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Medicina, Volume 62, Issue 2

2026 February - 188 articles

Cover Story: Vascularized Composite Allotransplantation (VCA) transplants multi-tissue units to reconstruct complex defects, and over 300 procedures have been performed in areas like the face, limb, and abdominal wall. A key innovation is the “sentinel flap” from abdominal wall VCA, which visually monitors rejection of co-transplanted solid organs. However, high acute rejection rates (up to 89%) due to skin immunogenicity necessitate intense immunosuppression, raising risks of infection and malignancy. The field also lacks standardized outcome measures. Future progress requires new immunomodulation strategies, machine perfusion technology, and standardized reporting frameworks to advance this promising but challenging field. View this paper
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Articles (188)

  • Review
  • Open Access
2 Citations
3,178 Views
15 Pages

Acquired Uterine Arteriovenous Fistulas After First-Trimester Pregnancy Loss: A Narrative Review with Case-Based Insights into Minimally Invasive Management

  • Răzvan-Grigoraș Căpitănescu,
  • Elena-Iuliana-Anamaria Berbecaru,
  • Anca-Maria Istrate-Ofițeru,
  • Marian-Valentin Zorilă and ,
  • Doru-Andrei Mitroi,
  • Gabriela-Camelia Roșu,
  • Dominic-Gabriel Iliescu,
  • Roxana-Cristina Drăgușin,
  • Laurențiu-Mihai Dîră and
  • George-Lucian Zorilă
  • + 6 authors+ 1 author

23 February 2026

Background and Objectives: Uterine arteriovenous fistulas (AVFs) and arteriovenous malformations (AVMs) are rare but potentially life-threatening vascular anomalies that most commonly develop after pregnancy-related uterine trauma, such as curettage...

(This article belongs to the Special Issue Recent Advances in Gynecological Surgery)
  • Article
  • Open Access
2 Citations
1,431 Views
14 Pages

Predicting Mortality in Pulmonary Embolism: A Machine Learning Approach with External Validation in COVID-19 Patients

  • Diana Alexandra Mîțu,
  • Alexandru Cristian Cindrea,
  • Alexandra Maria Borita,
  • Adina Maria Marza and ,
  • Corneluța Fira-Mladinescu,
  • Madalin-Marius Margan,
  • Alexandra Herlo,
  • Alina Petrica,
  • Gabriel-Aurel Rus and
  • Ovidiu Alexandru Mederle
  • + 7 authors+ 2 authors

23 February 2026

Background and Objectives: Pulmonary embolism (PE) is a frequent thrombotic complication associated with SARS-CoV-2 infection and is linked to significant early mortality. Accurate early risk stratification in the emergency department (ED) remains ch...

(This article belongs to the Section Intensive Care/ Anesthesiology)
  • Review
  • Open Access
3 Citations
2,215 Views
15 Pages

Advances in Imaging and Physiology-Guided Personalized Care in Acute Respiratory Distress Syndrome

  • Lucas Rodrigues Moraes,
  • Pedro Leme Silva,
  • Denise Battaglini and
  • Patricia Rieken Macedo Rocco

23 February 2026

Acute respiratory distress syndrome (ARDS) is a heterogeneous inflammatory lung injury marked by increased alveolar–capillary permeability, reduced respiratory system compliance, and impaired gas exchange. Despite advances in supportive care, A...

(This article belongs to the Section Pulmonology)
  • Article
  • Open Access
1,746 Views
14 Pages

23 February 2026

Background and objectives: Antiseizure medications are essential for epilepsy management but often cause adverse effects that impact treatment adherence and quality of life. This study investigates the incidence rate and determinants of high-burden a...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
3 Citations
2,477 Views
12 Pages

Verification of Markerless Gait Analysis: Multi-Camera and Single-Camera Approaches in Comparison to Marker-Based Gait Analysis

  • Yong Seok Park,
  • Yeon Woo Yu,
  • Hari Cha,
  • Joon Seok Lee and ,
  • Chan Yoon,
  • Byung-Hoon Kim,
  • Jae Hyeon Park and
  • Ki-Kwang Lee
  • + 3 authors+ 0 author

22 February 2026

Background and Objectives: This study aimed to verify the validity of markerless gait analysis using both single-camera markerless system (S-ML) and multi-camera markerless system (M-ML) approaches by comparing them with a gold-standard marker-based...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
820 Views
15 Pages

Does the Laparoscopic Approach Reduce the Incidence of Vesicourethral Anastomotic Stricture Compared with the Open Approach After Radical Prostatectomy in Patients with Microangiopathic Risk Factors?

