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Microorganisms, Volume 11, Issue 12

2023 December - 187 articles

Cover Story: Cutaneous leishmaniasis (CL) is the most common clinical presentation of leishmaniasis, a Neglected Tropical Disease (NTD). While other presentations of leishmaniasis can be fatal, CL is mostly non-lethal and despite its prevalence not a priority for drug treatment. Yet, CL can be disfiguring and cause prolonged suffering in afflicted individuals. Several drugs are currently used to treat leishmaniasis, although they often have harsh side effects and long treatment regimens, and drug resistance is emerging across the globe. In search of novel drug therapies, researchers have been using biochemical and computational techniques for early-stage drug discovery efforts. This review focuses on the substantial yet fragmented progress in drug discovery for CL and highlights the common challenges for researchers. View this paper
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Articles (187)

  • Review
  • Open Access
14 Citations
7,932 Views
25 Pages

Medically Significant Vector-Borne Viral Diseases in Iran

  • Sarah-Jo Paquette,
  • Ayo Yila Simon,
  • Ara XIII,
  • Gary P. Kobinger and
  • Nariman Shahhosseini

Vector-borne viral diseases (VBVDs) continue to pose a considerable public health risk to animals and humans globally. Vectors have integral roles in autochthonous circulation and dissemination of VBVDs worldwide. The interplay of agricultural activi...

  • Review
  • Open Access
9 Citations
5,202 Views
31 Pages

Neisseria meningitidis is commensal of the human pharynx and occasionally invades the host, causing the life-threatening illness invasive meningococcal disease. The meningococcus is a highly diverse and adaptable organism thanks to natural competence...

  • Review
  • Open Access
4 Citations
11,678 Views
25 Pages

Oral Antibiotics for Bacteremia and Infective Endocarditis: Current Evidence and Future Perspectives

  • Gerasimos Eleftheriotis,
  • Markos Marangos,
  • Maria Lagadinou,
  • Sanjay Bhagani and
  • Stelios F. Assimakopoulos

Bacteremia and endocarditis are two clinical syndromes that, for decades, were managed exclusively with parenteral antimicrobials, irrespective of a given patient’s clinical condition, causative pathogen, or its antibiotic susceptibility profil...

  • Article
  • Open Access
5 Citations
1,773 Views
14 Pages

This study investigated the effects of single Fenton and Fenton and UV combined processes on the cracking degree of anaerobic sludge under the same conditions. The optimal experimental conditions were obtained by repeated determination of Fe2+ dosage...

  • Communication
  • Open Access
3 Citations
2,298 Views
11 Pages

Soil Bacterial Diversity Responds to Long-Term Establishment of Perennial Legumes in Warm-Season Grassland at Two Soil Depths

  • Adesuwa Sylvia Erhunmwunse,
  • Victor Alonso Guerra,
  • Jung-Chen Liu,
  • Cheryl L. Mackowiak,
  • Ann Rachel Soffes Blount,
  • José Carlos Batista Dubeux and
  • Hui-Ling Liao

The introduction of rhizoma peanut (RP Arachis glabrata Benth) into bahiagrass (Paspalum notatum Flüggé) may require time to develop stable plant–soil microbe interactions as the microbial legacy of the previous plant comm...

  • Article
  • Open Access
7 Citations
2,797 Views
15 Pages

Cold seeps are highly productive chemosynthetic ecosystems in the deep-sea environment. Although microbial communities affected by methane seepage have been extensively studied in sediments and seawater, there is a lack of investigation of prokaryoti...

  • Article
  • Open Access
3 Citations
2,648 Views
11 Pages

Tigecycline Sensitivity Reduction in Escherichia coli Due to Widely Distributed tet(A) Variants

  • Shan Zhang,
  • Mingquan Cui,
  • Dejun Liu,
  • Bo Fu,
  • Tingxuan Shi,
  • Yang Wang,
  • Chengtao Sun and
  • Congming Wu

Despite scattered studies that have reported mutations in the tet(A) gene potentially linked to tigecycline resistance in clinical pathogens, the detailed function and epidemiology of these tet(A) variants remains limited. In this study, we analyzed...

