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Biosensors, Volume 8, Issue 3

2018 September - 30 articles

Cover Story: Medical devices that monitor biological signals on the skin often rely on the use of rigid and non-breathable electrodes. Specifically, electrodermal activity (EDA), a neurological response quantitatively monitored through sweat, is currently being detected with the use of solid silver/silver chloride (Ag/AgCl) electrodes in a clinical setting. This work presents breathable and flexible EDA electrodes based on Ag/AgCl-coated nylon yarns integrated into various textile substrates, which are compared to conventional rigid Ag/AgCl electrodes. We identified textile properties that affect the detection of the EDA signal, which can impact the future development of wearable systems for long-term EDA monitoring. View this paper.
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Articles (30)

  • Article
  • Open Access
10 Citations
6,632 Views
12 Pages

C-Type Natriuretic Peptide (CNP) Inhibition of Interferon-γ-Mediated Gene Expression in Human Endothelial Cells In Vitro

  • Amy Day,
  • Zoe Jameson,
  • Carolyn Hyde,
  • Bigboy Simbi,
  • Robert Fowkes and
  • Charlotte Lawson

14 September 2018

Cardiovascular diseases, including atherosclerosis, now account for more deaths in the Western world than from any other cause. Atherosclerosis has a chronic inflammatory component involving Th1 pro-inflammatory cytokines such as IFN-γ, which i...

  • Article
  • Open Access
11 Citations
5,396 Views
12 Pages

13 September 2018

An automatic spot identification method is developed for high throughput surface plasmon resonance imaging (SPRi) analysis. As a combination of video accessing, image enhancement, image processing and parallel processing techniques, the method can id...

  • Article
  • Open Access
16 Citations
6,117 Views
16 Pages

Optimization and Application of Electrochemical Transducer for Detection of Specific Oligonucleotide Sequence for Mycobacterium tuberculosis

  • Ricardo A. M. S. Corrêa,
  • Filipe S. Da Cruz,
  • Cátia C. Santos,
  • Thiago C. Pimenta,
  • Diego L. Franco and
  • Lucas F. Ferreira

11 September 2018

In this study, the electropolymerization of 4-hydroxyphenylacetic acid (4-HPA) over graphite electrodes (GE) was optimized, aiming its application as a functionalized electrochemical platform for oligonucleotides immobilization. It was investigated f...

  • Article
  • Open Access
49 Citations
7,154 Views
21 Pages

10 September 2018

In order to exploit plants as environmental biosensors, previous researches have been focused on the electrical signal response of the plants to different environmental stimuli. One of the important outcomes of those researches has been the extractio...

  • Article
  • Open Access
62 Citations
8,052 Views
10 Pages

5 September 2018

In this work, we developed a novel fluorescent sensor by combining molecularly imprinted polymers (MIPs) with graphene quantum dots (GQDs) for the determination of tetracycline (TC) in aqueous samples. Firstly, we developed a one-pot green method to...

  • Article
  • Open Access
15 Citations
6,604 Views
10 Pages

Modified Biosensor for Cholinesterase Inhibitors with Guinea Green B as the Color Indicator

  • Vladimír Pitschmann,
  • Lukáš Matějovský,
  • Martin Lobotka,
  • Jan Dědič,
  • Martin Urban and
  • Michal Dymák

4 September 2018

Colorimetric biosensors of cholinesterase inhibitors are ideal for fast, reliable, and very simple detection of agents in air, in water, and on surfaces. This paper describes an innovation of the Czech Detehit biosensor, which is based on a biochemic...

  • Feature Paper
  • Review
  • Open Access
362 Citations
23,276 Views
27 Pages

Surface Plasmon Resonance Optical Sensor: A Review on Light Source Technology

  • Briliant Adhi Prabowo,
  • Agnes Purwidyantri and
  • Kou-Chen Liu

26 August 2018

The notion of surface plasmon resonance (SPR) sensor research emerged more than eight decades ago from the first observed phenomena in 1902 until the first introduced principles for gas sensing and biosensing in 1983. The sensing platform has been ha...

  • Article
  • Open Access
21 Citations
8,663 Views
17 Pages

Breathable Dry Silver/Silver Chloride Electronic Textile Electrodes for Electrodermal Activity Monitoring

  • Peter A. Haddad,
  • Amir Servati,
  • Saeid Soltanian,
  • Frank Ko and
  • Peyman Servati

24 August 2018

The focus of this study is to design and integrate silver/silver chloride (Ag/AgCl) electronic textile (e-textile) electrodes into different textile substrates to evaluate their ability to monitor electrodermal activity (EDA). Ag/AgCl e-textiles were...

