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Diagnostics, Volume 13, Issue 14

2023 July-2 - 154 articles

Cover Story: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent condition, lacking specific noninvasive diagnostic tools, whose pathogenesis comprises liver mitochondrial dysfunction. Garrafa and colleagues measured mitochondrial bioenergetics in peripheral blood mononuclear cells (PBMCs). They found significantly reduced basal respiration, ATP production, maximal respiration, and spare respiratory capacity in NAFLD compared to non-NAFLD cases. Correlation plots showed intriguing correlations between the respiratory parameters and anthropometric or biochemical parameters of interest for NAFLD diagnosis. Machine learning methods identified ATP production among the best NAFLD predictors. The authors propose blood cell respirometry as a novel tool for NAFLD diagnosis and therapeutic response monitoring. View this paper
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Articles (154)

  • Review
  • Open Access
5 Citations
3,613 Views
17 Pages

Our purpose is to describe blue-light fundus autofluorescence (BAF) features of inflammatory diseases of the outer retina characterised by photoreceptor damage. BAF from patients diagnosed with secondary and primary inflammatory photoreceptor damage...

  • Article
  • Open Access
88 Citations
3,108 Views
14 Pages

A First Computational Frame for Recognizing Heparin-Binding Protein

  • Wen Zhu,
  • Shi-Shi Yuan,
  • Jian Li,
  • Cheng-Bing Huang,
  • Hao Lin and
  • Bo Liao

Heparin-binding protein (HBP) is a cationic antibacterial protein derived from multinuclear neutrophils and an important biomarker of infectious diseases. The correct identification of HBP is of great significance to the study of infectious diseases....

  • Article
  • Open Access
3 Citations
2,163 Views
11 Pages

Triiodothyronine and Protein Malnutrition Could Influence Pulse Wave Velocity in Pre-Dialysis Chronic Kidney Disease Patients

  • Crina Claudia Rusu,
  • Ina Kacso,
  • Diana Moldovan,
  • Alina Potra,
  • Dacian Tirinescu,
  • Maria Ticala,
  • Ancuta M. Rotar,
  • Remus Orasan,
  • Cristian Budurea and
  • Madalina Ticolea
  • + 4 authors

Cardiovascular diseases (CVD) are the first cause of chronic kidney disease (CKD) mortality. For personalized improved medicine, detecting correctable markers of CVD can be considered a priority. The aim of this study was the evaluation of the impact...

  • Systematic Review
  • Open Access
21 Citations
4,005 Views
35 Pages

The Predictive Capabilities of Artificial Intelligence-Based OCT Analysis for Age-Related Macular Degeneration Progression—A Systematic Review

  • George Adrian Muntean,
  • Anca Marginean,
  • Adrian Groza,
  • Ioana Damian,
  • Sara Alexia Roman,
  • Mădălina Claudia Hapca,
  • Maximilian Vlad Muntean and
  • Simona Delia Nicoară

The era of artificial intelligence (AI) has revolutionized our daily lives and AI has become a powerful force that is gradually transforming the field of medicine. Ophthalmology sits at the forefront of this transformation thanks to the effortless ac...

  • Article
  • Open Access
14 Citations
4,220 Views
28 Pages

In the past few years, deep learning has gained increasingly widespread attention and has been applied to diagnosing benign and malignant thyroid nodules. It is difficult to acquire sufficient medical images, resulting in insufficient data, which hin...

  • Article
  • Open Access
4 Citations
3,181 Views
15 Pages

Diagnostic Role of Native T1 Mapping Compared to Conventional Magnetic Resonance Techniques in Cardiac Disease in a Real-Life Cohort

  • Giovanni Donato Aquaro,
  • Silvia Monastero,
  • Giancarlo Todiere,
  • Andrea Barison,
  • Carmelo De Gori,
  • Crysanthos Grigoratos,
  • Maria Luisa Parisella,
  • Lorenzo Faggioni,
  • Dania Cioni and
  • Emanuele Neri
  • + 1 author

We sought to compare native T1 mapping to conventional late gadolinium enhancement (LGE) and T2-STIR techniques in a cohort of consecutive patients undergoing cardiac MRI (CMR). CMR was performed in 323 patients, 206 males (64%), mean age 54 ±...

