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Vaccines, Volume 10, Issue 4

2022 April - 150 articles

Cover Story: Seasonal influenza can cause severe morbidity, mortality, and financial burden in pediatric and adult populations. Before the COVID-19 pandemic, 15% to 45% of children were infected yearly with influenza viruses. The influenza vaccine (IV) is considered the most effective way to prevent influenza and influenza-related complications. Up to 2018, only 5 out of 30 EU/EEA member states offered seasonal IV to healthy children or adolescents free of charge. Due to the high burden of influenza and the low IV coverage in the pediatric population, this study aims to assess the effectiveness of the influenza vaccine in preventing influenza infection in a cohort of healthy children. Our findings showed high influenza vaccine effectiveness, as well as no additional or prolonged effects of the influenza vaccine, suggesting the importance of seasonal flu vaccination every year. View this paper.
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Articles (150)

  • Article
  • Open Access
29 Citations
6,992 Views
26 Pages

Economic-Related Inequalities in Zero-Dose Children: A Study of Non-Receipt of Diphtheria–Tetanus–Pertussis Immunization Using Household Health Survey Data from 89 Low- and Middle-Income Countries

  • Nicole Bergen,
  • Bianca O. Cata-Preta,
  • Anne Schlotheuber,
  • Thiago M. Santos,
  • M. Carolina Danovaro-Holliday,
  • Tewodaj Mengistu,
  • Samir V. Sodha,
  • Daniel R. Hogan,
  • Aluisio J. D. Barros and
  • Ahmad Reza Hosseinpoor

18 April 2022

Despite advances in scaling up new vaccines in low- and middle-income countries, the global number of unvaccinated children has remained high over the past decade. We used 2000–2019 household survey data from 154 surveys representing 89 low- an...

  • Article
  • Open Access
9 Citations
3,936 Views
15 Pages

18 April 2022

Human papillomavirus (HPV) infection is a risk factor for head and neck cancers (HNC). HPV-related head and neck cancers are preventable through vaccination. This study aimed to assess the attitudes towards HPV vaccination among adults in Poland, wit...

(This article belongs to the Special Issue Feature Papers of Epidemiology and Vaccines)
  • Article
  • Open Access
20 Citations
3,274 Views
14 Pages

18 April 2022

Seneca Valley virus (SVV), also known as Senecavirus A (SVA), is a non-enveloped and single-strand positive-sense RNA virus, which belongs to the genus of Senecavirus within the family Picornaviridae. Porcine idiopathic vesicular disease (PIVD) cause...

(This article belongs to the Section Vaccine Design, Development, and Delivery)
  • Article
  • Open Access
16 Citations
3,301 Views
14 Pages

The Impact and Vaccination Coverage of Seasonal Influenza among Children Aged 6–59 Months in China in 2017–2018: An Internet Panel Survey

  • Hangjie Zhang,
  • Xiang Ren,
  • Keqing Tian,
  • Jianxing Yu,
  • Aiqing Zhu,
  • Lijie Zhang,
  • George Fu Gao and
  • Zhongjie Li

18 April 2022

Seasonal influenza vaccination is highly recommended for 6–59-month-old children. To determine the impact of seasonal influenza and the factors affecting influenza vaccine uptake among children, we conducted an opt-in Internet panel survey of p...

(This article belongs to the Section Influenza Virus Vaccines)
  • Brief Report
  • Open Access
12 Citations
3,264 Views
10 Pages

COVID-19 Neutralizing Antibodies in Breast Milk of Mothers Vaccinated with Three Different Vaccines in Mexico

  • Olivia Cabanillas-Bernal,
  • Karla Cervantes-Luevano,
  • Gonzalo Isai Flores-Acosta,
  • Johanna Bernáldez-Sarabia and
  • Alexei F. Licea-Navarro

18 April 2022

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused the largest pandemic of this century, and all aspects of this virus are being studied. The efforts to mitigate the negative effects associated with the SARS-CoV-2 pandemic have c...