  • Alexandru-Ionuț Cherciu,
  • Mihai-Cristian Persu,
  • Andrei-Cosmin Bumbea,
  • Mădălina-Maria Cherciu and ,
  • Mihnea Cristian Firoiu,
  • Radu Tiberiu Vrabie,
  • Emilian Bolovan,
  • Dragoș Mihail Arbunea,
  • Darius Marian Brînzan and
  • Ovidiu-Gabriel Bratu
  • + 7 authors+ 2 authors

22 February 2026

Background: Vesicourethral anastomotic stricture (VUAS) remains a clinically relevant complication following radical prostatectomy, with important implications for postoperative urinary function. Minimally invasive approaches may offer technical adva...

(This article belongs to the Section Urology & Nephrology)
  • Perspective
  • Open Access
2 Citations
3,077 Views
15 Pages

Erectile and Clitoral Dysfunction as Harbingers of Cardiovascular Disease: A Perspective

  • Fernanda Priviero,
  • Fiona Hollis,
  • Susan K. Wood,
  • Mark Uline and ,
  • Karl-Erik Andersson and
  • R. Clinton Webb
  • + 1 author+ 0 author

22 February 2026

Sexual dysfunction (SD), more specifically vasculogenic erectile dysfunction (ED) in men and female sexual arousal disorder (FSAD) in women, is increasingly recognized as a marker of cardiovascular disease (CVD). While extensive literature documents...

(This article belongs to the Special Issue Clinical Diagnosis and Management of Cardiovascular Disease)
  • Review
  • Open Access
1 Citations
2,635 Views
22 Pages

Confocal Laser Endomicroscopy: Real-Time Histology at the Fingertips: A Comprehensive Review of Current Applications of Endomicroscopy in Barrett Esophagus, Inflammatory Bowel Disease, and Colorectal Lesions

  • Eyad Gadour,
  • Bogdan Miutescu,
  • Abed Al-Lehibi,
  • Mustafa Mohamed and ,
  • Emad Aljahdli,
  • Mohammed Albeshir,
  • Alexandru Popa,
  • Bodour Raheem and
  • Antonio Facciorusso
  • + 4 authors+ 0 author

22 February 2026

Confocal laser endomicroscopy (CLE) is an innovative diagnostic modality that facilitates real-time in vivo optical biopsies of various tissues within luminal and ductal structures. Since its introduction in 2004, the application of this tool has bro...

(This article belongs to the Special Issue Recent Advances in Digestive Endoscopy)
  • Article
  • Open Access
1 Citations
1,137 Views
11 Pages

Association of Non-Dipping Blood Pressure Patterns with Fetal Growth Restriction and Postpartum Chronic Hypertension in Gestational Hypertension

  • Ümeyir Savur,
  • Ersin İbişoğlu,
  • Haci Murat Güneş,
  • Saime Güneş and ,
  • Aykun Hakgor and
  • Aysel Akhundova
  • + 1 author+ 0 author

22 February 2026

Background and Objectives: Gestational hypertension (GH) is increasingly recognized as an early manifestation of maternal cardiovascular vulnerability. Ambulatory blood pressure monitoring (ABPM) enables the evaluation of circadian blood pressure beh...

(This article belongs to the Section Obstetrics and Gynecology)
  • Article
  • Open Access
1 Citations
1,668 Views
18 Pages

Towards Rapid Bedside Detection of Sarcopenia in Cancer Patients: The Role of Rectus Femoris Muscle Ultrasonography—A Prospective Cross-Sectional Study

  • Süleyman Baş,
  • Hasan Hakan Çoban,
  • Akif Doğan,
  • Hande Nur Erölmez and ,
  • Hasan Hüseyin Mutlu and
  • Nurullah İlhan
  • + 1 author+ 0 author

21 February 2026

Background and Objectives: Sarcopenia is a common yet underrecognized condition in cancer patients and is associated with increased treatment-related toxicity, functional decline, and poor clinical outcomes. Practical, rapid, and bedside-applicable t...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
1 Citations
1,391 Views
20 Pages

Development and Internal Evaluation of an Interpretable AI-Based Composite Score for Psychosocial and Behavioral Screening in Dental Clinics Using a Mamdani Fuzzy Inference System

  • Alexandra Lavinia Vlad,
  • Florin Sandu Blaga,
  • Ioana Scrobota,
  • Raluca Ortensia Cristina Iurcov and ,
  • Gabriela Ciavoi,
  • Anca Maria Fratila and
  • Ioan Andrei Țig
  • + 2 authors+ 0 author

21 February 2026

Background and Objectives: Psychosocial symptoms and oral behaviors can complicate routine dental care, yet available screeners yield multiple separate scores. Explainable artificial intelligence offers a pragmatic way to integrate such multidomain m...

