2025 July - 79 articles
Root rot is one of the most serious diseases affecting Astragalus membranaceus, significantly reducing its yield and quality. This study focused on root rot in Astragalus membranaceus var. mongholicus. Pathogenic fungi were isolated and identified. T...
The fungal kingdom, with an estimated five million species, has undergone extensive diversification over the past billion years and now occupies a wide array of ecological niches from terrestrial to aquatic ecosystems. To thrive in such diverse envir...
Fusaric acid (FSA) is a mycotoxin produced by pathogenic Fusarium species that inhibits the growth of various beneficial microbes. In this study, we investigated the molecular mechanisms by which Trichoderma harzianum NJAU4742 (Th), a beneficial fung...
Culinary melon (Cucumis melo subsp. agrestis var. conomon) is widely cultivated throughout Thailand and represents an important agricultural crop. During 2023–2024, anthracnose, charcoal rot, and fruit rot caused by fungi were observed on posth...
The locoweeds Astragalus and Oxytropis in the Americas and China, as well as Swainsona in Australia, harbor swainsonine-producing endophytes responsible for “locoism” or “pea struck” syndromes in grazing animals. Demonstration...
With the rise in immunocompromised individuals and patients with immune-related comorbidities such as COVID-19, the rate of fungal infections is growing. This increase, along with the current plateau in antifungal drug development, has made understan...
Postharvest fungal diseases are a major cause of fruit spoilage and economic losses, particularly in perishable commodities like strawberries. In this study, a plant-derived Weissella paramesenteroides strain R2 was isolated from the mango fruit surf...
Pleurotus ostreatus is a mushroom species renowned for its abundant nutritional and medicinal properties. Nevertheless, the yield of its fruiting bodies has long remained at a standstill, making it arduous to achieve substantial improvements. Because...
The cellulose-binding domain and inter-domain linker play crucial roles in the degradation of crystalline cellulose by cellulases. Although significant differences exist in the degradation efficiency of cellobiohydrolase I (CBH I) derived from differ...
The potential of Trichoderma fungi as biocontrol agents has not yet been fully explored, as there is a large repertoire of inter- and intra-species variation in their phytopathogenic antagonistic effects due to different adaptations of individual Tri...
The filamentous fungal genus Aspergillus represents an industrially significant group of eukaryotic microorganisms. For nearly a century, it has been widely utilized in the production of diverse high-value products, including organic acids, industria...
Superficial fungal infections (SFIs) remain a common dermatological issue in the pediatric population, with varying prevalence across regions and age groups. This study aimed to assess the epidemiology of SFIs among children and adolescents in northe...
Ganoderma lucidum polysaccharides (GLPs) are natural compounds with a broad spectrum of biological activities. β-1,3-glucosyltransferase (GL20535) plays an important role in polysaccharide synthesis by catalyzing the transfer of UDP-glucose to e...
Tinea incognito is an incorrectly diagnosed form of fungal infection due to a changed clinical picture as a result of systemic or topical corticosteroids or even local immunomodulators. This type of skin lesion is most often located on the trunk but...
This study aims to reveal the impact mechanisms of five typical topographic habitats in the Sanjiangyuan region (sunny slope, depression, shady slope, mountain pass, and transitional zone) on the characteristics and functions of rhizosphere soil fung...
Cryptococcus neoformans is an opportunistic fungal pathogen and causative agent of cryptococcosis and cryptococcal meningitis (CM). Cryptococcal disease accounts for up to 19% of AIDS-related mortalities globally, warranting its label as a pathogen o...
Several species of Fusarium are reported to infect inflorescences of high-THC-containing cannabis (Cannabis sativa L.) plants grown in greenhouses in Canada. These include F. graminearum, F. sporotrichiodes, F. proliferatum, and, to a lesser extent,...
Aquatic fungi serve as core ecological engines in freshwater ecosystems, driving organic matter decomposition and energy flow to sustain environmental balance. Wetlands, with their distinct hydrological dynamics and nutrient-rich matrices, serve as c...
Downy mildew, caused by Plasmopara viticola, is a major threat to grapevine (Vitis vinifera) cultivation in humid climates. Restrictions on synthetic pesticides and inconsistent efficacy of current biocontrol agents, especially under rainy conditions...
The biomass allocation patterns between aboveground and belowground are an essential functional trait for plant survival under a changing environment. The effects of arbuscular mycorrhizal fungi (AMF) communities on plant biomass allocation, particul...
Rhamnose is a natural sugar found in glycoproteins and structural polysaccharides of plants, fungi, and bacteria. Its incorporation into glycoconjugates is mediated by rhamnosyltransferases (RHTs), key enzymes for biomolecular stability and function....
Trichophyton indotineae is emerging globally from its origin in India, presenting with a terbinafine resistance and causing significant clinical burden. We report herein the first four confirmed cases of T. indotineae dermatophytoses in Malaysia, whi...
The effects of potassium (K+) on yeast metabolism were documented as early as 1940. Studies proposing a mechanism for its transport started in 1950, and in 1953, a mechanism for the stimulation of fermentation was suggested. However, it was not until...
The interactions of Fusarium graminearum PG-Fg1 and its main trichothecenes with the 28 Trichoderma isolates were studied in vitro. The antagonistic effect assessed by dual-culture tests showed that Trichoderma isolates arrested the growth of PG-Fg1...