  • Review
  • Open Access
38 Citations
11,246 Views
24 Pages

Cancer is an incurable disease based on unregulated cell division. Breast cancer is the most prevalent cancer in women worldwide, and early detection can lower death rates. Medical images can be used to find important information for locating and dia...

  • Interesting Images
  • Open Access
2,429 Views
5 Pages

Metastatic urothelial carcinoma of the renal pelvis (MUCP), a type of metastatic upper tract urothelial carcinoma (MUTUC), is a rare malignancy, and some patients with MUCP present with distant metastasis at the time of diagnosis. MUCP in the gastroi...

  • Article
  • Open Access
25 Citations
13,943 Views
19 Pages

White blood cells (WBCs) are crucial components of the immune system that play a vital role in defending the body against infections and diseases. The identification of WBCs subtypes is useful in the detection of various diseases, such as infections,...

  • Review
  • Open Access
5 Citations
3,740 Views
12 Pages

The gold standard for polypoidal choroidal vasculopathy (PCV) diagnosis is indocyanine green angiography (ICGA), but optical coherence tomography angiography (OCTA) has shown promise for PCV imaging in recent years. However, earlier generations of OC...

  • Interesting Images
  • Open Access
2 Citations
2,739 Views
6 Pages

Cat Scratch Disease—A Benign Disease with Thymic Hyperplasia Mimicking Lymphoma

  • Ming Hui Leong,
  • Mohd Jadi Nabillah,
  • Iqbal Hussain Rizuana,
  • Abdullah Asma,
  • Thean Yean Kew and
  • Geok Chin Tan

Cat scratch disease (CSD) is a benign condition caused by the inoculation of Bartonella henselae. The imaging findings are non-specific, and it is difficult to diagnose the disease via imaging. However, imaging studies help exclude other differential...

  • Review
  • Open Access
5 Citations
2,400 Views
10 Pages

Robot-Guided Ultrasonography in Surgical Interventions

  • Răzvan Alexandru Ciocan,
  • Florin Graur,
  • Andra Ciocan,
  • Cosmin Andrei Cismaru,
  • Sebastian Romeo Pintilie,
  • Ioana Berindan-Neagoe,
  • Nadim Al Hajjar and
  • Claudia Diana Gherman

Introduction. The introduction of robotic-guided procedures in surgical techniques has brought an increase in the accuracy and control of resections. Surgery has evolved as a technique since the development of laparoscopy, which has added to the visu...

  • Article
  • Open Access
5 Citations
2,074 Views
21 Pages

Oral cancer is introduced as the uncontrolled cells’ growth that causes destruction and damage to nearby tissues. This occurs when a sore or lump grows in the mouth that does not disappear. Cancers of the cheeks, lips, floor of the mouth, tongu...

  • Article
  • Open Access
11 Citations
2,708 Views
13 Pages

Electric Bioimpedance Sensing for the Detection of Head and Neck Squamous Cell Carcinoma

  • Andrea Luigi Camillo Carobbio,
  • Zhuoqi Cheng,
  • Tomaso Gianiorio,
  • Francesco Missale,
  • Stefano Africano,
  • Alessandro Ascoli,
  • Marco Fragale,
  • Marta Filauro,
  • Filippo Marchi and
  • Leonardo S. Mattos
  • + 5 authors

The early detection of head and neck squamous cell carcinoma (HNSCC) is essential to improve patient prognosis and enable organ and function preservation treatments. The objective of this study is to assess the feasibility of using electrical bioimpe...

  • Review
  • Open Access
8 Citations
4,768 Views
12 Pages

Robotic Colonoscopy and Beyond: Insights into Modern Lower Gastrointestinal Endoscopy

  • Emanuele Tumino,
  • Pierfrancesco Visaggi,
  • Valeria Bolognesi,
  • Linda Ceccarelli,
  • Christian Lambiase,
  • Sergio Coda,
  • Purushothaman Premchand,
  • Massimo Bellini,
  • Nicola de Bortoli and
  • Emanuele Marciano

Lower gastrointestinal endoscopy is considered the gold standard for the diagnosis and removal of colonic polyps. Delays in colonoscopy following a positive fecal immunochemical test increase the likelihood of advanced adenomas and colorectal cancer...

