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Article

Trends in COVID-19 Vaccination Intent, Determinants and Reasons for Vaccine Hesitancy: Results from Repeated Cross-Sectional Surveys in the Adult General Population of Greece during November 2020–June 2021

1
Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece
2
4th Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece
*
Author to whom correspondence should be addressed.
Academic Editor: Giuseppe La Torre
Vaccines 2022, 10(3), 470; https://doi.org/10.3390/vaccines10030470
Received: 3 March 2022 / Revised: 16 March 2022 / Accepted: 17 March 2022 / Published: 18 March 2022
(This article belongs to the Special Issue Feature Papers of Epidemiology and Vaccines)
Vaccine hesitancy is a major barrier to achieving large-scale COVID-19 vaccination. We report trends in vaccination intention and associated determinants from surveys in the adult general population in Greece. Four cross-sectional phone surveys were conducted in November 2020 and February, April and May 2021 on nationally representative samples of adults in Greece. Multinomial logistic regression was used on the combined data of the surveys to evaluate independent predictors of vaccination unwillingness/uncertainty. Vaccination intention increased from 67.6% in November 2020 to 84.8% in May 2021. Individuals aged 65 years or older were more willing to be vaccinated (May 2021: 92.9% vs. 79.5% in 18–39 years, p < 0.001) but between age-groups differences decreased over time. Vaccination intention increased substantially in both men and women, though earlier among men, and was higher in individuals with prograduate education (May 2021: 91.3% vs. 84.0% up to junior high). From multivariable analysis, unwillingness and/or uncertainty to be vaccinated was associated with younger age, female gender (in particular in the April 2021 survey), lower educational level and living with a child ≤12 years old. Among those with vaccine hesitancy, concerns about vaccine effectiveness declined over time (21.6% in November 2020 vs. 9.6% in May 2021, p = 0.014) and were reported more often by men; safety concerns remained stable over time (66.3% in November 2020 vs. 62.1% in May 2021, p = 0.658) and were reported more often by women. In conclusion, vaccination intention increased substantially over time. Tailored communication is needed to address vaccine hesitancy and concerns regarding vaccine safety. View Full-Text
Keywords: COVID-19; vaccination intention; vaccination hesitancy; repeated cross-sectional surveys COVID-19; vaccination intention; vaccination hesitancy; repeated cross-sectional surveys
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MDPI and ACS Style

Sypsa, V.; Roussos, S.; Engeli, V.; Paraskevis, D.; Tsiodras, S.; Hatzakis, A. Trends in COVID-19 Vaccination Intent, Determinants and Reasons for Vaccine Hesitancy: Results from Repeated Cross-Sectional Surveys in the Adult General Population of Greece during November 2020–June 2021. Vaccines 2022, 10, 470. https://doi.org/10.3390/vaccines10030470

AMA Style

Sypsa V, Roussos S, Engeli V, Paraskevis D, Tsiodras S, Hatzakis A. Trends in COVID-19 Vaccination Intent, Determinants and Reasons for Vaccine Hesitancy: Results from Repeated Cross-Sectional Surveys in the Adult General Population of Greece during November 2020–June 2021. Vaccines. 2022; 10(3):470. https://doi.org/10.3390/vaccines10030470

Chicago/Turabian Style

Sypsa, Vana, Sotirios Roussos, Vasiliki Engeli, Dimitrios Paraskevis, Sotirios Tsiodras, and Angelos Hatzakis. 2022. "Trends in COVID-19 Vaccination Intent, Determinants and Reasons for Vaccine Hesitancy: Results from Repeated Cross-Sectional Surveys in the Adult General Population of Greece during November 2020–June 2021" Vaccines 10, no. 3: 470. https://doi.org/10.3390/vaccines10030470

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