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Biosensors
Special Issues
Plasmonic Based Biosensors
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Special Issue "Plasmonic Based Biosensors"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".

Deadline for manuscript submissions: 20 September 2023 | Viewed by 2085

Special Issue Editors

Dr. Shuohui Cao

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Guest Editor
Department of Electronic Science, Xiamen University, Xiamen 361005, China
Interests: biosensors; bioelectronics
Prof. Dr. Yu Tao
E-Mail Website
Guest Editor
Laboratory of Biomaterials and Translational Medicine, Sun Yat-sen University, Guangzhou 510630, China
Interests: biosensors; nanomedicine
Prof. Dr. Xiaoqing Liu
E-Mail Website
Guest Editor
School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangdong 510006, China
Interests: cell analysis; plasmonic electrochemistry
Dr. Lei Zhang

E-Mail Website
Guest Editor
School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China
Interests: biosensors; nanomaterials; super-resolution imaging

Special Issue Information

Dear Colleagues,

Biosensors are playing increasingly important roles in medical diagnosis and in the fight against threats to human health, especially during the COVID-19 pandemic which is currently having substantial global economic and social impacts. Attributed to their high sensitivity, even at a single-molecule level, plasmonic techniques are promising to accelerate the development of effective biosensors, with the rational combination of nanomaterials, biotechniques, and instrumentation.

This Special Issue focuses on the recent advances in plasmonic-based biosensors and their applications both in vitro and in vivo. We invite submissions of research which contribute to bioanalysis fields including, but not limited to, surface plasmon resonance sensors, localized surface plasmon resonance sensors, optical and electrical sensors, plasmonic spectroscopy for sensing, plasmonic imaging for sensing, new plasmonic materials and structures for sensing, as well as innovative biorecognition mechanisms and designs. Review articles and research articles related to the above contributions are welcome.

Dr. Shuohui Cao
Dr. Yu Tao
Prof. Dr. Xiaoqing Liu
Dr. Lei Zhang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensor
  • plasmonic effect
  • plasmonics materials
  • plasmonic device
  • plasmonic spectroscopy
  • plasmonic imaging
  • photoelectric sensor
  • biomarker
  • diagnosis
  • bioanalysis

Published Papers (3 papers)

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Research

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Article
Ultrasensitive Detection of C-Reactive Protein by a Novel Nanoplasmonic Immunoturbidimetry Assay
by
Tang Dang
,
Zhenyu Li
,
Liyuan Zhao
,
Wei Zhang
,
Liping Huang
,
Fanling Meng
,
Gang Logan Liu
and
Wenjun Hu
Biosensors 2022, 12(11), 958; https://doi.org/10.3390/bios12110958 - 02 Nov 2022
Viewed by 714
Abstract
Nanotechnology has attracted much attention, and may become the key to a whole new world in the fields of food, agriculture, building materials, machinery, medicine, and electrical engineering, because of its unique physical and chemical properties, including high surface area and outstanding electrical [...] Read more.
Nanotechnology has attracted much attention, and may become the key to a whole new world in the fields of food, agriculture, building materials, machinery, medicine, and electrical engineering, because of its unique physical and chemical properties, including high surface area and outstanding electrical and optical properties. The bottom-up approach in nanofabrication involves the growth of particles, and we were inspired to propose a novel nanoplasmonic method to detect the formation of nanoparticles in real time. This innovative idea may contribute to the promotion of nanotechnology development. An increase in nanometer particle size leads to optical extinction or density (OD)-value changes in our nanosensor chip at a specific wavelength measured in a generic microplate reader. Moreover, in applying this method, an ultrasensitive nanoplasmonic immunoturbidimetry assay (NanoPITA) was carried out for the high-throughput quantification of hypersensitive C-reactive protein (CRP), a well-known biomarker of cardiovascular, inflammatory, and tumor diseases. The one-step detection of the CRP concentration was completed in 10 min with high fidelity, using the endpoint analysis method. The new NanoPITA method not only produced a linear range from 1 ng/mL to 500 ng/mL CRP with the detection limit reduced to 0.54 ng/mL, which was an improvement of over 1000 times, with respect to regular immunoturbidity measurement, but was also effective in blood detection. This attractive method, combined with surface plasmon resonance and immunoturbidimetry, may become a new technology platform in the application of biological detection. Full article
(This article belongs to the Special Issue Plasmonic Based Biosensors)
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Review

