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75 Results Found

  • Article
  • Open Access
1 Citations
1,775 Views
19 Pages

The Impact of RObotic Assisted Rehabilitation on Trunk Control in Patients with Severe Acquired Brain Injury (ROAR-sABI)

  • Letizia Castelli,
  • Claudia Loreti,
  • Anna Maria Malizia,
  • Chiara Iacovelli,
  • Sabina Renzi,
  • Luca Fioravanti,
  • Vincenza Amoruso,
  • Ilaria Paolasso,
  • Francesca Di Caro and
  • Luca Padua
  • + 1 author

26 February 2025

Daily activities require balance and control posture. A severe Acquired Brain Injury (sABI) disrupts movement organization, control and execution, affecting trunk control and balance. Trunk control therapy for difficult patients requires known and no...

  • Study Protocol
  • Open Access
1,040 Views
20 Pages

Combined Robotic VErticalization and Lower Limb Mobilization in Patients with Severe Acquired Brain Injury: Protocol of a Multicenter Randomized Controlled Trial (VEM-sABI)

  • Anna Estraneo,
  • Maria Rosaria Fiorentino,
  • Alfonso Magliacano,
  • Maria Assunta Puopolo,
  • Ilaria Rivetti and
  • Maria Cristina Messa

20 September 2025

Background: Upright position recovery (i.e., verticalization) is crucial in the rehabilitation of severe acquired brain injury (sABI). VErticalization by tilt table equipped with robotic-assisted lower limbs cyclic Mobilization (VEM) may facilitate a...

  • Article
  • Open Access
10 Citations
3,752 Views
14 Pages

Moving toward Appropriate Motor Assessment Tools in People Affected by Severe Acquired Brain Injury: A Scoping Review with Clinical Advices

  • Mirjam Bonanno,
  • Rosaria De Luca,
  • William Torregrossa,
  • Paolo Tonin and
  • Rocco Salvatore Calabrò

Severe acquired brain injury (SABI) is among the leading causes of death and disability worldwide. Patients following SABI may develop motor, sensory and cognitive disorders, alone or in combination. This review aims to point out the most used scales...

  • Article
  • Open Access
1 Citations
2,269 Views
8 Pages

FunctionaL Assessment Scale of Hemianopia (FLASH): A New Multidisciplinary Tool to Assess Hemianopia in Patients with Severe Acquired Brain Injury

  • Susanna Lucatello,
  • Sara De Angelis,
  • Concetta Di Lorenzo,
  • Marco Iosa,
  • Luisa Magnotti,
  • Marta Di Paolo,
  • Maria De Luca,
  • Maria Gabriella Buzzi and
  • Marco Tramontano

2 November 2023

Background: Severe acquired brain injury (sABI) encompasses a range of neurological impairments. Visual dysfunction, particularly homonymous visual field defects (HVFDs) and homonymous hemianopia (HH), commonly afflicts sABI survivors, affecting thei...

  • Article
  • Open Access
13 Citations
3,092 Views
12 Pages

Critical Illness Polyneuropathy and Myopathy and Clinical Detection of the Recovery of Consciousness in Severe Acquired Brain Injury Patients with Disorders of Consciousness after Rehabilitation

  • Bahia Hakiki,
  • Francesca Cecchi,
  • Silvia Pancani,
  • Anna Maria Romoli,
  • Francesca Draghi,
  • Maenia Scarpino,
  • Raisa Sterpu,
  • Andrea Mannini,
  • Claudio Macchi and
  • Antonello Grippo

17 February 2022

Background: Disorders of consciousness (DoCs) include unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS). Critical illness polyneuropathy and myopathy (CIPNM) is frequent in severe acquired brain injuries and impacts function...

  • Article
  • Open Access
66 Citations
7,542 Views
18 Pages

Accuracy of EEG Biomarkers in the Detection of Clinical Outcome in Disorders of Consciousness after Severe Acquired Brain Injury: Preliminary Results of a Pilot Study Using a Machine Learning Approach

  • Francesco Di Gregorio,
  • Fabio La Porta,
  • Valeria Petrone,
  • Simone Battaglia,
  • Silvia Orlandi,
  • Giuseppe Ippolito,
  • Vincenzo Romei,
  • Roberto Piperno and
  • Giada Lullini

Accurate outcome detection in neuro-rehabilitative settings is crucial for appropriate long-term rehabilitative decisions in patients with disorders of consciousness (DoC). EEG measures derived from high-density EEG can provide helpful information re...