(This article belongs to the Special Issue Application of Artificial Intelligence in Disease Diagnosis and Treatment)
  • Article
  • Open Access
1 Citations
1,068 Views
17 Pages

Diabetes Mellitus and In-Hospital Outcomes in Hospitalized COVID-19 Patients: A Single-Center Eastern European Cohort Study (2020–2024)

  • Ioana-Georgiana Cotet,
  • Ana-Olivia Toma,
  • Diana-Maria Mateescu,
  • Adrian-Cosmin Ilie and ,
  • Sorin Ursoniu,
  • Dan Alexandru Surducan,
  • Cosmin Gridan,
  • Stela Iurciuc,
  • Dragos-Mihai Gavrilescu and
  • Cristina Tudoran
  • + 5 authors+ 0 author

21 February 2026

Background and Objectives: Diabetes mellitus (DM) has been consistently linked to severe coronavirus disease 2019 (COVID-19) and adverse outcomes; however, the extent to which DM independently predicts mortality and cardiovascular complications in re...

(This article belongs to the Special Issue Cardiovascular Diseases and Type 2 Diabetes: 2nd Edition)
  • Article
  • Open Access
1,391 Views
13 Pages

Junctional Failures Following Long-Level Fusion to L5 in Elderly Patients: Impact of Spinopelvic Alignment and L5–S1 Disc Degeneration

  • In-Seok Son,
  • Yong-Chan Kim,
  • Sung-Min Kim,
  • Xiongjie Li and ,
  • Maolin Jin,
  • Young-Jik Lee,
  • Seung-Hyun Sim and
  • Kee-Yong Ha
  • + 3 authors+ 0 author

21 February 2026

Background and Objectives: Long spinal fusion terminating at L5 remains controversial because of the risk of postoperative junctional failure. Although degeneration of the residual L5–S1 disc has been suggested as a contributing factor, the rel...

(This article belongs to the Special Issue Orthopedic Trauma: Surgical Treatment and Rehabilitation)
  • Article
  • Open Access
3 Citations
1,851 Views
11 Pages

20 February 2026

Background and Objectives: Intra-articular injection of adipose-derived stromal vascular fraction (SVF) has emerged as a promising regenerative treatment for knee osteoarthritis (OA) because of its heterogeneous cellular composition and potent anti-i...

(This article belongs to the Section Orthopedics)
  • Systematic Review
  • Open Access
2 Citations
2,063 Views
19 Pages

Global Burden of Trichostrongylus Infections in Humans: A Systematic Review and Meta-Analysis

  • Jurairat Jongthawin,
  • Kinley Wangdi,
  • Aongart Mahittikorn,
  • Frederick Ramirez Masangkay and
  • Manas Kotepui

20 February 2026

Trichostrongylus species are zoonotic gastrointestinal nematodes that occasionally infect humans, particularly in rural areas with close contact to livestock. However, the global prevalence of human trichostrongylosis remains uncertain. This systemat...

(This article belongs to the Section Infectious Disease)
  • Article
  • Open Access
1,590 Views
11 Pages

Evaluation of Serum Calprotectin Levels and Their Relationship with Disease Activity in Psoriatic Arthritis and Axial Spondyloarthritis

  • Emre Ali Acar,
  • Sadettin Uslu,
  • Semih Gülle,
  • Muhammet Nurullah Yiğit and ,
  • Cevval Ulman and
  • Timur Pırıldar
  • + 1 author+ 0 author

20 February 2026

Background and Objectives: Psoriatic arthritis (PsA) is a chronic inflammatory arthritis characterized by marked clinical heterogeneity and variable disease trajectories, underscoring the need for robust biomarkers of inflammatory burden. Serum calpr...

