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  • Review
  • Open Access
74 Citations
34,279 Views
29 Pages

6 September 2023

Achieving synchronization between the central and peripheral body clocks is essential for ensuring optimal metabolic function. Meal timing is an emerging field of research that investigates the influence of eating patterns on our circadian rhythm, me...

  • Article
  • Open Access
6 Citations
25,755 Views
16 Pages

Wearable Light Loggers in Field Conditions: Corneal Light Characteristics, User Compliance, and Acceptance

  • Oliver Stefani,
  • Reto Marek,
  • Jürg Schwarz,
  • Sina Plate,
  • Johannes Zauner and
  • Björn Schrader

25 October 2024

Understanding user challenges with light dosimeters is crucial for designing more acceptable devices and advancing light exposure research. We systematically evaluated the usability and acceptability of a light dosimeter (lido) with 29 participants w...

  • Review
  • Open Access
27 Citations
22,313 Views
19 Pages

The Devastating Effects of Sleep Deprivation on Memory: Lessons from Rodent Models

  • Pinqiu Chen,
  • Weikang Ban,
  • Wenyan Wang,
  • Yuyang You and
  • Zhihong Yang

In this narrative review article, we discuss the role of sleep deprivation (SD) in memory processing in rodent models. Numerous studies have examined the effects of SD on memory, with the majority showing that sleep disorders negatively affect memory...

  • Article
  • Open Access
1 Citations
17,400 Views
12 Pages

23 October 2023

Humans have a circadian rhythm for which the period varies among individuals. In the present study, we investigated the amount of natural phase delay of circadian rhythms after spending a day under dim light (Day 1 to Day 2) and the amount of phase a...

  • Article
  • Open Access
8 Citations
16,750 Views
14 Pages

Association of Meal Timing with Sleep Quality and Anxiety According to Chronotype: A Study of University Students

  • Cristina Souza da Silva Luz,
  • Ana Elizabeth Teixeira Pimentel da Fonseca,
  • Jefferson Souza Santos,
  • John Fontenele Araujo,
  • Leandro Lourenção Duarte and
  • Claudia Roberta de Castro Moreno

There are several determinants of mental health symptoms, ranging from individual characteristics to social factors. Consistent with patterns in the general population, students with evening characteristics tend to exhibit more anxiety symptoms and p...

  • Review
  • Open Access
2 Citations
16,429 Views
12 Pages

Traumatic brain injury (TBI) profoundly affects sleep, mood, and fatigue, impeding daily functioning and recovery. This systematic review evaluates the efficacy of morning shorter wavelength lighting in the visible (blue) range and broad-spectrum or...

  • Review
  • Open Access
11 Citations
15,590 Views
27 Pages

Traumatic Brain Injury, Sleep, and Melatonin—Intrinsic Changes with Therapeutic Potential

  • Allen Bell,
  • Bryson Hewins,
  • Courtney Bishop,
  • Amanda Fortin,
  • Jonathan Wang,
  • Jennifer L. Creamer,
  • Jacob Collen and
  • J. Kent Werner

Traumatic brain injury (TBI) is one of the most prevalent causes of morbidity in the United States and is associated with numerous chronic sequelae long after the point of injury. One of the most common long-term complaints in patients with TBI is sl...

  • Systematic Review
  • Open Access
28 Citations
15,116 Views
15 Pages

Effects on Sleep Quality of Physical Exercise Programs in Older Adults: A Systematic Review and Meta-Analysis

  • Lilian Solis-Navarro,
  • Olga Masot,
  • Rodrigo Torres-Castro,
  • Matías Otto-Yáñez,
  • Carles Fernández-Jané,
  • Mireia Solà-Madurell,
  • Andrea Coda,
  • Erika Cyrus-Barker,
  • Mercè Sitjà-Rabert and
  • Laura Mónica Pérez

Background: Given the beneficial effects of exercise in different populations and the close relationship between healthy ageing and sleep quality, our objective was to determine if physical exercise delivered through a structured program improves sle...

  • Review
  • Open Access
26 Citations
14,183 Views
25 Pages

Light use is rising steeply, mainly because of the advent of light-emitting diode (LED) devices. LEDs are frequently blue-enriched light sources and may have different impacts on the non-image forming (NIF) system, which is maximally sensitive to blu...

