Regenerative Dentistry: A New Paradigm in Oral Health Care

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Dentistry and Oral Health".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 35

Special Issue Editors


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Guest Editor
Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany
Interests: molecular methods; molecular mechanisms; oral diseases; bioengineering; tissue engineering; regenerative dentistry; oral microbiome; tissue regeneration
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Guest Editor Assistant
Faculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540139 Targu Mures, Romania
Interests: dentistry; periodontology; oral health; dental materials; caries

Special Issue Information

Dear Colleagues,

Regenerative dentistry is emerging as one of the most dynamic and transformative domains in contemporary oral health care. This development signifies a substantial departure from conventional restorative methodologies, which depend on inert materials and mechanical replacement, towards biologically driven approaches that aspire to restore structure, function, and vitality to damaged or diseased oral tissues. This Special Issue aspires to showcase the full breadth of innovation and clinical translation within the field, reflecting a novel paradigm in dentistry centered on regeneration, integration, and personalization.

This issue calls for pioneering research and critical reviews that explore the development, evaluation, and implementation of regenerative strategies across the spectrum of dental and craniofacial tissues, including dental pulp, dentin, periodontal ligaments, alveolar bone, oral mucosa, and temporomandibular structures.

Recent progress in stem cell biology, bioactive scaffolding, tissue engineering, and bioprinting, in conjunction with insights from immunology, molecular signaling, and clinical trial design, has facilitated the accelerated clinical adoption of regenerative therapies. Moreover, the convergence of three-dimensional (3D) technologies, omics platforms, and artificial intelligence (AI)-guided treatment planning facilitates the development of highly customized dental regeneration strategies.

We welcome original research articles, systematic reviews, and short communications that address both the experimental and clinical aspects of regenerative dental science. Submissions that explore interdisciplinary strategies or bridge the gap between bench and bedside are especially encouraged.

Dr. Raluca Cosgarea
Guest Editor

Dr. Felicia Gabriela Beresescu
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • regenerative dentistry
  • tissue engineering
  • stem cells
  • dental pulp regeneration
  • biomaterials
  • oral tissue repair
  • periodontal regeneration
  • craniofacial regeneration

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Published Papers

This special issue is now open for submission.
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