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Brain Sciences, Volume 10, Issue 7

2020 July - 63 articles

Cover Story: Sleep plays a major role in the neurocognitive development of children, and cognitive impairment is frequent in pediatric cancer, as well as in children who have survived cancer. Pediatric tumors are also often associated with sleep disorders. However, the relationship between sleep disorders, neurodevelopmental disorders, and pediatric cancer is still largely unexplored. Pediatric cancer can be a cause of neurodevelopmental disorders or occur as a comorbid condition in children with neurodevelopmental disorders. In turn, sleep disorders have a particular role in children with cancer and neurodevelopmental disorders. An in-depth knowledge and correct management of sleep disorders can improve the health and quality of life of children with cancer and of their families. View this paper
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Articles (63)

  • Article
  • Open Access
28 Citations
7,984 Views
9 Pages

The Effect of Inquiry-Based Stress Reduction on Teacher Burnout: A Controlled Trial

  • Lia Schnaider-Levi,
  • Ariel B. Ganz,
  • Keren Zafrani,
  • Zehavit Goldman,
  • Inbal Mitnik,
  • Benjamin Rolnik and
  • Shahar Lev-Ari

Burnout is a well-known phenomenon with significant social, biological and economic costs. In particular, teacher burnout is associated with unfavorable mental health outcomes and economic costs due to reduced hours and teacher turnover. This study i...

  • Article
  • Open Access
37 Citations
5,113 Views
17 Pages

Neurophysiological Correlates of a Single Session of Prefrontal tDCS in Patients with Prolonged Disorders of Consciousness: A Pilot Double-Blind Randomized Controlled Study

  • Manon Carrière,
  • Sepehr Mortaheb,
  • Federico Raimondo,
  • Jitka Annen,
  • Alice Barra,
  • Maria C. Binda Fossati,
  • Camille Chatelle,
  • Bertrand Hermann,
  • Géraldine Martens and
  • Aurore Thibaut
  • + 2 authors

Background. Transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (lDLPFC) was reported to promote the recovery of signs of consciousness in some patients in a minimally conscious state (MCS), but its electrophys...

(This article belongs to the Special Issue Recent Advances in the Study of Altered State of Consciousness)
  • Article
  • Open Access
22 Citations
6,955 Views
15 Pages

Mouse Tracking to Explore Motor Inhibition Processes in Go/No-Go and Stop Signal Tasks

  • Viola Benedetti,
  • Gioele Gavazzi,
  • Fabio Giovannelli,
  • Riccardo Bravi,
  • Fiorenza Giganti,
  • Diego Minciacchi,
  • Mario Mascalchi,
  • Massimo Cincotta and
  • Maria Pia Viggiano

Response inhibition relies on both proactive and reactive mechanisms that exert a synergic control on goal-directed actions. It is typically evaluated by the go/no-go (GNG) and the stop signal task (SST) with response recording based on the key-press...

(This article belongs to the Special Issue How Does Motor Inhibitory Control Emerge from the Interplay between Reactive and Proactive Inhibition)
  • Opinion
  • Open Access
51 Citations
13,524 Views
16 Pages

COVID-19: Pain Management in Patients with SARS-CoV-2 Infection—Molecular Mechanisms, Challenges, and Perspectives

  • Sylwester Drożdżal,
  • Jakub Rosik,
  • Kacper Lechowicz,
  • Filip Machaj,
  • Bartosz Szostak,
  • Paweł Majewski,
  • Iwona Rotter and
  • Katarzyna Kotfis

Since the end of 2019, the whole world has been struggling with the pandemic of the new Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Available evidence suggests that pain is a common symptom during Coronavirus Disease 2019 (COVID-19)....

  • Opinion
  • Open Access
41 Citations
6,603 Views
14 Pages

Parkinson’s disease (PD) is a common neurodegenerative disorder; however, well-established biochemical markers have not yet been identified. This review article covers several candidate cerebrospinal fluid (CSF) biomarkers for PD based on the r...

(This article belongs to the Special Issue Cerebrospinal Fluid Biomarkers in Dementia Disorders)
  • Review
  • Open Access
13 Citations
4,833 Views
21 Pages

Transcranial direct current stimulation (tDCS) is accompanied by transient sensations (e.g., tingling, itching, burning), which may affect treatment outcomes or break the blinding of the study protocol. Assessing tolerability and blinding is integral...