  • Review
  • Open Access
8 Citations
13,354 Views
14 Pages

Circadian Regulation for Optimizing Sport and Exercise Performance

  • Garrett R. Augsburger,
  • Eric J. Sobolewski,
  • Guillermo Escalante and
  • Austin J. Graybeal

This narrative review explores the intricate relationship between circadian regulation and exercise performance, emphasizing the importance of aligning training strategies with the body’s natural physiological fluctuations. The three key mechan...

  • Article
  • Open Access
6 Citations
13,094 Views
16 Pages

Bright Light Therapy for Major Depressive Disorder in Adolescent Outpatients: A Preliminary Study

  • Rachel Ballard,
  • John T. Parkhurst,
  • Lisa K. Gadek,
  • Kelsey M. Julian,
  • Amy Yang,
  • Lauren N. Pasetes,
  • Namni Goel and
  • Dorothy K. Sit

Background: Bright light therapy (BLT) has not been well-studied in adolescents with major depressive disorder, particularly in outpatient settings. Methods: We conducted an 8-week clinical trial of BLT in adolescents recruited from a primary care pr...

  • Article
  • Open Access
5 Citations
12,734 Views
16 Pages

Effectiveness of Enriched Milk with Ashwagandha Extract and Tryptophan for Improving Subjective Sleep Quality in Adults with Sleep Problems: A Randomized Double-Blind Controlled Trial

  • Silvia Pérez-Piñero,
  • Juan Carlos Muñoz-Carrillo,
  • Jon Echepare-Taberna,
  • Macarena Muñoz-Cámara,
  • Cristina Herrera-Fernández,
  • Vicente Ávila-Gandía,
  • María Heres Fernández Ladreda,
  • Javier Menéndez Martínez and
  • Francisco Javier López-Román

A randomized, double-blind and controlled study was conducted to assess the effectiveness of the intake of 250 mL of lactose-free skimmed milk enriched with ashwagandha (Withania somnifera) alone or combined with tryptophan vs. non-enriched milk...

  • Systematic Review
  • Open Access
15 Citations
11,829 Views
23 Pages

Microbiota Composition and Probiotics Supplementations on Sleep Quality—A Systematic Review and Meta-Analysis

  • Daniele Santi,
  • Valentina Debbi,
  • Francesco Costantino,
  • Giorgia Spaggiari,
  • Manuela Simoni,
  • Carla Greco and
  • Livio Casarini

13 December 2023

The gut microbiota (GM) plays a crucial role in human health. The bidirectional interaction between GM and the central nervous system may occur via the microbiota–gut–brain axis, possibly regulating the sleep/wake cycle. Recent reports hi...

  • Article
  • Open Access
3 Citations
11,488 Views
14 Pages

Circadian Rhythms, Regular Exercise, and Cognitive Performance in Morning-Trained Dancers

  • Mariana Marchesano,
  • Alejandra Carboni,
  • Bettina Tassino and
  • Ana Silva

Time-of-day and individual circadian variability influence cognitive performance, with later chronotypes being most compromised earlier in the day. On the other hand, moderate-intensity exercise has been shown to enhance cognitive function. We sought...

  • Review
  • Open Access
26 Citations
11,037 Views
17 Pages

The Burden of Comorbidities in Obstructive Sleep Apnea and the Pathophysiologic Mechanisms and Effects of CPAP

  • Victoria Sircu,
  • Silvia-Iaroslava Colesnic,
  • Serghei Covantsev,
  • Olga Corlateanu,
  • Anna Sukhotko,
  • Cristian Popovici and
  • Alexandru Corlateanu

Micro-arousals and the repeated desaturation of oxyhemoglobin, which are typical in obstructive sleep apnea syndrome (OSAS), have adverse effects on the health of patients, leading to a wide range of complications such as cardiovascular (arterial hyp...

  • Article
  • Open Access
2 Citations
10,825 Views
20 Pages

A Comprehensive Assessment of Bedtime Routines and Strategies to Aid Sleep Onset in College Students: A Web-Based Survey

  • Debora Meneo,
  • Sara Curati,
  • Paolo Maria Russo,
  • Monica Martoni,
  • Francesca Gelfo and
  • Chiara Baglioni

College students often experience sleep–wake alterations. Different factors can contribute to insomnia symptoms in this population. The present study aims at investigating pre-sleep behaviours and strategies used to aid sleep onset in young col...

  • Review
  • Open Access
8 Citations
10,689 Views
22 Pages

Substance use disorder is a major global health concern, with a high prevalence among adolescents and young adults. The most common substances of abuse include alcohol, marijuana, cocaine, nicotine, and opiates. Evidence suggests that a mismatch betw...

