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Medicina
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Clinical Anatomy in the 21st Century: Understanding the Possible Basis...
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Clinical Anatomy in the 21st Century: Understanding the Possible Basis of Certain Pathologies and Clinical Symptoms

A special issue of Medicina (ISSN 1648-9144).

Deadline for manuscript submissions: 31 July 2025 | Viewed by 1983

Special Issue Editor

Dr. Juan Sanchis-Gimeno

E-Mail Website
Guest Editor
GIAVAL Research Group, Department of Anatomy and Human Embryology, Faculty of Medicine, University of Valencia, Avda Blasco Ibanez 15, E46010 Valencia, Spain
Interests: human anatomy; cornea; spine; osteology; anatomical variations; clinical anatomy

Special Issue Information

Dear Colleagues,

Knowledge of the origin and evolution of anatomical terms could fill the recesses of our brain. What is described in the anatomical literature changes very little or not at all. By applying normal anatomy, pathological anatomy, or anatomical variants to clinical practice, we can appreciate how a basic science is very useful for clinical professionals and for disciplines which teach us how to treat different pathologies. In addition, clinical anatomy is essential for tissue biopsy as knowledge of anatomy, in both cadavers and living subjects, allows tissue biopsies to be performed with maximum precision and minimal risk for patients.

The objective of this Special Issue is that authors who conduct research in surgical and/or pathological anatomy, normal anatomy, radiological anatomy, orthopedics, or about anatomical variants and congenital defects, can present their research to promote knowledge to clinicians who are unaware of it or are in training. In addition, in this Special Issue, we also promote the reverse situation: we encourage clinicians to present their anatomical findings in patients to increase the knowledge of anatomists. This Special Issue may address any region or structure of the body, giving it a wide research scope.

We invite colleagues around the world to report their original research articles, systematic reviews, meta-analyses, and narrative reviews, featuring dissection studies with findings relevant to pathology bases, osteology articles related to clinical symptoms and/or pathologies, and geometric morphometrics and shape analysis articles and imaging studies, in order to further the relationship between anatomy and clinical science.

Dr. Juan Sanchis-Gimeno
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • clinical anatomy
  • translational anatomy
  • anatomical variations
  • congenital defects
  • anatomy learning
  • surgical anatomy
  • radiological anatomy

