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Pathogens, Volume 12, Issue 8

August 2023 - 97 articles

Cover Story: Tick-borne pathogens (TBPs) pose a significant problem globally, particularly in tropical and subtropical regions, impacting both livestock industries and animal health. In Cuba, key pathogens affecting cattle include Babesia bovis, Babesia bigemina, and Anaplasma marginale. These pathogens are primarily transmitted by the Rhipicephalus microplus tick. Diagnosing these infections is challenging, due to low parasitemia levels during persistent infections and cross-reactivity. Molecular techniques such as PCR variants are essential for diagnosis. A drawback of PCR-based methods is their inability to simultaneously detect pathogens. However, high-throughput microfluidic methods enable for the concurrent detection of various pathogens. This study aims to investigate TBPs in cattle and ticks at four sampling points using real-time microfluidic PCR. View this paper
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Articles (97)

  • Article
  • Open Access
22 Citations
19,364 Views
14 Pages

Factors Affecting the Spread, Diagnosis, and Control of African Swine Fever in the Philippines

  • Chia-Hui Hsu,
  • Rachel Schambow,
  • Maximino Montenegro,
  • Ruth Miclat-Sonaco and
  • Andres Perez

21 August 2023

African Swine Fever (ASF) is a highly contagious disease that threatens the swine industry globally. Since its introduction into the Philippines in 2019, ASF has spread extensively in both commercial and backyard farms. Here, using a mix of qualitati...

  • Systematic Review
  • Open Access
13 Citations
4,954 Views
21 Pages

Comparative Analysis of the Prevalence of Bovine Viral Diarrhea Virus in Cattle Populations Based on Detection Methods: A Systematic Review and Meta-Analysis

  • Gebremeskel Mamu Werid,
  • Farhid Hemmatzadeh,
  • Darren Miller,
  • Michael P. Reichel,
  • Yohannes E. Messele and
  • Kiro Petrovski

21 August 2023

Infectious diseases of cattle, including bovine viral diarrhea (BVD), pose a significant health threat to the global livestock industry. This study aimed to investigate the prevalence and risk factors associated with bovine viral diarrhea virus (BVDV...

  • Communication
  • Open Access
3,019 Views
5 Pages

21 August 2023

Because both Babesia microti and Borrelia burgdorferi can be transmitted by the bite of a single coinfected Ixodes scapularis tick, an attempt was made to determine the frequency with which whole blood samples that tested positive for B. microti infe...

  • Article
  • Open Access
5 Citations
3,214 Views
18 Pages

Genomic and Phylogenetic Analysis of Bacillus cereus Biovar anthracis Isolated from Archival Bone Samples Reveals Earlier Natural History of the Pathogen

  • Michael H. Norris,
  • Diansy Zincke,
  • David J. Daegling,
  • John Krigbaum,
  • W. Scott McGraw,
  • Alexander Kirpich,
  • Ted L. Hadfield and
  • Jason K. Blackburn

20 August 2023

(1) Background: Bacillus cereus biovar anthracis (Bcbva) was the causative agent of an anthrax-like fatal disease among wild chimpanzees in 2001 in Côte d’Ivoire. Before this, there had not been any description of an anthrax-like disease...

  • Article
  • Open Access
2,420 Views
12 Pages

19 August 2023

Staphylococcus epidermidis is a major nosocomial pathogen with a remarkable ability to adhere to the surfaces of indwelling medical devices and form biofilms. Unlike other nosocomial pathogens, the interaction of S. epidermidis with host factors has...

  • Article
  • Open Access
1 Citations
1,932 Views
18 Pages

The Therapeutic Potential of Angeli’s Salt in Mitigating Acute Trypanosoma cruzi Infection in Mice

  • Vera Lúcia Hideko Tatakihara,
  • Aparecida Donizette Malvezi,
  • Rito Santo Pereira,
  • Bruno Fernando Cruz Lucchetti,
  • Lucas Felipe Dos Santos,
  • Rubens Cecchini,
  • Lucy Megumi Yamauchi,
  • Sueli Fumie Yamada-Ogatta,
  • Katrina M. Miranda and
  • Waldiceu A. Verri
  • + 2 authors

19 August 2023

Chagas disease (CD), caused by Trypanosoma cruzi, is a neglected tropical disease prevalent in Latin America. Infected patients are treated to eliminate the parasite, reduce the cardiomyopathy risk, and interrupt the disease transmission cycle. The W...

  • Article
  • Open Access
7 Citations
2,244 Views
24 Pages

Genomic Characterization of Listeria innocua Isolates Recovered from Cattle Farms, Beef Abattoirs, and Retail Outlets in Gauteng Province, South Africa

  • James Gana,
  • Nomakorinte Gcebe,
  • Rian Ewald Pierneef,
  • Yi Chen,
  • Rebone Moerane and
  • Abiodun Adewale Adesiyun

18 August 2023

Whole-genome sequencing (WGS) was used for the genomic characterization of one hundred and ten strains of Listeria innocua (L. innocua) isolated from twenty-three cattle farms, eight beef abattoirs, and forty-eight retail outlets in Gauteng prov...

  • Review
  • Open Access
4 Citations
7,550 Views
19 Pages

Malaria Genomics, Vaccine Development, and Microbiome

  • Xinzhuan Su,
  • Rachel V. Stadler,
  • Fangzheng Xu and
  • Jian Wu

18 August 2023

Recent advances in malaria genetics and genomics have transformed many aspects of malaria research in areas of molecular evolution, epidemiology, transmission, host–parasite interaction, drug resistance, pathogenicity, and vaccine development....

  • Article
  • Open Access
5 Citations
2,731 Views
13 Pages

The Program for the Control of Visceral Leishmaniasis in Brazil: The Effect of the Systematic Euthanasia of Seropositive Dogs as a Single Control Action in Porteirinha, a Brazilian City with an Intense Transmission of Visceral Leishmaniasis

  • João Carlos França-Silva,
  • Rodolfo Cordeiro Giunchetti,
  • Reysla Maria da Silveira Mariano,
  • George Luiz Lins Machado-Coelho,
  • Luciana de Almeida Silva Teixeira,
  • Ricardo Andrade Barata,
  • Érika Monteiro Michalsky,
  • Marília Fonseca Rocha,
  • Consuelo Latorre Fortes-Dias and
  • Edelberto Santos Dias

18 August 2023

Background: Porteirinha is endemic for visceral leishmaniasis (VL), with intense disease transmission of the disease. We evaluated the impact of canine euthanasia as a single control measure on the incidence of VL in humans and canines. Methods: A pr...

  • Case Report
  • Open Access
3 Citations
2,878 Views
9 Pages

Bovine Papillomavirus Type 1 Infection in an Equine Congenital Papilloma

  • Raffaella Maggi,
  • Livia De Paolis,
  • Daria De Santis,
  • Valerio Gaetano Vellone,
  • Chiara Grazia De Ciucis,
  • Floriana Fruscione,
  • Katia Mazzocco,
  • Alessandro Ghelardi,
  • Giuseppe Marruchella and
  • Elisabetta Razzuoli

18 August 2023

Papillomas are benign epithelial lesions protruding on the epithelial surfaces as finger-like or warty projections. These lesions are often caused by papillomavirus (PV) infection. Congenital papillomas have been reported in foals. However, to date,...

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Pathogens - ISSN 2076-0817