  • Article
  • Open Access
3 Citations
4,508 Views
10 Pages

Factors Influencing Functional Recovery during Rehabilitation after Severe Acquired Brain Injuries: A Retrospective Analysis

  • Paolo Finotti,
  • Massimo Iannilli,
  • Lucrezia Tognolo,
  • Claudia Vargiu,
  • Stefano Masiero and
  • Giovanni Antonio Checchia

18 October 2021

Severe acquired brain injuries (sABI) represent one of the main causes of disability and limitation in social life participation that need an intensive rehabilitation approach. The purpose of this study was to identify a possible correlation between...

  • Article
  • Open Access
6 Citations
2,315 Views
13 Pages

Relationship between Nutritional Risk, Clinical and Demographic Characteristics, and Pressure Ulcers in Patients with Severe Acquired Brain Injuries Attending a Rehabilitative Program

  • Chiara Francesca Gheri,
  • Luca Scalfi,
  • Barbara Biffi,
  • Silvia Pancani,
  • Sara Madiai,
  • Olivia Di Vincenzo,
  • Michele Ghaderi,
  • Rebecca Celoni,
  • Mara Dalladonna and
  • Francesca Draghi
  • + 6 authors

27 July 2023

Preliminary evidence in the literature suggests a high prevalence of malnutrition (undernutrition) in patients with severe acquired brain injuries (sABI), with an expected negative impact on clinical outcomes and pressure ulcers (PUs) in particular....

  • Case Report
  • Open Access
2 Citations
3,171 Views
10 Pages

Background: Augmentative and Alternative Communication (AAC) improved communicative skills in adults with post-stroke aphasia demonstrating the effectiveness in speech disorders and consequent improvement of patients’ communication skills. This...

  • Perspective
  • Open Access
1,090 Views
11 Pages

Systems of Care for Treating Severe Acquired Brain Injury: Comparing the United States to Italy

  • Nicholas J Cioe,
  • Rita Formisano,
  • Gregory O’Shanick,
  • Juliet Haarbauer-Krupa,
  • Valentina Bandiera,
  • Elisa Berardi,
  • Vincenzo Vinicola and
  • Umberto Bivona

29 August 2025

Acquired Brain Injury (ABI) is now widely regarded as a chronic condition but this change in conceptualization has not yet been realized in the way rehabilitation and care are offered and funded in the United States. Similarly, it is widely accepted...

  • Article
  • Open Access
9 Citations
2,830 Views
12 Pages

Severe Acquired Brain Injury: Prognostic Factors of Discharge Outcome in Older Adults

  • Augusto Fusco,
  • Caterina Galluccio,
  • Letizia Castelli,
  • Costanza Pazzaglia,
  • Roberta Pastorino,
  • Denise Pires Marafon,
  • Roberto Bernabei,
  • Silvia Giovannini and
  • Luca Padua

12 September 2022

Severe Acquired Brain Injury (sABI) is a leading cause of disability and requires intensive rehabilitation treatment. Discharge from the rehabilitation ward is a key moment in patient management. Delays in patient discharge can adversely affect hospi...

  • Article
  • Open Access
2 Citations
1,665 Views
10 Pages

Impact of Multidrug-Resistant Organisms on Severe Acquired Brain Injury Rehabilitation: An Observational Study

  • Giovanna Barbara Castellani,
  • Elisa Maietti,
  • Valentina Colombo,
  • Stefano Clemente,
  • Ivo Cassani and
  • Paola Rucci

Healthcare-associated infections (HAIa) and antimicrobial resistance are expected to be the next threat to human health and are most frequent in people with severe acquired brain injury (SABI), who can be more easily colonized by multidrug-resistant...

  • Article
  • Open Access
8 Citations
4,676 Views
12 Pages

From Shunt to Recovery: A Multidisciplinary Approach to Hydrocephalus Treatment in Severe Acquired Brain Injury Rehabilitation

  • Giovanna B. Castellani,
  • Giovanni Miccoli,
  • Francesca C. Cava,
  • Pamela Salucci,
  • Valentina Colombo,
  • Elisa Maietti and
  • Giorgio Palandri

21 December 2021

Background: Hydrocephalus among Severe Acquired Brain Injury (SABI) patients remains overlooked during rehabilitation. Methods: A retrospective cohort study was carried out of traumatic and non-traumatic SABI patients with hydrocephalus, consecutivel...

