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Nutrients, Volume 11, Issue 10

October 2019 - 290 articles

Cover Story: Gluten-related disorders include celiac disease, wheat allergy and non-celiac wheat sensitivity, which have in common the dietary exposure to gluten and other wheat derivatives as an etiologic factor. Of notice, each present a unique pathophysiology: celiac disease is mainly a T-cell mediated condition; wheat allergy is characterized by a rapid IgE-dependent or -independent immune response and the basis of non-celiac wheat sensitivity is an innate immune response. Impairment in the epithelial barrier function is a common feature in gluten-related disorders. However, whether it is a primary condition within the pathophysiology of these diseases is still a matter of debate. The paper gives an overview of the reported barrier defects in gluten-related disorders and supports the hypothesis of a primary involvement of the epithelial barrier function in the development of those conditions. View this paper.
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Articles (290)

  • Article
  • Open Access
3 Citations
5,580 Views
13 Pages

21 October 2019

Though the association between sleep duration and obesity has been generally acknowledged, there is little information about the mechanisms behind this association. The purpose of this study was to examine the effect of the fat intake and stress vari...

  • Article
  • Open Access
87 Citations
12,174 Views
13 Pages

Water Extract of Curcuma longa L. Ameliorates Non-Alcoholic Fatty Liver Disease

  • Jeongeun Mun,
  • Shintae Kim,
  • Ho-Geun Yoon,
  • Yanghee You,
  • Ok-Kyung Kim,
  • Kyung-Chul Choi,
  • Yoo-Hyun Lee,
  • Jeongmin Lee,
  • Jeongjin Park and
  • Woojin Jun

21 October 2019

Our aim was to investigate whether hot water extract (CLW) of Curcuma longa L. could prevent non-alcoholic fatty liver disease (NAFLD). HepG2 cells were treated with free fatty acid (FFA) mixture (oleic acid: palmitic acid, 2:1) for 24 h to stimulate...

  • Article
  • Open Access
23 Citations
6,392 Views
16 Pages

21 October 2019

Diabetes mellitus is a non-communicable disease entity currently constituting one of the most significant health problems. The development of effective therapeutic strategies for the prevention and/or treatment of diabetes mellitus based on the selec...

  • Article
  • Open Access
1 Citations
4,315 Views
10 Pages

Gene Influence in the Effectiveness of Plant Sterols Treatment in Children: Pilot Interventional Study

  • Ismael San Mauro Martín,
  • Elena Garicano Vilar,
  • Sara Sanz Rojo,
  • Luis Collado Yurrita,
  • Eva Pérez Arruche,
  • Esperanza Arce Delgado and
  • Javier Andrés Blumenfeld Olivares

21 October 2019

Cardiovascular disease is linked to high serum low density lipoprotein (LDL)-cholesterol levels. Cardiovascular risk may be indirectly influenced by genetic load. Serum LDL-cholesterol levels may be reduced by the consumption of food enriched with pl...

  • Feature Paper
  • Article
  • Open Access
21 Citations
5,981 Views
10 Pages

The Effect of Vitamin D Supplementation on its Metabolism and the Vitamin D Metabolite Ratio

  • Vito Francic,
  • Stan R. Ursem,
  • Niek F. Dirks,
  • Martin H. Keppel,
  • Verena Theiler-Schwetz,
  • Christian Trummer,
  • Marlene Pandis,
  • Valentin Borzan,
  • Martin R. Grübler and
  • Nicolas D. Verheyen
  • + 5 authors

21 October 2019

25-hydroxyvitamin D (25(OH)D) is commonly measured to assess vitamin D status. Other vitamin D metabolites such as 24,25-dihydroxyvitamin D (24,25(OH)2D) provide additional insights into vitamin D status or metabolism. Earlier studies suggested that...

  • Article
  • Open Access
32 Citations
6,937 Views
16 Pages

21 October 2019

We examined the reproducibility and relative validity of two measures of overall diet quality, the Healthy Eating Index-2015 (HEI-2015) and Nutrient-Rich Food Index 9.3 (NRF9.3), as estimated by well-established self-administered dietary assessment q...

  • Article
  • Open Access
18 Citations
7,866 Views
14 Pages

Large Neutral Amino Acid Therapy Increases Tyrosine Levels in Adult Patients with Phenylketonuria: A Long-Term Study

  • Alessandro P. Burlina,
  • Chiara Cazzorla,
  • Pamela Massa,
  • Giulia Polo,
  • Christian Loro,
  • Daniela Gueraldi and
  • Alberto B. Burlina

21 October 2019

The standard treatment for phenylketonuria (PKU) is a lifelong low-phenylalanine (Phe) diet, supplemented with Phe-free protein substitutes; however, adult patients often show poor adherence to therapy. Alternative treatment options include the use o...

  • Article
  • Open Access
27 Citations
4,193 Views
13 Pages

Evaluation of a Technological Image-Based Dietary Assessment Tool for Children during Pubertal Growth: A Pilot Study

  • Jiao-Syuan Wang,
  • Rong-Hong Hsieh,
  • Yu-Tang Tung,
  • Yue-Hwa Chen,
  • Chen Yang and
  • Yang Ching Chen

20 October 2019

We designed an image-based dietary assessment tool called COFIT, which means “fit together” and pilot-tested it in the Taipei Puberty Longitudinal Study (TPLS). Children aged 6–17 years were invited to use COFIT over three days for...

  • Review
  • Open Access
31 Citations
18,661 Views
16 Pages

Effect of the Combination of Creatine Monohydrate Plus HMB Supplementation on Sports Performance, Body Composition, Markers of Muscle Damage and Hormone Status: A Systematic Review

  • Julen Fernández-Landa,
  • Julio Calleja-González,
  • Patxi León-Guereño,
  • Alberto Caballero-García,
  • Alfredo Córdova and
  • Juan Mielgo-Ayuso

20 October 2019

Although there are many studies showing the isolated effect of creatine monohydrate (CrM) and β-hydroxy β-methylbutyrate (HMB), it is not clear what effect they have when they are combined. The main purpose of this systematic review was to...

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Nutrients - ISSN 2072-6643