  • Article
  • Open Access
29 Citations
6,948 Views
13 Pages

Various studies have shown that Alzheimer’s disease (AD) is associated with an impairment of inhibitory control, although we do not have a comprehensive understanding of the associated cognitive processes. The ability to engage and disengage at...

(This article belongs to the Special Issue Visual Attention-Related Processing: Perspectives from Ageing, Cognitive Decline and Dementia)
  • Article
  • Open Access
17 Citations
4,665 Views
17 Pages

Astroglia-Derived BDNF and MSK-1 Mediate Experience- and Diet-Dependent Synaptic Plasticity

  • Ulyana Lalo,
  • Alexander Bogdanov,
  • Guy W. Moss and
  • Yuriy Pankratov

Experience- and diet-dependent regulation of synaptic plasticity can underlie beneficial effects of active lifestyle on the aging brain. Our previous results demonstrate a key role for brain-derived neurotrophic factor (BDNF) and MSK1 kinase in exper...

(This article belongs to the Section Neuroglia)
  • Article
  • Open Access
33 Citations
5,576 Views
20 Pages

Domain Mapping and Deep Learning from Multiple MRI Clinical Datasets for Prediction of Molecular Subtypes in Low Grade Gliomas

  • Muhaddisa Barat Ali,
  • Irene Yu-Hua Gu,
  • Mitchel S. Berger,
  • Johan Pallud,
  • Derek Southwell,
  • Georg Widhalm,
  • Alexandre Roux,
  • Tomás Gomez Vecchio and
  • Asgeir Store Jakola

Brain tumors, such as low grade gliomas (LGG), are molecularly classified which require the surgical collection of tissue samples. The pre-surgical or non-operative identification of LGG molecular type could improve patient counseling and treatment d...

(This article belongs to the Section Neurotechnology and Neuroimaging)
  • Article
  • Open Access
13 Citations
7,246 Views
19 Pages

Background: Gulf War Illness (GWI) and Chronic Fatigue Syndrome (CFS) are two debilitating disorders that share similar symptoms of chronic pain, fatigue, and exertional exhaustion after exercise. Many physicians continue to believe that both are psy...

(This article belongs to the Special Issue Human Brain Dynamics: Latest Advances and Prospects)
  • Article
  • Open Access
30 Citations
8,247 Views
20 Pages

Palmitoylethanolamide is a nutraceutical compound naturally produced in many plants and animal source foods, but the natural form is poorly water-soluble. It has demonstrated an anti-inflammatory role as a neuroprotective mediator, acting on several...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Article
  • Open Access
18 Citations
7,682 Views
14 Pages

Impact of Aquatic Exercise on Respiratory Outcomes and Functional Activities in Children with Neuromuscular Disorders: Findings from an Open-Label and Prospective Preliminary Pilot Study

  • Marta Huguet-Rodríguez,
  • José Luis Arias-Buría,
  • Belén Huguet-Rodríguez,
  • Rocío Blanco-Barrero,
  • Daniel Braña-Sirgo and
  • Javier Güeita-Rodríguez

Neuromuscular disorders (NMD) lead to the progressive loss of motor and respiratory functions and a decline in daily activities and participation. We aimed to evaluate respiratory changes and functional outcomes in children attending an aquatic thera...

(This article belongs to the Section Developmental Neuroscience)
  • Article
  • Open Access
10 Citations
6,106 Views
12 Pages

“No Pain No Gain”: Evidence from a Parcel-Wise Brain Morphometry Study on the Volitional Quality of Elite Athletes

  • Gaoxia Wei,
  • Ruoguang Si,
  • Youfa Li,
  • Ying Yao,
  • Lizhen Chen,
  • Shu Zhang,
  • Tao Huang,
  • Liye Zou,
  • Chunxiao Li and
  • Stephane Perrey

Volition is described as a psychological construct with great emphasis on the sense of agency. During volitional behavior, an individual always presents a volitional quality, an intrapersonal trait for dealing with adverse circumstances, which determ...