  • Article
  • Open Access
3 Citations
10,483 Views
14 Pages

On the Efficacy of a CBT-I-Based Online Program for Sleep Problems: A Randomized Controlled Trial

  • Esther-Sevil Eigl,
  • Theresa Hauser,
  • Pavlos I. Topalidis and
  • Manuel Schabus

There is an urgent need for easily accessible treatment options for sleep problems to reduce the current treatment gap in receiving cognitive behavioral therapy for insomnia (CBT-I). Using a randomized controlled trial, we evaluated the efficacy of a...

  • Review
  • Open Access
9 Citations
9,583 Views
21 Pages

Optimizing Chronotherapy in Psychiatric Care: The Impact of Circadian Rhythms on Medication Timing and Efficacy

  • Cezar-Ivan Colita,
  • Dirk M. Hermann,
  • Madalina Filfan,
  • Daniela Colita,
  • Thorsten R. Doepnner,
  • Oana Tica,
  • Daniela Glavan and
  • Aurel Popa-Wagner

5 November 2024

In many medical settings, medications are typically administered in the morning or evening, aligning with patients’ daily routines. This practice does not stem from chronotherapy, which involves scheduling drug administration to enhance its eff...

  • Article
  • Open Access
6 Citations
9,511 Views
12 Pages

Effects of Vortioxetine on Sleep Architecture of Adolescents with Major Depressive Disorder

  • Zuzana Mlyncekova,
  • Peter Hutka,
  • Zuzana Visnovcova,
  • Nikola Ferencova,
  • Veronika Kovacova,
  • Andrea Macejova,
  • Ingrid Tonhajzerova and
  • Igor Ondrejka

24 October 2023

The relationship between depression and insomnia is bidirectional and both conditions need to be treated adequately, especially in a vulnerable neurodevelopmental stage of adolescence. This study aimed to evaluate the effects of antidepressant treatm...

  • Article
  • Open Access
1 Citations
8,559 Views
17 Pages

The Efficacy of a Multimodal Bedroom-Based ‘Smart’ Alarm System on Mitigating the Effects of Sleep Inertia

  • Carolina Campanella,
  • Kunjoon Byun,
  • Araliya Senerat,
  • Linhao Li,
  • Rongpeng Zhang,
  • Sara Aristizabal,
  • Paige Porter and
  • Brent Bauer

Previous work has demonstrated the modest impact of environmental interventions that manipulate lighting, sound, or temperature on sleep inertia symptoms. The current study sought to expand on previous work and measure the impact of a multimodal inte...

  • Article
  • Open Access
4 Citations
8,556 Views
16 Pages

Evaluation of Sleep Behavior and the Use of Sleep Aids among Adults Living in Saudi Arabia: A Cross-Sectional Study

  • Ahmed Aldhafiri,
  • Nawaf Almutairi,
  • Mohammed Alharbi,
  • Abdullah Aloufi,
  • Abdulaziz Hakeem,
  • Abdulmalik Kattan and
  • Fahad Alzahrani

11 September 2023

A negative attitude toward sleep has greatly affected sleep habits. In addition to contributing to physical and metabolic disorders, poor sleep quality may cause emotional disturbances. This study aimed to measure sleep behavior and factors contribut...

  • Brief Report
  • Open Access
1 Citations
8,435 Views
10 Pages

Time of Day and Sleep Deprivation Effects on Risky Decision Making

  • Noelia Ruiz-Herrera,
  • Mia Friedman,
  • Melissa A. St. Hilaire,
  • Arturo Arrona-Palacios,
  • Charles A. Czeisler and
  • Jeanne F. Duffy

Previous research has revealed that daily variations in human neurobehavioral functions are driven in part by the endogenous circadian system. The objective of this study was to explore whether there exists a circadian influence on performance regard...

  • Brief Report
  • Open Access
2 Citations
8,430 Views
8 Pages

The main aim of this study was to explore how melatonin onset timing and phase angle to bedtime in healthy older adults are impacted by prior light exposure. A total of 13 healthy older (ages 56–74) individuals were studied on two successive ev...

  • Review
  • Open Access
3 Citations
8,429 Views
20 Pages

In humans, the master circadian clock, present in the suprachiasmatic nucleus, plays an important role in controlling life-sustaining functions. The development of the circadian clock begins in the fetal period and is almost completed during infancy...