  • Systematic Review
  • Open Access
12 Citations
2,998 Views
18 Pages

The physiopathology of liver diseases is complex and can be caused by various factors. Bifidobacterium is a bacterial genus commonly found in the human gut microbiome and has been shown to influence the development of different stages of liver diseas...

  • Article
  • Open Access
2 Citations
2,769 Views
19 Pages

Apart from being preventable and treatable, tuberculosis is the deadliest bacterial disease afflicting humankind owing to its ability to evade host defence responses, many of which are controlled by epigenetic mechanisms. Here, we report the temporal...

  • Article
  • Open Access
1 Citations
2,441 Views
15 Pages

Development and Validation of a Highly Sensitive Multiplex Immunoassay for SARS-CoV-2 Humoral Response Monitorization: A Study of the Antibody Response in COVID-19 Patients with Different Clinical Profiles during the First and Second Waves in Cadiz, Spain

  • Lucia Olvera-Collantes,
  • Noelia Moares,
  • Ricardo Fernandez-Cisnal,
  • Juan P. Muñoz-Miranda,
  • Pablo Gonzalez-Garcia,
  • Antonio Gabucio,
  • Carolina Freyre-Carrillo,
  • Juan de Dios Jordan-Chaves,
  • Teresa Trujillo-Soto and
  • Francisco Garcia-Cozar
  • + 5 authors

There is still a long way ahead regarding the COVID-19 pandemic, since emerging waves remain a daunting challenge to the healthcare system. For this reason, the development of new preventive tools and therapeutic strategies to deal with the disease h...

  • Review
  • Open Access
24 Citations
3,806 Views
17 Pages

Rocahepevirus ratti as an Emerging Cause of Acute Hepatitis Worldwide

  • Sara Benavent,
  • Silvia Carlos and
  • Gabriel Reina

The hepatitis E virus (HEV) is a widespread human infection that causes mainly acute infection and can evolve to a chronic manifestation in immunocompromised individuals. In addition to the common strains of hepatitis E virus (HEV-A), known as Paslah...

  • Case Report
  • Open Access
4 Citations
2,337 Views
8 Pages

A Large-Scale Outbreak of Trichinellosis from Infected Wild Boar Meat in Croatia and the Role of Real-Time PCR Assays in Confirming the Source of the Disease

  • Davor Balić,
  • Tomislav Dijanić,
  • Marija Agičić,
  • Josip Barić,
  • Maria Kaltenbrunner,
  • Hrvoje Krajina,
  • Rupert Hochegger,
  • Mario Škrivanko and
  • Karlo Kožul

Background: Trichinellosis in Croatia posed a significant health concern during the 1990s, followed by a notable improvement in the epidemiological situation. However, in 2017, there was a resurgence, with 37 recorded cases in 3 outbreaks and 3 spora...

  • Article
  • Open Access
6 Citations
3,771 Views
20 Pages

Microbial Diversity and Community Structure of Wastewater-Driven Microalgal Biofilms

  • Olga Blifernez-Klassen,
  • Julia Hassa,
  • Diana L. Reinecke,
  • Tobias Busche,
  • Viktor Klassen and
  • Olaf Kruse

Dwindling water sources increase the need for efficient wastewater treatment. Solar-driven algal turf scrubber (ATS) system may remediate wastewater by supporting the development and growth of periphytic microbiomes that function and interact in a hi...

