Microorganisms, Volume 11, Issue 12
2023 December - 187 articles
Cover Story: Cutaneous leishmaniasis (CL) is the most common clinical presentation of leishmaniasis, a Neglected Tropical Disease (NTD). While other presentations of leishmaniasis can be fatal, CL is mostly non-lethal and despite its prevalence not a priority for drug treatment. Yet, CL can be disfiguring and cause prolonged suffering in afflicted individuals. Several drugs are currently used to treat leishmaniasis, although they often have harsh side effects and long treatment regimens, and drug resistance is emerging across the globe. In search of novel drug therapies, researchers have been using biochemical and computational techniques for early-stage drug discovery efforts. This review focuses on the substantial yet fragmented progress in drug discovery for CL and highlights the common challenges for researchers. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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