Diagnosis and Treatment of Thyroid Cancer in the Precision Medicine Era
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Oncology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 1251
Special Issue Editors
Interests: endocrine; thyroid cancer; endocrine oncology; neuroendocrine tumors; clinical endocrinology
Special Issue Information
Dear Colleagues,
Thyroid cancer (TC) is the most frequent endocrine malignancy, albeit it accounts for about 4% of all cancer types. The latest guidelines of the American Thyroid Association regarding Differentiated (DTC), Medullary (MTC), and Anaplastic Thyroid Cancer (ATC) provide thorough recommendations regarding the appropriate therapeutic management of TC patients (i.e., diagnostic assessment, surgical procedure, post-surgical treatment, and follow-up). Nevertheless, issues arise in real-life practice, especially when the physician has to deal with aggressive histological types and, moreover, when initial response to therapy is not excellent. Advanced forms of TC (i.e., metastatic Radioiodine Refractory DTC, MTC, and ATC) pose a challenge in clinical practice, and questions like when and where to use the available diagnostic tools and therapeutic options are of great importance to be answered towards precision medicine implementation. Tumor molecular profiling using Next Generation Sequencing (NGS) analysis, both on the tissue as well as on the Circulating Tumor DNA (ctDNA) and Circulating Tumor Cells (CTCs) level, is an intriguing tool providing information regarding prognosis and possible targeted-treatment options. In this Special Issue, we welcome original studies and reviews on the diagnosis, molecular pathways, and therapy of thyroid cancer. We especially welcome contributions focused on advanced TC, as described above, molecular pathways involved in TC pathogenesis and targeted treatment, and the clinical utility of molecular tools.
Dr. Maria Boudina
Guest Editor
Dr. George Simeakis
Guest Editor Assistant
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Keywords
- thyroid cancer
- molecular
- personalized
- targeted
- advanced thyroid cancer
- medullary
- liquid biopsy
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