  • Article
  • Open Access
4 Citations
3,324 Views
10 Pages

Central-nervous-system (CNS) injuries constitute a significant cause of morbidity (often resulting in long-term disability) and mortality. This cross-sectional study compared the activity and participation of community-dwelling people with severe dis...

  • Article
  • Open Access
1 Citations
3,226 Views
9 Pages

Electrophysiological Screening to Assess Foot Drop Syndrome in Severe Acquired Brain Injury in Rehabilitative Settings

  • Francesco Piccione,
  • Antonio Cerasa,
  • Paolo Tonin,
  • Simone Carozzo,
  • Rocco Salvatore Calabrò,
  • Stefano Masiero and
  • Lucia Francesca Lucca

Background: Foot drop syndrome (FDS), characterized by severe weakness and atrophy of the dorsiflexion muscles of the feet, is commonly found in patients with severe acquired brain injury (ABI). If the syndrome is unilateral, the cause is often a per...

  • Study Protocol
  • Open Access
2,515 Views
10 Pages

A New Clinical Protocol for a Timely Diagnosis and Treatment of Hydrocephalus in Patients with Severe Acquired Brain Injury

  • Francesca Cesira Cava,
  • Giovanna Barbara Castellani,
  • Elisa Maietti,
  • Pamela Salucci,
  • Valentina Colombo and
  • Giorgio Palandri

Background: Secondary hydrocephalus is a well-known complication of severe acquired brain injuries (sABIs) often diagnosed during inpatient rehabilitation. Currently, there is no gold standard for its detection. Therefore, we designed a novel clinica...

  • Article
  • Open Access
3 Citations
3,913 Views
14 Pages

Is Virtual Reality Orientation Therapy Useful to Optimize Cognitive and Behavioral Functioning Following Severe Acquired Brain Injury? An Exploratory Study

  • Rosaria De Luca,
  • Andrea Calderone,
  • Antonio Gangemi,
  • Carmela Rifici,
  • Mirjam Bonanno,
  • Maria Grazia Maggio,
  • Irene Cappadona,
  • Isabella Veneziani,
  • Augusto Ielo and
  • Francesco Corallo
  • + 3 authors

Introduction: Severe acquired brain injury (SABI) is a leading cause of death and disability, and it is defined as a brain injury that occurs after birth due to traumatic or non-traumatic causes. Reality orientation therapy (ROT) uses repeated time&n...

  • Article
  • Open Access
6 Citations
2,918 Views
17 Pages

Little is known about service actions delivered in the complex intervention of vocational rehabilitation (VR) for people with severe acquired brain injury (ABI). Scale-up of the Vocational Intervention Program (VIP) across the 12 Community teams of t...

  • Article
  • Open Access
11 Citations
3,378 Views
12 Pages

Humanoid Robot Use in Cognitive Rehabilitation of Patients with Severe Brain Injury: A Pilot Study

  • Francesco Corallo,
  • Giuseppa Maresca,
  • Caterina Formica,
  • Lilla Bonanno,
  • Alessia Bramanti,
  • Nicholas Parasporo,
  • Fabio Mauro Giambò,
  • Maria Cristina De Cola and
  • Viviana Lo Buono

23 May 2022

Severe acquired brain injury (SABI) is a major global public health problem and a source of disability. A major contributor to disability after SABI is limited access to multidisciplinary rehabilitation, despite evidence of sustained functional gains...

  • Article
  • Open Access
2 Citations
2,940 Views
21 Pages

10 February 2023

The diagnosis of apathy, one of the most common behavioral changes after acquired brain injury (ABI), is important for improving clinical understanding and treatment of persons with ABI. The main aim of this study was to determine the possible role o...