  • Article
  • Open Access
9 Citations
3,366 Views
13 Pages

Artificial Intelligence-Assisted Processing of Anterior Segment OCT Images in the Diagnosis of Vitreoretinal Lymphoma

  • Fabrizio Gozzi,
  • Marco Bertolini,
  • Pietro Gentile,
  • Laura Verzellesi,
  • Valeria Trojani,
  • Luca De Simone,
  • Elena Bolletta,
  • Valentina Mastrofilippo,
  • Enrico Farnetti and
  • Luca Cimino
  • + 12 authors

Anterior segment optical coherence tomography (AS-OCT) allows the explore not only the anterior chamber but also the front part of the vitreous cavity. Our cross-sectional single-centre study investigated whether AS-OCT can distinguish between vitreo...

  • Article
  • Open Access
5 Citations
4,678 Views
14 Pages

The purpose of this study was to evaluate the efficiency of two therapeutic procedures clinically and microbiologically in the management of periodontally affected teeth: scaling and root planing alone and the laser-assisted new attachment procedure...

  • Review
  • Open Access
5 Citations
2,864 Views
13 Pages

Biofluid Biomarkers in the Prognosis of Chronic Subdural Hematoma: A Systematic Scoping Review

  • Georgios Georgountzos,
  • Ioannis Gkalonakis,
  • Lykourgos Anastasopoulos,
  • George Stranjalis and
  • Theodosis Κalamatianos

The present systematic scoping review aimed at mapping and analyzing the available literature on biological fluid (biofluid) biomarkers showing promise in the prediction of chronic subdural hematoma (cSDH) recurrence and the prognosis of neurological...

  • Article
  • Open Access
11 Citations
2,668 Views
10 Pages

Heterogeneity of Glycolytic Phenotype Determined by 18F-FDG PET/CT Using Coefficient of Variation in Patients with Advanced Non-Small Cell Lung Cancer

  • Sara Pellegrino,
  • Rosa Fonti,
  • Armin Hakkak Moghadam Torbati,
  • Roberto Bologna,
  • Rocco Morra,
  • Vincenzo Damiano,
  • Elide Matano,
  • Sabino De Placido and
  • Silvana Del Vecchio

We investigated the role of Coefficient of Variation (CoV), a first-order texture parameter derived from 18F-FDG PET/CT, in the prognosis of Non-Small Cell Lung Cancer (NSCLC) patients. Eighty-four patients with advanced NSCLC who underwent 18F-FDG P...

  • Article
  • Open Access
6 Citations
3,145 Views
13 Pages

Reagent Effects on the Activated Partial Thromboplastin Time Clot Waveform Analysis: A Multi-Centre Study

  • Wan Hui Wong,
  • Chuen Wen Tan,
  • Nabeelah Binti Abdul Khalid,
  • Nadjwa Zamalek Dalimoenthe,
  • Christina Yip,
  • Chaicharoen Tantanate,
  • Rodelio D. Lim,
  • Ji Hyun Kim and
  • Heng Joo Ng

(1) Background: The activated partial thromboplastin time (APTT)- based clot waveform analysis (CWA) quantitatively extends information obtained from the APTT waveform through its derivatives. However, pre-analytical variables including reagent effec...

  • Article
  • Open Access
8 Citations
3,518 Views
21 Pages

The Impact of the COVID-19 Pandemic on Outcomes in Acute Pancreatitis: A Propensity Score Matched Study Comparing before and during the Pandemic

  • Patricia Mihaela Rădulescu,
  • Elena Irina Căluianu,
  • Emil Tiberius Traşcă,
  • Dorin Mercuţ,
  • Ion Georgescu,
  • Eugen Florin Georgescu,
  • Eleonora Daniela Ciupeanu-Călugăru,
  • Maria Filoftea Mercuţ,
  • Răzvan Mercuţ and
  • Dumitru Rădulescu
  • + 3 authors

We aimed to evaluate the outcomes and survival of patients with acute pancreatitis who shared the same clinical form, age, and sex before the pandemic, during the pandemic, and among those with confirmed COVID-19 infection upon hospital admission. Th...