(This article belongs to the Section Hematology and Immunology)
  • Article
  • Open Access
1,730 Views
18 Pages

Histological and Immunohistochemical Characterization of the Tibial ACL Remnant: Implications for Ligament Healing

  • Sorin Florescu,
  • Blidişel Iulian Alexandru,
  • George Andrei Drăghici,
  • Dragoş Vasile Nica and ,
  • Boru Casiana and
  • Cosmin Grațian Damian
  • + 1 author+ 0 author

20 February 2026

Background and Objectives: The pathways mediating the beneficial effect of tibial stump preservation for anterior cruciate ligament (ACL) reconstruction remain insufficiently clarified. This study investigated key vascular, neural, and stromal aspect...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
1 Citations
3,721 Views
32 Pages

Hyaluronic Acid Profhilo® Alleviates Skin Inflammation and Spinal Neuroimmune Alterations in a Mouse Model of Atopic Dermatitis

  • Gabriel Siquier-Dameto,
  • Javier Gimeno-Beltrán,
  • Gilberto Bellia,
  • Andrea Giori and ,
  • Pere Boadas-Vaello and
  • Enrique Verdú
  • + 1 author+ 0 author

20 February 2026

Background and Objectives: Hyaluronic acid (HA) is extensively used in dermo-aesthetic medicine for its hydrating and tissue-repairing properties. Beyond cosmetic use, HA has shown therapeutic effects in inflammatory skin diseases such as seborrheic,...

  • Article
  • Open Access
1 Citations
1,540 Views
16 Pages

Assessing the Long-Term Impact of the COVID-19 Pandemic on Hospital Outcomes in Patients with Decompensated Liver Cirrhosis

  • Melania Veronica Ardelean,
  • Ovidiu Florin Ardelean,
  • Dana Roxana Buzas,
  • Paul Ciubotaru and ,
  • Vlad Ivan,
  • Alin Viorel Istodor,
  • Daniel Florin Lighezan and
  • Norina Simona Basa
  • + 3 authors+ 0 author

19 February 2026

Background and Objectives: The COVID-19 pandemic profoundly disrupted global healthcare systems, limiting access to diagnostic and therapeutic services for chronic diseases. Patients with decompensated liver cirrhosis were particularly vulnerable due...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
1 Citations
1,783 Views
14 Pages

Sleep Quality in Patients with Epilepsy: Differences in Anxiety, Depression, and Clinical Characteristics

  • Silvija Bartašiūnaitė,
  • Dovydas Burkojus,
  • Agnė Šmigelskytė,
  • Giedrė Jurkevičienė and
  • Giedrė Gelžinienė

19 February 2026

Background and Objectives: People with epilepsy frequently complain of poor sleep quality, excessive daytime sleepiness (EDS), and insomnia. Therefore, this study aimed to evaluate differences in anxiety and depression symptoms, as well as clinical c...

(This article belongs to the Section Neurology)
  • Article
  • Open Access
1 Citations
1,516 Views
16 Pages

Clinical and Functional Heterogeneity of COPD Phenotypes: A Multicenter Study from Turkey (DIPTUR Study)

  • Tevfik Ozlu,
  • Ozlem Sengoren Dikis,
  • Fulden Cantas Turkis,
  • Ceren Degirmenci and ,
  • Ahmet Ilgazlı,
  • Inci Gülmez,
  • Burcu Yalcin,
  • Gulistan Karadeniz,
  • Yasemin Soyler and
  • Gamze Celik
  • + 38 authors+ 33 authors

19 February 2026

Background and Objectives: Chronic obstructive pulmonary disease (COPD) is heterogeneous, and phenotype-based classification may better capture differences in clinical burden and healthcare needs beyond standard GOLD categories. We aimed to describe...

(This article belongs to the Special Issue New Trends in Chronic Obstructive Pulmonary Disease (COPD))
  • Review
  • Open Access
1 Citations
3,703 Views
21 Pages

Maternal Cardiovascular Emergencies During Pregnancy and the Puerperium: Current Diagnostic Approach and Management

  • Alexandra Arvanitaki,
  • Christos Kalimanis,
  • Athina Nasoufidou,
  • Marios G. Bantidos and ,
  • Efstratios Karagiannidis,
  • Michail Kalinderis,
  • Nikolaos Fragakis,
  • Barbara Fyntanidou and
  • Ioannis Tsakiridis
  • + 4 authors+ 0 author

19 February 2026

Physiologic changes during pregnancy, advanced maternal age, and cardiovascular comorbidities have been associated with an increased incidence of cardiovascular emergencies (CVEs) manifesting during pregnancy and puerperium, thereby adversely affecti...