  • Article
  • Open Access
13 Citations
6,317 Views
13 Pages

Design and Fabrication of a BiCMOS Dielectric Sensor for Viscosity Measurements: A Possible Solution for Early Detection of COPD

  • Pouya Soltani Zarrin,
  • Farabi Ibne Jamal,
  • Subhajit Guha,
  • Jan Wessel,
  • Dietmar Kissinger and
  • Christian Wenger

21 August 2018

The viscosity variation of sputum is a common symptom of the progression of Chronic Obstructive Pulmonary Disease (COPD). Since the hydration of the sputum defines its viscosity level, dielectric sensors could be used for the characterization of sput...

  • Article
  • Open Access
36 Citations
7,048 Views
11 Pages

Development of MoSe2 Nano-Urchins as a Sensing Platform for a Selective Bio-Capturing of Escherichia coli Shiga Toxin DNA

  • Jagriti Narang,
  • Annu Mishra,
  • Roberto Pilloton,
  • Alekhya VV,
  • Shikha Wadhwa,
  • Chandra Shekhar Pundir and
  • Manika Khanuja

14 August 2018

The present study was aimed to develop “fluorine doped” tin oxide glass electrode with a MoSe2 nano-urchin based electrochemical biosensor for detection of Escherichia coli Shiga toxin DNA. The study comprises two conductive electrodes, a...

  • Review
  • Open Access
17 Citations
7,073 Views
27 Pages

Synergistic Integration of Laboratory and Numerical Approaches in Studies of the Biomechanics of Diseased Red Blood Cells

  • He Li,
  • Dimitrios P. Papageorgiou,
  • Hung-Yu Chang,
  • Lu Lu,
  • Jun Yang and
  • Yixiang Deng

10 August 2018

In red blood cell (RBC) disorders, such as sickle cell disease, hereditary spherocytosis, and diabetes, alterations to the size and shape of RBCs due to either mutations of RBC proteins or changes to the extracellular environment, lead to compromised...

  • Article
  • Open Access
11 Citations
6,107 Views
14 Pages

7 August 2018

A theoretical analysis and computational study of biomaterial sample detection with surface plasmon resonance (SPR) phenomenon spectroscopy are presented in this work with the objective of achieving more sensitive detection. In this paper, a Fe3O4@Au...

  • Review
  • Open Access
32 Citations
10,973 Views
12 Pages

3 August 2018

Prior to the widespread use of continuous glucose monitoring (CGM), knowledge of the effects of exercise in type 1 diabetes (T1D) was limited to the exercise period, with few studies having the budget or capacity to monitor participants overnight. Re...

  • Communication
  • Open Access
59 Citations
5,831 Views
8 Pages

Cytokeratins Biosensing Using Tilted Fiber Gratings

  • Médéric Loyez,
  • Jacques Albert,
  • Christophe Caucheteur and
  • Ruddy Wattiez

3 August 2018

Optical fiber gratings have widely proven their applicability in biosensing, especially when they are coupled with antibodies for specific antigen recognition. While this is customarily done with fibers coated by a thin metal film to benefit from pla...

  • Article
  • Open Access
16 Citations
6,015 Views
10 Pages

Micro-Raman Spectroscopy for Monitoring of Deposition Quality of High-k Stack Protective Layer onto Nanowire FET Chips for Highly Sensitive miRNA Detection

  • Kristina A. Malsagova,
  • Tatyana O. Pleshakova,
  • Andrey F. Kozlov,
  • Ivan D. Shumov,
  • Mikhail A. Ilnitskii,
  • Andrew V. Miakonkikh,
  • Vladimir P. Popov,
  • Konstantin V. Rudenko,
  • Alexander V. Glukhov and
  • Yuri D. Ivanov
  • + 4 authors

27 July 2018

Application of micro-Raman spectroscopy for the monitoring of quality of high-k (h-k) dielectric protective layer deposition onto the surface of a nanowire (NW) chip has been demonstrated. A NW chip based on silicon-on-insulator (SOI) structures, pro...

  • Article
  • Open Access
12 Citations
5,912 Views
13 Pages

Label-Free Monitoring of Human IgG/Anti-IgG Recognition Using Bloch Surface Waves on 1D Photonic Crystals

  • Alberto Sinibaldi,
  • Agostino Occhicone,
  • Peter Munzert,
  • Norbert Danz,
  • Frank Sonntag and
  • Francesco Michelotti

25 July 2018

Optical biosensors based on one-dimensional photonic crystals sustaining Bloch surface waves are proposed to study antibody interactions and perform affinity studies. The presented approach utilizes two types of different antibodies anchored at the s...

