Journal History
| 2013 | The inaugural issue was released. Diseases was published as a quarterly journal. |
| 2015 | Diseases established the following sections: -Rare Syndrome; -Oncology; -Cardiology. |
| 2016 | Diseases announced the first edition of the Travel Award. |
| 2017 | Diseases was indexed in PubMed—National Library of Medicine (NLM), starting with Volume 1 (Issue 1). |
| 2018 | Editor-in-Chif Prof. Dr. Maurizio Battino visited Diseases Office on 17 August. |
| 2020 | Diseases established the following section: -Comorbidity. |
| 2021 | Diseases was indexed in Emerging Sources Citation Index (ESCI)—Web of Science (Clarivate Analytics), starting with Volume 7 (Issue 1). |
| 2022 |
Diseases was indexed in Scopus (Elsevier), starting with Volume 8 (Issue 1). Diseases published its 500th paper. |
| 2023 | Diseases received its first Impact Factor (3.7). |
| 2024 | Diseases adopted a monthly publication schedule. Comorbidity was discontinued. Immunology was discontinued. |
Editor-in-Chief
| 2013–2014 | Editor-in-Chief: Prof. Dr. Frank Lee Schwartz |
| 2015–present | Editor-in-Chief: Prof. Dr. Maurizio Battino |
| 2025–present | Editor-in-Chief: Prof. Dr. Omar Cauli |
Section Editor-in-Chief
| 2015–present | |
| Section Editor-in-Chief: Prof. Dr. Pedro Bullon for the section on Rare Syndrome | |
| Section Editor-in-Chief: Prof. Dr. Giuseppe Carruba for the section on Oncology | |
| Section Editor-in-Chief: Prof. Dr. Chim C. Lang for the section on Cardiology | |
| 2016–present | Section Editor-in-Chief: Prof. Dr. Carlo Catassi for the section on Gastroenterology |
| 2018–present | Section Editor-in-Chief: Prof. Dr. Gaetano Caramori for the section on Respiratory Diseases |
| Section Editor-in-Chief: Prof. Dr. Charles H. Calisher for the section on Infectious Disease | |
| 2018–2025 | Section Editor-in-Chief: Prof. Dr. Omar Cauli for the section on Neuro-psychiatric Disorders |
| 2025–present | Section Editor-in-Chief: Prof. Dr. Emilio Jirillo for the section on Clinical Nutrition |