  • Article
  • Open Access
3 Citations
1,950 Views
14 Pages

Enterotoxigenic and Antimicrobic Susceptibility Profile of Staphylococcus aureus Isolates from Fresh Cheese in Croatia

  • Ivana Ljevaković-Musladin,
  • Lidija Kozačinski,
  • Marija Krilanović,
  • Marina Vodnica Martucci,
  • Mato Lakić,
  • Luca Grispoldi and
  • Beniamino T. Cenci-Goga

Certain Staphylococcus aureus strains harbour staphylococcal enterotoxin genes and hence can produce enterotoxin during their growth in food. Therefore, food can be a source of staphylococcal food poisoning, one of the most common food-borne diseases...

  • Article
  • Open Access
1 Citations
2,337 Views
11 Pages

The Presence of Legionella in Water Used for Car Washing: Implications for Public Health

  • Pasqualina Laganà,
  • Alessio Facciolà,
  • Roberta Palermo,
  • Osvalda De Giglio,
  • Santi Antonino Delia and
  • Maria Eufemia Gioffrè

Although today all of the aspects of Legionella are better understood than in the past, in many countries the interest is still mainly focused on healthcare and tourism facilities. Other at-risk areas are less explored, such as those where workers ar...

  • Article
  • Open Access
9 Citations
3,892 Views
14 Pages

Antimicrobial Resistance Profiles of Enterococcus faecium and Enterococcus faecalis Isolated from Healthy Dogs and Cats in South Korea

  • Bo-Youn Moon,
  • Md. Sekendar Ali,
  • Ji-Hyun Choi,
  • Ye-Eun Heo,
  • Yeon-Hee Lee,
  • Hee-Seung Kang,
  • Tae-Sun Kim,
  • Soon-Seek Yoon,
  • Dong-Chan Moon and
  • Suk-Kyung Lim

Enterococcus spp. are typically found in the gastrointestinal tracts of humans and animals. However, they have the potential to produce opportunistic infections that can be transmitted to humans or other animals, along with acquired antibiotic resist...

  • Article
  • Open Access
4 Citations
2,519 Views
16 Pages

Isolation and Evaluation of Streptomyces melanogenes YBS22 with Potential Application for Biocontrol of Rice Blast Disease

  • Luyang Song,
  • Fei Wang,
  • Chuang Liu,
  • Zhengzhe Guan,
  • Mengjiao Wang,
  • Rongrong Zhong,
  • Huijun Xi,
  • Ying Zhao and
  • Caiyi Wen

Plant diseases caused by pathogenic fungi pose a significant threat to agricultural production. This study reports on a strain YBS22 with broad-spectrum antifungal activity that was isolated and identified, and its active metabolites were purified an...

  • Feature Paper
  • Article
  • Open Access
8 Citations
2,250 Views
12 Pages

Sanitisers are widely used in cleaning food-processing facilities, but their continued use may cause an increased resistance of pathogenic bacteria. Several genes have been attributed to the increased sanitiser resistance ability of L. monocytogenes....

  • Review
  • Open Access
34 Citations
10,196 Views
23 Pages

One Health Perspectives on Food Safety in Minimally Processed Vegetables and Fruits: From Farm to Fork

  • Maria Isabel Santos,
  • Madalena Grácio,
  • Mariana Camoesas Silva,
  • Laurentina Pedroso and
  • Ana Lima

While food markets and food production chains are experiencing exponential growth, global attention to food safety is steadily increasing. This is particularly crucial for ready-to-eat products such as fresh-cut salads and fruits, as these items are...

  • Review
  • Open Access
7 Citations
4,490 Views
22 Pages

Methanotrophy is the ability of an organism to capture and utilize the greenhouse gas, methane, as a source of energy-rich carbon. Over the years, significant progress has been made in understanding of mechanisms for methane utilization, mostly in ba...

  • Article
  • Open Access
2 Citations
2,234 Views
13 Pages

The Genomic Characteristics of an Arthritis-Causing Salmonella pullorum

  • Zhiyuan Lu,
  • Jiaqi Huang,
  • Peiyong Li,
  • Mengze Song,
  • Ben Liu,
  • Wenli Tang and
  • Shuhong Sun

Salmonella enterica subsp. enterica serovar Gallinarum biovar pullorum (Salmonella pullorum) is an avian-specific pathogen that has caused considerable economic losses to the poultry industry. High endemicity, poor implementation of hygiene measures,...