(This article belongs to the Topic Global Analysis of SARS-CoV-2 Serology)
  • Article
  • Open Access
17 Citations
4,705 Views
16 Pages

Self-Reported COVID-19 Vaccine Hesitancy and Willingness to Pay: A Cross-Sectional Survey in Thailand

  • Kulpatsorn Mueangpoon,
  • Chapipak Inchan,
  • Panithan Kaewmuneechoke,
  • Peerunda Rattana,
  • Supanut Budsratid,
  • Suthasinee Japakiya,
  • Pitchayanont Ngamchaliew and
  • Polathep Vichitkunakorn

16 April 2022

This study aimed to estimate the prevalence and influencing factors of COVID-19 vaccine hesitancy and willingness to pay in Thailand. A descriptive cross-sectional study was conducted from 13 September 2021 to 14 January 2022. Data were collected usi...

(This article belongs to the Special Issue SARS-CoV-2 (COVID-19) Vaccination and Compliance/Hesitancy)
  • Article
  • Open Access
36 Citations
7,638 Views
17 Pages

COVID-19 Vaccine Hesitancy and Determinants of Acceptance among Healthcare Workers, Academics and Tertiary Students in Nigeria

  • Emmanuel O. Njoga,
  • Philip P. Mshelbwala,
  • Kenneth O. Abah,
  • Olajoju J. Awoyomi,
  • Kinley Wangdi,
  • Shedrach B. Pewan,
  • Felix A. Oyeleye,
  • Haruna B. Galadima,
  • Salisu A. Alhassan and
  • Charles E. Rupprecht
  • + 9 authors

15 April 2022

The COVID-19 pandemic has resulted in millions of human deaths, prompting the rapid development and regulatory approval of several vaccines. Although Nigeria implemented a COVID-19 vaccination program on 15 March 2021, low vaccine acceptance remains...

  • Article
  • Open Access
3 Citations
4,808 Views
16 Pages

Balancing Benefits and Harms of COVID-19 Vaccines: Lessons from the Ongoing Mass Vaccination Campaign in Lombardy, Italy

  • Giovanni Corrao,
  • Federico Rea,
  • Matteo Franchi,
  • Danilo Cereda,
  • Antonio Barone,
  • Catia Rosanna Borriello,
  • Giulia Petra Della Valle,
  • Michele Ercolanoni,
  • Jose Jara and
  • Guido Bertolaso
  • + 11 authors

15 April 2022

Background. Limited evidence exists on the balance between the benefits and harms of the COVID-19 vaccines. The aim of this study is to compare the benefits and safety of mRNA-based (Pfizer-BioNTech and Moderna) and adenovirus-vectored (Oxford-AstraZ...

(This article belongs to the Special Issue COVID-19 Vaccines: The Way Back to Normal Life Is Now Marked)
  • Article
  • Open Access
30 Citations
4,455 Views
14 Pages

Social Capital, Urbanization Level, and COVID-19 Vaccination Uptake in the United States: A National Level Analysis

  • Shan Qiao,
  • Zhenlong Li,
  • Jiajia Zhang,
  • Xiaowen Sun,
  • Camryn Garrett and
  • Xiaoming Li

15 April 2022

Vaccination remains the most promising mitigation strategy for the COVID-19 pandemic. However, existing literature shows significant disparities in vaccination uptake in the United States. Using publicly available national-level data, we aimed to exp...

(This article belongs to the Special Issue COVID-19 Vaccination and Globe Public Health)
  • Editorial
  • Open Access
5 Citations
2,647 Views
3 Pages

Recent Advances in Vaccine Technology and Design

  • Rossella Cianci and
  • Laura Franza

15 April 2022

If up until three years ago, infectious diseases were a lesser concern when compared to non-communicable diseases in Western countries, the ongoing pandemic has reminded us that things are not so clean-cut [...]

(This article belongs to the Special Issue Genomic Medicine and Advances in Vaccine Technology and Development 2.0)
  • Article
  • Open Access
71 Citations
7,628 Views
14 Pages

15 April 2022

Due to the emergence of various highly contagious variants of SARS-CoV-2, vaccine boosters were adopted as a complementary strategy in different countries. This strategy has, however, posed another challenge for the national authorities to convince t...

(This article belongs to the Collection COVID-19 Vaccine Hesitancy: Correlates and Interventions)
  • Article
  • Open Access
4 Citations
2,756 Views
11 Pages

Comparison of Safety of Different Vaccine Boosters Following Two-Dose Inactivated Vaccines: A Parallel Controlled Prospective Study

  • Zhi-Qiang Lin,
  • Jiang-Nan Wu,
  • Rong-Dong Huang,
  • Fang-Qin Xie,
  • Jun-Rong Li,
  • Kui-Cheng Zheng and
  • Dong-Juan Zhang

15 April 2022

A vaccine booster to maintain high antibody levels and provide effective protection against COVID-19 has been recommended. However, little is known about the safety of a booster for different vaccines. We conducted a parallel controlled prospective s...

