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Open AccessProceedings

Regulation of Cellular Redox Homeostasis by (–)-Epicatechin and Cocoa Extracts—A Pilot Study

1
Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia
2
Faculty of Chemistry, University of Gdansk, Narutowicza 11/12, 80-233 Gdansk, Poland
*
Author to whom correspondence should be addressed.
Presented at Natural Products and the Hallmarks of Chronic Diseases—COST Action 16112, Luxembourg, 25–27 March 2019.
Proceedings 2019, 11(1), 6; https://doi.org/10.3390/proceedings2019011006
Published: 16 April 2019
(This article belongs to the Proceedings of CA16112 - Luxemburg 2019)
Cocoa polyphenols play an important role in protection against diseases in which oxidative stress is implicated as a causal or contributing factor. The main aim of this study was to elucidate the influence of different cocoa extracts and main cocoa bioactive compound (–)-epicatechin on cell growth and support of antioxidant cellular barrier in colon adenocarcinoma cell line model (HT29). Results show that the tested cocoa bioactivity results from concerted interactions between epicatechin and other components. Hence, cocoa is a very good example which supports the food synergy concept that is attracting growing interest.
Keywords: cellular antioxidant activity; cocoa extract; (–)-epicatechin; food synergy cellular antioxidant activity; cocoa extract; (–)-epicatechin; food synergy
MDPI and ACS Style

Todorovic, V.; Baranowska, M.; Sobajic, S.; Bartoszek, A. Regulation of Cellular Redox Homeostasis by (–)-Epicatechin and Cocoa Extracts—A Pilot Study. Proceedings 2019, 11, 6.

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