Toenail onychomycosis causes significant problems in public health and is more common among the elderly and immune-compromised populations. A previous culture-based survey of communal finely ground toenails from the east coast of Australia isolated 1...
The number of fungal infections is steadily increasing, with considerable morbidity and mortality. Additionally, antifungal resistance is a growing concern, highlighting the need to develop new treatment options. One alternative is the use of antimic...
The increasing emergence of antifungal resistance poses potential clinical challenges, particularly among immunocompromised patients with cancer at risk of invasive mold infections, but data on antifungal susceptibility trends specific to this popula...
Plant-parasitic nematodes represent a significant threat to agriculture, causing substantial economic losses worldwide. Among the biological alternatives for their control, the genus Trichoderma has emerged as a promising solution for suppressing var...
Plant–endophyte symbioses are widespread in grasslands. While symbiotic interactions often provide hosts with major fitness enhancements, the role of the endophyte Alternaria oxytropis, which produces swainsonine in locoweeds (Oxytropis and Ast...
Mycogone perniciosa is the causative agent of wet bubble disease, which induces significant losses in the production of Agaricus bisporus, indicating the high importance of the development of novel inhibitory agents. The isolation, identification, an...
Blackleg caused by a hemi-biotrophic fungus Plenodomus lingam (syn. Leptosphaeria maculans) poses a significant threat to global canola production. Changing climatic conditions further exacerbate the intensity and prevalence of blackleg epidemics. Sh...
Saccharomyces cerevisiae often undergoes strain degeneration during industrial serial subculturing, though this phenomenon remains understudied. This study first conducted strain screening and biological characterization through TTC (2,3,5-triphenylt...
Fruiting body formation in edible fungi is a critical development process for both scientific understanding and industrial cultivation, yet the underlying genetic mechanisms remain poorly elucidated. This study aimed to identify key genes regulating...
Nine chaetoglobosins (1–9) including five previously undescribed ones (1–5) were obtained from the culture broth of an endophytic fungus (Chaetomium sp. UJN-EF006) isolated from the leaves of Vaccinium bracteatum. The structures of these...
This study investigates the potential role of Acrocalymma dark septate endophytic (DSE) fungi in promoting the growth of Solanum lycopersicum (tomato). Recognized as important symbionts that enhance plant growth and resilience under stress, particula...
Sclerotinia sclerotiorum, known as a typical necrotrophic pathogenic fungus, exhibits a complex pathogenic mechanism. Research on S. sclerotiorum has primarily focused on oxalic acid, pathogenicity-related enzymes, and secreted proteins. In this stud...
Species of Talaromyces C.R. Benj. are valuable biological resources for human beings as competent producers of enzymes, antibiotics, antifungal agents and biopigments, but a comprehensive taxonomic system at the series level has not been fully provid...
The early diagnosis and treatment of mucormycosis improves outcomes and saves lives [...]
Monascus produces various bioactive compounds, including monacolin K (MK), γ-aminobutyric acid (GABA), and Monascus pigments (MPs). Studies have shown that overexpressing genes within the MK biosynthetic cluster significantly enhances MK produc...
Paracoccidioides brasiliensis is a thermally dimorphic fungal pathogen and the main etiological agent of paracoccidioidomycosis (PCM), a neglected systemic mycosis endemic in Latin America. The virulence of P. brasiliensis is closely associated with...
Malt bagasse is the primary solid waste product from the brewing process, with notable environmental implications. Due to its nutritional value, it has potential as animal feed, primarily through ensilage. Alfalfa pellets can enhance this silage by a...
The emergence of antifungal-resistant Aspergillus fumigatus (A. fumigatus) became a serious public health concern, underscoring the need for new effective antifungal agents. Here, we present a strategy based on the in situ generation of radical speci...
Fungi are the most poorly described kingdom of Eukarya. Fundamental questions about their species diversity, their distributions, and their biotic interactions remain largely unanswered, despite fungi playing important roles in the ecology and biogeo...
The complosome controls different activities in innate immune cells and epithelial cells; however, its role in the response of VECs to Candida remains untested. In this in vitro study, we compared two clinical vaginal strains of C. albicans, namely,...
Pneumocystis pneumonia (PCP) is a serious fungal infection affecting immunocompromised hosts. Decompensated cirrhosis leads to cirrhosis-associated immune dysfunction (CAID), a form of impaired cellular immunity that may predispose patients to opport...
Yeast cells are passively exposed to ethanol stress during alcoholic fermentation, ultimately impairing cell viability and reducing fermentation efficiency. Arginine, a versatile amino acid, plays a crucial role in regulating cellular responses to va...
RNA interference (RNAi) has emerged as a promising tool for controlling fungal plant pathogens, offering a targeted and environmentally friendly alternative to traditional chemical fungicides. Botrytis cinerea, the causative agent of gray mold diseas...
In this study, the dominant pathogenic fungus of gray spot disease in loquat, which was isolated from postharvest decaying loquat fruits in Zhenjiang, was identified as Pestalotiopsis vismiae (P. vismiae) by morphological characteristics and DNA sequ...
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of immune cells that play a central role in regulating host immune responses during fungal infections. Their recruitment is mediated by pathogen recognition receptors, particularly De...
The Alternaria alternata tangerine pathotype causes Alternaria brown spot, a devastating disease of susceptible tangerine varieties and their hybrids. Alternaria citri toxin (ACT) is the primary virulence factor, but the regulatory mechanisms governi...
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