(This article belongs to the Special Issue Acute Cardiovascular Events: Broadening Perspectives in Acute Care)
  • Systematic Review
  • Open Access
1 Citations
2,109 Views
19 Pages

The Relative Efficacy of Monotherapies for Palmoplantar Pustulosis and Palmoplantar Psoriasis: A Network Meta-Analysis Study of the Palmoplantar Spectrum

  • Aditya K. Gupta,
  • Mary A. Bamimore,
  • Tong Wang,
  • Tina Bhutani and ,
  • Vincent Piguet and
  • Mesbah Talukder
  • + 1 author+ 0 author

19 February 2026

Background and Objectives: Palmoplantar pustulosis (PPPust) and palmoplantar psoriasis (PPso) are distinct palm/sole dermatoses that have historically shared the abbreviation “PPP”. Though the two—since the advent of advanced biotec...

(This article belongs to the Section Dermatology)
  • Article
  • Open Access
1 Citations
870 Views
14 Pages

19 February 2026

Background and Objectives: The prognostic significance of pelvic lymph node (PLN) count in surgically staged endometrial cancer remains controversial. This study aimed to evaluate the impact of PLN count on overall survival (OS), disease-free surviva...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
1,401 Views
12 Pages

19 February 2026

Background and Objectives: With the increasing demand for gender-affirming procedures, facial feminization surgery (FFS) has become an essential component in the management of patients with gender dysphoria. In this study, ‘male’ and &lsq...

(This article belongs to the Special Issue Oral and Maxillofacial Surgery: Current Trends, Therapeutic Approaches and Future Directions)
  • Article
  • Open Access
733 Views
14 Pages

Associations Between Coronal Alignment, Patellar Height, Chondrocalcinosis and Radiographic Severity of Knee Osteoarthritis in a Single-Center Cross-Sectional Clinical Cohort

  • Laszlo Irsay,
  • Theodor Popa,
  • Madalina Gabriela Iliescu,
  • Cosmina Ioana Bondor and ,
  • Alina Deniza Ciubean and
  • Viorela Mihaela Ciortea
  • + 1 author+ 0 author

18 February 2026

Background and Objectives: Knee osteoarthritis (OA) is a leading cause of pain and disability, with radiographic severity influenced by age, biomechanical alignment, and structural joint features. Data describing the association between common radiog...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
779 Views
20 Pages

18 February 2026

Background and Objectives: Anatomical staging alone insufficiently explains survival heterogeneity in patients with resected non-small cell lung cancer (NSCLC). Although inflammation-based biomarkers have demonstrated prognostic value, the clinical r...

(This article belongs to the Special Issue Thoracic Oncology: Current Challenges and Future Prospects)
  • Review
  • Open Access
1,078 Views
12 Pages

18 February 2026

Sudden unexplained cardiac death (SUCD) is unpredictable, causing major emotional, economic, and productivity loss. In young, apparently healthy individuals, it remains one of the most challenging causes of mortality to understand mechanistically, an...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
1,161 Views
14 Pages

Using Machine Learning Methods to Predict Hospitalization Based on Brixia Score and Patient Clinical Data (from the COVID-19 Pandemic)

  • Mirela Juković,
  • Aleksandra Mijatović,
  • Radmila Perić,
  • Ljiljana Dražetin and ,
  • Dijana Nićiforović and
  • Dejan B. Stojanović
  • + 1 author+ 0 author

17 February 2026

Background and Objectives: The use of a standard chest X-ray has become a routine diagnostic method in daily clinical practice for the evaluation of a wide range of lung diseases. During the COVID-19 pandemic, significant challenges occurred in achie...

(This article belongs to the Section Infectious Disease)
  • Article
  • Open Access
4 Citations
1,600 Views
11 Pages

17 February 2026

Background: Diabetic foot ulceration represents one of the most severe diabetic complications, with 50–60% progressing to diabetic foot infection (DFI). All diabetic wounds and diseases originate from peripheral vasculopathy and neuropathy, whi...