  • Article
  • Open Access
9 Citations
5,642 Views
11 Pages

Exploring Extended White Blood Cell Parameters for the Evaluation of Sepsis among Patients Admitted to Intensive Care Units

  • Sook Fong Ho,
  • Swee Jin Tan,
  • Mohd Zulfakar Mazlan,
  • Salfarina Iberahim,
  • Ying Xian Lee and
  • Rosline Hassan

Sepsis is a major cause of mortality and morbidity in intensive care units. This case–control study aimed to investigate the haematology cell population data and extended inflammatory parameters for sepsis management. The study included three g...

  • Review
  • Open Access
4 Citations
4,383 Views
21 Pages

Early Optical Coherence Tomography Biomarkers for Selected Retinal Diseases—A Review

  • Ewa Goździewska,
  • Małgorzata Wichrowska and
  • Jarosław Kocięcki

Optical coherence tomography (OCT) is a non-invasive, easily accessible imaging technique that enables diagnosing several retinal diseases at various stages of development. This review discusses early OCT findings as non-invasive imaging biomarkers f...

  • Article
  • Open Access
39 Citations
10,052 Views
25 Pages

Atrial fibrillation is a prevalent cardiac arrhythmia that poses significant health risks to patients. The use of non-invasive methods for AF detection, such as Electrocardiogram and Photoplethysmogram, has gained attention due to their accessibility...

  • Article
  • Open Access
10 Citations
2,565 Views
17 Pages

From Euglycemia to Recent Onset of Type 2 Diabetes Mellitus: A Proof-of-Concept Study on Circulating microRNA Profiling Reveals Distinct, and Early microRNA Signatures

  • Marta Greco,
  • Maria Mirabelli,
  • Alessandro Salatino,
  • Francesca Accattato,
  • Vincenzo Aiello,
  • Francesco S. Brunetti,
  • Eusebio Chiefari,
  • Salvatore A. Pullano,
  • Antonino S. Fiorillo and
  • Antonio Brunetti
  • + 1 author

Background and aim—Alterations in circulating microRNA (miRNA) expression patterns are thought to be involved in the early stages of prediabetes, as well as in the progression to overt type 2 diabetes mellitus (T2D) and its vascular complicatio...

  • Review
  • Open Access
10 Citations
11,506 Views
15 Pages

Background: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes mellitus and can lead to patient demise if not immediately treated. From the recent literature, the diabetic ketoacidosis mortality rate, depending on age, i...

  • Review
  • Open Access
8 Citations
5,404 Views
29 Pages

Thoracic Diseases: Technique and Applications of Dual-Energy CT

  • Armando Perrella,
  • Giulio Bagnacci,
  • Nunzia Di Meglio,
  • Vito Di Martino and
  • Maria Antonietta Mazzei

Dual-energy computed tomography (DECT) is one of the most promising technological innovations made in the field of imaging in recent years. Thanks to its ability to provide quantitative and reproducible data, and to improve radiologists’ confid...

  • Review
  • Open Access
15 Citations
4,378 Views
24 Pages

Medical Radiology: Current Progress

  • Alessia Pepe,
  • Filippo Crimì,
  • Federica Vernuccio,
  • Giulio Cabrelle,
  • Amalia Lupi,
  • Chiara Zanon,
  • Sebastiano Gambato,
  • Anna Perazzolo and
  • Emilio Quaia

Recently, medical radiology has undergone significant improvements in patient management due to advancements in image acquisition by the last generation of machines, data processing, and the integration of artificial intelligence. In this way, cardio...

  • Article
  • Open Access
11 Citations
2,608 Views
14 Pages

Objectives: To assess diagnostic performance of standard radial k-space (PROPELLER) MRI sequences and compare with accelerated acquisitions combined with a deep learning-based convolutional neural network (DL-CNN) reconstruction for evaluation of the...