(This article belongs to the Special Issue Studying Brain Activity in Sports Performance)
  • Article
  • Open Access
24 Citations
6,198 Views
16 Pages

Concentrations of Essential Trace Metals in the Brain of Animal Species—A Comparative Study

  • Chiara Alessia DeBenedictis,
  • Andrea Raab,
  • Ellen Ducie,
  • Shauna Howley,
  • Joerg Feldmann and
  • Andreas Martin Grabrucker

The essential trace metals iron, zinc, and copper have a significant physiological role in healthy brain development and function. Especially zinc is important for neurogenesis, synaptogenesis, synaptic transmission and plasticity, and neurite outgro...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Article
  • Open Access
13 Citations
5,352 Views
12 Pages

Over time, the view that creativity is embodied has emerged. In order to explore if visual creativity is supported by embodied mechanisms, the simulation approach was used as a framework of reference. The idea that visual creativity relies on mental...

(This article belongs to the Special Issue The Role of Body in Brain Plasticity)
  • Opinion
  • Open Access
8 Citations
4,899 Views
11 Pages

Deciphering the Invdupdel(8p) Genotype–Phenotype Correlation: Our Opinion

  • Manuela Lo Bianco,
  • Davide Vecchio,
  • Tiziana A. Timpanaro,
  • Alessia Arena,
  • Marina Macchiaiolo,
  • Andrea Bartuli,
  • Laura Sciuto,
  • Santiago Presti,
  • Sarah Sciuto and
  • Piero Pavone
  • + 4 authors

The 8p inverted duplication/deletion is a rare chromosomal rearrangement clinically featuring neurodevelopmental delay, mild to severe cognitive impairment, heart congenital defects and brain abnormalities. Patients affected also present typical faci...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Article
  • Open Access
32 Citations
5,918 Views
13 Pages

Perfusion and Metabolic Neuromonitoring during Ventricular Taps in Infants with Post-Hemorrhagic Ventricular Dilatation

  • Ajay Rajaram,
  • Lawrence C. M. Yip,
  • Daniel Milej,
  • Marianne Suwalski,
  • Matthew Kewin,
  • Marcus Lo,
  • Jeffrey J. L. Carson,
  • Victor Han,
  • Soume Bhattacharya and
  • Keith St. Lawrence
  • + 2 authors

Post-hemorrhagic ventricular dilatation (PHVD) is characterized by a build-up of cerebral spinal fluid (CSF) in the ventricles, which increases intracranial pressure and compresses brain tissue. Clinical interventions (i.e., ventricular taps, VT) wor...

(This article belongs to the Section Neurotechnology and Neuroimaging)
  • Article
  • Open Access
9 Citations
4,657 Views
15 Pages

A Multiple N-Glucosylated Peptide Epitope Efficiently Detecting Antibodies in Multiple Sclerosis

  • Francesca Nuti,
  • Feliciana Real Fernandez,
  • Giuseppina Sabatino,
  • Elisa Peroni,
  • Barbara Mulinacci,
  • Ilaria Paolini,
  • Margherita Di Pisa,
  • Caterina Tiberi,
  • Francesco Lolli and
  • Anna Maria Papini
  • + 4 authors

Diagnostics of Multiple Sclerosis (MS) are essentially based on the gold standard magnetic resonance imaging. Few alternative simple assays are available to follow up disease activity. Considering that the disease can remain elusive for years, identi...

(This article belongs to the Special Issue Advances in Multiple Sclerosis Research—Series I)
  • Opinion
  • Open Access
15 Citations
7,252 Views
13 Pages

During the last two decades, esports, a highly competitive sporting activity, has gained increasing popularity. Both performance and competition in esports require players to have fine motor skills and physical and cognitive abilities in controlling...

  • Article
  • Open Access
38 Citations
5,806 Views
17 Pages

Sex-Specific Effects of Early Life Stress on Brain Mitochondrial Function, Monoamine Levels and Neuroinflammation

  • Héctor González-Pardo,
  • Jorge L. Arias,
  • Eneritz Gómez-Lázaro,
  • Isabel López Taboada and
  • Nélida M. Conejo

Sex differences have been reported in the susceptibility to early life stress and its neurobiological correlates in humans and experimental animals. However, most of the current research with animal models of early stress has been performed mainly in...

