2025 September-2 - 118 articles
Background: The growing demand for sustainable and nutrient-rich food has drawn attention to aquatic plants, particularly those of the Lemnoideae subfamily, commonly known as duckweed. These fast-growing plants are rich in high-quality protein and of...
Background and Objective: Humanized models of Alzheimer’s disease (AD) provide valuable tools for investigating the mechanisms of this neurodegenerative disorder, the leading cause of dementia. These models enable the study of AD progression an...
Background: Abnormal mitochondrial energy metabolism is a key factor in the development and progression of cardiac hypertrophy. Hopeaphenol (HP), a tetramer of the natural polyphenol resveratrol, exhibits higher biological activity than resveratrol,...
Background: Childhood obesity is a pro-inflammatory state associated with poorer outcomes in chronic allergic diseases, such as asthma, and in adults, it is a recognized risk factor for more severe anaphylaxis. However, whether this association exten...
Background: Phenylketonuria (PKU) is an inherited metabolic disorder that requires early diagnosis and strict phenylalanine (Phe)-restricted diet to prevent neurocognitive impairment. Various infant feeding models have been used to achieve optimal me...
Background: Among patients who have experienced a myocardial infarction, adherence to the principles of healthy eating becomes particularly important. These behaviors may potentially depend on the level of education. Objectives: The aim of this study...
Background: Malnutrition is highly prevalent in hospitalized older adults and is associated with adverse clinical outcomes. However, the extent to which nutritional care is systematically implemented and its relationship with outcomes remains unclear...
Background: Cardiovascular diseases (CVDs) represent a major global health burden, and cholesterol reduction is a key strategy for their prevention and management. This study investigated the mechanism by which bile salt hydrolase (BSH) from Lactobac...
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) has become one of the most prevalent liver diseases, affecting up to 40% of adults and strongly associated with obesity and metabolic dysfunction. Despite the lack of approv...
Objectives: To examine the association between social media (SM) use and content exposure with the risk of developing eating disorders (EDs) among adolescents. Methods: A descriptive observational study was conducted using a structured questionnaire...
Background: Bone mineralization can be influenced by physical activity and dietary factors; however, the relative contributions of these factors are not well defined. Physical activity in adolescents can be implemented with physical education (PE) cl...
Background: The worldwide prevalence of obesity in children and adolescents quadrupled in the past decades, becoming a public health priority. Following the recommendation by the Italian Minister of Health, the Emilia-Romagna Region started a communi...
Background/Objectives: Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation and inflammation, predominantly affecting women. While recent evidence suggests a systemic pro-inflammatory state in lipedema, the...
Background: Body composition plays a crucial role in metabolic health, aging, and the development of various diseases. Vitamin D has been implicated in the regulation of muscle and adipose tissue function, but its relationship with body composition r...
Background/Objectives: The consumption of ultra-processed foods (UPF) has increased worldwide and has been hypothesized to contribute to chronic diseases, including conditions characterized by inflammatory dysregulation. We conducted a scoping review...
Background: Time-restricted eating (TRE), a dietary strategy that confines daily food intake to specific time windows, has been shown in animal models to enhance physical performance even without exercise training. However, evidence in humans under n...
Background: The primary treatment for inborn errors of metabolism (IEM) involves restricted intake of natural protein. Inadequate diets can lead to an increased risk of inflammation and susceptibility to infections. The Dietary Inflammatory Index (DI...
Background: Food allergies (FAs) have become a major public health concern worldwide, with rising prevalence particularly among children. Traditional genetic and allergen exposure models do not fully explain this increase, prompting growing interest...
Background/Objectives: Sarcopenia is a major public health concern, and early preventive strategies in midlife are increasingly emphasized. The goal of this study was to evaluate the effectiveness of a 12-week lifestyle intervention that included nut...
Background: Manganese (Mn) is a trace element essential for multiple physiological and biological processes. The testis plays a key role in male reproduction by producing sperm and synthesizing male hormones. This study investigates how Mn deficiency...
Background: Metabolic stress from amino acid (AA) insufficiency is increasingly linked to pathological angiogenesis, but specific essential AA (EAA) roles remain undefined. Neovascular age-related macular degeneration (AMD), a major cause of blindnes...
Background/Objectives: Breakfast skipping has been associated with a wide range of adverse health outcomes, including metabolic disorders, disrupted circadian rhythm, and impairments of memory and attention in adolescents and adults. Although partial...
Public health—understood as both a science and a practice aimed at preventing disease, prolonging life, and promoting health—has become one of the most critical domains of institutional action, shaped by both nation-states and internation...
Background/Objectives: Gut microbiota is profoundly influenced by dysglycemic states, including prediabetes (preDM) and type 2 diabetes (T2D). Although short-chain fatty acids (SCFAs) may serve as proxies reflecting these microbial changes, their pre...
Background/Objectives: As global aging accelerates, prevalence of mild cognitive impairment (MCI) continues to rise, challenging healthcare systems and diminishing older adults’ quality of life. There is great interest in better understanding t...
