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Nutrients, Volume 11, Issue 11

November 2019 - 289 articles

Cover Story: Phenolic compounds are promising molecules for the prevention of neurodegenerative disorders. However, little is known about the ability of their main circulating metabolites, derived by their interaction with the gut microbiota, to reach the brain. The present work investigated the ability of phenyl--valerolactones, the main flavan-3-ol metabolites, to cross the blood-brain barrier. Five experimental models were used, with increased realism, including in silico, in vitro and in vivo animal studies. Results highlighted the blood-brain barrier permeability to one of the main flavan-3-ol microbial metabolites, namely 5-(hydroxyphenyl)-γ-valerolactone-sulfate. Further research is needed to better understand the underlying mechanism and the biological effect of this metabolite on brain cells. Nevertheless, these results help support the neuroprotective effects of phenolic-rich foods in the frame of the “gut-brain axis”.View the paper

Articles (289)

  • Article
  • Open Access
3 Citations
4,246 Views
12 Pages

Plasma versus Erythrocyte Vitamin E in Renal Transplant Recipients, and Duality of Tocopherol Species

  • Camilo G. Sotomayor,
  • Ramón Rodrigo,
  • António W. Gomes-Neto,
  • Juan Guillermo Gormaz,
  • Robert A. Pol,
  • Isidor Minović,
  • Manfred L. Eggersdorfer,
  • Michel Vos,
  • Ineke J. Riphagen and
  • Martin H. de Borst
  • + 4 authors

19 November 2019

Redox imbalance is an adverse on-going phenomenon in renal transplant recipients (RTR). Vitamin E has important antioxidant properties that counterbalance its deleterious effects. However, plasma vitamin E affinity with lipids challenges interpretati...

  • Article
  • Open Access
10 Citations
5,250 Views
16 Pages

19 November 2019

Previous studies have suggested that in the first decade of this century the incidence of gestational diabetes (GDM) in pregnancy rose worldwide. In the Cambridge Baby Growth Study cohort we observed that this temporal trend was associated with an in...

  • Editorial
  • Open Access
33 Citations
8,657 Views
3 Pages

19 November 2019

Dietary trace minerals are pivotal and hold a key role in numerous metabolic processes. Trace mineral deficiencies (except for iodine, iron, and zinc) do not often develop spontaneously in adults on ordinary diets; infants are more vulnerable because...

  • Article
  • Open Access
22 Citations
21,340 Views
26 Pages

Exercise Mitigates the Loss of Muscle Mass by Attenuating the Activation of Autophagy during Severe Energy Deficit

  • Marcos Martin-Rincon,
  • Alberto Pérez-López,
  • David Morales-Alamo,
  • Ismael Perez-Suarez,
  • Pedro de Pablos-Velasco,
  • Mario Perez-Valera,
  • Sergio Perez-Regalado,
  • Miriam Martinez-Canton,
  • Miriam Gelabert-Rebato and
  • Julian William Juan-Habib
  • + 2 authors

19 November 2019

The loss of skeletal muscle mass with energy deficit is thought to be due to protein breakdown by the autophagy-lysosome and the ubiquitin-proteasome systems. We studied the main signaling pathways through which exercise can attenuate the loss of mus...

  • Article
  • Open Access
30 Citations
7,380 Views
8 Pages

19 November 2019

Diet has gained attention as a risk factor for the development of rheumatoid arthritis (RA), especially with regards to food of animal origin, such as meat and dairy products. By using data from national patient registers and dietary data from a larg...

  • Communication
  • Open Access
56 Citations
9,888 Views
10 Pages

Impact of Vitamin D on Physical Efficiency and Exercise Performance—A Review

  • Michał Wiciński,
  • Dawid Adamkiewicz,
  • Monika Adamkiewicz,
  • Maciej Śniegocki,
  • Marta Podhorecka,
  • Paweł Szychta and
  • Bartosz Malinowski

19 November 2019

Vitamin D deficiency amongst athletes and the general population seems to be a prominent problem. The most recognized role of vitamin D is its regulation of calcium homeostasis; there is a strong relationship between vitamin D and bone health. Moreov...

  • Article
  • Open Access
43 Citations
9,181 Views
12 Pages

Evaluation of the Nutritional Quality of Breakfast Cereals Sold on the Italian Market: The Food Labelling of Italian Products (FLIP) Study

  • Donato Angelino,
  • Alice Rosi,
  • Margherita Dall’Asta,
  • Nicoletta Pellegrini and
  • Daniela Martini

19 November 2019

Breakfast cereals are present on the market as different types and, in general, are one of the food categories in which voluntary information, such as nutrition or health claims (NHC) or gluten free (GF) declarations, have the largest distribution. T...

  • Article
  • Open Access
28 Citations
6,465 Views
15 Pages

Dietary Patterns and Risk of Obesity and Early Childhood Caries in Australian Toddlers: Findings from an Australian Cohort Study

  • Lucinda K. Bell,
  • Celeste Schammer,
  • Gemma Devenish,
  • Diep Ha,
  • Murray W. Thomson,
  • John A. Spencer,
  • Loc G. Do,
  • Jane A. Scott and
  • Rebecca K. Golley

19 November 2019

We examined associations between dietary patterns at 12 months, characterised using multiple methodologies, and risk of obesity and early childhood caries (ECC) at 24–36 months. Participants were Australian toddlers (n = 1170) from the Study of...

  • Article
  • Open Access
51 Citations
8,125 Views
18 Pages

Investigation of Antibacterial and Antiinflammatory Activities of Proanthocyanidins from Pelargonium sidoides DC Root Extract

  • Aiste Jekabsone,
  • Inga Sile,
  • Andrea Cochis,
  • Marina Makrecka-Kuka,
  • Goda Laucaityte,
  • Elina Makarova,
  • Lia Rimondini,
  • Rasa Bernotiene,
  • Lina Raudone and
  • Evelina Vedlugaite
  • + 4 authors

19 November 2019

The study explores antibacterial, antiinflammatory and cytoprotective capacity of Pelargonium sidoides DC root extract (PSRE) and proanthocyanidin fraction from PSRE (PACN) under conditions characteristic for periodontal disease. Following previous f...

  • Article
  • Open Access
81 Citations
8,354 Views
14 Pages

Adherence to the Mediterranean Diet and Its Association with Body Composition and Physical Fitness in Spanish University Students

  • Ana Isabel Cobo-Cuenca,
  • Miriam Garrido-Miguel,
  • Alba Soriano-Cano,
  • Asunción Ferri-Morales,
  • Vicente Martínez-Vizcaíno and
  • Noelia María Martín-Espinosa

19 November 2019

The aims of this study were to assess the association of adherence to the Mediterranean diet (MD) with physical fitness and body composition in Spanish university students and to determine the ability to predict the MD adherence of each Mediterranean...

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Nutrients - ISSN 2072-6643Creative Common CC BY license