submission Open

Keywords: dental caries; treatment; caries management; children; adults; prevention; minimal-invasive

(This special issue belongs to the Section Dentistry and Oral Health)

Melanoma: Updates and Path Forward

edited by

Davide Melandri

and

Fortunato Cassalia

submission deadline 31 Dec 2025 | Viewed by 235 | Submission Open

Keywords: melanoma; epidemiology of skin cancer; social media and skin cancer prevention; early diagnosis; artificial intelligence in dermatology; genetic and epigenetic factors; melanoma oncogenesis; tumour microenvironment; dermatopathology; biomarkers; melanoma-mimicking tumours; immunotherapy; targeted therapy; personalised medicine

(This special issue belongs to the Section Dermatology)

Tissue-Guided Repair

edited by

Tiberiu Paul Neagu

and

Ileana Peride

submission deadline 31 Dec 2025 | Viewed by 136 | Submission Open

Keywords: tissue injury; tissue repair; chronic wound; wound healing; wound dressing; skin homeostasis; wound microenvironment; wound contraction; scar; skin substitutes; guided regeneration

(This special issue belongs to the Section Dermatology)

Advancements in Dental Medicine, Oral Anesthesiology and Surgery

edited by Cosmin Sinescu,

Ciprian Roi

and

Mircea Riviș

submission deadline 10 Jan 2026 | 8 articles | Viewed by 19658 | Submission Open

Keywords: oral surgery; oral anesthesiology; implantology and guided surgery; oral tissue regeneration; periodontal disease; dental materials; oral medical devices; oral diseases

(This special issue belongs to the Section Dentistry and Oral Health)

Advances in Diagnosis and Therapies of Ocular Diseases

edited by

Ana Maria Dascalu

submission deadline 10 Jan 2026 | 6 articles | Viewed by 8553 | Submission Open

Keywords: early biomarkers; retinal and optic nerve imaging; ocular surgery; glaucoma drainage devices; neuroprotection; refraction errors; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Diabetes, Hypertension, and Cardiovascular Diseases: New Insights, Risk Factors, and Drug Therapies

edited by

Christina Chrysohoou

Panagiotis Theofilis

and

Emmanouil Mantzouranis

submission deadline 10 Jan 2026 | 3 articles | Viewed by 6648 | Submission Open

Keywords: diabetes; hypertension; cardiovascular disease; cardiovascular risk factors; novel drug therapies; novel therapies; coronary artery disease; heart failure; precision medicine; artificial intelligence

(This special issue belongs to the Section Cardiology)

New Insights into Hypertension and the Cardiovascular System: 2nd Edition

edited by

Gwo-Ping Jong

submission deadline 15 Jan 2026 | Viewed by 178 | Submission Open

Keywords: hypertension; risk factors; oxidative stress; chronic inflammation; cardiovascular diseases

(This special issue belongs to the Section Cardiology)

Recent Advances in Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia

edited by

Apostolos Apostolidis

and Efstathios Papaefstathiou

submission deadline 20 Jan 2026 | 1 articles | Viewed by 1029 | Submission Open

Keywords: LUTS; BPH; minimally invasive treatment; digital health tools; biomarkers; microbiome

(This special issue belongs to the Section Urology & Nephrology)

Nutritional Management of Adults with Obesity

edited by

Alessandro Laviano

and

Salvatore Vaccaro

submission deadline 20 Jan 2026 | Viewed by 727 | Submission Open

Keywords: obesity; metabolic phenotype of obesity; nutritional management; nutritional intervention; nutritional educational program; precision nutrition; food compounds; dietary patterns; medical nutrition therapy (MNT); lifestyle intervention; physical activity program; traditional and innovative diets; therapeutic innovations

(This special issue belongs to the Section Endocrinology)

Craniomaxillofacial Surgery 4.0: Personalized Digital Planning, Augmented Reality, Point-of-Care Manufacturing and Molecular Data Integration

edited by

Maria J. Troulis

and

Manuel Tousidonis

submission deadline 20 Jan 2026 | Viewed by 142 | Submission Open

Keywords: craniomaxillofacial surgery; 3D printing; point-of-care manufacturing; microsurgery; reconstructive surgery; head and neck oncolog; rare jaw tumors; CCOC; minimally invasive surgery; tissue engineering; personalized digital planning; augmented reality; molecular data integration

(This special issue belongs to the Section Dentistry and Oral Health)

Minimally Invasive Procedures in Cardiac Care

edited by

Antonello D’Andrea

Vincenzo Russo

and

Alfredo Mauriello

submission deadline 24 Jan 2026 | 2 articles | Viewed by 5064 | Submission Open

Keywords: minimally invasive cardiac care; valve surgery; coronary artery bypass grafting; heart failure management; surgical techniques; implantable cardioverter defibrillator; pacemaker; stellate ganglion blockage; aortic valve; mitral valve; hybrid approaches

(This special issue belongs to the Section Cardiology)

Advancements and Outcomes in Transcatheter Aortic Valve Implantation (TAVI)

edited by Dimitrios Iliopoulos and

Nikolaos Schizas

submission deadline 25 Jan 2026 | 1 articles | Viewed by 788 | Submission Open

Keywords: TAVI; transcatheter aortic valve implantation; TAVR; aortic valve replacement; aortic valve stenosis