  • Article
  • Open Access
3 Citations
8,393 Views
17 Pages

Sleep Fragmentation Modulates the Neurophysiological Correlates of Cognitive Fatigue

  • Oumaïma Benkirane,
  • Peter Simor,
  • Olivier Mairesse and
  • Philippe Peigneux

22 October 2024

Cognitive fatigue (CF) is a critical factor affecting performance and well-being. It can be altered in suboptimal sleep quality conditions, e.g., in patients suffering from obstructive sleep apnea who experience both intermittent hypoxia and sleep fr...

  • Review
  • Open Access
16 Citations
8,363 Views
18 Pages

The Relationship between Sleep, Chronotype, and Dental Caries—A Narrative Review

  • Anamaria Kurtović,
  • Jasminka Talapko,
  • Sanja Bekić and
  • Ivana Škrlec

This article provides an overview of how sleep and circadian rhythm disturbances mutually influence the occurrence of dental caries and how it is possible to reduce the risk of circadian rhythm disturbances, sleep, and associated adverse effects. Den...

  • Communication
  • Open Access
16 Citations
7,596 Views
16 Pages

1 November 2023

It is well known that variations in light exposure during the day affect light sensitivity in the evening. More daylight reduces sensitivity, and less daylight increases it. On average days, we spend less time outdoors in winter and receive far less...

  • Article
  • Open Access
6 Citations
7,069 Views
16 Pages

Predicting Sleep Quality through Biofeedback: A Machine Learning Approach Using Heart Rate Variability and Skin Temperature

  • Andrea Di Credico,
  • David Perpetuini,
  • Pascal Izzicupo,
  • Giulia Gaggi,
  • Nicola Mammarella,
  • Alberto Di Domenico,
  • Rocco Palumbo,
  • Pasquale La Malva,
  • Daniela Cardone and
  • Angela Di Baldassarre
  • + 2 authors

Sleep quality (SQ) is a crucial aspect of overall health. Poor sleep quality may cause cognitive impairment, mood disturbances, and an increased risk of chronic diseases. Therefore, assessing sleep quality helps identify individuals at risk and devel...

  • Article
  • Open Access
7 Citations
6,556 Views
28 Pages

23 December 2024

Continued solicitation of cognitive resources eventually leads to cognitive fatigue (CF), i.e., a decrease in cognitive efficiency that develops during sustained cognitive demands in conditions of constrained processing time, independently of sleepin...

  • Article
  • Open Access
3 Citations
6,530 Views
21 Pages

The Impact of Sleep on Haematological Parameters in Firefighters

  • Sara Alves,
  • Francisca Silva,
  • Filipa Esteves,
  • Solange Costa,
  • Klara Slezakova,
  • Maria Alves,
  • Maria Pereira,
  • João Teixeira,
  • Simone Morais and
  • Josiana Vaz
  • + 2 authors

Sleep is a vital process that impacts biological functions such as cell renewal, bone regeneration, and immune system support. Disrupted sleep can interrupt erythropoiesis, leading to fewer red blood cells, reduced haemoglobin concentration, and decr...

  • Review
  • Open Access
6 Citations
6,515 Views
11 Pages

Sleep Disturbances in At-Risk Mental States and First Episode of Psychosis: A Narrative Review on Interventions

  • Lorena Marin,
  • Armand Guàrdia,
  • Alexandre González-Rodríguez,
  • José Haba-Rubio,
  • Mentxu Natividad,
  • Elena Bosch,
  • Noelia Domínguez and
  • José Antonio Monreal

Sleep disturbances are a common yet often overlooked symptom of psychosis that can drastically affect the quality of life and well-being of those living with the condition. Sleep disorders are common in people diagnosed with schizophrenia and have si...

  • Article
  • Open Access
6,498 Views
16 Pages

Impact of Varying Sleep Pressure on Daytime Sleep Propensity in Healthy Young and Older Adults

  • Stella de Haan,
  • Marine Dourte,
  • Michele Deantoni,
  • Mathilde Reyt,
  • Marion Baillet,
  • Christian Berthomier,
  • Vincenzo Muto,
  • Gregory Hammad,
  • Christian Cajochen and
  • Svetlana Postnova
  • + 3 authors

Fixed sleep schedules with an 8 h time in bed (TIB) are used to ensure participants are well-rested before laboratory studies. However, such schedules may lead to cumulative excess wakefulness in young individuals. Effects on older individuals are un...