(This article belongs to the Special Issue Assessment of Post-COVID-19 Complications and Vaccination Efficacy)
  • Article
  • Open Access
10 Citations
4,278 Views
26 Pages

Adjuvant Curdlan Contributes to Immunization against Cryptococcus gattii Infection in a Mouse Strain-Specific Manner

  • Patrícia Kellen Martins Oliveira-Brito,
  • Gabriela Yamazaki de Campos,
  • Júlia Garcia Guimarães,
  • Letícia Serafim da Costa,
  • Edanielle Silva de Moura,
  • Javier Emílio Lazo-Chica,
  • Maria Cristina Roque-Barreira and
  • Thiago Aparecido da Silva

15 April 2022

The low efficacy and side effects associated with antifungal agents have highlighted the importance of developing immunotherapeutic approaches to treat Cryptococcus gattii infection. We developed an immunization strategy that uses selective Dectin-1...

(This article belongs to the Special Issue Vaccine Adjuvants Research)
  • Brief Report
  • Open Access
5 Citations
3,085 Views
7 Pages

The Role of COVID-19 Vaccinal Status in Admitted Children during OMICRON Variant Circulation in Rio de Janeiro, City—Preliminary Report

  • André Ricardo Araujo da Silva,
  • Bernardo Rodrigues Rosa de Carvalho,
  • Monica del Monaco Esteves,
  • Cristiane Henriques Teixeira and
  • Cristina Vieira Souza

15 April 2022

Objective: To evaluate COVID-19 vaccination status in admitted children in 2020–2021 and during the OMICRON variant circulation (2022), a period when children older than 12 years of age had received two doses of COVID-19 vaccines. Design: An observat...

(This article belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
  • Article
  • Open Access
12 Citations
4,084 Views
9 Pages

Assessment of Seroconversion after SARS-CoV-2 Vaccination in Patients with Lung Cancer

  • Ioannis P. Trontzas,
  • Ioannis Vathiotis,
  • Christina Economidou,
  • Ioulia Petridou,
  • Georgia Gomatou,
  • Maria Grammoustianou,
  • Ioannis Tsamis,
  • Nikolaos Syrigos,
  • Maximilian Anagnostakis and
  • Ekaterini Syrigou
  • + 4 authors

15 April 2022

Background: SARS-CoV-2 mortality rates are significantly higher in patients with lung cancer compared with the general population. However, little is known on their immunization status after vaccination. Methods: To evaluate the humoral response (ser...

(This article belongs to the Special Issue Oncology in the Era of SARS-CoV-2)
  • Review
  • Open Access
16 Citations
6,536 Views
11 Pages

14 April 2022

For more than a century, epidemic meningococcal disease mainly caused by serogroup A Neisseria meningitidis has been an important public health problem in sub-Saharan Africa. To address this problem, an affordable meningococcal serogroup A conjugate...

(This article belongs to the Special Issue Vaccine Efficacy and Vaccine Effectiveness)
  • Article
  • Open Access
5 Citations
3,550 Views
16 Pages

The Immunomodulatory Functions of Various CpG Oligodeoxynucleotideson CEF Cells and H9N2 Subtype Avian Influenza Virus Vaccination

  • Chenfei Li,
  • Xiangyu Huang,
  • Jiaxi Cai,
  • Anran Lu,
  • Shanshan Hao,
  • Ze Zhang,
  • Haifeng Sun and
  • Xiuli Feng

14 April 2022

CpG oligodeoxynucleotides (CpG ODN) present adjuvant activities for antigen proteins, which can induce humoral and cellular immune responses to antigens. However, the immunomodulatory functions of CpG ODNs with different sequences are very different....

  • Article
  • Open Access
2 Citations
4,158 Views
21 Pages

Mycobacterium bovis Wild-Type BCG or Recombinant BCG Secreting Murine IL-18 (rBCG/IL-18) Strains in Driving Immune Responses in Immunocompetent or Immunosuppressed Mice

  • Marek Fol,
  • Marcin Włodarczyk,
  • Magdalena Kowalewicz-Kulbat,
  • Magdalena Druszczyńska,
  • Krzysztof T. Krawczyk,
  • Sebastian Wawrocki,
  • Wiesława Rudnicka and
  • Magdalena Chmiela

14 April 2022

Mycobacterium tuberculosis infections remain a global health problem in immunosuppressed patients. The effectiveness of BCG (Bacillus Calmette–Guérin), an anti-tuberculosis vaccine, is unsatisfactory. Finding a new vaccine candidate is a...