  • Review
  • Open Access
3 Citations
4,071 Views
21 Pages

AAV Immunotoxicity: Implications in Anti-HBV Gene Therapy

  • Ridhwaanah Jacobs,
  • Makafui Dennis Dogbey,
  • Njabulo Mnyandu,
  • Keila Neves,
  • Stefan Barth,
  • Patrick Arbuthnot and
  • Mohube Betty Maepa

Hepatitis B virus (HBV) has afflicted humankind for decades and there is still no treatment that can clear the infection. The development of recombinant adeno-associated virus (rAAV)-based gene therapy for HBV infection has become important in recent...

  • Article
  • Open Access
4 Citations
2,612 Views
12 Pages

The ability to sense and direct movement along chemical gradients is known as ‘chemotaxis’ and is a common trait among rhizosphere microorganisms, which are attracted to organic compounds released from plant roots. In response to stress,...

  • Article
  • Open Access
16 Citations
4,215 Views
33 Pages

Bacillus subtilis 26D is a plant growth-promoting endophytic bacteria capable of inducing systemic resistance through the priming mechanism, which includes plant genome reprogramming and the phenomenon of RNA interference (RNAi) and microRNA (miRNAs)...

  • Article
  • Open Access
7 Citations
2,647 Views
21 Pages

Effect of Antimicrobial Use in Conventional Versus Natural Cattle Feedlots on the Microbiome and Resistome

  • Catrione Lee,
  • Rahat Zaheer,
  • Krysty Munns,
  • Devin B. Holman,
  • Gary Van Domselaar,
  • Athanasios Zovoilis and
  • Tim A. McAllister

Antimicrobial use (AMU) in the livestock industry has been associated with increased levels of antimicrobial resistance. Recently, there has been an increase in the number of “natural” feedlots in the beef cattle sector that raise cattle...

  • Article
  • Open Access
11 Citations
3,442 Views
10 Pages

Enterococcus spp. are common bacteria present in the intestinal tracts of animals and are used as fecal indicators in aquatic environments. On the other hand, enterococci are also known as opportunistic pathogens. Elucidating their composition in the...

  • Article
  • Open Access
5 Citations
2,869 Views
15 Pages

Satureja hortensis L. and Calendula officinalis L., Two Romanian Plants, with In Vivo Antiparasitic Potential against Digestive Parasites of Swine

  • Mihai-Horia Băieş,
  • Vlad-Dan Cotuţiu,
  • Marina Spînu,
  • Attila Mathe,
  • Anamaria Cozma-Petruț,
  • Vlad I. Bocǎneţ and
  • Vasile Cozma

Internal parasitic diseases of swine constitute a major welfare and health concern in low-input livestock farming. Due to an increase in chemical resistance, phytotherapeutic remedies have become an alternative for the prophylaxis and therapy of dige...

  • Article
  • Open Access
3 Citations
3,278 Views
29 Pages

Plants influence the abiotic and biotic environment of the rhizosphere, affecting plant performance through plant–soil feedback (PSF). We compared the strength of nutrient and microbe-mediated PSF and its implications for plant performance in d...

  • Article
  • Open Access
7 Citations
2,328 Views
14 Pages

Biodegradation of Cholesterol by Enterococcus faecium YY01

  • Ruimin Yang,
  • Shahbaz Ahmad,
  • Hongyan Liu,
  • Qianqian Xu,
  • Chunhua Yin,
  • Yang Liu,
  • Haiyang Zhang and
  • Hai Yan

Cholesterol (CHOL) is one of the risk factors causing the blockage of the arterial wall, atherosclerosis, coronary heart disease, and other serious cardiovascular diseases. Here, a promising bacterial strain for biodegrading CHOL was successfully iso...

