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Polyphenol Extracts from Red Wine and Grapevine: Potential Effects on Cancers

1
Université de Bourgogne-Franche Comté, Dijon F-21000, France
2
Centre de Recherche INSERM U1231-Cancer and Adaptative Immune Response Team–Bioactive Molecules and Health research group, Dijon F-21000, France
*
Author to whom correspondence should be addressed.
Diseases 2018, 6(4), 106; https://doi.org/10.3390/diseases6040106
Received: 8 October 2018 / Revised: 13 November 2018 / Accepted: 16 November 2018 / Published: 18 November 2018
(This article belongs to the Special Issue Wine and Vine Components and Health)
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PDF [4521 KB, uploaded 18 November 2018]
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Abstract

Wine has been popular worldwide for many centuries and currently remains an important component of our diet. Scientific interest in wine and its health effects has grown considerably since the 1990s with the emergence of the “French Paradox” concept, correlating moderate wine consumption, a characteristic of the Mediterranean diet, and low incidence of coronary heart diseases. Since then, the positive effects on health, health promotion, disease prevention, and disease prognosis of moderate wine consumption, in particular red wine, have been attributed to its polyphenolic compounds such as resveratrol, quercetin, and other flavonoids acting as antioxidants. Several epidemiological, in vivo and in vitro, studies have reported that moderate red wine or red wine polyphenolic extract consumption may be active in the prevention and treatment of chronic diseases such as cardiovascular disease, metabolic syndrome, degenerative pathologies, and cancer. The aim of this review is to summarize the current findings about the effects of red wine polyphenols on cancer and to discuss how the polyphenolic composition of red wine may influence its chemopreventive properties. View Full-Text
Keywords: red wine; polyphenols; cancers; colorectal red wine; polyphenols; cancers; colorectal
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Amor, S.; Châlons, P.; Aires, V.; Delmas, D. Polyphenol Extracts from Red Wine and Grapevine: Potential Effects on Cancers. Diseases 2018, 6, 106.

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