  • Article
  • Open Access
7 Citations
2,245 Views
10 Pages

Is the “Family Glass Cabin” Useful to Safely Allow Inpatient–Caregiver Interaction in the COVID-19 Era? A Pilot Study on Severe Acquired Brain Injury

  • Rosaria De Luca,
  • Carmela Rifici,
  • Patrizia Pollicino,
  • Sergio Parisi,
  • Mirjam Bonanno,
  • William Torregrossa,
  • Donatella Ferrara,
  • Angelo Caminiti,
  • Marco Piccione and
  • Rocco Salvatore Calabrò
  • + 1 author

15 March 2022

Acquired Brain Injury (ABI) is a life-changing event that can have a devastating impact on all aspects of a person’s functioning. Patients with ABI present several behavioral problems that have worsened during the COVID-19 pandemic. This study...

  • Article
  • Open Access
1,226 Views
14 Pages

Emotional Status in Relation to Metacognitive Self-Awareness and Level of Functional Disability Following Acquired Brain Injury

  • Valentina Bandiera,
  • Dolores Villalobos,
  • Alberto Costa,
  • Gaia Galluzzi,
  • Alessia Quinzi,
  • Arianna D’Aprile and
  • Umberto Bivona

Background/Objectives: Impairment in self-awareness (ISA) is one of the common consequences of an acquired brain injury (ABI) and is associated with anosodiaphoria. Collectively, these co-occurring neuropsychological disorders pose significant obstac...

  • Article
  • Open Access
3 Citations
5,396 Views
11 Pages

Oxcarbazepine for Behavioral Disorders after Brain Injury: Factors Influencing Efficacy

  • Marco Pozzi,
  • Paolo Avantaggiato,
  • Valentina Pastore,
  • Carla Carnovale,
  • Emilio Clementi and
  • Sandra Strazzer

Carbamazepine and oxcarbazepine are used for behavioral disorders following organic diseases. After severe acquired brain injury, patients may develop frontal symptoms. In our neurological rehabilitation routine, oxcarbazepine is used for better safe...

  • Article
  • Open Access
5 Citations
2,805 Views
12 Pages

The Immediate Effects of Immersive Virtual Reality on Autonomic Nervous System Function in Patients with Disorders of Consciousness after Severe Acquired Brain Injury: A Pilot Study

  • Giuseppe Reale,
  • Augusto Fusco,
  • Rossella Calciano,
  • Noemi Vallario,
  • Gabriele Vagnarelli,
  • Pietro Caliandro,
  • Letizia Castelli,
  • Marco Moci,
  • Gaetano Tieri and
  • Luigi Iasevoli
  • + 1 author

12 December 2023

Disorders of Consciousness (DoCs) after severe acquired brain injury involve substantial impairment of cognition and physical functioning, requiring comprehensive rehabilitation and support. Technological interventions, such as immersive Virtual Real...

  • Article
  • Open Access
22 Citations
4,402 Views
12 Pages

Virtual Reality and Lower Limb Rehabilitation: Effects on Motor and Cognitive Outcome—A Crossover Pilot Study

  • Augusto Fusco,
  • Silvia Giovannini,
  • Letizia Castelli,
  • Daniele Coraci,
  • Dario Mattia Gatto,
  • Giuseppe Reale,
  • Roberta Pastorino and
  • Luca Padua

20 April 2022

The effectiveness of virtual reality (VR) in the motor and cognitive rehabilitation of patients with severe acquired brain injury (sABI) is unclear. This randomized, controlled, crossover, single-blinded, pilot study investigates the cognitive and mo...

  • Article
  • Open Access
586 Views
16 Pages

Confusion Assessment Protocol: Italian Cross-Cultural Adaptation and Validation

  • Giulia Ferri,
  • Anna Carannante,
  • Manuela Iannetti,
  • Sara Schiattone,
  • Paola Ciurli,
  • Fabiana Mogavero,
  • Valentina Massimi,
  • Marta Aloisi,
  • Rita Formisano and
  • Marco Giustini

13 October 2025

Background: This study validated the Italian version of the Confusion Assessment Protocol (CAP), a tool designed to assess Post-Traumatic Confusional State (PTCS) in patients with severe acquired brain injury (sABI) who are not evaluable with standar...

  • Article
  • Open Access
9 Citations
4,376 Views
31 Pages

Multimodal Neuromonitoring and Neurocritical Care in Swine to Enhance Translational Relevance in Brain Trauma Research

  • John C. O’Donnell,
  • Kevin D. Browne,
  • Svetlana Kvint,
  • Leah Makaron,
  • Michael R. Grovola,
  • Saarang Karandikar,
  • Todd J. Kilbaugh,
  • D. Kacy Cullen and
  • Dmitriy Petrov

Neurocritical care significantly impacts outcomes after moderate-to-severe acquired brain injury, but it is rarely applied in preclinical studies. We created a comprehensive neurointensive care unit (neuroICU) for use in swine to account for the infl...