  • Article
  • Open Access
2 Citations
3,700 Views
18 Pages

HLA-DQ2/8 and COVID-19 in Celiac Disease: Boon or Bane

  • Aaron Lerner,
  • Carina Benzvi and
  • Aristo Vojdani

The SARS-CoV-2 pandemic continues to pose a global threat. While its virulence has subsided, it has persisted due to the continual emergence of new mutations. Although many high-risk conditions related to COVID-19 have been identified, the understand...

  • Article
  • Open Access
1 Citations
2,051 Views
17 Pages

This study introduces a groundbreaking approach for the exploration and utilization of electrotrophic acetogens, essential for advancing microbial electrosynthesis systems (MES). Our initial focus was the development of Solid-Phase Electrochemical Is...

  • Communication
  • Open Access
5 Citations
2,310 Views
11 Pages

Synthesis of Silver Nanoparticles Using Aggregatimonas sangjinii F202Z8T and Their Biological Characterization

  • Yong Min Kwon,
  • Eun-Seo Cho,
  • Kyung Woo Kim,
  • Dawoon Chung,
  • Seung Seob Bae,
  • Woon-Jong Yu,
  • Jaoon Young Hwan Kim and
  • Grace Choi

The aim of this study is to describe the general features and eco-friendly biosynthesis of silver nanoparticles (AgNPs) from the marine bacterium Aggregatimonas sangjinii F202Z8T. To the best of our knowledge, no previous study has reported the biosy...

  • Review
  • Open Access
10 Citations
3,149 Views
18 Pages

Influenza A virus (IAV) infections represent a substantial global health challenge and are often accompanied by coinfections involving secondary viruses or bacteria, resulting in increased morbidity and mortality. The clinical impact of coinfections...

  • Article
  • Open Access
9 Citations
3,107 Views
18 Pages

Extracellular Vesicles Released by Leishmania (Leishmania) amazonensis Promastigotes with Distinct Virulence Profile Differently Modulate the Macrophage Functions

  • Rogéria Cristina Zauli,
  • Isabelle Carlos de Souza Perez,
  • Aline Correia Costa de Morais,
  • Ana Carolina Ciaccio,
  • Andrey Sladkevicius Vidal,
  • Rodrigo Pedro Soares,
  • Ana Claudia Torrecilhas,
  • Wagner Luiz Batista and
  • Patricia Xander

Leishmania spp. is the aetiologic agent of leishmaniasis, a disease endemic in several developing countries. The parasite expresses and secretes several virulence factors that subvert the macrophage function and immune response. Extracellular vesicle...

  • Article
  • Open Access
3 Citations
3,153 Views
17 Pages

Comparative Genomic Analysis of Cutibacterium spp. Isolates in Implant-Associated Infections

  • Anja Erbežnik,
  • Andraž Celar Šturm,
  • Katja Strašek Smrdel,
  • Tina Triglav and
  • Polona Maver Vodičar

Bacteria of the genus Cutibacterium are Gram-positive commensals and opportunistic pathogens that represent a major challenge in the diagnosis and treatment of implant-associated infections (IAIs). This study provides insight into the distribution of...

  • Brief Report
  • Open Access
6 Citations
2,490 Views
10 Pages

Draft Genome of Nocardia canadensis sp. nov. Isolated from Petroleum-Hydrocarbon-Contaminated Soil

  • Fahad Alotaibi,
  • Soon-Jae Lee,
  • Zakaria Lahrach,
  • Marc St-Arnaud and
  • Mohamed Hijri

The bacterial strain WB46 was isolated from the rhizosphere of willow plants (Salix purpurea L.) growing in soil contaminated with petroleum hydrocarbons. The strain was subjected to whole-genome shotgun sequencing using Illumina HiSeq. Its draf...