  • Review
  • Open Access
16 Citations
2,926 Views
16 Pages

Pediatric COVID-19 and Diabetes: An Investigation into the Intersection of Two Pandemics

  • Silvia Fotea,
  • Cristina Mihaela Ghiciuc,
  • Gabriela Stefanescu,
  • Anca Lavinia Cianga,
  • Cristina Maria Mihai,
  • Ancuta Lupu,
  • Lacramioara Ionela Butnariu,
  • Iuliana Magdalena Starcea,
  • Delia Lidia Salaru and
  • Vasile Valeriu Lupu
  • + 4 authors

Coronavirus disease 2019 (COVID-19) is a complex infectious disease caused by the SARS-CoV-2 virus, and it currently represents a worldwide public health emergency. The pediatric population is less prone to develop severe COVID-19 infection, but chil...

  • Review
  • Open Access
17 Citations
4,670 Views
17 Pages

The Evolving Concept of the Multidisciplinary Approach in the Diagnosis and Management of Interstitial Lung Diseases

  • Stefano Sanduzzi Zamparelli,
  • Alessandro Sanduzzi Zamparelli and
  • Marialuisa Bocchino

Background: Interstitial lung diseases (ILDs) are a group of heterogeneous diseases characterized by inflammation and/or fibrosis of the lung interstitium, leading to a wide range of clinical manifestations and outcomes. Over the years, the literatur...

  • Article
  • Open Access
7 Citations
1,979 Views
15 Pages

Contrast-Enhanced Computed Tomography and Laboratory Parameters as Non-Invasive Diagnostic Markers of Pancreatic Fibrosis

  • Igor E. Khatkov,
  • Dmitry S. Bordin,
  • Konstantin A. Lesko,
  • Elena A. Dubtsova,
  • Nikolay S. Karnaukhov,
  • Maria A. Kiriukova,
  • Nadezhda V. Makarenko,
  • Alexey S. Dorofeev,
  • Irina V. Savina and
  • Ludmila V. Vinokurova
  • + 2 authors

Pancreatic fibrosis (PF) is a part of the pathogenesis in most pancreatic disorders and plays a crucial role in chronic pancreatitis development. The aim of our study was to investigate a relationship between PF grade and signs in resected pancreatic...

  • Article
  • Open Access
3 Citations
3,788 Views
12 Pages

Power Drill Craniostomy for Bedside Intracranial Access in Traumatic Brain Injury Patients

  • Hansen Deng,
  • David J. Puccio,
  • Sharath K. Anand,
  • John K. Yue,
  • Joseph S. Hudson,
  • Andrew D. Legarreta,
  • Zhishuo Wei,
  • David O. Okonkwo,
  • Ava M. Puccio and
  • Enyinna L. Nwachuku

Invasive neuromonitoring is a bedrock procedure in neurosurgery and neurocritical care. Intracranial hypertension is a recognized emergency that can potentially lead to herniation, ischemia, and neurological decline. Over 50,000 external ventricular...

  • Article
  • Open Access
15 Citations
17,546 Views
14 Pages

Clinical Impact of the BIOFIRE Blood Culture Identification 2 Panel in Adult Patients with Bloodstream Infection: A Multicentre Observational Study in the United Arab Emirates

  • Abiola Senok,
  • Laila Al Dabal,
  • Mubarak Alfaresi,
  • Maya Habous,
  • Handan Celiloglu,
  • Safia Bashiri,
  • Naama Almaazmi,
  • Hassan Ahmed,
  • Ayman A. Mohmed and
  • Basel Salama
  • + 5 authors

Rapid pathogen identification is key to the proper management of patients with bloodstream infections (BSIs), especially in the intensive care setting. This multicentre study compared the time to pathogen identification results in 185 patients admitt...

  • Article
  • Open Access
11 Citations
3,413 Views
11 Pages

(1) Background: Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional (3D) spine deformity. The Cobb angle, evaluated with 2D radiography, is the gold standard to determine curve severity. The primary aim of this study was to evaluate the 3D s...

  • Article
  • Open Access
1 Citations
2,570 Views
17 Pages

Predictive Value of [99mTc]-MAA-Based Dosimetry in Hepatocellular Carcinoma Patients Treated with [90Y]-TARE: A Single-Center Experience

  • Michael Doppler,
  • Marlene Reincke,
  • Dominik Bettinger,
  • Katharina Vogt,
  • Jakob Weiss,
  • Michael Schultheiss,
  • Wibke Uller,
  • Niklas Verloh and
  • Christian Goetz

Transarterial radioembolization is a well-established method for the treatment of hepatocellular carcinoma. The tolerability and incidence of hepatic decompensation are related to the doses delivered to the tumor and healthy liver. This retrospective...