(This article belongs to the Special Issue The Role of Stress and Glucocorticoids in Learning and Memory)
  • Article
  • Open Access
10 Citations
5,966 Views
19 Pages

Explaining Age at Autism Spectrum Diagnosis in Children with Migrant and Non-Migrant Background in Austria

  • Patricia Garcia Primo,
  • Christoph Weber,
  • Manuel Posada de la Paz,
  • Johannes Fellinger,
  • Anna Dirmhirn and
  • Daniel Holzinger

This study explored (i) differences in age at Autism Spectrum Disorder (ASD) diagnosis between children with and without a migrant background in the main diagnostic centre for ASD in Upper Austria (ii) factors related to the age at diagnosis and (iii...

(This article belongs to the Special Issue Advances in Autism Research)
  • Review
  • Open Access
19 Citations
6,210 Views
13 Pages

It is commonly accepted that mitochondria represent a major source of free radicals following acute brain injury or during the progression of neurodegenerative diseases. The levels of reactive oxygen species (ROS) in cells are determined by two oppos...

(This article belongs to the Special Issue Mitochondria as Therapeutic Target for Acute Brain Pathologies)
  • Case Report
  • Open Access
5 Citations
4,160 Views
6 Pages

Treatment of Dystonia Using Trihexyphenidyl in Costello Syndrome

  • Domenico M. Romeo,
  • Alessandro Specchia,
  • Alfonso Fasano,
  • Chiara Leoni,
  • Roberta Onesimo,
  • Claudia Brogna,
  • Stefania Veltri and
  • Giuseppe Zampino

Costello syndrome (CS), a rare syndrome with multisystemic involvement inherited as a dominant trait, is characterized by developmental delay, coarse facial appearance, cardiac defects including hypertrophic cardiomyopathy, skin abnormalities, brain...

(This article belongs to the Section Developmental Neuroscience)
  • Article
  • Open Access
6 Citations
6,451 Views
21 Pages

The wrist extensors demonstrate an earlier fatigue onset than the wrist flexors. However, it is currently unclear whether fatigue induces unique changes in muscle activity or corticospinal excitability between these muscle groups. The purpose of this...

(This article belongs to the Special Issue Brain Plasticity and Motor Control—Series II)
  • Article
  • Open Access
9 Citations
4,579 Views
9 Pages

In visual search, participants can incidentally learn spatial target-distractor configurations, leading to shorter search times for repeated compared to novel configurations. Usually, this is tested within the limited visual field provided by a compu...

(This article belongs to the Special Issue Visual Search in (Virtual) Reality)
  • Article
  • Open Access
10 Citations
4,298 Views
9 Pages

Ictal Asystole in Drug-Resistant Focal Epilepsy: Two Decades of Experience from an Epilepsy Monitoring Unit

  • Sara Casciato,
  • Pier Paolo Quarato,
  • Addolorata Mascia,
  • Alfredo D’Aniello,
  • Vincenzo Esposito,
  • Roberta Morace,
  • Luigi Pavone,
  • Carlo Di Bonaventura,
  • Mario Tombini and
  • Giancarlo Di Gennaro
  • + 1 author

Background: Ictal asystole (IA) is a rare event observed in people with epilepsy (PwE). Clinical and IA video-electroencephalographic findings may be helpful in screening for high-risk subjects. Methods: From all PwE undergoing video-EEG for presurgi...

(This article belongs to the Special Issue Advances in Epilepsy)
  • Article
  • Open Access
26 Citations
9,596 Views
19 Pages

“Mom Let’s Go to the Dentist!” Preliminary Feasibility of a Tailored Dental Intervention for Children with Autism Spectrum Disorder in the Italian Public Health Service

  • Antonio Narzisi,
  • Mariasole Bondioli,
  • Francesca Pardossi,
  • Lucia Billeci,
  • Maria Claudia Buzzi,
  • Marina Buzzi,
  • Martina Pinzino,
  • Caterina Senette,
  • Valentina Semucci and
  • Susanna Pelagatti
  • + 4 authors

Children with autism spectrum disorder (ASD) show worse oral health than their peers. Their access to health services is, at present, inadequate: few high-quality interventions have been designed and implemented to improve their care procedures so fa...