  • Article
  • Open Access
26 Citations
6,858 Views
9 Pages

3D Carbon Microelectrodes with Bio-Functionalized Graphene for Electrochemical Biosensing

  • Suhith Hemanth,
  • Arnab Halder,
  • Claudia Caviglia,
  • Qijin Chi and
  • Stephan Sylvest Keller

19 July 2018

An enzyme-based electrochemical biosensor has been developed with 3D pyrolytic carbon microelectrodes that have been coated with bio-functionalized reduced graphene oxide (RGO). The 3D carbon working electrode was microfabricated using the pyrolysis...

  • Review
  • Open Access
24 Citations
7,926 Views
17 Pages

14 July 2018

The established role of nematic liquid crystals (NLCs) in the recent rapid development of displays has motivated researchers to modulate the electro-optical properties of LCs. Furthermore, adding nanomaterials into NLCs has led to enhancements of the...

  • Review
  • Open Access
40 Citations
12,603 Views
17 Pages

Autoantibodies as Potential Biomarkers in Breast Cancer

  • Jingyi Qiu,
  • Bailey Keyser,
  • Zuan-Tao Lin and
  • Tianfu Wu

13 July 2018

Breast cancer is a major cause of mortality in women; however, technologies for early stage screening and diagnosis (e.g., mammography and other imaging technologies) are not optimal for the accurate detection of cancer. This creates demand for a mor...

  • Review
  • Open Access
58 Citations
10,427 Views
18 Pages

Clinical Assessment of Dental Implant Stability During Follow-Up: What Is Actually Measured, and Perspectives

  • Elisabetta M. Zanetti,
  • Giulia Pascoletti,
  • Michele Calì,
  • Cristina Bignardi and
  • Giordano Franceschini

13 July 2018

The optimization of loading protocols following dental implant insertion requires setting up patient-specific protocols, customized according to the actual implant osseointegration, measured through quantitative, objective methods. Various devices fo...

  • Article
  • Open Access
57 Citations
8,383 Views
16 Pages

The Importance of Multifrequency Impedance Sensing of Endothelial Barrier Formation Using ECIS Technology for the Generation of a Strong and Durable Paracellular Barrier

  • Laverne D. Robilliard,
  • Dan T. Kho,
  • Rebecca H. Johnson,
  • Akshata Anchan,
  • Simon J. O’Carroll and
  • Euan Scott Graham

In this paper, we demonstrate the application of electrical cell-substrate impedance sensing (ECIS) technology for measuring differences in the formation of a strong and durable endothelial barrier model. In addition, we highlight the capacity of ECI...

  • Review
  • Open Access
14 Citations
10,075 Views
24 Pages

Transistors for Chemical Monitoring of Living Cells

  • Benoît Piro,
  • Giorgio Mattana and
  • Steeve Reisberg

We review here the chemical sensors for pH, glucose, lactate, and neurotransmitters, such as acetylcholine or glutamate, made of organic thin-film transistors (OTFTs), including organic electrochemical transistors (OECTs) and electrolyte-gated OFETs...

  • Review
  • Open Access
56 Citations
12,407 Views
16 Pages

29 June 2018

Raman scattering and surface-enhanced Raman scattering (SERS) spectroscopy have demonstrated their potential as ultrasensitive detection techniques in the past decades. Specifically, and as a result of the flourishing of nanotechnology, SERS is nowad...

  • Article
  • Open Access
13 Citations
7,284 Views
11 Pages

29 June 2018

Improvement upon, and expansion of, diagnostic tools for clinical infections have been increasing in recent years. The simplicity and rapidity of techniques are imperative for their adoption and widespread usage at point-of-care. The fabrication and...

  • Review
  • Open Access
18 Citations
6,829 Views
18 Pages

Application of Biosensors Based on Lipid Membranes for the Rapid Detection of Toxins

  • Georgia-Paraskevi Nikoleli,
  • Dimitrios P. Nikolelis,
  • Christina G. Siontorou,
  • Stephanos Karapetis and
  • Marianna-Thalia Nikolelis

26 June 2018

Lipid assemblies in the form of two dimensional films have been used extensively as biosensing platforms. These films exhibit certain similarities with cell membranes, thus providing a suitable means for the immobilization of proteinaceous moieties a...

  • Article
  • Open Access
15 Citations
5,246 Views
12 Pages

25 June 2018

Human activities are accompanied by characteristic sound events, the processing of which might provide valuable information for automated human activity recognition. This paper presents a novel approach addressing the case where one or more human act...

  • Editorial
  • Open Access
23 Citations
5,969 Views
3 Pages

22 June 2018

In recent years, great progress has been made in the development of sensors and biosensors to meet the demands of environmental and food analysis. In this Special Issue, the state of art and the future trends in the field of environmental and food an...

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Biosensors - ISSN 2079-6374