  • Feature Paper
  • Article
  • Open Access
1 Citations
3,032 Views
15 Pages

Confused about Rehabilitation? Multi-Faceted Approaches for Brain Injured Patients in a Confusional State

  • Jesper Fabricius,
  • Anna Birthe Andersen,
  • Gitte Lindegård Munk and
  • Hanne Kaae Kristensen

Post-injury confusional state is a common phenomenon following acquired brain injury. A multi-faceted approach for decreasing confusion is recommended, but there is a paucity of research related to non-pharmacological management. The main objective w...

  • Article
  • Open Access
6 Citations
2,308 Views
12 Pages

Long-Term Vocational Outcome at 15 Years from Severe Traumatic and Non-Traumatic Brain Injury in Pediatric Age

  • Sandra Strazzer,
  • Valentina Pastore,
  • Susanna Frigerio,
  • Katia Colombo,
  • Sara Galbiati,
  • Federica Locatelli and
  • Susanna Galbiati

Background: Recent studies suggest that acquired brain injury with impaired consciousness in infancy is related to more severe and persistent effects and may have a cumulative effect on ongoing development. In this work, we aim to describe vocational...

  • Review
  • Open Access
96 Citations
16,135 Views
31 Pages

Understanding Acquired Brain Injury: A Review

  • Liam Goldman,
  • Ehraz Mehmood Siddiqui,
  • Andleeb Khan,
  • Sadaf Jahan,
  • Muneeb U Rehman,
  • Sidharth Mehan,
  • Rajat Sharma,
  • Stepan Budkin,
  • Shashi Nandar Kumar and
  • Ankita Sahu
  • + 2 authors

Any type of brain injury that transpires post-birth is referred to as Acquired Brain Injury (ABI). In general, ABI does not result from congenital disorders, degenerative diseases, or by brain trauma at birth. Although the human brain is protected fr...

  • Review
  • Open Access
3 Citations
4,111 Views
14 Pages

Neurodegenerative Disorders in the Context of Vascular Changes after Traumatic Brain Injury

  • Zahra Hasanpour-Segherlou,
  • Forough Masheghati,
  • Mahdieh Shakeri-Darzehkanani,
  • Mohammad-Reza Hosseini-Siyanaki and
  • Brandon Lucke-Wold

6 September 2024

Traumatic brain injury (TBI) results from external biomechanical forces that cause structural and physiological disturbances in the brain, leading to neuronal, axonal, and vascular damage. TBIs are predominantly mild (65%), with moderate (10%) and se...

  • Article
  • Open Access
13 Citations
3,673 Views
12 Pages

The Role of Technological Rehabilitation in Patients with Intensive Care Unit Weakness: A Randomized Controlled Pilot Study

  • Letizia Castelli,
  • Chiara Iacovelli,
  • Augusto Fusco,
  • Vincenza Amoruso,
  • Cristina Cuccagna,
  • Claudia Loreti,
  • Silvia Giovannini and
  • Luca Padua

30 March 2023

Intensive-Care-Unit-Acquired Weakness (ICU-AW) is the most common neuromuscular impairment in critically ill patients and can have a significant impact on long-term disability. Early rehabilitation has been suggested to facilitate the natural recover...

  • Article
  • Open Access
5 Citations
5,476 Views
12 Pages

The purpose of this pilot study was to explore and interpret the way that individuals with acquired brain injury, admitted to inpatient neurorehabilitation with severe eating difficulties, experienced eating nine to fifteen months after discharge. Fo...

  • Article
  • Open Access
20 Citations
4,090 Views
12 Pages

One-Year Demographical and Clinical Indices of Patients with Chronic Disorders of Consciousness

  • Julia Nekrasova,
  • Mikhail Kanarskii,
  • Ilya Borisov,
  • Pranil Pradhan,
  • Denis Shunenkov,
  • Alexey Vorobiev,
  • Maria Smirnova,
  • Vera Pasko,
  • Marina V. Petrova and
  • Elena Luginina
  • + 1 author

This work aims to evaluate the prognostic value of the demographical and clinical data on long-term outcomes (up to 12 months) in patients with severe acquired brain injury with vegetative state/unresponsive wakefulness syndrome (VS/UWS/UWS) or a min...