(This article belongs to the Special Issue Immunity and Vaccination against Bacterial Infections)
  • Feature Paper
  • Review
  • Open Access
15 Citations
5,775 Views
28 Pages

14 April 2022

A significant part of the world population has been affected by the devastating SARS-CoV-2 infection. It has deleterious effects on mental and physical health and global economic conditions. Evidence suggests that the pathogenesis of SARS-CoV-2 infec...

(This article belongs to the Section COVID-19 Vaccines and Vaccination)
  • Brief Report
  • Open Access
3 Citations
2,658 Views
9 Pages

Prolonged Protective Immunity Induced by Mild SARS-CoV-2 Infection of K18-hACE2 Mice

  • Liat Bar-On,
  • Moshe Aftalion,
  • Efi Makdasi,
  • David Gur,
  • Ron Alcalay,
  • Hila Cohen,
  • Adi Beth-Din,
  • Ronit Rosenfeld,
  • Hagit Achdout and
  • Ofer Cohen
  • + 3 authors

14 April 2022

Longevity of the immune response following viral exposure is an essential aspect of SARS-CoV-2 infection. Mild SARS-CoV-2 infection of K18-hACE2 mice was implemented for evaluating the mounting and longevity of a specific memory immune response. We s...

(This article belongs to the Special Issue Feature Papers of Pathogens-Host Immune Interface)
  • Article
  • Open Access
8 Citations
4,092 Views
16 Pages

Transcriptomics of Acute DENV-Specific CD8+ T Cells Does Not Support Qualitative Differences as Drivers of Disease Severity

  • Alba Grifoni,
  • Hannah Voic,
  • Esther Dawen Yu,
  • Jose Mateus,
  • Kai Mei Yan Fung,
  • Alice Wang,
  • Grégory Seumois,
  • Aruna D. De Silva,
  • Rashika Tennekon and
  • Alessandro Sette
  • + 9 authors

14 April 2022

While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of DENV infection remains controversial, and it has...

(This article belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
  • Case Report
  • Open Access
9 Citations
5,160 Views
6 Pages

COVID Vaccine-Associated Myocarditis in Adolescent Siblings: Does It Run in the Family?

  • Julia Moosmann,
  • Thomas Gentles,
  • Christopher Occleshaw and
  • Bryan Mitchelson

14 April 2022

The development of myocarditis after receiving messenger RNA vaccination against COVID-19 is well documented, particularly in adolescent and young adult males. We report a case of vaccine-associated myocarditis in adolescent brothers following their...

  • Article
  • Open Access
22 Citations
4,273 Views
14 Pages

COVID-19 Vaccine Hesitancy among Arab Americans

  • Mira H. Kheil,
  • Deepti Jain,
  • Jamil Jomaa,
  • Brandon Askar,
  • Yasmeen Alcodray,
  • Shatha Wahbi,
  • Salar Brikho,
  • Ali Kadouh,
  • Deanna Harajli and
  • Rouba Ali-Fehmi
  • + 16 authors

14 April 2022

(1) Background: Coronavirus disease-2019 (COVID-19) vaccines have a significant impact on reducing morbidity and mortality from infection. However, vaccine hesitancy remains an obstacle in combating the pandemic. The Arab American (AA) population is...

(This article belongs to the Special Issue Vaccine Acceptance and Uptake: Insights from Behavioural and Social Sciences)
  • Article
  • Open Access
14 Citations
3,255 Views
10 Pages

High COVID-19 Vaccine Acceptance among Eye Healthcare Workers in Uganda

  • Juliet Otiti-Sengeri,
  • Omaido Blair Andrew,
  • Rebecca Claire Lusobya,
  • Immaculate Atukunda,
  • Caroline Nalukenge,
  • Abubakar Kalinaki,
  • John Mukisa,
  • Damalie Nakanjako and
  • Robert Colebunders

14 April 2022

Background: Protecting healthcare workers against COVID-19 disease is crucial, and COVID-19 vaccination is the most effective method to do so. Eye healthcare workers provide routine care in proximity, increasing infection risk, hence their need for f...

