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Comparison of Redox Properties of Flavonoid Aglycones and Corresponding Glycosides and Their Mixtures in the Cellular Model

1
Department of Food Chemistry, Technology and Biotechnology, Gdansk University of Technology, 80-233 Gdansk, Poland
2
Department of Analytical Chemistry, Gdansk University of Technology, 80-233 Gdansk, Poland
*
Author to whom correspondence should be addressed.
Presented at Natural Products and the Hallmarks of Chronic Diseases-COST Action 16112, Luxemburg, 25–27 March 2019.
Proceedings 2019, 11(1), 25; https://doi.org/10.3390/proceedings2019011025
Published: 18 April 2019
PDF [373 KB, uploaded 18 April 2019]

Abstract

Flavonoids are polyphenolic compounds commonly found in plants. As dietary components, they have been shown to exhibit numerous pro-health properties that are believed to be associated with their antioxidant effects. In this study, the antioxidant activity of four flavonoid compounds was determined by cellular antioxidant activity assay using HT29 cells as a model of the alimentary tract. The strongest impact on cellular redox status was observed for aglycones which acted as both antioxidants (quercetin) and prooxidants (naringenin). Interestingly, mixtures of tested compounds displayed only antioxidative properties.
Keywords: cellular antioxidant activity; redox properties; quercetin; rutin; naringin; naringenin cellular antioxidant activity; redox properties; quercetin; rutin; naringin; naringenin
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Koziara, Z.; Baranowska, M.; Bartoszek, A.; Namieśnik, J. Comparison of Redox Properties of Flavonoid Aglycones and Corresponding Glycosides and Their Mixtures in the Cellular Model. Proceedings 2019, 11, 25.

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