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Vaccines, Volume 10, Issue 3

March 2022 - 141 articles

Cover Story: Mozambique introduced monovalent rotavirus vaccine (Rotarix®) in September 2015. We evaluated the effectiveness of Rotarix® under conditions of routine use in Mozambican children hospitalized with acute gastroenteritis (AGE). The adjusted VE of ≥1 dose in children aged 6–11 months was 52.0% (95% CI, −11, 79), and −24.0% (95% CI, −459, 62) among children aged 12–23 months. Estimated VE was lower in stunted than in non-stunted children (14% (95% CI, −138, 66) vs. 59% (95% CI, −125, 91)). Rotavirus vaccination appeared moderately effective against rotavirus gastroenteritis hospitalization in young Mozambican children. VE point estimates were lower in older and stunted children, although confidence intervals were wide. These findings provide additional evidence for other high-mortality countries considering rotavirus vaccine introduction. View this paper.
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Articles (141)

  • Article
  • Open Access
4 Citations
2,970 Views
11 Pages

Susceptibility to Vaccine-Preventable Diseases in Four Districts of Xaysomboun Province, Lao People’s Democratic Republic

  • Siriphone Virachith,
  • Mapor Lao,
  • Magnoula Inthepphavong,
  • Saythong Inthalath,
  • Judith M. Hübschen,
  • Sengchanh Kounnavong,
  • Somphou Sayasone and
  • Antony P. Black

17 March 2022

Xaysomboun province has some of the lowest health indicators in Lao People’s Democratic Republic (PDR). This cross-sectional study aimed to determine the vaccination, susceptibility and exposure status of the population to hepatitis B virus (HB...

  • Article
  • Open Access
14 Citations
3,357 Views
15 Pages

Whole Proteome-Based Therapeutic Targets Annotation and Designing of Multi-Epitope-Based Vaccines against the Gram-Negative XDR-Alcaligenes faecalis Bacterium

  • Metab Alharbi,
  • Abdulrahman Alshammari,
  • Abdullah F. Alasmari,
  • Saud Alharbi,
  • Muhammad Tahir ul Qamar,
  • Sumra Wajid Abbasi,
  • Bilal Shaker and
  • Sajjad Ahmad

17 March 2022

This study involved therapeutic targets mining for the extremely drug-resistant bacterial species called Alcaligenes faecalis, which is known to infect humans. The infections caused by this species in different parts of the human body have been linke...

  • Article
  • Open Access
9 Citations
4,157 Views
22 Pages

Cytokine Adjuvants IL-7 and IL-15 Improve Humoral Responses of a SHIV LentiDNA Vaccine in Animal Models

  • Laury-Anne Leroy,
  • Alice Mac Donald,
  • Aditi Kandlur,
  • Deepanwita Bose,
  • Peng Xiao,
  • Jean Gagnon,
  • François Villinger and
  • Yahia Chebloune

17 March 2022

HIV-1 remains a major public health issue worldwide in spite of efficacious antiviral therapies, but with no cure or preventive vaccine. The latter has been very challenging, as virus infection is associated with numerous escape mechanisms from host...

  • Article
  • Open Access
2 Citations
3,091 Views
13 Pages

Flu Vaccination Coverage and Predictors of Non-Vaccination in Military Health Corps Personnel 2016–2017 and 2019–2021

  • María Julia Ajejas Bazán,
  • Francisco Javier Pérez-Rivas,
  • Julia Wärnberg,
  • Carlos Fuentes Mora,
  • Lucía Elena Ballester Orcal,
  • Jose Manuel Gómez Crespo,
  • Candelas López-López,
  • Silvia Domínguez-Fernández,
  • Milagros Rico-Blázquez and
  • Napoleón Pérez-Farinós

17 March 2022

(1) Background: Vaccination is the most effective intervention to control seasonal influenza morbidity and mortality. The present study aimed to determine the influenza vaccination coverage in the Military Health Corps personnel in the 2020–202...

  • Communication
  • Open Access
25 Citations
3,981 Views
9 Pages

SARS-CoV-2 Omicron Symptomatic Infections in Previously Infected or Vaccinated South African Healthcare Workers

  • Marta C. Nunes,
  • Sthembile Mbotwe-Sibanda,
  • Vicky L. Baillie,
  • Gaurav Kwatra,
  • Ricardo Aguas,
  • Shabir A. Madhi and
  • on behalf of the Wits VIDA HCW Study Group

17 March 2022

We investigated Omicron infections among healthcare workers (HCW) presenting with symptoms of SARS-CoV-2 infection and evaluated the protective effect of vaccination or prior infection. Between 24 November and 31 December 2021, HCW in Johannesburg, S...

  • Article
  • Open Access
3 Citations
3,126 Views
10 Pages

Seroprevalence against Diphtheria in Pregnant Women and Newborns in Colombia: New Arguments to Promote Maternal Immunization

  • Laura María Rivera-Santamaría,
  • Doracelly Hincapié-Palacio,
  • Jesús Ochoa,
  • Felipe Vargas-Restrepo,
  • Marta C. Ospina and
  • Seti Buitrago-Giraldo

17 March 2022

The tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine is recommended during pregnancy for neonatal protection against pertussis, although little is known of the protection it provides against diphtheria. The work used...

  • Review
  • Open Access
7 Citations
7,132 Views
19 Pages

Genetic Modification of T Cells for the Immunotherapy of Cancer

  • Suzanne Quinn,
  • Natasha Lenart,
  • Victoria Dronzek,
  • Gina M. Scurti,
  • Nasheed M. Hossain and
  • Michael I. Nishimura

16 March 2022

Immunotherapy is a beneficial treatment approach for multiple cancers, however, current therapies are effective only in a small subset of patients. Adoptive cell transfer (ACT) is a facet of immunotherapy where T cells targeting the tumor cells are t...

  • Article
  • Open Access
9 Citations
3,096 Views
10 Pages

Potential Antiviral Activity of Lactiplantibacillus plantarum KAU007 against Influenza Virus H1N1

  • Irfan A. Rather,
  • Majid Rasool Kamli,
  • Jamal S. M. Sabir and
  • Bilal Ahmad Paray

16 March 2022

The development of antiviral resistance has exacerbated a growing threat to public health. As a result, there is increasing demand for unconventional antivirals that can effectively replace the presently in-use drugs. Lactic acid-producing bacteria (...

  • Article
  • Open Access
11 Citations
3,655 Views
19 Pages

How to Motivate SARS-CoV-2 Convalescents to Receive a Booster Vaccination? Influence on Vaccination Willingness

  • Elias Kowalski,
  • Andreas Stengel,
  • Axel Schneider,
  • Miriam Goebel-Stengel,
  • Stephan Zipfel and
  • Johanna Graf

16 March 2022

(1) Background: Booster vaccinations for SARS-CoV-2 convalescents are essential for achieving herd immunity. For the first time, this study examined the influencing factors of vaccination willingness among SARS-CoV-2 infected individuals and identifi...

  • Commentary
  • Open Access
25 Citations
10,152 Views
9 Pages

COVID-19 Vaccines and Hyperglycemia—Is There a Need for Postvaccination Surveillance?

  • Samson Mathews Samuel,
  • Elizabeth Varghese,
  • Chris R. Triggle and
  • Dietrich Büsselberg

16 March 2022

The COVID-19 vaccines currently in use have undoubtedly played the most significant role in combating the SARS-CoV-2 virus and reducing disease severity and the risk of death among those affected, especially among those with pre-existing conditions,...

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Vaccines - ISSN 2076-393X