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Journal of Fungi, Volume 11, Issue 6

June 2025 - 64 articles

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Cover Story: Oxidative stress is a key immune defense mechanism against fungal infections such as sporotrichosis, caused by Sporothrix schenckii. Phagocytic cells recognize fungal PAMPs via pattern recognition receptors (PRRs), triggering immune responses including the production of reactive oxygen species (ROS) to eliminate the pathogen. However, S. schenckii evades this defense mechanism through antioxidant enzymes, cell wall modifications, melanin production, and moonlighting proteins that contribute to immune evasion and stress resistance. These strategies, combined with gene expression modulation, enable fungal survival and infection persistence. Understanding these interactions is crucial for developing effective therapies. View this paper

Articles (64)

  • Article
  • Open Access
1,167 Views
13 Pages

19 June 2025

Candidiasis is a major fungal infection worldwide, with invasive forms linked to high morbidity and mortality. The emergence of azole resistance in Candida parapsilosis causing candidemia led us to examine the epidemiology and antifungal susceptibili...

  • Brief Report
  • Open Access
859 Views
11 Pages

Assessment of Entomopathogenic Fungi Activity from the Fiocruz Amazônia Collection in Anopheles aquasalis Mosquitoes

  • Natalia Stefany Pereira,
  • Camila Fabbri,
  • Kemily Nunes Moya,
  • Ana Carolina Monteiro Ferreira,
  • Francy’s Sayara Andrade,
  • Rosa Amélia Santana,
  • Claudia Maria Ríos-Velásquez,
  • Priscila Ferreira de Aquino and
  • Stefanie Costa Pinto Lopes

18 June 2025

Malaria remains a public health issue across the world. Different methods have been analyzed to achieve this disease’s elimination, such as the vector control of Anopheles spp. Control strategies include the use of different classes of insectic...

  • Article
  • Open Access
1,075 Views
23 Pages

18 June 2025

Cordyceps militaris, a model species in the genus Cordyceps, is widely distributed globally and is known for its significant medicinal value. It has been traditionally used in Chinese medicine to enhance immunity, alleviate fatigue, and treat tumors,...

  • Article
  • Open Access
1,083 Views
17 Pages

New Therapeutic Options for Fusariosis: A Patent Review (2008–2023)

  • Izadora Dillis Faccin,
  • Túlio Máximo Salomé,
  • Gleyce Hellen de Almeida de Souza,
  • Leonardo da Costa Xavier,
  • Izabel Almeida Alves,
  • Vanessa Castro Felix Lima,
  • Fabíola Lucini,
  • Simone Simionatto and
  • Luana Rossato

18 June 2025

Fusariosis is an infection caused by the fungus Fusarium spp., which is pathogenic to both plants and humans. The disease presents several clinical manifestations and epidemiological patterns. Current treatment relies on azoles and polyenes, but incr...

  • Article
  • Open Access
1 Citations
1,155 Views
15 Pages

Histoplasmosis in Immunocompromised and Immunocompetent Patients in Guadeloupe

  • Constance Lahuna,
  • Tanguy Dequidt,
  • Pierre Postel-Vinay,
  • Sandrine Peugny,
  • Marwan Haboub,
  • Samuel Markowicz and
  • Muriel Nicolas

18 June 2025

Background: Histoplasma capsulatum is an environmentally acquired dimorphic fungus. Infection results in histoplasmosis, a clinical syndrome often underdiagnosed and that may progress to life-threatening disseminated infection not only in immuno...

  • Article
  • Open Access
2,993 Views
17 Pages

Development and Characterization of Mycelium-Based Composite Using Agro-Industrial Waste and Ganoderma lucidum as Insulating Material

  • Gustavo Jiménez-Obando,
  • Juan Sebastian Arcila,
  • Ricardo Augusto Tolosa-Correa,
  • Yenny Leandra Valencia-Cardona and
  • Sandra Montoya

17 June 2025

Mycelium-based composites (MBCs) have emerged as eco-friendly alternatives, utilizing fungal mycelium as a natural binder for agro-industrial residues. This study focuses on developing an MBC based on abundant waste in Colombia, pith Arboloco (A) (Mo...

  • Article
  • Open Access
1,673 Views
44 Pages

Hidden Treasures of Colombia’s Pacific Mangrove: New Fungal Species and Records of Macrofungi (Basidiomycota)

  • Viviana Motato-Vásquez,
  • Lina Katherine Vinasco-Diaz,
  • Jorge M. Londoño-Caicedo and
  • Ana C. Bolaños-Rojas

17 June 2025

Mangrove-associated fungi represent a diverse but understudied group of eukaryotic organisms, especially in the Neotropics. The Colombian Pacific region, with approximately 1300 km of coastline covered with 194,880 ha of mangrove forests that remain...

  • Review
  • Open Access
2 Citations
1,471 Views
36 Pages

Fungal Coculture: Unlocking the Potential for Efficient Bioconversion of Lignocellulosic Biomass

  • Rafael Icaro Matos Vieira,
  • Alencar da Silva Peixoto,
  • Antonielle Vieira Monclaro,
  • Carlos André Ornelas Ricart,
  • Edivaldo Ximenes Ferreira Filho,
  • Robert Neil Gerard Miller and
  • Taísa Godoy Gomes

17 June 2025

Microbial decomposition of persistent natural compounds such as phenolic lignin and polysaccharides in plant cell walls plays a crucial role in the global carbon cycle and underpins diverse biotechnological applications. Among microbial decomposers,...

  • Article
  • Open Access
1,234 Views
28 Pages

Exploring the Bioactive Secondary Metabolites of Two Argentine Trichoderma afroharzianum Strains

  • Rodrigo José Nunes Calumby,
  • Antonella Santone,
  • Estefanía Butassi,
  • Laura Andrea Svetaz,
  • Márcia de Souza Carvalho Melhem,
  • Sebastián Pablo Rius and
  • Valeria Alina Campos-Bermudez

17 June 2025

Trichoderma spp. produce diverse secondary metabolites with biological activity. This study explored the antimicrobial, antibiofilm, antioxidant, and cytotoxic properties of metabolites from two native Trichoderma strains, 10BR1 and UEPA AR12, isolat...

  • Article
  • Open Access
1,425 Views
11 Pages

Real-World Experience with Isavuconazole for Invasive Aspergillosis in Hematologic Patients with and Without COVID-19 in Brazil

  • Larissa Simão Gandolpho,
  • Vinicius Ponzio,
  • Marjorie Vieira Batista,
  • Ivan Leonardo Avelino França e Silva,
  • Jessica Fernandes Ramos,
  • Marcio Nucci and
  • Arnaldo Lopes Colombo

16 June 2025

(1) Background: Invasive aspergillosis is a life-threatening fungal infection, particularly in patients with hematologic malignancies. Isavuconazole, a broad-spectrum triazole, has emerged as a key treatment option, but real-world data in high-risk p...

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