(This article belongs to the Special Issue Advances in Autism Research)
  • Case Report
  • Open Access
5 Citations
8,774 Views
6 Pages

Occasionally, acute ischemic stroke can be difficult to differentiate from acute intracranial infection. We describe a patient who presented with sudden onset of right hemiparesis and fever. Magnetic resonance imaging (MRI) was consistent with an acu...

(This article belongs to the Section Neurotechnology and Neuroimaging)
  • Review
  • Open Access
58 Citations
18,969 Views
30 Pages

Autism Spectrum Disorders (ASD) are lifelong neurodevelopmental conditions characterized by abnormal social interaction, communication, and behavior. Sleep disturbances represent a common comorbidity in children and adolescents with ASD, with prevale...

(This article belongs to the Section Developmental Neuroscience)
  • Article
  • Open Access
42 Citations
7,038 Views
14 Pages

Silent Speech Decoding Using Spectrogram Features Based on Neuromuscular Activities

  • You Wang,
  • Ming Zhang,
  • RuMeng Wu,
  • Han Gao,
  • Meng Yang,
  • Zhiyuan Luo and
  • Guang Li

Silent speech decoding is a novel application of the Brain–Computer Interface (BCI) based on articulatory neuromuscular activities, reducing difficulties in data acquirement and processing. In this paper, spatial features and decoders that can...

(This article belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)
  • Article
  • Open Access
9 Citations
4,116 Views
15 Pages

Loss of intracellular calcium homeostasis is an established mechanism associated with neuronal dysfunction and status epilepticus. Sequestration of free cytosolic calcium into endoplasmic reticulum by Mg2+/Ca2+ adenosinetriphosphatase (ATPase) is cri...

(This article belongs to the Section Neuroglia)
  • Article
  • Open Access
20 Citations
5,102 Views
18 Pages

Association of Exercise with Inhibitory Control and Prefrontal Brain Activity Under Acute Psychosocial Stress

  • Manuel Mücke,
  • Sebastian Ludyga,
  • Flora Colledge,
  • Uwe Pühse and
  • Markus Gerber

Psychosocial stress has negative effects on cognition in adolescents. The aim of this study was to investigate whether physical exercise can buffer such effects on inhibitory control and associated cortical brain areas. Forty-two male high school stu...

(This article belongs to the Section Developmental Neuroscience)
  • Communication
  • Open Access
20 Citations
5,835 Views
5 Pages

The COVID-19 pandemic has posed a serious challenge for the life and mental health of people with autism spectrum disorder (ASD). COVID-19 sanitary restrictions led to significant changes in the lives of people with ASD, including their routines; sim...

(This article belongs to the Special Issue Advances in Autism Research)
  • Review
  • Open Access
11 Citations
10,306 Views
22 Pages

Brain Opioid Activity and Oxidative Injury: Different Molecular Scenarios Connecting Celiac Disease and Autistic Spectrum Disorder

  • Diana Di Liberto,
  • Antonella D’Anneo,
  • Daniela Carlisi,
  • Sonia Emanuele,
  • Anna De Blasio,
  • Giuseppe Calvaruso,
  • Michela Giuliano and
  • Marianna Lauricella

Celiac Disease (CD) is an immune-mediated disease triggered by the ingestion of wheat gliadin and related prolamins from other cereals, such as barley and rye. Immunity against these cereal-derived proteins is mediated by pro-inflammatory cytokines p...

(This article belongs to the Special Issue Recent Advances in Neurodevelopmental Disorders)
  • Article
  • Open Access
4 Citations
5,140 Views
15 Pages

Sex Differences in Work-Stress Memory Bias and Stress Hormones

  • Laurence Dumont,
  • Marie-France Marin,
  • Sonia J. Lupien and
  • Robert-Paul Juster

Mental health problems related to chronic stress in workers appear to be sex-specific. Psychosocial factors related to work–life balance partly explain these sex differences. In addition, physiological markers of stress can provide critical inf...

(This article belongs to the Special Issue Hormones and Cognition)
  • Article
  • Open Access
10 Citations
4,390 Views
16 Pages

Short-interval intracortical inhibition (SICI) represents an inhibitory phenomenon acting at the cortical level. However, SICI estimation is based on the amplitude of a motor-evoked potential (MEP), which depends on the discharge of spinal motoneuron...

