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Medicina
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Anesthesia and Analgesia in Surgical Practice: 2nd Edition
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Anesthesia and Analgesia in Surgical Practice: 2nd Edition

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Intensive Care/ Anesthesiology".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 3350

Editors

Dr. Sang Yoong Park

E-Mail Website
Guest Editor
Department of Anesthesiology and Pain Medicine, Dong-A University Hospital, 26 Daesingongwon-ro, Busan 49201, Republic of Korea
Interests: postoperative pain control; reduce opioid consumption; opioid induced hyperalgesia; regional anesthesia; peripheral nerve block
Special Issues, Collections and Topics in MDPI journals
Dr. Chan Jong Chung

E-Mail Website
Guest Editor
Department of Anesthesiology and Pain Medicine, Dong-A University Hospital, 26 Daesingongwon-ro, Busan 49201, Republic of Korea
Interests: pediatric anesthesia; airway management; meta-analysis; ultrasound guided procedure
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We consider now an appropriate time to look back at the development of anesthesia and analgesia, an area as old as the history of medicine itself. This Special Issue will bring together various and wide-ranging topics with the aim of sharing knowledge and opinions from experts in the field. The results of original studies and reviews will be presented, with a focus on anesthesia and analgesia in surgical practice.

This Special Issue will examine the techniques, technologies, and results of cutting-edge clinical, diagnostic, and therapeutic processes in the field of complications management after anesthesia. The editors invite contributions from recognized members of the anesthesia and analgesia community in the form of systematic reviews with or without meta-analysis, and observational or interventional original studies.

Dr. Sang Yoong Park
Dr. Chan Jong Chung
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric anesthesia
  • airway management
  • meta-analysis
  • ultrasound-guided procedures
  • postoperative pain control
  • reduce opioid consumption
  • opioid-induced hyperalgesia
  • regional anesthesia
  • peripheral nerve block

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Related Special Issue

Published Papers (4 papers)