  • Review
  • Open Access
64 Citations
16,366 Views
33 Pages

Artificial Intelligence in Neurosurgery: A State-of-the-Art Review from Past to Future

  • Jonathan A. Tangsrivimol,
  • Ethan Schonfeld,
  • Michael Zhang,
  • Anand Veeravagu,
  • Timothy R. Smith,
  • Roger Härtl,
  • Michael T. Lawton,
  • Adham H. El-Sherbini,
  • Daniel M. Prevedello and
  • Chayakrit Krittanawong
  • + 1 author

In recent years, there has been a significant surge in discussions surrounding artificial intelligence (AI), along with a corresponding increase in its practical applications in various facets of everyday life, including the medical industry. Notably...

  • Article
  • Open Access
6 Citations
4,003 Views
17 Pages

Second-Line Treatment of Metastatic Renal Cell Carcinoma in the Era of Predictive Biomarkers

  • Andreea Ioana Parosanu,
  • Catalin Baston,
  • Ioana Miruna Stanciu,
  • Cristina Florina Parlog and
  • Cornelia Nitipir

Background: Over the past few years, significant advancements have been achieved in the front-line treatment of metastatic renal cell carcinomas (mRCCs). However, most patients will eventually encounter disease progression during this front-line trea...

  • Case Report
  • Open Access
1 Citations
4,188 Views
8 Pages

Liposarcoma of the breast is a rare form of cancerous tumor that can be mistaken for primary breast cancer. A recent instance involved a woman who was 54 years old and went in for her annual screening mammogram. The mammogram revealed that she had a...

  • Review
  • Open Access
23 Citations
6,735 Views
13 Pages

Recent Advances in Colorimetric Tests for the Detection of Infectious Diseases and Antimicrobial Resistance

  • Cagla Celik,
  • Gamze Kalin,
  • Zekeriya Cetinkaya,
  • Nilay Ildiz and
  • Ismail Ocsoy

Diagnosis of infection-causing microorganisms with sensitive, rapid, selective and economical diagnostic tests is critical to start the right treatment. With these tests, the spread of infections can be prevented. In addition to that, the detection o...

  • Systematic Review
  • Open Access
14 Citations
6,015 Views
13 Pages

Copper Deficiency as Wilson’s Disease Overtreatment: A Systematic Review

  • Tomasz Litwin,
  • Agnieszka Antos,
  • Jan Bembenek,
  • Adam Przybyłkowski,
  • Iwona Kurkowska-Jastrzębska,
  • Marta Skowrońska and
  • Anna Członkowska

Background: Treatment of Wilson’s disease (WD), an inherited disease characterized by copper overload, is lifelong and there is the possibility that copper deficiency (CD) may occur. We systematically reviewed the literature to describe treatment pat...

  • Review
  • Open Access
27 Citations
6,706 Views
15 Pages

The Pathophysiology of Collateral Circulation in Acute Ischemic Stroke

  • Marilena Mangiardi,
  • Adriano Bonura,
  • Gianmarco Iaccarino,
  • Michele Alessiani,
  • Maria Cristina Bravi,
  • Domenica Crupi,
  • Francesca Romana Pezzella,
  • Sebastiano Fabiano,
  • Enrico Pampana and
  • Sabrina Anticoli
  • + 2 authors

Cerebral collateral circulation is a network of blood vessels which stabilizes blood flow and maintains cerebral perfusion whenever the main arteries fail to provide an adequate blood supply, as happens in ischemic stroke. These arterial networks are...

  • Article
  • Open Access
12 Citations
2,160 Views
14 Pages

Machine-Learning-Based Diagnostics of Cardiac Sarcoidosis Using Multi-Chamber Wall Motion Analyses

  • Jan Eckstein,
  • Negin Moghadasi,
  • Hermann Körperich,
  • Rehsan Akkuzu,
  • Vanessa Sciacca,
  • Christian Sohns,
  • Philipp Sommer,
  • Julian Berg,
  • Jerzy Paluszkiewicz and
  • Misagh Piran
  • + 1 author

Background: Hindered by its unspecific clinical and phenotypical presentation, cardiac sarcoidosis (CS) remains a challenging diagnosis. Objective: Utilizing cardiac magnetic resonance imaging (CMR), we acquired multi-chamber volumetrics and strain f...

