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Nutrients, Volume 17, Issue 13

July-1 2025 - 202 articles

Cover Story: Cancer cells often activate the hypoxia pathway and shift their metabolism toward glycolysis. Purple potato extract, a polyphenol-rich natural product, suppresses hypoxia-induced glycolysis while promoting oxidative metabolism. This metabolic reprogramming reduces proliferation, migration, and drug resistance in human colonic epithelial Caco-2 cells. The findings of the present study highlight purple potato extract and related products as promising dietary strategies for colorectal cancer prevention and therapy. View this paper
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Articles (202)

  • Article
  • Open Access
2 Citations
2,468 Views
15 Pages

Ultra-Processed Foods Consumption and Metabolic Syndrome in European Children, Adolescents, and Adults: Results from the I.Family Study

  • Annarita Formisano,
  • Marika Dello Russo,
  • Lauren Lissner,
  • Paola Russo,
  • Wolfgang Ahrens,
  • Stefaan De Henauw,
  • Antje Hebestreit,
  • Timm Intemann,
  • Monica Hunsberger and
  • Dénes Molnár
  • + 9 authors

7 July 2025

Background/Objectives: Ultra-processed foods (UPFs) constitute a large proportion of the daily energy intake of Europeans, particularly among children and adolescents. High UPFs consumption is associated with poor dietary quality and adverse health o...

  • Article
  • Open Access
1 Citations
958 Views
13 Pages

Modulation of Gut Microbial Composition by Lactobacillus delbrueckii subsp. lactis CKDB001 Supplementation in a High-Fat-Diet-Induced Obese Mice

  • Jaeryang Chu,
  • Chae-Won No,
  • Hyunchae Joung,
  • Kyung Hwan Kim,
  • Chang Hun Shin,
  • Jisu Lee and
  • Jung-Heun Ha

7 July 2025

Background/Objectives: Lactobacillus delbrueckii subsp. lactis CKDB001 (LL) has demonstrated anti-inflammatory, antioxidant, and lipid-regulatory effects in vitro and in vivo, including attenuation of hepatic steatosis and modulation of lipid me...

  • Article
  • Open Access
1 Citations
2,537 Views
21 Pages

7 July 2025

Background/Objectives: Probiotics are increasingly recognized for their role in managing gastrointestinal disorders through modulation of gut microbiota. Restoring microbial balance remains a therapeutic challenge. Recent strategies combine probiotic...

  • Systematic Review
  • Open Access
2 Citations
4,337 Views
19 Pages

7 July 2025

Background: Gastrointestinal (GI) symptoms, often reported by individuals with autism spectrum disorders (ASD), may impair functionality and exacerbate behavioral symptoms. Gut dysbiosis has been identified as a potential environmental factor influen...

  • Article
  • Open Access
1,710 Views
27 Pages

7 July 2025

Background/Objectives: The establishment of early gut microbiota is crucial for host health. Lactoferrin (LF), which is present in breast milk, positively impacts gut microbiota composition. However, the effect of lactation LF on the establishment an...

  • Systematic Review
  • Open Access
14,348 Views
25 Pages

7 July 2025

Background/Objectives: Acute respiratory tract infections (ARTIs) are a significant global health burden, contributing to increased healthcare use, absenteeism, and economic strain. While clinical treatments exist, many individuals use traditional di...

  • Article
  • Open Access
2,636 Views
14 Pages

Effects of Prebiotics Inulin and Oat β-Glucan on Colonic Architecture and Hepatic Proteome in Mice with Circadian-Disruption-Aggravated Metabolic Dysfunction-Associated Steatohepatitis

  • Nelson Kei,
  • Kam Kuen Cheung,
  • Ka Lee Ma,
  • Tsz Kwan Yau,
  • Susana Lauw,
  • Xing Kang,
  • Kiwi Wai Yan Sun,
  • Yu Wang,
  • Vincent Wai Sun Wong and
  • Sunny Hei Wong
  • + 1 author

7 July 2025

Background: Circadian disruption (CD) aggravates metabolic dysfunction-associated steatohepatitis (MASH), but supplementation with prebiotics inulin and oat β-glucan may mitigate its effects. However, their impact on colonic architecture and hep...

  • Article
  • Open Access
1 Citations
750 Views
12 Pages

Least Significant Change (LSC) for Serum Concentrations of 25-Hydroxyvitamin D

  • Pawel Pludowski,
  • Marek Wójcik,
  • Maciej Jaworski,
  • Agnieszka Ochocińska,
  • William B. Grant and
  • Michael F. Holick

7 July 2025

Background: The least significant change (LSC) method should be introduced and considered a proper method to define the smallest clinically important difference between two consecutive measurements. Methods: The LSC was calculated based on 150 patien...

  • Article
  • Open Access
2 Citations
1,174 Views
15 Pages

7 July 2025

Background/Objective: Dyslipidemia significantly contributes to cardiovascular disease (CVD), with triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) as key components. While genetics play a key role in lipid levels, the interplay be...

  • Article
  • Open Access
2 Citations
1,835 Views
13 Pages

Diet Diversity and Adherence to a Mediterranean Diet Pattern in Pregnancy Is Protective Against the Development of Early-Childhood Atopic Dermatitis

  • Kristina Nadine Heye,
  • Leonie Helen Bogl,
  • Mari Sasaki,
  • Remo Frei,
  • Anna Breunig,
  • Neeta Bühler,
  • Christian Raphael Kahlert,
  • Mehmet Goekkaya,
  • Claudia Traidl-Hoffmann and
  • Roger Lauener
  • + 2 authors

7 July 2025

Background/Objectives: The role of maternal diet in atopic dermatitis (AD) requires better understanding, as AD often manifests early in life and precedes other allergic diseases. We evaluated the association between maternal diet and AD up to 2 year...

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Nutrients - ISSN 2072-6643