  • Review
  • Open Access
43 Citations
11,001 Views
28 Pages

COVID-19 Vaccines: Current and Future Perspectives

  • Luca Soraci,
  • Fabrizia Lattanzio,
  • Giulia Soraci,
  • Maria Elsa Gambuzza,
  • Claudio Pulvirenti,
  • Annalisa Cozza,
  • Andrea Corsonello,
  • Filippo Luciani and
  • Giovanni Rezza

13 April 2022

Currently available vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are highly effective but not able to keep the coronavirus disease 2019 (COVID-19) pandemic completely under control. Alternative R&D strategies are...

(This article belongs to the Special Issue Vaccination Strategies for COVID-19)
  • Review
  • Open Access
41 Citations
10,033 Views
22 Pages

Immunosenescence and Altered Vaccine Efficiency in Older Subjects: A Myth Difficult to Change

  • Tamas Fulop,
  • Anis Larbi,
  • Graham Pawelec,
  • Alan A. Cohen,
  • Guillaume Provost,
  • Abedelouahed Khalil,
  • Guy Lacombe,
  • Serafim Rodrigues,
  • Mathieu Desroches and
  • Jacek M. Witkowski
  • + 2 authors

13 April 2022

Organismal ageing is associated with many physiological changes, including differences in the immune system of most animals. These differences are often considered to be a key cause of age-associated diseases as well as decreased vaccine responses in...

(This article belongs to the Special Issue Knowledge about Vaccines and Vaccination in Older People)
  • Article
  • Open Access
13 Citations
4,298 Views
12 Pages

Trends in HPV and HPV Vaccine Awareness among Gay and Bisexual Males in the U.S

  • Ikechukwu Chidobem,
  • Fan Tian,
  • Esther Ogbuokiri,
  • Francis Mgbodile,
  • Chisom Mgbodile,
  • Tahereh Orouji Jokar,
  • Muhammad Ahsan Shah and
  • Frantz Pierre-Louis

13 April 2022

Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States (US). It is often discussed within the context of women’s sexual health due to its association with cervical cancer. However, HPV is also associat...

  • Review
  • Open Access
93 Citations
7,387 Views
17 Pages

Effect of COVID-19 Pandemic on Influenza Vaccination Intention: A Meta-Analysis and Systematic Review

  • Gwyneth Kong,
  • Nicole-Ann Lim,
  • Yip Han Chin,
  • Yvonne Peng Mei Ng and
  • Zubair Amin

13 April 2022

Poorer outcomes have been reported with COVID-19 and influenza coinfections. As the COVID-19 pandemic rages on, protection against influenza by vaccination is becoming increasingly important. This study examines how COVID-19 has influenced influenza...

(This article belongs to the Special Issue Knowledge and Beliefs on Vaccines)
  • Article
  • Open Access
9 Citations
2,928 Views
10 Pages

Diminished Short- and Long-Term Antibody Response after SARS-CoV-2 Vaccination in Hemodialysis Patients

  • Louise Füessl,
  • Tobias Lau,
  • Isaac Lean,
  • Sandra Hasmann,
  • Bernhard Riedl,
  • Florian M. Arend,
  • Johanna Sorodoc-Otto,
  • Daniela Soreth-Rieke,
  • Marcell Toepfer and
  • Ulf Schönermarck
  • + 12 authors

13 April 2022

Short-term studies have shown an attenuated immune response in hemodialysis patients after COVID-19-vaccination. The present study examines how antibody response is maintained after vaccination against SARS-CoV-2 in a large population of hemodialysis...

(This article belongs to the Special Issue Assessment of Post-COVID-19 Complications and Vaccination Efficacy)
  • Case Report
  • Open Access
3 Citations
10,765 Views
6 Pages

Delayed Cutaneous Adverse Reaction of the AstraZeneca COVID-19 Vaccine in a Breastfed Female Infant: A Coincidence or a Rare Effect?

  • Patrícia Diogo,
  • Gil Correia,
  • João B. Martins,
  • Rui Soares,
  • Paulo J. Palma,
  • João Miguel Santos and
  • Teresa Gonçalves

13 April 2022

The ChAdOx1 nCoV-19 vector vaccine (Vaxzevria, AstraZeneca, Cambridge, UK) was developed at Oxford University and is considered safe for the administration in lactating mothers. Nevertheless, as a novel vaccine, there are gaps in the knowledge regard...