(This article belongs to the Section Infectious Disease)
  • Article
  • Open Access
922 Views
19 Pages

Inguinal Hernia Recurrence in Adults in Romania: A Five-Year Nationwide Analysis of Surgical Practice and Health System Disparities

  • Anca Tigora,
  • Dragos Garofil,
  • Mihai Zurzu,
  • Vlad Paic and ,
  • Mircea Bratucu,
  • Florian Popa,
  • Valeriu Surlin,
  • Sandu Ramboiu,
  • Daniela Marinescu and
  • Petru Radu
  • + 6 authors+ 1 author

17 February 2026

Introduction: Recurrent inguinal hernia remains a clinically relevant outcome that is difficult to quantify in the absence of national prospective registries. In Romania, structural differences between public and private hospitals may further influen...

(This article belongs to the Special Issue Abdominal Surgery: Clinical Updates and Future Perspectives)
  • Article
  • Open Access
1,339 Views
13 Pages

Radiological Assessment of Frontal Recess Cells and Their Association with Frontal Sinusitis Among Omani Subjects: A Single-Center Computed Tomography-Based Study

  • Srinivasa Rao Sirasanagandla,
  • Noor Fazaldad,
  • Faiza Al Hajri,
  • Tariq Al Habsi and ,
  • Mohammed Al Washahi,
  • Muataz Al Siyabi and
  • Eiman Al-Ajmi
  • + 2 authors+ 0 author

17 February 2026

Background and Objectives: Frontal recess cells (FRCs) are key anatomical variants influencing frontal sinus drainage and disease. The International Frontal Sinus Anatomy Classification (IFAC) provides a standardized system for their identification....

(This article belongs to the Special Issue Clinical Anatomy in the 21st Century: Understanding the Possible Basis of Certain Pathologies and Clinical Symptoms)
  • Article
  • Open Access
959 Views
10 Pages

Indoor Employment as a Factor Associated with Vitamin D Levels in Obstructive Sleep Apnoea Syndrome

  • Evangelia Nena,
  • Kostas Archontogeorgis,
  • Maria Katsaouni,
  • Konstantina Chadia and ,
  • Athanasios Voulgaris and
  • Paschalis Steiropoulos
  • + 1 author+ 0 author

16 February 2026

Background and Objectives: Variations in serum 25-hydroxyvitamin D [25(OH)D] concentrations have been described among individuals working in different settings. Moreover, published evidence suggests an association between Obstructive Sleep Apnea Synd...

  • Systematic Review
  • Open Access
4 Citations
3,812 Views
18 Pages

Psychological Disorder and Patient Satisfaction in Aesthetic Surgery—A Systematic Review

  • Lavinia Hogea,
  • Brenda Bernad,
  • Amalia Marinca,
  • Leonardo Corsaro and ,
  • Iuliana Costea,
  • Nina Ivanovic and
  • Teodora Anghel
  • + 2 authors+ 0 author

16 February 2026

Background and Objectives: This systematic review investigates the relationship between preoperative psychological disorders and postoperative satisfaction among patients undergoing aesthetic surgery. While aesthetic procedures can enhance self-image...

(This article belongs to the Section Psychiatry)
  • Article
  • Open Access
1 Citations
1,726 Views
13 Pages

Self-Perceived Prevalence of Functional Ankle Instability and Associated Factors Among Male Volleyball Players in Qassim Region

  • Maram Ibrahim Mebrek AlMebrek,
  • Salma Abdulmohsen Altoyan,
  • Ahmad Alanazi,
  • Msaad Alzhrani and ,
  • Sultan A. Alanazi and
  • Mahamed Ateef
  • + 1 author+ 0 author

16 February 2026

Background and Objectives: Functional Ankle Instability (FAI) is a sequela of ankle sprains; however, its associated variables in volleyballers have not been studied. This study aimed to determine the prevalence of FAI and the association between FAI...

(This article belongs to the Section Sports Medicine and Sports Traumatology)
  • Article
  • Open Access
2 Citations
2,095 Views
10 Pages

Preliminary Real-World Experience with Semaglutide in Obese Patients with Type 2 Diabetes on Chronic Hemodialysis: A Multicenter Pilot Study

  • Alejandra Yugueros,
  • Luis D’Marco,
  • Alejandro Valero,
  • Elena Vivó and ,
  • Amparo Martínez-Mas,
  • Manuel Calvé,
  • Juan Carlos Alonso,
  • Belén Vizcaíno,
  • Mercedes González-Moya and
  • Pablo Molina
  • + 7 authors+ 2 authors

16 February 2026

Background and Objectives: Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1RA) that has demonstrated metabolic and weight benefits in diabetic and obese patients with chronic kidney disease (CKD) who are not on dialysis; however, evid...