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Research

14 pages, 1021 KB  
Article
Association Between Intraoperative Arterial Oxygen Tension and Postoperative Opioid Consumption: A Large-Scale Cohort Study Using Overlap Weighting Analysis
by Moon Ok Lee, Hanna Koh and Sung-Ae Cho
Medicina 2026, 62(7), 1318; https://doi.org/10.3390/medicina62071318 - 8 Jul 2026
Viewed by 331
Abstract
Background and Objectives: The clinical impact of hyperoxia, particularly its analgesic effects and potential pulmonary risks, remains controversial. This study investigated whether higher intraoperative arterial oxygen tension (PaO2) reduces postoperative analgesic requirements and its association with postoperative pulmonary complications (PPCs). [...] Read more.
Background and Objectives: The clinical impact of hyperoxia, particularly its analgesic effects and potential pulmonary risks, remains controversial. This study investigated whether higher intraoperative arterial oxygen tension (PaO2) reduces postoperative analgesic requirements and its association with postoperative pulmonary complications (PPCs). Materials and Methods: This retrospective cohort study included 1194 patients undergoing non-cardiac surgery. Patients were categorized into lower PaO2 (PaO2 ≤ 200 mmHg) and higher PaO2 (PaO2 > 200 mmHg) groups based on intraoperative arterial blood gas analysis. Overlap weighting was used to balance baseline characteristics and intraoperative variables. Primary outcomes included postoperative opioid consumption (measured in morphine milligram equivalents, MME) at 0–24 and 24–48 h. Secondary outcomes included pain intensity, frequency of rescue analgesics, the incidence of PPCs and in-hospital mortality. Results: After overlap weighting, the higher PaO2 group showed significantly lower strong opioid consumption during the 24–48 h period compared to the lower PaO2 group (0.22 ± 0.04 vs. 0.50 ± 0.11 MME; adjusted p = 0.014). The frequency of rescue analgesics was significantly reduced in the higher PaO2 group (1.04 ± 0.06 vs. 1.35 ± 0.11; adjusted p = 0.007). However, pain intensity and the total MME for 0–24 h did not differ. There was no significant difference in the incidence of total PPCs or total adverse events between the two groups. Conclusions: Higher intraoperative PaO2 was associated with a significant decrease in opioid requirements during the postoperative 24–48 h and frequency of rescue analgesics without increasing PPCs and adverse events. These findings support the need for prospective studies to determine whether higher intraoperative PaO2 may have a clinically meaningful role in perioperative analgesic strategies. Full article
(This article belongs to the Special Issue Anesthesia and Analgesia in Surgical Practice: 2nd Edition)
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11 pages, 1427 KB  
Article
Post-Thyroidectomy Nausea and Vomiting Using Continuous Remifentanil Infusion During Emergence Depending on the Inhaled Anesthetics: A Retrospective Cohort Study
by Ye Ji Hwang and Jeong Eun Lee
Medicina 2026, 62(7), 1304; https://doi.org/10.3390/medicina62071304 - 6 Jul 2026
Viewed by 407
Abstract
Background and Objectives: Immediately after thyroidectomy, retching driven by postoperative nausea and vomiting (PONV) may cause wound rupture, severe bleeding, and airway obstruction. Although inhaled anesthetics are widely used in thyroidectomy, they may increase the postoperative risk of PONV. Therefore, this study [...] Read more.
Background and Objectives: Immediately after thyroidectomy, retching driven by postoperative nausea and vomiting (PONV) may cause wound rupture, severe bleeding, and airway obstruction. Although inhaled anesthetics are widely used in thyroidectomy, they may increase the postoperative risk of PONV. Therefore, this study aimed to compare PONV incidence and recovery patterns according to the characteristics of sevoflurane (Sevo) and desflurane (Des) when remifentanil was continuously infused until extubation. Materials and Methods: This retrospective cohort study involved 70 female patients undergoing elective thyroidectomy, who were categorized into the Sevo (n = 35) and Des (n = 35) groups. Remifentanil was administered at an effect-site concentration of 2 ng/mL during emergence. Results: PONV incidence during emergence was 20% in both groups (p = 1.000). The Des group had shorter times to recovery of consciousness and extubation than the Sevo group (p < 0.001 and p < 0.001, respectively). At 5 min after extubation, patients in the Des group were more alert (p = 0.001), with 54.3% awake and responsive. Postanesthesia care unit stay was also shorter in the Des group (16.89 ± 3.22 vs. 23.74 ± 4.80; p < 0.001). Additionally, perioperative hemodynamic status, surgical site pain, and residual sedation did not differ between inhaled anesthetics. Conclusions: When remifentanil was infused until extubation after thyroidectomy, the choice of inhaled anesthetics did not affect the incidence of acute PONV. Des provided faster early recovery without additional side effects than Sevo; nonetheless, acute recovery profiles did not differ between inhaled anesthetics. Full article
(This article belongs to the Special Issue Anesthesia and Analgesia in Surgical Practice: 2nd Edition)
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9 pages, 737 KB  
Article
Comparison of Monitored Anesthesia Care with Target-Controlled Infusion and Sevoflurane Mask Anesthesia for Outpatient Gynecologic Surgery: A Single-Center Prospective Randomized Controlled Study
by Jaesuk Kim, Haneul Jeong and So Young Kwon