(This article belongs to the Topic Global Analysis of SARS-CoV-2 Serology)
  • Review
  • Open Access
21 Citations
6,372 Views
17 Pages

The Development of Classical Swine Fever Marker Vaccines in Recent Years

  • Fangfang Li,
  • Bingke Li,
  • Xinni Niu,
  • Wenxian Chen,
  • Yuwan Li,
  • Keke Wu,
  • Xiaowen Li,
  • Hongxing Ding,
  • Mingqiu Zhao and
  • Lin Yi
  • + 1 author

13 April 2022

Classical swine fever (CSF) is a severe disease that has caused serious economic losses for the global pig industry and is widely prevalent worldwide. In recent decades, CSF has been effectively controlled through compulsory vaccination with a live C...

  • Article
  • Open Access
10 Citations
2,661 Views
9 Pages

Higher Antibody Concentrations in U.S. Health Care Workers Associated with Greater Reactogenicity Post-Vaccination

  • Jane A. Dickerson,
  • Janet A. Englund,
  • Xing Wang,
  • Julie C. Brown,
  • Danielle M. Zerr,
  • Bonnie Strelitz and
  • Eileen J. Klein

13 April 2022

Multiple factors may be associated with immune responses to SARS-CoV-2 vaccines. Factors potentially related to magnitude and durability of response include age, time, and vaccine reactogenicity. This study analyzed SARS-CoV-2 IgG spike antibody resp...

(This article belongs to the Topic Global Analysis of SARS-CoV-2 Serology)
  • Review
  • Open Access
5 Citations
4,280 Views
13 Pages

Gastric Cancer and Viruses: A Fine Line between Friend or Foe

  • Ahmad Firoz,
  • Hani Mohammed Ali,
  • Suriya Rehman and
  • Irfan A. Rather

13 April 2022

Gastric cancer (GC) is a significant health concern worldwide, with a GLOBOCAN estimate of 1.08 million novel cases in 2020. It is the leading cause of disability-adjusted life years lost to cancer, with the fourth most common cancer in males and the...

  • Brief Report
  • Open Access
4 Citations
3,281 Views
8 Pages

An Economic Comparison of Influenza Vaccines Recommended for Use in Eligible Adults under 65 Years in the United Kingdom

  • Michael Maschio,
  • Michele A. Kohli,
  • Mansoor Ashraf,
  • Michael F. Drummond,
  • Milton C. Weinstein and
  • Joaquin F. Mould-Quevedo

13 April 2022

Background: In the United Kingdom (UK), a cell-based quadrivalent influenza vaccine (QIVc) and a recombinant vaccine (QIVr) are recommended for eligible adults under 65 years. The objective of this analysis was to determine the potential cost-effecti...

(This article belongs to the Section Influenza Virus Vaccines)
  • Article
  • Open Access
14 Citations
3,739 Views
13 Pages

Vaccine Hesitancy towards the COVID-19 Vaccine in a Random National Sample of Belgian Nursing Home Staff Members

  • Marina Digregorio,
  • Pauline Van Ngoc,
  • Simon Delogne,
  • Eline Meyers,
  • Ellen Deschepper,
  • Els Duysburgh,
  • Liselore De Rop,
  • Tine De Burghgraeve,
  • Anja Coen and
  • Beatrice Scholtes
  • + 6 authors

12 April 2022

In Belgium, nursing home staff (NHS) and residents were prioritised for COVID-19 vaccination. However, vaccine hesitancy may have impacted vaccination rates. In this study, a random stratified sample of NHS (N = 1142), vaccinated and unvaccinated, co...

(This article belongs to the Section Vaccines and Public Health)
  • Article
  • Open Access
8 Citations
3,642 Views
8 Pages

SARS-CoV-2 Vaccine-Induced Immune Thrombotic Thrombocytopenia with Venous Thrombosis, Pulmonary Embolism, and Adrenal Haemorrhage: A Case Report with Literature Review

  • Hauke Christian Tews,
  • Sarah M. Driendl,
  • Melanie Kandulski,
  • Christa Buechler,
  • Peter Heiss,
  • Petra Stöckert,
  • Klaus Heissner,
  • Michael G. Paulus,
  • Claudia Kunst and
  • Stephan Schmid
  • + 1 author

12 April 2022

Vaccine-induced immune thrombotic thrombocytopenia (VITT) with venous thrombosis is a rare complication of SARS-CoV-2 vaccination with ChAdOx1 (AstraZeneca) and AD26.COV2.S (Johnson & Johnson, New Brunswick, NJ, USA) associated with high mortalit...

