Proceedings, Volume 11, Issue 1

Cardiovascular diseases are the major cause of mortality, with 17.9 million deaths/year worldwide and 3.9 million deaths/year in Europe, representing a cost to the EU economy of €210 billion/year [1,2]. [...]

DNA methylation is the most well-known epigenetic modification of DNA. This epigenetic mark is crucial in controlling gene expression profiles, maintaining cellular identity, genomic imprinting and X-chromosome inactivation. Furthermore, DNA methylat...

Ageing is inextricably linked to a deterioration of the musculoskeletal system. This suggests factors governing lifespan might also impact the maintenance of skeletal integrity throughout life. The Oxford Musculoskeletal Ageing group studies the caus...

Skeletal muscle has been recognized as an endocrine tissue that releases appreciable amounts of circulating proteins, called myokines. [...]

Ageing is a complex process affected by both genetic and environmental factors, characterized by a gradual failure of functionality, reduced stress response and resistance, leading to enhanced probability for age-related diseases and mortality. Durin...

Whey proteins are highly valued food ingredients. This study examines the health benefits to muscle cells of six individual whey peptides known to cross the intestinal barrier. Results indicate that peptides KVPQ, NLPPL, VAGT, VGIN and PVPQ protect u...

Oxidative reactions are vital but also cause important stresses and cellular damages resulting in cancers, cardiovascular or neurodegenerative diseases. Antioxidant secondary metabolites from plant can be mobilized for the cell defense and their mai...

Several of the peroxisomal neurodegenerative disorders are the consequence of a specific deficiency of an enzyme or a transporter involved in peroxisomal beta-oxidation of very long chain fatty acids [1,2]. [...]

There are many complicated pathogenic diseases caused by cell genes that are incorrectly expressed or not sufficiently active for normal cell functioning [...]

Hydroquinone (HQ) is a phenolic metabolite of benzene, which is used as a skin whitener. Insects synthesize this natural compound as a deterrent and mushrooms as a toxin. Pro-apoptotic effects of HQ were previously documented on various cancer cell t...