  • Article
  • Open Access
3 Citations
2,300 Views
9 Pages

Aging is associated with muscle atrophy and fatty infiltration of skeletal muscle. The multifidus muscle stabilizes the lumbar spine and undergoes adipose accumulation with age, leading to functional decline in the elderly. Therefore, quantitative as...

  • Article
  • Open Access
4 Citations
3,184 Views
12 Pages

Since class II malocclusion and lack of space within the dental arch due to early loss of deciduous molars is a common orthodontic problem in the Polish population, bone-anchored distalizers are becoming more and more popular. The aim of the present...

  • Article
  • Open Access
3 Citations
2,298 Views
10 Pages

Intracranial Hemorrhage in Hospitalized Patients Following Percutaneous Coronary Intervention: A Large Cohort Analysis from a Single Center

  • Cheng Yang,
  • Yong-Gang Sui,
  • Bin-Cheng Wang,
  • Yan-Lu Xu,
  • Na-Qiong Wu,
  • Yong-Jian Wu,
  • Jian-Jun Li and
  • Jie Qian

Background: There are several reports on the prevalence and characteristics of intracranial hemorrhage (ICH) following percutaneous coronary intervention (PCI), which is a rare but severe complication with high mortality. However, the clinical landsc...

  • Article
  • Open Access
2 Citations
2,993 Views
16 Pages

Influence of [18F]FDG-PET/CT on Clinical Management Decisions in Breast Cancer Patients—A PET/CT Registry Study

  • Sebastian Werner,
  • Julia Sekler,
  • Brigitte Gückel,
  • Christian la Fougère,
  • Konstantin Nikolaou,
  • Christina Pfannenberg,
  • Heike Preibsch,
  • Tobias Engler and
  • Susann-Cathrin Olthof

There is a lack of evidence regarding the clinical impact of [18F]fluorodeoxyglucose positron emission tomography/computed tomography ([18F]FDG-PET/CT, hereinafter referred to as PET/CT), especially regarding management changes and their link to over...

  • Article
  • Open Access
3 Citations
1,848 Views
15 Pages

Bronchial Microbiota and the Stress Associated with Invasive Diagnostic Tests in Lung Cancer vs. Benign Pulmonary Diseases: A Cross-Sectional Study

  • Patricia Hogea,
  • Emanuela Tudorache,
  • Ovidiu Fira-Mladinescu,
  • Camelia Pescaru,
  • Diana Manolescu,
  • Felix Bratosin,
  • Ovidiu Rosca,
  • Manaswini Kakarla,
  • Florin George Horhat and
  • Cristian Oancea

Lung cancer is the leading cause of cancer-related deaths worldwide. This study aimed to compare the bronchial microbiota of patients with lung cancer and patients with benign pulmonary diseases undergoing bronchoscopy, and to assess the stress level...

  • Review
  • Open Access
15 Citations
4,531 Views
24 Pages

The sudden outbreak of the COVID-19 pandemic led to a huge concern globally because of the astounding increase in mortality rates worldwide. The medical imaging computed tomography technique, whole-genome sequencing, and electron microscopy are the m...

  • Article
  • Open Access
12 Citations
4,106 Views
28 Pages

Diagnosis of Obstructive Sleep Apnea Using Feature Selection, Classification Methods, and Data Grouping Based Age, Sex, and Race

  • Alaa Sheta,
  • Thaer Thaher,
  • Salim R. Surani,
  • Hamza Turabieh,
  • Malik Braik,
  • Jingwei Too,
  • Noor Abu-El-Rub,
  • Majdi Mafarjah,
  • Hamouda Chantar and
  • Shyam Subramanian

Obstructive sleep apnea (OSA) is a prevalent sleep disorder that affects approximately 3–7% of males and 2–5% of females. In the United States alone, 50–70 million adults suffer from various sleep disorders. OSA is characterized by...

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Diagnostics - ISSN 2075-4418