(This article belongs to the Special Issue Transcranial Magnetic Stimulation (TMS): Applications in Clinical and Basic Neuroscience)
  • Article
  • Open Access
3 Citations
5,119 Views
13 Pages

A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team

  • Phoebe Lay,
  • Tapasvini Paralkar,
  • Syed Hadi Ahmed,
  • Minha Ghani,
  • Sara Muneer,
  • Ramsha Jinnah,
  • Carolyn Chen,
  • Jack Zeitz,
  • Alejandra Nitsch and
  • Nico Osier

The advancement of the pediatric traumatic brain injury (TBI) knowledge base requires biospecimens and data from large samples. This study seeks to describe a novel clinical research modality to establish best practices for enrolling a diverse pediat...

(This article belongs to the Special Issue Health Disparities in Traumatic Brain Injury)
  • Review
  • Open Access
26 Citations
7,092 Views
18 Pages

An accumulating body of evidence indicates a tight relationship between the endocrine system and abnormal social behavior. Two evolutionarily conserved hypothalamic peptides, oxytocin and arginine-vasopressin, because of their extensively documented...

(This article belongs to the Special Issue Advances in Autism Research)
  • Article
  • Open Access
2 Citations
4,114 Views
20 Pages

Feasibility Randomized Trial for an Intensive Memory-Focused Training Program for School-Aged Children with Acquired Brain Injury

  • Monica Recla,
  • Erika Molteni,
  • Valentina Manfredi,
  • Filippo Arrigoni,
  • Andrea Nordio,
  • Susanna Galbiati,
  • Valentina Pastore,
  • Marc Modat and
  • Sandra Strazzer

(1) Background: Memory deficits are common sequelae of pediatric Acquired Brain Injury (ABI). Only methods for non-focused cognitive remediation are available to the pediatric field. The aims of this feasibility trial are the description, implementat...

(This article belongs to the Special Issue Mild and Moderate Traumatic Brain Injuries: Diagnosis, Assessment Tools, Management and Factors Influencing Recovery)
  • Article
  • Open Access
5 Citations
4,738 Views
29 Pages

Cortico-Hippocampal Computational Modeling Using Quantum Neural Networks to Simulate Classical Conditioning Paradigms

  • Mustafa Khalid,
  • Jun Wu,
  • Taghreed M. Ali,
  • Thaair Ameen,
  • Ahmed A. Moustafa,
  • Qiuguo Zhu and
  • Rong Xiong

Most existing cortico-hippocampal computational models use different artificial neural network topologies. These conventional approaches, which simulate various biological paradigms, can get slow training and inadequate conditioned responses for two...

(This article belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
  • Article
  • Open Access
4 Citations
3,261 Views
11 Pages

Where Sounds Occur Matters: Context Effects Influence Processing of Salient Vocalisations

  • Atiqah Azhari,
  • Paola Rigo,
  • Marc H. Bornstein and
  • Gianluca Esposito

The social context in which a salient human vocalisation is heard shapes the affective information it conveys. However, few studies have investigated how visual contextual cues lead to differential processing of such vocalisations. The prefrontal cor...

(This article belongs to the Section Behavioral Neuroscience)
  • Article
  • Open Access
7 Citations
4,130 Views
17 Pages

This electrophysiological study investigated the role of the medial olivocochlear (MOC) efferents in listening in noise. Both ears of eleven normal-hearing adult participants were tested. The physiological tests consisted of transient-evoked otoacous...

(This article belongs to the Section Systems Neuroscience)
  • Article
  • Open Access
14 Citations
4,324 Views
13 Pages

Prospective Memory, Sleep, and Age

  • Miranda Occhionero,
  • Lorenzo Tonetti,
  • Marco Fabbri,
  • Michele Boreggiani,
  • Monica Martoni,
  • Sara Giovagnoli and
  • Vincenzo Natale

It is reported that sleep enhances prospective memory (PM), but it remains to be understood whether this influence is moderated by age, since sleep changes across the lifespan. To this end, we performed a retrospective study in a naturalistic setting...

