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Biosensors, Volume 14, Issue 3

March 2024 - 42 articles

Cover Story: We are introducing a groundbreaking smartphone-based analyzing and reporting system (SBARS) for lupus nephritis (LN) biomarker detection. Traditional healthcare systems often face challenges in efficiency and patient coverage. The SBARS utilizes a portable microscopic reader and smartphone app, eliminating the need for expensive large equipment. Through innovative image processing techniques, it analyzes the intensity of biomarker signals with impressive accuracy. Our system demonstrated comparable performance to commercial scanners in detecting potential LN biomarkers and it allows for discriminating LN patients with active renal disease from healthy controls with remarkable precision. The SBARS may help revolutionize healthcare with accessible, cost-effective, and accurate biomarker detection. View this paper
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Articles (42)

  • Article
  • Open Access
7 Citations
4,138 Views
14 Pages

Sensitivity of Electrocardiogram on Electrode-Pair Locations for Wearable Devices: Computational Analysis of Amplitude and Waveform Distortion

  • Kiyoto Sanjo,
  • Kazuki Hebiguchi,
  • Cheng Tang,
  • Essam A. Rashed,
  • Sachiko Kodera,
  • Hiroyoshi Togo and
  • Akimasa Hirata

21 March 2024

An electrocardiogram (ECG) is used to observe the electrical activity of the heart via electrodes on the body surface. Recently, an ECG with fewer electrodes, such as a bipolar ECG in which two electrodes are attached to the chest, has been employed...

  • Article
  • Open Access
6 Citations
4,402 Views
14 Pages

Customizable Nichrome Wire Heaters for Molecular Diagnostic Applications

  • Juhee Lim,
  • Won Han,
  • Le Tran Huy Thang,
  • Yong Wook Lee and
  • Joong Ho Shin

20 March 2024

Accurate sample heating is vital for nucleic acid extraction and amplification, requiring a sophisticated thermal cycling process in nucleic acid detection. Traditional molecular detection systems with heating capability are bulky, expensive, and pri...

  • Article
  • Open Access
3 Citations
2,633 Views
18 Pages

20 March 2024

Two fluorescent molecularly imprinted polymers (MIPs) were developed for pepsin enzyme utilising fluorescein and rhodamine b. The main difference between both dyes is the presence of two (diethylamino) groups in the structure of rhodamine b. Conseque...

  • Review
  • Open Access
5 Citations
4,563 Views
23 Pages

Hydrogel-Gated FETs in Neuromorphic Computing to Mimic Biological Signal: A Review

  • Sankar Prasad Bag,
  • Suyoung Lee,
  • Jaeyoon Song and
  • Jinsink Kim

19 March 2024

Hydrogel-gated synaptic transistors offer unique advantages, including biocompatibility, tunable electrical properties, being biodegradable, and having an ability to mimic biological synaptic plasticity. For processing massive data with ultralow powe...

  • Article
  • Open Access
2 Citations
2,850 Views
22 Pages

Microwave Imaging System Based on Signal Analysis in a Planar Environment for Detection of Abdominal Aortic Aneurysms

  • Andrea Martínez-Lozano,
  • Roberto Gutierrez,
  • Carlos G. Juan,
  • Carolina Blanco-Angulo,
  • Héctor García-Martínez,
  • Germán Torregrosa,
  • José María Sabater-Navarro and
  • Ernesto Ávila-Navarro

18 March 2024

A proof-of-concept of a microwave imaging system for the fast detection of abdominal aortic aneurysms is shown. This experimental technology seeks to overcome the factors hampering the fast screening for these aneurysms with the usual equipment, such...

  • Review
  • Open Access
16 Citations
11,338 Views
24 Pages

Continuous and Non-Invasive Lactate Monitoring Techniques in Critical Care Patients

  • Jose-Luis Lafuente,
  • Samuel González,
  • Clara Aibar,
  • Desirée Rivera,
  • Eva Avilés and
  • Juan-Jose Beunza

18 March 2024

Lactate, once merely regarded as an indicator of tissue hypoxia and muscular fatigue, has now gained prominence as a pivotal biomarker across various medical disciplines. Recent research has unveiled its critical role as a high-value prognostic marke...

  • Article
  • Open Access
3 Citations
2,777 Views
15 Pages

Advancing Point-of-Care Diagnosis: Digitalizing Combinatorial Biomarker Signals for Lupus Nephritis

  • Jiechang Guo,
  • Aygun Teymur,
  • Chenling Tang,
  • Ramesh Saxena and
  • Tianfu Wu

18 March 2024

To improve the efficiency and patient coverage of the current healthcare system, user-friendly novel homecare devices are urgently needed. In this work, we developed a smartphone-based analyzing and reporting system (SBARS) for biomarker detection in...

  • Review
  • Open Access
13 Citations
5,574 Views
37 Pages

Aptamers and Nanobodies as New Bioprobes for SARS-CoV-2 Diagnostic and Therapeutic System Applications

  • Ki Sung Park,
  • Tae-In Park,
  • Jae Eon Lee,
  • Seo-Yeong Hwang,
  • Anna Choi and
  • Seung Pil Pack

15 March 2024

The global challenges posed by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic have underscored the critical importance of innovative and efficient control systems for addressing future pandemics. The most effective way to c...

  • Review
  • Open Access
15 Citations
6,381 Views
21 Pages

Detection of Parasites in the Field: The Ever-Innovating CRISPR/Cas12a

  • Xin Li,
  • Zhisheng Dang,
  • Wenqiang Tang,
  • Haoji Zhang,
  • Jianwei Shao,
  • Rui Jiang,
  • Xu Zhang and
  • Fuqiang Huang

14 March 2024

The rapid and accurate identification of parasites is crucial for prompt therapeutic intervention in parasitosis and effective epidemiological surveillance. For accurate and effective clinical diagnosis, it is imperative to develop a nucleic-acid-bas...

  • Article
  • Open Access
2,982 Views
12 Pages

Systematic Assessment of Human CCR7 Signalling Using NanoBRET Biosensors Points towards the Importance of the Cellular Context

  • Nathan Vanalken,
  • Katrijn Boon,
  • Martyna Szpakowska,
  • Andy Chevigné,
  • Dominique Schols and
  • Tom Van Loy

14 March 2024

The human CC chemokine receptor 7 (CCR7) is activated by two natural ligands, CC chemokine ligand 19 (CCL19) and 21 (CCL21). The CCL19-CCL21-CCR7 axis has been extensively studied in vitro, but there is still debate over whether CCL21 is an overall w...

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Biosensors - ISSN 2079-6374