Background/Objectives: Ulcerative colitis (UC) pathogenesis involves gut barrier dysfunction, dysregulated immune responses, and gut microbiota imbalance. Alfalfa polysaccharide (APS), a bioactive compound with immunomodulatory potential, remains und...
Background: Apple cider vinegar (ACV) is a naturally fermented beverage with potential metabolic health benefits; however, its effects on weight loss remain controversial. This systematic review and meta-analysis of randomized controlled trials (RCTs...
Background/Objectives: Dental plaque, a biofilm composed of accumulated oral microorganisms, is a key contributor to various oral diseases. 6-shogaol, a bioactive compound of ginger, is known to have pharmacological activities, including anticancer,...
Background/Objectives: Treatment for superior mesenteric artery (SMA) syndrome can include either weight restoration (conservative management) or surgical intervention, with the latter recommended when individuals fail conservative management. Howeve...
Low dietary diversity is a key driver of undernutrition and remains a significant public health challenge in low- and middle-income countries. This study evaluated the effect of nutritional counselling and the provision of livestock feed, aimed at su...
Background: Lophatheri Herba, a traditional East Asian herb with documented food uses, contains bioactive flavonoids. This study investigated how Aspergillus oryzae fermentation modifies its short-chain fatty acids (SCFAs) and metabolome, and evaluat...
Background: On 1 October 2019, the Taiwan National Health Insurance (NHI) Administration introduced reimbursement for nutritional care services provided to intensive care unit (ICU) patients, under the category of nutritional care fees. These service...
Background/Objectives: Antenatal multiple micronutrient supplementation (MMS) improves birth outcomes more effectively than iron and folic acid (IFA) supplementation alone. However, the acceptability of MMS among pregnant individuals, a critical fact...
Background and objectives: The objective of this study was to test the effects of objectively measured screen time using wearable cameras, along with dietary intake and physical activity level (and their interaction), on obesity among Chinese school-...
Background/Objectives: Colorectal cancer (CRC) remains a major global health challenge and current therapies are not always effective. In addition, certain immune cell populations, such as myeloid-derived suppressor cells (MDSCs), pose a significant...
Background/Objectives: Breastfeeding is essential to maternal and child health, and multiple factors influence its success. This study examined the factors associated with breastfeeding type among infants aged 0 to 12 weeks. Methods: A mixed-methods...
Background and Aims: Numerous clinical and observational studies have examined the role of vitamin D in glycemic control and metabolic regulation among diabetic patients, but findings remain inconsistent. This meta-analysis aimed to assess the effect...
Background: While the importance of folic acid supplementation during pregnancy in the prevention of neural tube defects in offspring is well established, its potential role in pediatric asthma development remains unclear, with limited evidence to da...
Background: Curcumin (Cur) and tryptophan (Trp) both show promise for treating ulcerative colitis (UC) alone, but their combination has not been explored. This study investigated the therapeutic advantage of the combination (Cur–Trp) for DSS-in...
Background: The inability to assign a protein content claim (PCC) to plant foods may impede efforts from Canada’s Food Guide to increase consumption of plant protein. A systematic application of PCC frameworks from other regions to Canadian nut...
Background/Objectives: The triglyceride–glucose (TyG) index is a surrogate marker of insulin resistance associated with chronic kidney disease (CKD). The effect of TyG index changes on the development of CKD in young adults remains unclear. Met...
Background/Objectives: Autism Spectrum Disorder (ASD) is a neurodevelopmental condition often accompanied by gastrointestinal (GI) symptoms and gut microbiota imbalances. The microbiota–gut–brain (MGB) axis is a bidirectional communicatio...
Background: Physical activity induces the production of reactive oxygen species (ROS), which, at moderate levels mediate beneficial physiological adaptations, including insulin sensitivity and enhanced antioxidant defense. However, excessive ROS prod...
Background: Arginine (Arg) is thought to potentially stimulate protein synthesis. Although the detailed mechanism by which Arg regulates protein synthesis is not fully known, it is believed to occur primarily through the mechanistic target of rapamyc...
Background/Objectives: Diabetic retinopathy is a leading cause of blindness in diabetic patients, with disease susceptibility influenced by both genetic and environmental factors. This study aimed to identify novel genetic variants associated with DR...
Objectives: Multidimensional dietary patterns provide a more comprehensive assessment of meal-related behavior than single behaviors, yet evidence on their variation across adulthood and association with health factors relevant to healthy aging is li...
Background: New tools for monitoring diets, such as the Diet Quality Questionnaire (DQQ), may help reduce the costs and burden associated with traditional methods of diet assessment. However, its proposed sentinel foods require validation in target p...
Background/Objectives: Maternal vitamin supplementation (including folic acid, vitamin D, and multivitamin supplements) during pregnancy may lower the likelihood of neurodevelopmental disorders in offspring. This study examines the associations betwe...
Flavio Bachini was not included as an author in the original publication [...]
Background/Objectives: The association between vitamin C intake and frailty among older adults remains unclear, and evidence from Asian populations is limited. Using nationally representative data, we aimed to examine whether vitamin C supplementatio...
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