Global Analysis of SARS-CoV-2 Serology

Dear Colleagues,

The outbreak of SARS-CoV-2 in late 2019 caused a pandemic, currently in its third wave, with a huge medical, societal, and economic impact. Based on detailed knowledge of the viral genome and the major proteins of the virus, molecular and serological assays have been rapidly developed. A wide range of serological assays (both in-house as well as commercial) for SARS-CoV-2 by now have been validated and implemented. These have been instrumental for diagnostics and for monitoring the course and severity of COVID-19. For now and in the future, (functional) serological assays will (also) be important to monitor vaccine coverage against emerging variants of SARS-CoV-2. The global aspect and impact of SARS-CoV-2 serology is illustrated through the emergence of variant strains in the UK, in Brazil, in South Africa, and in India. In this Special Issue, we aim to bring together views from clinical and basic specialists around the world on the pathogen, its biology, and the vaccines. We welcome your submissions.