  • Review
  • Open Access
4 Citations
4,419 Views
13 Pages

Coping Strategies in Patients with Acquired Brain Injury: A Scoping Review

  • Davide Cardile,
  • Andrea Calderone,
  • Maria Pagano,
  • Irene Cappadona,
  • Carmela Rifici,
  • Angelo Quartarone,
  • Francesco Corallo and
  • Rocco Salvatore Calabrò

In recent years, there has been marked interest in looking at the psychological consequences of medical conditions, such as traumatic or acquired brain injuries. Coping strategies are essential for clinical recovery and for dealing with the stressful...

  • Article
  • Open Access
4 Citations
2,931 Views
15 Pages

Brain Injury Is Prevalent and Precedes Tobacco Use among Youth and Young Adults Experiencing Homelessness

  • Julianna M. Nemeth,
  • Allison M. Glasser,
  • Alice Hinton,
  • Joseph M. Macisco,
  • Amy Wermert,
  • Raya Smith,
  • Hannah Kemble and
  • Georgia Sasser

70%+ of youth and young adults experiencing homelessness (YYEH; 14–24 years old) smoke combustible tobacco. Little is known about the prevalence of acquired brain injury (ABI) among youth and young adult smokers experiencing homelessness (YYSEH...

  • Case Report
  • Open Access
1,832 Views
11 Pages

Transient Worsening of Dysphagia and Dysarthria after Treatment with Botulinum Toxin in Patients with Acquired Brain Injury

  • Lucia Francesca Lucca,
  • Luisa Spezzano,
  • Francesco Bono,
  • Maria Ursino,
  • Antonio Cerasa and
  • Francesco Piccione

7 December 2023

Although botulinum toxin is widely considered an effective and safe treatment for a variety of neurological conditions (such as disabling spasticity), local or systemic adverse effects have often been reported. This study describes three cases of pat...

  • Review
  • Open Access
98 Citations
17,557 Views
17 Pages

18 March 2019

Traumatic brain injury (TBI) and its potential long-term consequences are of major concern for public health. Neurorehabilitation of affected individuals has some specific characteristics in contrast to neurorehabilitation of patients with acquired b...

  • Systematic Review
  • Open Access
16 Citations
4,051 Views
21 Pages

19 April 2023

Acquired motor limits can be provoked by neurological lesions. Independently of the aetiologies, the lesions require patients to develop new coping strategies and adapt to the changed motor functionalities. In all of these occasions, what is defined...

  • Article
  • Open Access
7 Citations
5,164 Views
17 Pages

8 September 2020

Cognitive impairment is the most common sequelae following an acquired brain injury (ABI) and can have profound impact on the life and rehabilitation potential for the individual. The literature demonstrates that music training results in a musician&...

  • Article
  • Open Access
10 Citations
3,742 Views
12 Pages

Impact of Cranioplasty on Rehabilitation Course of Patients with Traumatic or Hemorrhagic Brain Injury

  • Chiara Mele,
  • Anna Bassetto,
  • Valentina Boetto,
  • Antonio Nardone and
  • Valeria Pingue

31 December 2022

Background: Some authors have hypothesized that cranioplasty after decompressive craniectomy (DC) could positively influence functional recovery through several mechanisms. However, only a few studies with small sample sizes have investigated the eff...

  • Article
  • Open Access
3 Citations
1,491 Views
11 Pages

Free Thyroxine (fT4) as a Potential Biomarker of Neurological and Functional Outcome in Acquired Brain Injury: A Prospective Multicenter Cohort Study

  • Chiara Mele,
  • Sergio Bagnato,
  • Antonio De Tanti,
  • Lucia Francesca Lucca,
  • Donatella Saviola,
  • Laura Marcuccio,
  • Pasquale Moretta,
  • Federico Scarponi,
  • Ernesto Losavio and
  • Emilia Picciola
  • + 1 author

30 November 2023

The potential involvement of thyroid hormones (THs) in the neurological and functional recovery of patients with brain damage has been hypothesized. We aimed at investigating the role of THs and their variations during the rehabilitation process as p...

