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Biosensors, Volume 14, Issue 4

April 2024 - 56 articles

Cover Story: A rapid, selective assay using 35 nm gold nanoparticles to detect a common EGFR mutation linked to non-small-cell lung cancer was developed. Gold nanoparticles were synthesized with high stability and monodispersity via a seed-mediated growth method and further functionalized with a 16 bp thiolated oligonucleotide using a pH-assisted approach. Our assay achieved a detection limit of 1.5 ug mL−1 using a 0.15 nmol dm−3 gold nanoparticle concentration. This study offers a simple, cost-effective method for detecting lung cancer-related DNA sequences, potentially enabling early diagnosis. View this paper
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Articles (56)

  • Article
  • Open Access
1 Citations
2,986 Views
11 Pages

Body Size, Cerebral Blood Flow, Ambient Temperature, and Relative Brain Temperatures in Newborn Infants under Incubator Care

  • Satoko Fukaya,
  • Sachiko Iwata,
  • Kennosuke Tsuda,
  • Akiko Hirose,
  • Masahiro Kinoshita,
  • Shinji Saitoh and
  • Osuke Iwata

22 April 2024

Subtle changes in body temperature affect the outcomes of ill newborns. However, the temperature profile of neonatal brains remains largely unknown. In open-cot care, increased cerebral perfusion is correlated with higher superficial brain temperatur...

  • Article
  • Open Access
9 Citations
2,226 Views
13 Pages

22 April 2024

Polarization imaging and sensing techniques have shown great potential for biomedical and clinical applications. As a novel optical biosensing technology, Mueller matrix polarimetry can provide abundant microstructural information of tissue samples....

  • Article
  • Open Access
1 Citations
2,982 Views
12 Pages

22 April 2024

Organic electrochemical transistors appear as an alternative for relatively low-cost, easy-to-operate biosensors due to their intrinsic amplification. Herein, we present the fabrication, characterization, and validation of an immuno-detection system...

  • Article
  • Open Access
4 Citations
2,615 Views
16 Pages

Development of FRET Biosensor to Characterize CSK Subcellular Regulation

  • Mingxing Ouyang,
  • Yujie Xing,
  • Shumin Zhang,
  • Liting Li,
  • Yan Pan and
  • Linhong Deng

20 April 2024

C-terminal Src kinase (CSK) is the major inhibitory kinase for Src family kinases (SFKs) through the phosphorylation of their C-tail tyrosine sites, and it regulates various types of cellular activity in association with SFK function. As a cytoplasmi...

  • Article
  • Open Access
9 Citations
6,975 Views
21 Pages

20 April 2024

Wearable health devices (WHDs) are rapidly gaining ground in the biomedical field due to their ability to monitor the individual physiological state in everyday life scenarios, while providing a comfortable wear experience. This study introduces a no...

  • Article
  • Open Access
2 Citations
2,607 Views
15 Pages

Optimizing Microfluidic Impedance Cytometry by Bypass Electrode Layout Design

  • Guangzu Wu,
  • Zhiwei Zhang,
  • Manman Du,
  • Dan Wu,
  • Junting Zhou,
  • Tianteng Hao and
  • Xinwu Xie

19 April 2024

Microfluidic impedance cytometry (MIC) has emerged as a popular technique for single-cell analysis. Traditional MIC electrode designs consist of a pair of (or three) working electrodes, and their detection performance needs further improvements for m...

  • Article
  • Open Access
10 Citations
4,044 Views
13 Pages

19 April 2024

Tyrosinase (TYR) emerges as a key enzyme that exerts a regulatory influence on the synthesis of melanin, thereby assuming the role of a critical biomarker for the detection of melanoma. Detecting the authentic concentration of TYR in the skin remains...

  • Review
  • Open Access
9 Citations
4,098 Views
14 Pages

Advances in Biosensors for the Rapid Detection of Marine Biotoxins: Current Status and Future Perspectives

  • Xiangwei Zhu,
  • Yufa Zhao,
  • Long Wu,
  • Xin Gao,
  • Huang Huang,
  • Yu Han and
  • Ting Zhu

19 April 2024

Marine biotoxins (MBs), harmful metabolites of marine organisms, pose a significant threat to marine ecosystems and human health due to their diverse composition and widespread occurrence. Consequently, rapid and efficient detection technology is cru...

  • Article
  • Open Access
2 Citations
2,394 Views
20 Pages

A Smartphone-Based M-Health Monitoring System for Arrhythmia Diagnosis

  • Jun Luo,
  • Mengru Zhang,
  • Haohang Li,
  • Dan Tao and
  • Ruipeng Gao

18 April 2024

Deep learning technology has been widely adopted in the research of automatic arrhythmia detection. However, there are several limitations in existing diagnostic models, e.g., difficulties in extracting temporal information from long-term ECG signals...

  • Review
  • Open Access
8 Citations
4,175 Views
25 Pages

PCR Independent Strategy-Based Biosensors for RNA Detection

  • Xinran Li,
  • Haoqian Wang,
  • Xin Qi,
  • Yi Ji,
  • Fukai Li,
  • Xiaoyun Chen,
  • Kai Li and
  • Liang Li

18 April 2024

RNA is an important information and functional molecule. It can respond to the regulation of life processes and is also a key molecule in gene expression and regulation. Therefore, RNA detection technology has been widely used in many fields, especia...

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Biosensors - ISSN 2079-6374