(This special issue belongs to the Section Cardiology)

Recent Advances and Future Challenges in Orthopaedic Trauma Surgery

edited by Zinon Kokkalis and

Dimitrios Ntourantonis

submission deadline 25 Jan 2026 | Viewed by 630 | Submission Open

Keywords: orthopaedic trauma; fracture fixation; polytrauma; non-union; geriatric fractures; implant design; surgical innovation; perioperative care; postoperative rehabilitation

(This special issue belongs to the Section Orthopedics)

Exercise Rehabilitation Strategies for Long-Term Conditions in the Post-Pandemic Era

edited by

David Varillas-Delgado

and Sofía Laguarta-Val

submission deadline 26 Jan 2026 | 2 articles | Viewed by 1920 | Submission Open

Keywords: therapeutic exercise; long covid; post-COVID syndrome; sports medicine; rehabilitation medicine; physiotherapy

(This special issue belongs to the Section Epidemiology & Public Health)

Minimally Invasive Strategies and New Techniques in Cardiovascular Surgery

edited by

Alexander Weymann

, Horatiu Suciu and

Marius Mihai Harpa

submission deadline 30 Jan 2026 | 1 articles | Viewed by 1168 | Submission Open

Keywords: minimally invasive; endoscopic surgery; mitral repair; mini-thoracotomy; hybrid approach; percutaneous therapy

(This special issue belongs to the Section Cardiology)

The Association Between Cardiovascular Disease and Lung Cancer

edited by

Francesk Mulita

and

Vasileios Leivaditis

submission deadline 30 Jan 2026 | Viewed by 137 | Submission Open

Keywords: cardiovascular disease; lung cancer; incidence; mortality; survival; radiotherapy; chemotherapy

(This special issue belongs to the Section Cardiology)

Medicine and Dentistry: New Methods and Clinical Approaches—2nd Edition

edited by

Stefano Rizza

and Rocco Franco

submission deadline 31 Jan 2026 | 16 articles | Viewed by 50816 | Submission Open

Keywords: oral health; new materials; medical approach; periodontal disease; bruxism; oral surgery

(This special issue belongs to the Section Dentistry and Oral Health)

Current and Future Trends in Dentistry and Oral Health

edited by

Eva Klarić

Bruno Špiljak

and

Luka Šimunović

submission deadline 31 Jan 2026 | 7 articles | Viewed by 19238 | Submission Open

Keywords: digital dentistry; artificial intelligence in dentistry; biomaterials; orthodontics; endodontics; periodontics; oral– systemic health; dental public health; esthetic dentistry; implantology

(This special issue belongs to the Section Dentistry and Oral Health)

Anterior Cruciate Ligament (ACL) Injury

edited by

Riccardo D'Ambrosi

and Alessandro Carrozzo

submission deadline 31 Jan 2026 | 6 articles | Viewed by 9810 | Submission Open

Keywords: anterior cruciate ligament; anterolateral ligament; arthroscopy; knee; sports medicine

(This special issue belongs to the Section Orthopedics)

Recent Advances in Anesthesiology and Pain Medicine

edited by Adam Rudnik and

Izabela Duda

submission deadline 31 Jan 2026 | 4 articles | Viewed by 9502 | Submission Open

Keywords: anesthetic procedures; perioperative monitoring; airway management; pain management; standards of anesthesia; perioperative care

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Novel Innovations in Diabetes Mellitus Prevention, Screening and Management

edited by

Anca Pantea Stoian

Teodor Salmen

and

Mihaela Adela Iancu

submission deadline 31 Jan 2026 | 4 articles | Viewed by 8456 | Submission Open

Keywords: diabetes mellitus; prevention; screening; complications; cardiovascular disease; neuropathy; retinopathy; nephropathy

(This special issue belongs to the Section Endocrinology)

Clinical Recent Research in Rehabilitation and Preventive Medicine

edited by Mihai Berteanu,

Marius Nicolae Popescu

and

Mădălina-Gabriela Iliescu

submission deadline 31 Jan 2026 | 3 articles | Viewed by 7565 | Submission Open

Keywords: physical medicine; rehabilitation; injury prevention; wearable sensor devices (WSDs); biomechanics; regenerative medicine; musculoskeletal ultrasound (MSKUS); AI in medicine; telehealth; motion analysis

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Cardiovascular Disease: From Clinical Diagnosis to Management and Treatment

edited by Florin Mitu,

Maria-Magdalena Leon

and

Alexandra Maștaleru

submission deadline 31 Jan 2026 | 3 articles | Viewed by 6363 | Submission Open

Keywords: cardiovascular disease; cardiac rehabilitation; secondary prevention; innovative treatment; risk stratification

(This special issue belongs to the Section Cardiology)

Clinical Treatment of Neuroendocrine Neoplasm

edited by Michele Klain and

Leandra Piscopo

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3366 | Submission Open

Keywords: neuroendocrine neoplasms; neuroendocrine cell system; gastro-entero-pancreatic NENs; immunohistochemical analysis; Ki-67 index; mitotic count; somatostatin analogue therapy; antiproliferative effect; positron emission tomography/computed tomography (PET/CT); peptide receptor radionuclide therapy (PRRT)

(This special issue belongs to the Section Oncology)

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