(This article belongs to the Special Issue End-Stage Kidney Disease (ESKD))
  • Article
  • Open Access
1 Citations
1,304 Views
10 Pages

Extent of Resection and Survival in IDH-Wildtype Glioblastoma: A Dual-Center Retrospective Study

  • Selami Bayram,
  • Mustafa Serkan Alemdar,
  • Ali Murat Tatli,
  • Derya Kivrak Salim and ,
  • Banu Ozturk,
  • Muharrem Okan Cakir and
  • Mustafa Ozdogan
  • + 2 authors+ 0 author

15 February 2026

Background and Objectives: Glioblastoma (GBM), defined as IDH-wildtype CNS WHO grade 4, remains the most common and aggressive primary malignant brain tumor in adults. Although the extent of resection (EOR), particularly gross total resection (GTR),...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
1,227 Views
24 Pages

Brain-Derived Neurotrophic Factor Deficiency Exacerbates Innate Immune Responses by Enhancing NLRP3 Inflammasome Activation and GSDMD-Mediated Pyroptosis in Mice

  • Şeniz Erdem,
  • Neslihan Sağlam,
  • Elif Şahin,
  • Mehmet Erdem and ,
  • İsmail Abidin and
  • Ahmet Alver
  • + 1 author+ 0 author

14 February 2026

Background and Objectives: The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a key innate immune complex, and its aberrant activation contributes to metabolic and neurodegenerative diseases. Brain-derived neurotrophic fac...

(This article belongs to the Section Genetics and Molecular Medicine)
  • Retraction
  • Open Access
531 Views
1 Page

14 February 2026

The journal retracts the article titled “Effect of Education on Adherence to Recommended Prenatal Practices among Indigenous Ngäbe–Buglé Communities of Panama” [...]

  • Article
  • Open Access
3 Citations
2,455 Views
15 Pages

Dysphonia in Occupational Voice Users: Risk Factors, Causes and Socioepidemiological Profiles

  • Jasmina Stojanovic,
  • Snezana Radovanovic,
  • Milica Jevtic,
  • Strahinja Krsmanovic and ,
  • Marina Jovanovic,
  • Andra Jevtovic,
  • Snezana Babac,
  • Mila Veselinovic,
  • Mila Bojanovic and
  • Nenad Relic
  • + 9 authors+ 4 authors

14 February 2026

Background and Objectives: Professional voice users (PVUs) are individuals for whom the voice is the primary tool of work, and whose professional success and income largely depend on its quality. This paper’s study population predominantly cons...

(This article belongs to the Section Epidemiology & Public Health)
  • Article
  • Open Access
1,599 Views
17 Pages

3D-Printed Versus Conventional Dental Provisional Resins: A Comparative Study

  • Olívia Breda Moss,
  • Anselmo Agostinho Simionato,
  • Adriana Cláudia Lapria Faria,
  • Renata Cristina Silveira Rodrigues and
  • Ricardo Faria Ribeiro

14 February 2026

Background and Objectives: This study aimed to evaluate and compare the effects of immersion and brushing on resins used for temporary crowns, including two 3D-printed resins (Nanolab and PrintaX) and one self-curing resin (Duralay), with different s...

(This article belongs to the Topic Advances in Dental Materials)
  • Review
  • Open Access
1 Citations
2,193 Views
20 Pages

Heart Failure in Rheumatoid Arthritis: Epidemiology, Pathogenesis, Diagnosis, Treatment, and Emerging Insights—A Comprehensive Review

  • Goran Šukara,
  • Josip Tečer,
  • Ivana Jurin,
  • Majda Golob and ,
  • Marko Barešić and
  • Joško Mitrović
  • + 1 author+ 0 author

14 February 2026

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease associated with an increased risk of cardiovascular complications, including heart failure (HF). HF represents a major cause of morbidity and mortality among patients with RA, cont...

(This article belongs to the Special Issue Rheumatoid Arthritis: Advances in Diagnosis, Treatment and Prognosis in Clinical Medicine)
  • Article
  • Open Access
2 Citations
852 Views
18 Pages

14 February 2026

Background and Objectives: The risk of cardiovascular events rises when hypertensive patients fail to achieve sufficient blood pressure reduction during nighttime hours. This study examined the association between metabolic and inflammatory biomarker...