Medicina 2026, 62(3), 596; https://doi.org/10.3390/medicina62030596 - 21 Mar 2026
Viewed by 985
Abstract
Background and Objectives: Rapid recovery and patient comfort are key goals in ambulatory surgery. Although sevoflurane anesthesia is widely used, target-controlled infusion (TCI) with propofol and remifentanil has gained attention for its potential benefits. However, comparative data regarding recovery profiles and respiratory [...] Read more.
Background and Objectives: Rapid recovery and patient comfort are key goals in ambulatory surgery. Although sevoflurane anesthesia is widely used, target-controlled infusion (TCI) with propofol and remifentanil has gained attention for its potential benefits. However, comparative data regarding recovery profiles and respiratory safety remain limited. Materials and Methods: In this prospective randomized controlled trial, 51 ASA I–II patients undergoing outpatient gynecologic surgery were assigned to either a TCI group (n = 25) or an inhalation mask (IM) group using sevoflurane and nitrous oxide (n = 26). Primary outcomes included time to postanesthesia care unit (PACU) discharge readiness and patient and surgeon satisfaction. Secondary outcomes included eye-opening time, anesthesia duration, PACU stay, and respiratory adverse events. Results: Time to Aldrete score ≥9 did not differ significantly between groups (p = 0.697). The IM group demonstrated faster eye opening (p = 0.002), while patient satisfaction was higher in the TCI group (p < 0.001). Surgeon satisfaction favored the IM group (p = 0.035). Respiratory depression occurred more frequently in the TCI group (28.0% vs. 0%, p = 0.012). Conclusions: Sevoflurane anesthesia allowed faster emergence, whereas TCI provided greater patient satisfaction but increased respiratory risk. Both techniques are feasible for ambulatory gynecologic surgery when appropriately selected. Trial registration: This study was retrospectively registered at the Clinical Research Information Service (CRIS), Republic of Korea (KCT0011352). Full article
(This article belongs to the Special Issue Anesthesia and Analgesia in Surgical Practice: 2nd Edition)
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13 pages, 913 KB  
Article
Spinal Versus General Anesthesia for Lumbar Discectomy: Patient-Centered Analysis of Satisfaction with Anesthesia Service
by Marius Rimaitis, Diana Bilskienė, Kęstutis Rimaitis, Indrė Cirkelė and Andrius Macas
Medicina 2026, 62(3), 524; https://doi.org/10.3390/medicina62030524 - 12 Mar 2026
Cited by 1 | Viewed by 1042
Abstract
Background and Objectives: Spinal (SA) and general anesthesia (GA) are both available for lumbar disc hernia (LDH) surgery. Patient satisfaction with anesthesia service is under-investigated and may help identify areas requiring improvement, leading to better care. Materials and Methods: A prospective, non-randomized, survey-based [...] Read more.
Background and Objectives: Spinal (SA) and general anesthesia (GA) are both available for lumbar disc hernia (LDH) surgery. Patient satisfaction with anesthesia service is under-investigated and may help identify areas requiring improvement, leading to better care. Materials and Methods: A prospective, non-randomized, survey-based study was performed in patients who underwent LDH surgeries under SA or GA. Patients rated perioperative pain (preoperative and postoperative days (PODs) 0, 1, and 2) and satisfaction with perioperative care (10 questions) on a numeric rating scale (NRS) from 0 to 10, and an overall satisfaction score (OSS) was calculated; a patient discomfort questionnaire was also used. Study outcomes were pain scores, satisfaction with care, and discomfort reported by SA and GA patients. Results: In total, 209 completed questionnaires in the GA and SA groups (114 vs. 95) were available for final analysis. Baseline characteristics did not differ significantly between the two groups. The proportion of patients with severe pain decreased from >80% preoperatively to 6% on POD2, and pain scores did not differ significantly between groups. Mean overall satisfaction scores (OSSs) were high: 9.71 (maximum OSS: 57% of cases) in the GA group, and 9.75 (maximum OSS: 53.7% of cases) in the SA group (p = 0.95). The ceiling effect of the patient satisfaction questionnaire had to be addressed. There was no association between the type of anesthesia and OSS. Sources of discomfort were similar between groups, except for oropharyngeal discomfort being more prevalent in the GA group (p < 0.05). Postoperative pain was reported as a source of discomfort by >50% of patients in both the SA and GA groups. Regression analysis identified anxiety and nude body exposure as preoperative factors associated with decreased satisfaction with anesthesia. Postoperative factors associated with submaximal satisfaction were PONV, cold, mouth dryness, and pain. Pain on POD 0 did not influence overall patient satisfaction. An association was only found when pain persisted on POD 1 and POD 2. Conclusions: No significant differences between the two anesthesia methods were found. Patient information, anxiety management, and privacy protection are important for patient satisfaction. In the postoperative period, pain and PONV management must be equally addressed, irrespective of the anesthesia method used. Further efforts to develop optimal tools for patient satisfaction assessment are necessary. Full article
(This article belongs to the Special Issue Anesthesia and Analgesia in Surgical Practice: 2nd Edition)
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