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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15 pages, 9881 KiB  
Article
Evaluation of Sacroiliac Joint Shape in Women with Ankylosing Spondylitis According to Mode of Birth Delivery: A Retrospective Study
by Sakine Rahimli Ocakoglu, Alper Vatansever, Zeliha Atak, Nurefsan Yanardag, Belkis Nihan Coskun, Sinem Akselim and Gokhan Ocakoglu
Medicina 2025, 61(1), 39; https://doi.org/10.3390/medicina61010039 - 30 Dec 2024
Viewed by 1354
Abstract
Background and Objectives: Ankylosing spondylitis (AS) is a chronic progressive inflammatory process of the axial skeleton and sacroiliac joints (SIJ). Symptoms typically appear between the ages of 20 and 40, although there are also cases of juvenile-onset AS. This suggests that most [...] Read more.
Background and Objectives: Ankylosing spondylitis (AS) is a chronic progressive inflammatory process of the axial skeleton and sacroiliac joints (SIJ). Symptoms typically appear between the ages of 20 and 40, although there are also cases of juvenile-onset AS. This suggests that most patients with AS are of reproductive age at the time of diagnosis. The study aimed to identify differences in the shape of the sacroiliac joint depending on the type of birth (vaginal delivery (V/D) and the cesarean section(C/S) in patients with ankylosing spondylitis. Materials and Methods: On pelvis X-ray images of women n = 36 with AS and n = 34 in the control group, 12 landmarks were marked, and differences in SIJ shape between the study groups were assessed using generalized Procrustes Analysis. Results: The results showed that the anterior point of the SIJ had an enlarged shape in the V/D group compared with the C/S group, even in the control group. There was a difference between the mean right and left SIJ shapes of the AS group patients with V/D and the controls with C/S (p = 0.007 and p < 0.001). The superior part of the right SIJ tended to be enlarged in V/D-delivered AS patients, compared to the C/S control group. On the left side, the middle region of the SIJ was statistically enlarged in AS patients with V/D compared to the healthy C/S group. Conclusions: This study demonstrates that vaginal delivery is associated with increased sacroiliac joint (SIJ) enlargement in both healthy individuals and those with ankylosing spondylitis (AS). Our findings suggest that delivery type independently influences SIJ morphology, and cesarean section (C/S) may serve as a protective procedure for preserving SIJ shape in AS patients. These results underline the importance of individualized obstetric planning for AS patients to mitigate potential risks to SIJ morphology. Full article
(This article belongs to the Special Issue Clinical Anatomy in the 21st Century: Understanding the Possible Basis of Certain Pathologies and Clinical Symptoms)
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28 pages, 5728 KiB  
Systematic Review
Anatomical Variants in Pancreatic Irrigation and Their Clinical Considerations for the Pancreatic Approach and Surrounding Structures: A Systematic Review with Meta-Analysis
by Juan José Valenzuela-Fuenzalida, Camila Ignacia Núñez-Castro, Valeria Belén Morán-Durán, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandra Suazo-Santibáñez, Alvaro Becerra-Farfan, Gustavo Oyanedel-Amaro, Alejandro Bruna-Mejias, Guinevere Granite, Daniel Casanova-Martinez and Juan Sanchis-Gimeno
Medicina 2025, 61(4), 666; https://doi.org/10.3390/medicina61040666 - 4 Apr 2025
Viewed by 269
Abstract
Background and Objectives: The pancreas receives blood through a complex network of multiple branches, primarily originating from the celiac trunk (CeT) and the superior mesenteric artery (SMA). This blood supply is structured into three main arterial groups, each serving different regions of [...] Read more.
Background and Objectives: The pancreas receives blood through a complex network of multiple branches, primarily originating from the celiac trunk (CeT) and the superior mesenteric artery (SMA). This blood supply is structured into three main arterial groups, each serving different regions of the pancreas to effectively support its endocrine and exocrine functions. Materials and Methods: The databases Medline, Scopus, Web of Science, Google Scholar, Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Latin American and the Caribbean Literature in Health Sciences (LILACS) were searched until January 2025. Methodological quality was evaluated using an assurance tool for anatomical studies (AQUA). Pooled prevalence was estimated using a random effects model. Results: A total of sixteen studies met the established selection criteria in this study for meta-analysis. Pancreatic irrigation variants presented a prevalence of 11.2% (CI: 7–14%) and a heterogeneity of 88.2%. The other studies were analyzed by subgroups, showing statistically significant differences in the following subgroups: (1) sample type—a larger sample of images analyzed in the included studies (p = 0.312), which did not show statistically significant differences; (2) geographical region (p = 0.041), which showed a greater presence in the Asian population studied, and this was statistically significant; and (3) sex (male or female) (p = 0.12), where there were no statistically significant differences. Conclusions: The discovery of variations in pancreatic irrigation is common due to the numerous blood vessels involved in supplying this vital organ. Understanding different vascular patterns (such as those from the splenic and mesenteric arteries) is crucial for surgical interventions on the pancreas. For transplant patients, a thorough vascular analysis of both the donor and recipient is essential. Variations can impact blood flow and compatibility, potentially leading to transplant rejection if not addressed. To enhance outcomes, it is recommended to develop more accurate imaging tools for pre-surgical analysis, necessitating ongoing research in this area. Full article
(This article belongs to the Special Issue Clinical Anatomy in the 21st Century: Understanding the Possible Basis of Certain Pathologies and Clinical Symptoms)
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