  • Article
  • Open Access
16 Citations
6,346 Views
15 Pages

Causal Effects of Gut Microbiota on Sleep-Related Phenotypes: A Two-Sample Mendelian Randomization Study

  • Min Yue,
  • Chuandi Jin,
  • Xin Jiang,
  • Xinxin Xue,
  • Nan Wu,
  • Ziyun Li and
  • Lei Zhang

12 September 2023

Increasing evidence suggests a correlation between changes in the composition of gut microbiota and sleep-related phenotypes. However, it remains uncertain whether these associations indicate a causal relationship. The genome-wide association study s...

  • Article
  • Open Access
5 Citations
6,334 Views
18 Pages

The Impact of DAZZEON αSleep® Far-Infrared Blanket on Sleep, Blood Pressure, Vascular Health, Muscle Function, Inflammation, and Fatigue

  • Mon-Chien Lee,
  • Chin-Shan Ho,
  • Yi-Ju Hsu,
  • Nai-Wen Kan,
  • Chen-Yin Fei,
  • Hung-Jen Yang and
  • Chi-Chang Huang

4 September 2024

The application of far-infrared blankets has shown certain benefits in health promotion and therapy, such as improving blood circulation and alleviating muscle pain. However, the effects of such blankets on increasing deep sleep, reducing blood press...

  • Review
  • Open Access
20 Citations
6,316 Views
16 Pages

The biological clock is a molecular oscillator that generates a 24-hour rhythm in accordance with the earth’s rotation. Physiological functions and pathophysiological processes such as inflammatory bowel diseases (IBD) are closely linked to the...

  • Conference Report
  • Open Access
2 Citations
6,209 Views
62 Pages

The Society for Light Treatment and Biological Rhythms (SLTBR) held this year’s annual meeting at the Ecole Polytechnique Fédérale (EPFL) in Lausanne, Switzerland from 30 May to 1 June in conjunction with the Day Light Academy (DL...

  • Article
  • Open Access
4 Citations
6,171 Views
13 Pages

Insomnia and Migraine: A Missed Call?

  • Angelo Torrente,
  • Lavinia Vassallo,
  • Paolo Alonge,
  • Laura Pilati,
  • Andrea Gagliardo,
  • Davide Ventimiglia,
  • Antonino Lupica,
  • Vincenzo Di Stefano,
  • Cecilia Camarda and
  • Filippo Brighina

Migraine is one of the most prevalent and disabling neurological conditions, presenting episodes of throbbing headache that limit activities of daily living. Several factors may influence migraine frequency, such as lifestyle or alcohol consumption....

  • Article
  • Open Access
17 Citations
6,134 Views
15 Pages

Shift Happens: Emergency Physician Perspectives on Fatigue and Shift Work

  • Zachary Klinefelter,
  • Emily L. Hirsh,
  • Thomas W. Britt,
  • Caroline L. George,
  • Margaret Sulzbach and
  • Lauren A. Fowler

Research has shown that shiftworkers experience poor sleep and high levels of fatigue. Although considerable research has been performed on fatigue within many shift-work occupations, very little has been done with emergency physicians (EPs). This qu...

  • Article
  • Open Access
4 Citations
6,099 Views
10 Pages

Chronotype reflects the morningness–eveningness preference over a 24 h period. Significant data indicate meaningful differences between evening types (ETs) and morning types (MTs) in behavior, personality traits, health, and well-being. This st...

  • Article
  • Open Access
2 Citations
6,016 Views
16 Pages

Sleep Efficiency and Sleep Onset Latency in One Saskatchewan First Nation

  • Chandima P. Karunanayake,
  • Punam Pahwa,
  • Shelley Kirychuk,
  • Mark Fenton,
  • Vivian R. Ramsden,
  • Jeremy Seeseequasis,
  • Warren Seesequasis,
  • Robert Skomro,
  • Donna C. Rennie and
  • James A. Dosman
  • + 5 authors

Background: Sleep efficiency and sleep onset latency are two measures that can be used to assess sleep quality. Factors that are related to sleep quality include age, sex, sociodemographic factors, and physical and mental health status. This study ex...

  • Review
  • Open Access
3 Citations
5,963 Views
24 Pages

Sleep is an essential part of everyday life and disturbed sleep can produce numerous deleterious effects on the body. An especially prevalent and detrimental subset of sleep disturbances are sleep disturbances that occur in patients during the postop...