  • Article
  • Open Access
46 Citations
8,155 Views
19 Pages

Effects of Transcranial Magnetic Stimulation Therapy on Evoked and Induced Gamma Oscillations in Children with Autism Spectrum Disorder

  • Manuel F. Casanova,
  • Mohamed Shaban,
  • Mohammed Ghazal,
  • Ayman S. El-Baz,
  • Emily L. Casanova,
  • Ioan Opris and
  • Estate M. Sokhadze

Autism spectrum disorder (ASD) is a behaviorally diagnosed neurodevelopmental condition of unknown pathology. Research suggests that abnormalities of elecltroencephalogram (EEG) gamma oscillations may provide a biomarker of the condition. In this stu...

(This article belongs to the Special Issue Modern Developments in Transcranial Magnetic Stimulation (TMS) –Applications and Perspectives in Clinical Neuroscience)
  • Article
  • Open Access
9 Citations
4,106 Views
14 Pages

Molecular and Cellular Impact of Inflammatory Extracellular Vesicles (EVs) Derived from M1 and M2 Macrophages on Neural Action Potentials

  • Sarah Vakili,
  • Taha Mohseni Ahooyi,
  • Shadan S. Yarandi,
  • Martina Donadoni,
  • Jay Rappaport and
  • Ilker K. Sariyer

Several factors can contribute to neuroinflammatory disorders, such as cytokine and chemokines that are produced and released from peripherally derived immune cells or from locally activated cells such as microglia and perivascular macrophages in the...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Article
  • Open Access
4 Citations
4,245 Views
12 Pages

Neck Pain- and Unsteadiness-Inducing Activities and their Relationship to the Presence, Intensity, Frequency, and Disability of Headaches

  • Daniel Rodríguez-Almagro,
  • Alexander Achalandabaso-Ochoa,
  • Francisco Javier Molina-Ortega,
  • Esteban Obrero-Gaitán,
  • Alfonso Javier Ibáñez-Vera and
  • Rafael Lomas-Vega

(1) Background: Headache is a significant public health problem. Despite the association between headache and neck pain, little is known about the relationships among specific activities that generate neck pain and headache. The aim of this study was...

  • Case Report
  • Open Access
2 Citations
5,773 Views
10 Pages

Celiac Disease Diagnosed in an Older Adult Patient with a Complex Neuropsychiatric Involvement: A Case Report and Review of the Literature

  • Emma Falato,
  • Fioravante Capone,
  • Federico Ranieri,
  • Lucia Florio,
  • Marzia Corbetto,
  • Chiara Taffon,
  • Cinzia Niolu,
  • Giorgio Di Lorenzo and
  • Vincenzo Di Lazzaro

We present a case of celiac disease (CD) diagnosis in a 75-year-old woman with a long-term history of chronic delusional jealousy and a complex neurological involvement. The case describes a very unusual clinical picture, provides some clinical clues...

  • Article
  • Open Access
190 Citations
10,851 Views
19 Pages

State-of-the-Art CNN Optimizer for Brain Tumor Segmentation in Magnetic Resonance Images

  • Muhammad Yaqub,
  • Jinchao Feng,
  • M. Sultan Zia,
  • Kaleem Arshid,
  • Kebin Jia,
  • Zaka Ur Rehman and
  • Atif Mehmood

Brain tumors have become a leading cause of death around the globe. The main reason for this epidemic is the difficulty conducting a timely diagnosis of the tumor. Fortunately, magnetic resonance images (MRI) are utilized to diagnose tumors in most c...

  • Article
  • Open Access
8 Citations
3,730 Views
10 Pages

Atrial Fibrillation on Patients with Vascular Dementia: A Fundamental Target for Correct Management

  • Giovanna Viticchi,
  • Lorenzo Falsetti,
  • Marco Burattini,
  • Vincenzo Zaccone,
  • Laura Buratti,
  • Marco Bartolini,
  • Gianluca Moroncini and
  • Mauro Silvestrini

Background: Atrial fibrillation (AF) is a risk factor for cerebrovascular diseases and vascular dementia (VAD). The aim of this study was to evaluate the effect of the adherence to anticoagulant therapy guidelines in patients with dementia and AF on...

(This article belongs to the Section Neurodegenerative Diseases)
  • Editorial
  • Open Access
16 Citations
4,118 Views
11 Pages

Gender-specific medicine is a discipline that studies the influence of sex and gender on physiology, pathophysiology, and diseases. One example in light of how a genetic-based disease among other diseases, that impact on sex, can be represented by th...

(This article belongs to the Section Molecular and Cellular Neuroscience)

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