  • Article
  • Open Access
4 Citations
4,333 Views
21 Pages

Brain Extraction Methods in Neonatal Brain MRI and Their Effects on Intracranial Volumes

  • Tânia F. Vaz,
  • Nuno Canto Moreira,
  • Lena Hellström-Westas,
  • Nima Naseh,
  • Nuno Matela and
  • Hugo A. Ferreira

6 February 2024

Magnetic resonance imaging (MRI) plays an important role in assessing early brain development and injury in neonates. When using an automated volumetric analysis, brain tissue segmentation is necessary, preceded by brain extraction (BE) to remove non...

  • Article
  • Open Access
4 Citations
2,032 Views
16 Pages

White Matter Metabolite Ratios Predict Cognitive Outcome in Pediatric Traumatic Brain Injury

  • Luke Berger,
  • Barbara Holshouser,
  • Joy G. Nichols,
  • Jamie Pivonka-Jones,
  • Stephen Ashwal and
  • Brenda Bartnik-Olson

The prognostic ability of global white matter and gray matter metabolite ratios following pediatric traumatic brain injury (TBI) and their relationship to 12-month neuropsychological assessments of intelligence quotient (IQ), attention, and memory is...

  • Article
  • Open Access
6 Citations
3,819 Views
19 Pages

Predictive Factors of Self-Reported Quality of Life in Acquired Brain Injury: One-Year Follow-Up

  • Alba Aza,
  • Miguel Á. Verdugo,
  • María Begoña Orgaz,
  • Antonio M. Amor and
  • María Fernández

Background: The sequelae and disabilities that follow an acquired brain injury (ABI) may negatively affect quality of life (QoL). The main objective of the study is to describe the QoL after an ABI and identify the predictors of a better QoL. Methods...

  • Case Report
  • Open Access
1 Citations
2,192 Views
10 Pages

5 December 2024

Traumatic direct type carotid cavernous fistula (CCF) is an acquired arteriovenous shunt between the carotid artery and the cavernous sinus post severe craniofacial trauma or iatrogenic injury. We reported a 46-year-old woman who had developed a trau...

  • Article
  • Open Access
2 Citations
2,763 Views
12 Pages

Translation and Transcultural Adaptation of the Wessex Head Injury Matrix, Italian Version: A Preliminary Report

  • Francesca Pistoia,
  • Agnes Shiel,
  • Raffaele Ornello,
  • Gennaro Saporito,
  • Luca Gentili,
  • Antonio Carolei,
  • Carmine Marini,
  • Simona Sacco and
  • Franco Marinangeli

Background: Patients who are in a coma, a vegetative state or a minimally conscious state present a clinical challenge for neurological assessment, which is a prerequisite for establishing a prognosis and planning management. Several scales have been...

  • Article
  • Open Access
572 Views
11 Pages

Tractography-Based Asymmetries in Acquired Brain Injury: Contributions to the Neuropsychological Profile and Rehabilitation in a Case-Series

  • Rosario Bordón Guerra,
  • Wenceslao Peñate Castro,
  • Eilin Ferreiro Díaz-Velis,
  • Coralia Sosa Pérez,
  • Sara Bisshopp Alfonso,
  • María Hernández Hernández,
  • José Luis Hernández Fleta and
  • Jesús Morera Molina

28 October 2025

Background: Acquired brain injury (ABI) often produces heterogeneous cognitive and emotional outcomes that are not fully explained by conventional neuropsychological testing. Diffusion tensor imaging (DTI) tractography may capture patient-specific pa...

  • Systematic Review
  • Open Access
11 Citations
3,842 Views
13 Pages

Use of Virtual Reality in Patients with Acquired Brain Injury: A Systematic Review

  • Andrea Calderone,
  • Diamante Carta,
  • Davide Cardile,
  • Angelo Quartarone,
  • Carmela Rifici,
  • Rocco Salvatore Calabrò and
  • Francesco Corallo

14 December 2023

Background and Objectives: ABI is found in all societies as the most severe, disabling neurological disorder. A cognitive rehabilitation program is essential for the clinical recovery of these patients, improving functional outcomes and quality of li...

  • Review
  • Open Access
614 Views
14 Pages

12 November 2025

Background/Objectives: This narrative review examines how developmentally appropriate safety and health education interventions in early childhood settings impact the incidence and severity of pediatric conditions requiring neurosurgical intervention...

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