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Proceedings 2019, 11(1), 6; https://doi.org/10.3390/proceedings2019011006

Regulation of Cellular Redox Homeostasis by (–)-Epicatechin and Cocoa Extracts—A Pilot Study

1
University of Belgrade, Faculty of Pharmacy, Vojvode Stepe 450, 11221 Belgrade, Serbia
2
University of Gdansk, Faculty of Chemistry, Narutowicza 11/12, 80-233 Gdansk, Poland
*
Author to whom correspondence should be addressed.
Presented at Natural Products and the Hallmarks of Chronic Diseases—COST Action 16112, Luxembourg, 25–27 March 2019.
Published: 16 April 2019
PDF [497 KB, uploaded 16 April 2019]

Abstract

Cocoa polyphenols play an important role in protection against diseases in which oxidative stress is implicated as a causal or contributing factor. The main aim of this study was to elucidate the influence of different cocoa extracts and main cocoa bioactive compound (–)-epicatechin on cell growth and support of antioxidant cellular barrier in colon adenocarcinoma cell line model (HT29). Results show that the tested cocoa bioactivity results from concerted interactions between epicatechin and other components. Hence, cocoa is a very good example which supports the food synergy concept that is attracting growing interest.
Keywords: cellular antioxidant activity; cocoa extract; (–)-epicatechin; food synergy cellular antioxidant activity; cocoa extract; (–)-epicatechin; food synergy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Todorovic, V.; Baranowska, M.; Sobajic, S.; Bartoszek, A. Regulation of Cellular Redox Homeostasis by (–)-Epicatechin and Cocoa Extracts—A Pilot Study. Proceedings 2019, 11, 6.

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