Bioactive Secondary Metabolites from Fungi

A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Cell Biology, Metabolism and Physiology".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 132

Special Issue Editor


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Guest Editor
1. Department Microbial Drugs, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany
2. Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo 11566, Egypt
Interests: natural product chemistry; structure elucidation; NMR spectroscopy; neurodegenerative disorders; biofilm inhibition; antimicrobial
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Special Issue Information

Dear Colleagues,

Fungi are ubiquitous eukaryotic organisms that can accommodate a vast variety of ecosystems. They vary from being safe edible foods to medicinal mushrooms or sometimes highly toxic variants. From the latest count of the number of fungi on the planet, it was estimated that there are 1.5 million species, with only one-tenth of these explored so far. Therefore, fungal diversity is still a promising research topic. In this Special Issue, we aim to valorize fungal secondary metabolites with interesting bioactivity/bioactivities in terms of their antimicrobial, antiproliferative, anti-inflammatory, antioxidant, and antidiabetic properties, related neurodegenerative disorders, and others.

You are welcome to contribute to this Special Issue by submitting your research and/or review articles related to the topic of “Bioactive Secondary Metabolites from Fungi”. We look forward to receiving your valuable contributions.

Prof. Dr. Sherif S. Ebada
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fungal biodiversity
  • natural products
  • anti-infective
  • antibiotic resistance
  • biofilm inhibition
  • neurodegenerative disorders

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Published Papers (1 paper)

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Review

46 pages, 3153 KiB  
Review
Unveiling the Bioactive Compounds and Therapeutic Potential of Russula: A Comprehensive Review
by Jingya Yang, Samantha C. Karunarathna, Nimesha Patabendige, Entaj Tarafder, Dengji Lou, Yuanqing Zhou and Kalani Hapuarachchi
J. Fungi 2025, 11(5), 341; https://doi.org/10.3390/jof11050341 - 27 Apr 2025
Viewed by 68
Abstract
Russula, a genus of Basidiomycetes with considerable taxonomic diversity, holds significant potential in both traditional and modern medicinal practices. This comprehensive review explores the bioactive compounds identified in various Russula species, detailing their characterization, structural elucidation, and classification. The medicinal properties of [...] Read more.
Russula, a genus of Basidiomycetes with considerable taxonomic diversity, holds significant potential in both traditional and modern medicinal practices. This comprehensive review explores the bioactive compounds identified in various Russula species, detailing their characterization, structural elucidation, and classification. The medicinal properties of these fungi are examined, with a focus on their antioxidant, anti-inflammatory, and immunomodulatory effects, supported by both historical usage and contemporary preclinical pharmacological research. The review also highlights emerging biotechnological applications including environmental remediation, antimicrobial agents, and functional food development. Safety and toxicological considerations are evaluated to provide a balanced perspective on the medicinal use of Russula. The review concludes by summarizing the key findings and emphasizing the importance of Russula in both traditional medicine and future clinically validated innovations. Full article
(This article belongs to the Special Issue Bioactive Secondary Metabolites from Fungi)
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