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Diseases, Volume 6, Issue 4

December 2018 - 27 articles

Cover Story: Many studies have tried to unmask the "French paradox", which consists of low cardiovascular mortality despite a high intake of saturated fat. Mediterranean countries, particularly Crete, are protected, probably due to a specific diet, rich in polyphenols and omega 3. The antioxidant effect of flavonoids in red wine appears to be one of the mechanisms of vascular protection provided by the Mediterranean diet, an epigenetic effect by hormesis mechanism, and a specific anticancer activity studied a lot with resveratrol. Red wine is a soup of antioxidants that can keep time when wine is made in a traditional way (temperatures control, long maceration, and aging in new barrels), and is easily assimilated by the body due to alcohol. Wine consumption is the secret of human healthy longevity. View this paper.
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Articles (27)

  • Feature Paper
  • Review
  • Open Access
96 Citations
9,105 Views
10 Pages

Gut Microbiota, Fusobacteria, and Colorectal Cancer

  • Dervla Kelly,
  • Liying Yang and
  • Zhiheng Pei

11 December 2018

The gut microbiota has emerged as an environmental contributor to colorectal cancer (CRC) in both animal models and human studies. It is now generally accepted that bacteria are ubiquitous colonizers of all exposed human body surfaces, including the...

  • Feature Paper
  • Review
  • Open Access
21 Citations
5,337 Views
15 Pages

11 December 2018

Trans-resveratrol, the most well-known polyphenolic stilbenoid, is found in grapes and accordingly in wine and it is considered to be beneficial for human health, especially towards the aging-linked cell alterations by providing numerous biological a...

  • Case Report
  • Open Access
1 Citations
3,882 Views
4 Pages

5 December 2018

Taking care of patients with delusional parasitosis can be challenging. This report illustrates the added management complexity and ethical dilemmas surrounding a patient who was newly diagnosed with an incurable lung cancer, while at the same time w...

  • Article
  • Open Access
7 Citations
5,188 Views
15 Pages

DOPS Adjuvant Confers Enhanced Protection against Malaria for VLP-TRAP Based Vaccines

  • Gustavo Cabral-Miranda,
  • Ahmed M. Salman,
  • Mona O. Mohsen,
  • Federico L. Storni,
  • Elisa S. Roesti,
  • Murray A. Skinner,
  • Matthew D. Heath,
  • Matthias F. Kramer,
  • Shahid M. Khan and
  • Chris J. Janse
  • + 2 authors

21 November 2018

Vaccination remains the most effective and essential prophylactic tool against infectious diseases. Enormous efforts have been made to develop effective vaccines against malaria but successes remain so far limited. Novel adjuvants may offer a signifi...

  • Feature Paper
  • Review
  • Open Access
38 Citations
10,802 Views
12 Pages

Polyphenol Extracts from Red Wine and Grapevine: Potential Effects on Cancers

  • Souheila Amor,
  • Pauline Châlons,
  • Virginie Aires and
  • Dominique Delmas

18 November 2018

Wine has been popular worldwide for many centuries and currently remains an important component of our diet. Scientific interest in wine and its health effects has grown considerably since the 1990s with the emergence of the “French Paradox&rdq...

  • Feature Paper
  • Case Report
  • Open Access
4 Citations
4,647 Views
5 Pages

ST-Elevation Myocardial Infarction in Coronary Ectasia: A Case Report

  • Hye Ji (Sally) Choi,
  • Christina Luong,
  • Anthony Fung and
  • Teresa S. M. Tsang

16 November 2018

Coronary artery ectasia (CAE) is localized or diffuse dilatation of the coronary artery lumen exceeding the diameter of adjacent healthy reference segments by 1.5 times. It is a rare phenomenon and incidence ranges from 1 to 5% in patients undergoing...

  • Review
  • Open Access
6 Citations
5,207 Views
18 Pages

The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma

  • Ashleigh Parkin,
  • Jennifer Man,
  • Angela Chou,
  • Adnan M Nagrial,
  • Jaswinder Samra,
  • Anthony J Gill,
  • Paul Timpson and
  • Marina Pajic

13 November 2018

Pancreatic cancer is the third leading cause of cancer-related deaths, characterised by poor survival, marked molecular heterogeneity and high intrinsic and acquired chemoresistance. Only 10–20% of pancreatic cancer patients present with surgic...

  • Article
  • Open Access
3 Citations
3,809 Views
7 Pages

Clinical Characteristics of Nursing- and Healthcare-Associated Tuberculosis

  • Toshitaka Suzuki,
  • Tatsuo Kato,
  • Ryoko Ohnishi,
  • Shigeo Yasuda,
  • Kimiyasu Sano,
  • Yohei Shirakami,
  • Masahito Shimizu and
  • Nobuo Murakami

11 November 2018

Tuberculosis remains a serious health problem worldwide. Patients with tuberculosis who also require nursing care due to aging and underlying diseases are considered to have a high mortality rate; however, there are few studies describing detailed ex...

  • Review
  • Open Access
2 Citations
4,537 Views
4 Pages

11 November 2018

Each year, a large number of patients undergo coronary artery bypass grafting surgery (CABG) worldwide. Accumulating evidence suggests that the preoperative administration of statins might be useful in preventing adverse events after CABG. In the pre...

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Diseases - ISSN 2079-9721