  • Article
  • Open Access
7 Citations
2,993 Views
13 Pages

Older patients with multiple comorbidities often necessitate prolonged hospital stays and antibiotic treatment in the intensive care unit (ICU), leading to a rise in multidrug-resistant organisms like carbapenem-resistant Enterobacteriaceae (CRE). Th...

  • Article
  • Open Access
2 Citations
2,686 Views
16 Pages

Fusobacterium necrophorum, an anaerobic Gram-negative pathogen, causes necrotic cattle infections, impacting livestock health and the US feedlot industry. Antibiotic administration is the mainstay for treating F. necrophorum infections, although resi...

  • Article
  • Open Access
1 Citations
2,137 Views
14 Pages

The Pneumococcal Protein SufC Binds to Host Plasminogen and Promotes Its Conversion into Plasmin

  • Yoshihito Yasui,
  • Satoru Hirayama,
  • Takumi Hiyoshi,
  • Toshihito Isono,
  • Hisanori Domon,
  • Tomoki Maekawa,
  • Koichi Tabeta and
  • Yutaka Terao

Streptococcus pneumoniae causes otitis media, sinusitis, and serious diseases such as pneumonia and bacteremia. However, the in vivo dynamics of S. pneumoniae infections and disease severity are not fully understood. In this study, we investigated pn...

  • Review
  • Open Access
25 Citations
7,361 Views
30 Pages

Diatom–bacteria interactions evolved during more than 200 million years of coexistence in the same environment. In this time frame, they established complex and heterogeneous cohorts and consortia, creating networks of multiple cell-to-cell mut...

  • Article
  • Open Access
5 Citations
1,991 Views
31 Pages

A-Type Natriuretic Peptide Alters the Impact of Azithromycin on Planktonic Culture and on (Monospecies and Binary) Biofilms of Skin Bacteria Kytococcus schroeteri and Staphylococcus aureus

  • Ekaterina V. Diuvenji,
  • Ekaterina D. Nevolina,
  • Ilya D. Solovyev,
  • Marina V. Sukhacheva,
  • Sergey V. Mart’yanov,
  • Aleksandra S. Novikova,
  • Marina V. Zhurina,
  • Vladimir K. Plakunov and
  • Andrei V. Gannesen

It has been established that the human atrial natriuretic peptide is able to alter the effect of azithromycin on Kytococcus schroeteri H01 and Staphylococcus aureus 209P monospecies and binary biofilms. The effect of the hormone depends on the s...

  • Article
  • Open Access
10 Citations
2,397 Views
20 Pages

Identification of Fungicide Combinations for Overcoming Plasmopara viticola and Botrytis cinerea Fungicide Resistance

  • Junrui Zhang,
  • Jhulia Gelain,
  • Guido Schnabel,
  • Samavath Mallawarachchi,
  • Haoqi Wang,
  • Nirmitee Mulgaonkar,
  • Raghupathy Karthikeyan and
  • Sandun Fernando

Fungal diseases, including downy mildew (caused by Plasmopara viticola) and gray mold (caused by Botrytis cinerea), significantly impact the marketable yield of grapes produced worldwide. Cytochrome b of the mitochondrial respiratory chain of these t...

  • Article
  • Open Access
7 Citations
2,733 Views
13 Pages

Ceftobiprole is a fifth-generation cephalosporin used for different Gram-positive bacterial infections. A population pharmacokinetic analysis was conducted in real-life clinical patients to assess the adequacy of current dosages. Population pharmacok...

  • Review
  • Open Access
5 Citations
4,512 Views
13 Pages

Hantavirus Pulmonary Syndrome Caused by Puumala Orthohantavirus—A Case Report and Literature Review

  • Marija Santini,
  • Jelena Ljubić,
  • Nikola Šoštar,
  • Tatjana Vilibić-Čavlek,
  • Maja Bogdanić,
  • Samo Zakotnik,
  • Tatjana Avšič-Županc,
  • Miša Korva,
  • Ivan Christian Kurolt and
  • Snjezana Židovec-Lepej
  • + 10 authors

In this article, we report on a rare case of acute respiratory distress syndrome (ARDS) caused by the Puumala orthohantavirus (PUUV), which is typically associated with hemorrhagic fever with renal syndrome (HFRS). This is the first documented case o...