(This article belongs to the Section Urology & Nephrology)
  • Article
  • Open Access
2 Citations
1,546 Views
11 Pages

14 February 2026

Background and Objectives: Neuroleptic malignant syndrome (NMS) is a rare but high-mortality clinical condition. The aim of this study was to describe the demographic characteristics, clinical and laboratory findings, management strategies, and clini...

(This article belongs to the Section Intensive Care/ Anesthesiology)
  • Article
  • Open Access
1,132 Views
12 Pages

Role of Prognostic Nutritional Index and C-Reactive Protein/Albumin Ratio in Prognosis of Locally Advanced Nasopharyngeal Carcinoma

  • Taliha Güçlü Kantar,
  • Tolga Doğan,
  • Burçin Çakan Demirel,
  • Melek Özdemir and ,
  • Semra Taş,
  • Bedriye Açıkgöz Yıldız,
  • Gamze Serin Özel,
  • Ceren Mordağ Çiçek,
  • Burcu Yapar Taşköylü and
  • Gamze Gököz Doğu
  • + 8 authors+ 3 authors

14 February 2026

Background and Objectives: Nasopharyngeal carcinoma (NPC) is a distinct type of head and neck cancer with unique epidemiological and pathological characteristics. Inflammatory and nutritional markers have been increasingly recognized as prognostic in...

(This article belongs to the Section Oncology)
  • Article
  • Open Access
3 Citations
1,663 Views
13 Pages

Sperm DNA Fragmentation Is Associated with Impaired Directional Motility and Kinematic Efficiency: A CASA-Based Study

  • Ioana Cristina Rotar,
  • Richard Buda,
  • Adelin Marcu,
  • Petronela Naghi and ,
  • Liliana Sachelarie,
  • David Călin Buzlea,
  • Anca Huniadi and
  • Mircea Ioan Sandor
  • + 3 authors+ 0 author

13 February 2026

Background and Objectives: Sperm DNA fragmentation (SDF) has emerged as an important marker of male reproductive potential; however, its relationship with sperm kinematic performance remains incompletely understood. While conventional semen analysis...

(This article belongs to the Special Issue Advances in Reproductive Health)
  • Review
  • Open Access
2 Citations
1,988 Views
38 Pages

Pulp–Dentin Regeneration via Cell Homing: Current Evidence and Perspectives on Cell-Free Regenerative Endodontic Therapy

  • Michele Beco,
  • Francesca Di Pasquale,
  • Chiara Valenti,
  • Paolo Betti and ,
  • Gian Luca Mascolo,
  • Lorella Marinucci,
  • Stefano Eramo and
  • Stefano Pagano
  • + 3 authors+ 0 author

13 February 2026

Background and Objectives: The regeneration of the pulp–dentin complex represents an alternative to conventional root canal treatment, aiming to preserve tooth biology and function. Cell-free regenerative endodontic therapy (CF-RET) exploits en...

(This article belongs to the Section Dentistry and Oral Health)
  • Article
  • Open Access
1 Citations
1,063 Views
18 Pages

Cardioplegia Strategies in Minimally Invasive Aortic Valve Replacement: An Inverse Probability of Treatment Weighting Analysis

  • Lukman Amanov,
  • Sadeq Ali-Hasan-Al-Saegh,
  • Arian Arjomandi Rad,
  • Antonia Annegret Jauken and ,
  • Prokopis-Andreas Zotos,
  • Jawad Salman,
  • Thanos Athanasiou,
  • Ezin Deniz,
  • Stefan Ruemke and
  • Alexander Weymann
  • + 8 authors+ 3 authors

13 February 2026

Background and Objectives: Optimal myocardial protection during minimally invasive aortic valve replacement (MIAVR) is debated. We compared four cardioplegia strategies. Materials and Methods: Consecutive MIAVR patients (January 2010–April 2025...

(This article belongs to the Special Issue Clinical Research in Minimally Invasive Cardiac Surgery)
  • Article
  • Open Access
1 Citations
856 Views
20 Pages

13 February 2026

Background and Objectives: Colorectal cancer (CRC) is the most common gastrointestinal malignancy in Oman and among the top three cancers nationally, with an increasing burden of early-onset CRC (EOCRC) diagnosed before age 50. Despite national CRC g...

(This article belongs to the Section Gastroenterology & Hepatology)

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Medicina - ISSN 1648-9144