  • Review
  • Open Access
8 Citations
5,850 Views
11 Pages

Sleep Quality and Medication Adherence in Older Adults: A Systematic Review

  • Leandro Amato,
  • Noemi Giannetta,
  • Sofia Taborri,
  • Sara Dionisi,
  • Nicolò Panattoni,
  • Emanuele Di Simone,
  • Aurora De Leo,
  • Gloria Liquori,
  • Giovanni Battista Orsi and
  • Marco Di Muzio
  • + 1 author

3 September 2024

Sleep quality significantly impacts individuals’ overall health, especially in older adults. Older adults often face comorbid conditions, polypharmacy (the intake of five or more medications per day), and medication non-adherence, which are com...

  • Article
  • Open Access
3 Citations
5,804 Views
11 Pages

The present study investigated the effect of acute sleep extension on blood pressure and microvascular vasodilation. Sleep and daily physical activity were objectively measured at home for two weeks using wrist actigraphy in 22 adults (60 ± 15...

  • Article
  • Open Access
8 Citations
5,747 Views
15 Pages

Time Spent Outdoors and Associations with Sleep, Optimism, Happiness and Health before and during the COVID-19 Pandemic in Austria

  • Simon Schamilow,
  • Isabel Santonja,
  • Jakob Weitzer,
  • Susanne Strohmaier,
  • Gerhard Klösch,
  • Stefan Seidel,
  • Eva Schernhammer and
  • Kyriaki Papantoniou

Social restriction measures (SRM) implemented during the COVID-19 pandemic led to a reduction in time spent outdoors (TSO). The aim of this study was to describe TSO and evaluate its association with sleep outcomes, optimism, happiness and health-sta...

  • Review
  • Open Access
2 Citations
5,719 Views
13 Pages

Methods for REM Sleep Density Analysis: A Scoping Review

  • Tamires Tiemi Kishi,
  • Monica Levy Andersen,
  • Ygor Matos Luciano,
  • Viviane Akemi Kakazu,
  • Sergio Tufik and
  • Gabriel Natan Pires

14 December 2023

Rapid eye movements (REM) sleep density is the parameter proposed to explain the variability in the amount of eye movements during REM sleep. Alterations in REM sleep density have been proposed as a screening criterion for individuals with depression...

  • Article
  • Open Access
2 Citations
5,610 Views
19 Pages

Identifying Risk and Protective Factors for Shift Work Sleep Disorder: Insights from UK Biobank Night Shift Workers

  • Jürgen Degenfellner,
  • Susanne Strohmaier,
  • Magdalena Zebrowska,
  • Ingvild Saksvik-Lehouillier and
  • Eva Schernhammer

Shift Work Sleep Disorder (SWSD) is a significant and highly prevalent condition affecting up to 48% of individuals with irregular work schedules. The diagnostic criteria for SWSD include persistent insomnia or sleepiness in relation to shift work, n...

  • Article
  • Open Access
5 Citations
5,364 Views
22 Pages

Deletion of the Circadian Clock Gene Per2 in the Whole Body, but Not in Neurons or Astroglia, Affects Sleep in Response to Sleep Deprivation

  • Katrin S. Wendrich,
  • Hamid Azimi,
  • Jürgen A. Ripperger,
  • Yann Ravussin,
  • Gregor Rainer and
  • Urs Albrecht

The sleep–wake cycle is a highly regulated behavior in which a circadian clock times sleep and waking, whereas a homeostatic process controls sleep need. Both the clock and the sleep homeostat interact, but to what extent they influence each ot...

  • Article
  • Open Access
7 Citations
5,299 Views
13 Pages

Disruption of Circadian Sleep/Wake Rhythms in Infants May Herald Future Development of Autism Spectrum Disorder

  • Teruhisa Miike,
  • Kentaro Oniki,
  • Makiko Toyoura,
  • Shiro Tonooka,
  • Seiki Tajima,
  • Jun Kinoshita,
  • Junji Saruwatari and
  • Yukuo Konishi

We investigated whether the abnormal rhythms in infants are related to the future development of autism spectrum disorder (ASD), using a questionnaire from September to October 2016. The parents of 160 children with ASD (male, n = 123; female, n = 37...

  • Article
  • Open Access
4 Citations
5,255 Views
15 Pages

Power Analysis for Human Melatonin Suppression Experiments

  • Manuel Spitschan,
  • Parisa Vidafar,
  • Sean W. Cain,
  • Andrew J. K. Phillips and
  • Ben C. Lambert

26 February 2024

In humans, the nocturnal secretion of melatonin by the pineal gland is suppressed by ocular exposure to light. In the laboratory, melatonin suppression is a biomarker for this neuroendocrine pathway. Recent work has found that individuals differ subs...

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Clocks & Sleep - ISSN 2624-5175