  • Article
  • Open Access
7 Citations
3,433 Views
13 Pages

Motivation for Vaccination against COVID-19 in Persons Aged between 18 and 60 Years at a Population-Based Vaccination Site in Manresa (Spain)

  • Glòria Sauch Valmaña,
  • Aïna Fuster-Casanovas,
  • Anna Ramírez-Morros,
  • Berta Rodoreda Pallàs,
  • Josep Vidal-Alaball,
  • Anna Ruiz-Comellas and
  • Queralt Miró Catalina

12 April 2022

Our purpose was to identify the reasons why members of the population, aged 18–60 years, are vaccinated against COVID-19 at the mass vaccination point in Bages, Spain. This is 1 of 42 provisional spaces outside of health centres which have been...

(This article belongs to the Topic Global Analysis of SARS-CoV-2 Serology)
  • Review
  • Open Access
18 Citations
11,351 Views
20 Pages

Safety of Global SARS-CoV-2 Vaccines, a Meta-Analysis

  • Linyi Chen,
  • Xianming Cai,
  • Tianshuo Zhao,
  • Bingfeng Han,
  • Mingzhu Xie,
  • Jiahao Cui,
  • Jiayu Zhang,
  • Chao Wang,
  • Bei Liu and
  • Fuqiang Cui
  • + 1 author

12 April 2022

(1) Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines were developed in only a short amount of time and were widely distributed. We conducted this meta-analysis to understand the safety of SARS-CoV-2 vaccines. (2) Meth...

(This article belongs to the Special Issue Vaccination Strategies for COVID-19)
  • Article
  • Open Access
7 Citations
5,745 Views
14 Pages

COVID-19 mRNA Vaccines Preserve Immunogenicity after Re-Freezing

  • Santiago Grau,
  • Elena Martín-García,
  • Olivia Ferrández,
  • Raquel Martín,
  • Sonia Tejedor-Vaquero,
  • Ramón Gimeno,
  • Giuliana Magri and
  • Rafael Maldonado

12 April 2022

The massive COVID-19 vaccine purchases made by high-income countries have resulted in important sample losses, mainly due to the complexity of their handling. Here, we evaluated the possibility of preserving the immunogenicity of COVID-19 mRNA vaccin...

(This article belongs to the Section COVID-19 Vaccines and Vaccination)
  • Review
  • Open Access
16 Citations
9,161 Views
13 Pages

12 April 2022

To effectively combat emerging infections and prevent future pandemics, next generation vaccines must be developed quickly, manufactured rapidly, and most critically, administered easily. Next generation vaccines need innovative approaches that preve...

(This article belongs to the Special Issue Technologies for Influenza Vaccines that Provide Increased Speed, Efficacy and Ease of Administration)
  • Review
  • Open Access
68 Citations
14,689 Views
25 Pages

The Importance of Vaccination in the Context of the COVID-19 Pandemic: A Brief Update Regarding the Use of Vaccines

  • Bruna Aparecida Souza Machado,
  • Katharine Valéria Saraiva Hodel,
  • Larissa Moraes dos Santos Fonseca,
  • Vinícius Couto Pires,
  • Luis Alberto Brêda Mascarenhas,
  • Leone Peter Correia da Silva Andrade,
  • Marcelo Albano Moret and
  • Roberto Badaró

12 April 2022

The COVID-19 pandemic has led the world to undertake the largest vaccination campaign in human history. In record time, unprecedented scientific and governmental efforts have resulted in the acquisition of immunizers utilizing different technologies...

(This article belongs to the Special Issue COVID-19 Vaccination, Role of Vaccines and Global Health)
  • Article
  • Open Access
6 Citations
6,587 Views
9 Pages

Risk Analysis by Age on the Burden of Meningococcal Disease in Spain

  • Irene Rivero-Calle,
  • Peter Francis Raguindin,
  • Jacobo Pardo-Seco and
  • Federico Martinon-Torres

12 April 2022

We conducted an age-based risk analysis of meningococcal disease in Spain to provide prospects on a rational vaccine schedule in pediatrics. We used the National Hospital Registry to estimate meningococcal hospitalization rate. Population census for...