  • Article
  • Open Access
4 Citations
2,733 Views
17 Pages

The Restriction–Modification Systems of Clostridium carboxidivorans P7

  • Patrick Kottenhahn,
  • Gabriele Philipps,
  • Boyke Bunk,
  • Cathrin Spröer and
  • Stefan Jennewein

Clostridium carboxidivorans P7 (DSM 15243) is a bacterium that converts syngas (a mixture of CO, H2, and CO2) into hexanol. An optimized and scaled-up industrial process could therefore provide a renewable source of fuels and chemicals while consumin...

  • Article
  • Open Access
1 Citations
2,721 Views
13 Pages

In this study, we reported the complete genome sequence of Shewanella oncorhynchi for the first time. S. oncorhynchi Z-P2 is a bacterium that produces the siderophore putrebactin. Its genome consists of a circular chromosome of 5,034,612 bp with a G...

  • Article
  • Open Access
6 Citations
2,747 Views
14 Pages

The Effect of Fruit and Berry Pomaces on the Growth Dynamics of Microorganisms and Sensory Properties of Marinated Rainbow Trout

  • Mati Roasto,
  • Mihkel Mäesaar,
  • Tõnu Püssa,
  • Dea Anton,
  • Reelika Rätsep,
  • Terje Elias,
  • Salli Jortikka,
  • Merilin Pärna,
  • Karmen Kapp and
  • Kadrin Meremäe
  • + 2 authors

Plant pomaces in suitable forms (powders, extracts) can be used in foods of animal origin to increase the nutritional value and safety of these foods. In the present study, water extracts of apple, black currant, rhubarb and tomato pomaces were used...

  • Article
  • Open Access
4 Citations
2,598 Views
11 Pages

Antimicrobial Activity of Stilbenes from Bletilla striata against Cutibacterium acnes and Its Effect on Cell Membrane

  • Qian Yu,
  • Luyao Sun,
  • Fu Peng,
  • Chen Sun,
  • Fang Xiong,
  • Meiji Sun,
  • Juan Liu,
  • Cheng Peng and
  • Qinmei Zhou

The abnormal proliferation of Cutibacterium acnes is the main cause of acne vulgaris. Natural antibacterial plant extracts have gained great interest due to the efficacy and safety of their use in skin care products. Bletilla striata is a common exte...

  • Review
  • Open Access
45 Citations
5,510 Views
18 Pages

Long COVID or Post-COVID-19 Condition: Past, Present and Future Research Directions

  • César Fernández-de-las-Peñas,
  • Arkiath Veettil Raveendran,
  • Rocco Giordano and
  • Lars Arendt-Nielsen

The presence of symptoms after an acute SARS-CoV-2 infection (long-COVID) has become a worldwide healthcare emergency but remains underestimated and undertreated due to a lack of recognition of the condition and knowledge of the underlying mechanisms...

  • Article
  • Open Access
12 Citations
3,536 Views
16 Pages

Oral Microbial Profile Analysis in Patients with Oral and Pharyngeal Cancer Reveals That Tumoral Fusobacterium nucleatum Promotes Oral Cancer Progression by Activating YAP

  • Yuki Yamamoto,
  • Tomonori Kamiya,
  • Megumu Yano,
  • Vu Thuong Huyen,
  • Masahiro Oishi,
  • Miki Nishio,
  • Akira Suzuki,
  • Kishiko Sunami and
  • Naoko Ohtani

The incidence of oral cancer has recently been increasing worldwide, particularly among young individuals and women. The primary risk factors for head and neck cancers, including oral and pharyngeal cancers, are smoking, alcohol consumption, poor ora...

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Microorganisms - ISSN 2076-2607