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Review
Wavelength-Dependent Metal-Enhanced Fluorescence Biosensors via Resonance Energy Transfer Modulation
by
Seungah Lee
and
Seong Ho Kang
Biosensors 2023, 13(3), 376; https://doi.org/10.3390/bios13030376 - 13 Mar 2023
Viewed by 501
Abstract
Fluorescence can be enhanced or quenched depending on the distance between the surface of a metal nanoparticle and the fluorophore molecule. Fluorescence enhancement by nearby metal particles is called metal-enhanced fluorescence (MEF). MEF shows promising potential in the field of fluorescence-based biological sensing. [...] Read more.
Fluorescence can be enhanced or quenched depending on the distance between the surface of a metal nanoparticle and the fluorophore molecule. Fluorescence enhancement by nearby metal particles is called metal-enhanced fluorescence (MEF). MEF shows promising potential in the field of fluorescence-based biological sensing. MEF-based biosensor systems generally fall into two platform categories: (1) a two/three-dimensional scaffold, or (2) a colloidal suspension. This review briefly summarizes the application studies using wavelength-dependent carbon dots (UV-VIS), noble metals (VIS), and upconversion nanoparticles (NIR to VIS), representative nanomaterials that contribute to the enhancement of fluorescence through the resonance energy transfer modulation and then presents a perspective on this topic. Full article
(This article belongs to the Special Issue Plasmonic Based Biosensors)
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Review
Recent Progress in Plasmonic based Electrochemiluminescence Biosensors: A Review
by
Cheng Ma
,
Zhichen Zhang
,
Tingting Tan
and
Jun-Jie Zhu
Biosensors 2023, 13(2), 200; https://doi.org/10.3390/bios13020200 - 29 Jan 2023
Viewed by 527
Abstract
Electrochemiluminescence (ECL) analysis has become a powerful tool in recent biomarker detection and clinic diagnosis due to its high sensitivity and broad linear range. To improve the analytical performance of ECL biosensors, various advanced nanomaterials have been introduced to regulate the ECL signal [...] Read more.
Electrochemiluminescence (ECL) analysis has become a powerful tool in recent biomarker detection and clinic diagnosis due to its high sensitivity and broad linear range. To improve the analytical performance of ECL biosensors, various advanced nanomaterials have been introduced to regulate the ECL signal such as graphene, gold nanomaterials, and quantum dots. Among these nanomaterials, some plasmonic nanostructures play important roles in the fabrication of ECL biosensors. The plasmon effect for the ECL signal includes ECL quenching by resonant energy transfer, ECL enhancement by surface plasmon resonance enhancement, and a change in the polarized angle of ECL emission. The influence can be regulated by the distance between ECL emitters and plasmonic materials, and the characteristics of polarization angle-dependent surface plasmon coupling. This paper outlines the recent advances of plasmonic based ECL biosensors involving various plasmonic materials including noble metals and semiconductor nanomaterials. The detection targets in these biosensors range from small molecules, proteins, nucleic acids, and cells thanks to the plasmonic effect. In addition to ECL biosensors, ECL microscopy analysis with plasmonic materials is also highlighted because of the enhanced ECL image quality by the plasmonic effect. Finally, the future opportunities and challenges are discussed if more plasmonic effects are introduced into the ECL realm. Full article
(This article belongs to the Special Issue Plasmonic Based Biosensors)
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