(This article belongs to the Special Issue Feature Papers of Epidemiology and Vaccines)
  • Review
  • Open Access
11 Citations
4,708 Views
12 Pages

Global Pandemic Preparedness: Optimizing Our Capabilities and the Influenza Experience

  • Steven Rockman,
  • Beverly Taylor,
  • John W. McCauley,
  • Ian G. Barr,
  • Ray Longstaff and
  • Ranbir Bahra

12 April 2022

The coronavirus disease 2019 (COVID-19) pandemic has prompted rapid investigation and deployment of vaccine platforms never before used to combat human disease. The severe impact on the health system and the high economic cost of non-pharmaceutical i...

(This article belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
  • Article
  • Open Access
16 Citations
9,168 Views
13 Pages

Shoulder Injury Related to COVID-19 Vaccine Administration: A Case Series

  • Korakot Maliwankul,
  • Pattira Boonsri,
  • Prapakorn Klabklay and
  • Chaiwat Chuaychoosakoon

12 April 2022

Background: A shoulder injury related to vaccine administration (SIRVA) is a vaccination complication that can affect daily life activities. To date, there have been no case series of patients diagnosed as SIRVA following a COVID-19 vaccination. We o...

(This article belongs to the Special Issue Vaccination Strategies for COVID-19)
  • Review
  • Open Access
15 Citations
4,604 Views
23 Pages

Vaccine Design against Chagas Disease Focused on the Use of Nucleic Acids

  • Edio Maldonado,
  • Sebastian Morales-Pison,
  • Fabiola Urbina and
  • Aldo Solari

12 April 2022

Chagas disease is caused by the protozoan Trypanosoma cruzi and is endemic to Central and South America. However, it has spread around the world and affects several million people. Treatment with currently available drugs cause several side effects a...

(This article belongs to the Special Issue Nucleic Acid Vaccine)
  • Article
  • Open Access
7 Citations
3,670 Views
12 Pages

Safety and Immunogenicity of COVID-19 BBIBP-CorV Vaccine in Children 3–12 Years Old

  • Khaled Greish,
  • Abdulla Alawadhi,
  • Ahmed Jaradat,
  • Amer Almarabheh,
  • Marwa AlMadhi,
  • Jaleela Jawad,
  • Basma Alsaffar,
  • Ejlal Alalawi,
  • Adel Alsayyad and
  • Manaf Al Qahtani
  • + 4 authors

11 April 2022

Background and Objectives: In the current COVID-19 pandemic, children below the age of 12 could manifest COVID-19 symptoms and serve as a reservoir for the virus in the community. The present study was conducted to evaluate the reactogenicity, and im...

  • Article
  • Open Access
12 Citations
6,843 Views
9 Pages

Impact of Moderna mRNA-1273 Booster Vaccine on Fully Vaccinated High-Risk Chronic Dialysis Patients after Loss of Humoral Response

  • Sammy Patyna,
  • Timon Eckes,
  • Benjamin F. Koch,
  • Stephan Sudowe,
  • Anke Oftring,
  • Niko Kohmer,
  • Holger F. Rabenau,
  • Sandra Ciesek,
  • Despina Avaniadi and
  • Christoph Betz
  • + 3 authors

11 April 2022

The long-term effect of protection by two doses of SARS-CoV-2 vaccination in patients receiving chronic intermittent hemodialysis (CIHD) is an urging question. We investigated the humoral and cellular immune response of 42 CIHD patients who had recei...

  • Article
  • Open Access
8 Citations
3,478 Views
14 Pages

Transdermal Immunization with Microparticulate RSV-F Virus-like Particles Elicits Robust Immunity

  • Sucheta D’Sa,
  • Kimberly Braz Gomes,
  • Grace Lovia Allotey-Babington,
  • Cemil Boyoglu,
  • Sang-Moo Kang and
  • Martin J. D’Souza

10 April 2022

No approved vaccines against respiratory syncytial virus (RSV) infections exist to date, due to challenges arising during vaccine development. There is an unmet need to explore novel approaches and a universal strategy to prevent RSV infections. Prev...

(This article belongs to the Special Issue Development of Vaccines Based on Virus-Like Particles-2nd Edition)

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Vaccines - ISSN 2076-393X