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82 Results Found

  • Review
  • Open Access
4 Citations
3,065 Views
12 Pages

29 June 2024

Breast sensation plays a significant role in the safety and quality of life of women who undergo mastectomy and reconstruction. In 1992, Slezak et al. introduced the concept of abdominal flap neurotization to improve sensation of the reconstructed br...

  • Review
  • Open Access
23 Citations
8,239 Views
22 Pages

Corneal Neurotization—Indications, Surgical Techniques and Outcomes

  • Diana Carmen Dragnea,
  • Iva Krolo,
  • Carina Koppen,
  • Callum Faris,
  • Bert Van den Bogerd and
  • Sorcha Ní Dhubhghaill

13 March 2023

Corneal neurotization is a promising surgical approach for the treatment of moderate to severe neurotrophic keratopathy. This technique aims to restore corneal sensation by transferring healthy nerves, either directly or via a conduit, to the anesthe...

  • Review
  • Open Access
4 Citations
1,637 Views
12 Pages

Corneal Neurotization, Recent Progress, and Future Perspectives

  • Ovidiu Samoilă,
  • Lăcrămioara Samoilă and
  • Lorina Petrescu

Neurotrophic keratopathy (NK) is a rare degenerative disease caused by impairment of the trigeminal nerve, leading to corneal anesthesia, epithelial breakdown, and progressive vision loss. Conventional treatments primarily focus on symptom management...

  • Systematic Review
  • Open Access
1,470 Views
14 Pages

3 August 2025

Background: Breast reconstruction post-mastectomy has increasingly emphasized the importance of sensory restoration. This study aimed to evaluate the comparative efficacy of anterior versus lateral cutaneous intercostal nerve branches in neurotizatio...

  • Review
  • Open Access
4 Citations
2,067 Views
14 Pages

Insights on the Choice and Preparation of the Donor Nerve in Corneal Neurotization for Neurotrophic Keratopathy: A Narrative Review

  • Pietro Luciano Serra,
  • Giuseppe Giannaccare,
  • Alberto Cuccu,
  • Federico Bolognesi,
  • Federico Biglioli,
  • Marco Marcasciano,
  • Filippo Tarabbia,
  • Domenico Pagliara,
  • Andrea Figus and
  • Filippo Boriani

14 April 2024

The article introduces neurotrophic keratopathy (NK), a condition resulting from corneal denervation due to various causes of trigeminal nerve dysfunctions. Surgical techniques for corneal neurotization (CN) have evolved, aiming to restore corneal se...

  • Review
  • Open Access
6 Citations
6,306 Views
18 Pages

29 March 2022

When ulnar nerve lesions happen above the wrist level, sensation recovery after acute repair or nerve grafting is often challenging. Distal sensory nerve transfers may be an option for overcoming these sequelae. However, little data has been publishe...

  • Perspective
  • Open Access
3 Citations
2,066 Views
8 Pages

Hopeless Neuroma—The Neurotized Free Flap Tissue Augmentation as Salvage Therapy—A Concept and Clinical Demonstration

  • Martin Aman,
  • Julia J. Glaser,
  • Arne H. Boecker,
  • Mirjam Thielen,
  • Amr Eisa,
  • Amir K. Bigdeli,
  • Emre Gazyakan,
  • Ulrich Kneser and
  • Leila Harhaus

10 February 2023

Therapy-resistant neuroma pain is a devastating condition for patients and surgeons. Although various methods are described to surgically deal with neuromas, some discontinuity and stump neuroma therapies have anatomical limitations. It is widely kno...

  • Article
  • Open Access
9 Citations
2,513 Views
16 Pages

Vascularization of Poly-ε-Caprolactone-Collagen I-Nanofibers with or without Sacrificial Fibers in the Neurotized Arteriovenous Loop Model

  • Simon Kratzer,
  • Andreas Arkudas,
  • Marcus Himmler,
  • Dirk W. Schubert,
  • Dominik Schneidereit,
  • Julian Bauer,
  • Oliver Friedrich,
  • Raymund E. Horch and
  • Aijia Cai

25 November 2022

Electrospun nanofibers represent an ideal matrix for the purpose of skeletal muscle tissue engineering due to their highly aligned structure in the nanoscale, mimicking the extracellular matrix of skeletal muscle. However, they often consist of high-...

  • Review
  • Open Access
15 Citations
4,823 Views
10 Pages

The Evolution of Implant-Based Breast Reconstruction: Innovations, Trends, and Future Directions

  • Chris Amro,
  • Thomas J. Sorenson,
  • Carter J. Boyd,
  • Kshipra Hemal,
  • Nicholas A. Vernice,
  • Jenn J. Park,
  • Oriana D. Cohen,
  • Mihye Choi and
  • Nolan S. Karp

5 December 2024

Background/Objectives: Implant-based breast reconstruction has been essential since the 1960s, offering a faster and less invasive alternative to autologous reconstruction. Recent innovations—including direct-to-implant (DTI) reconstruction, ad...

  • Review
  • Open Access
1 Citations
3,204 Views
10 Pages

24 September 2024

Introduction: Reconstructive plastic surgeons have made great strides in the field of breast reconstruction to achieve the best results for patients undergoing treatment for breast cancer. As microsurgical techniques have evolved, these patients can...

  • Article
  • Open Access
578 Views
12 Pages

Sensory Recovery After Free Muscle Flap Reconstruction—A Clinical Study of Protective and Discriminative Function of Free Gracilis and Latissimus Dorsi Muscle Flaps Without Neurotization

  • Maximilian C. Stumpfe,
  • Moritz Billner,
  • Marc Hellweg,
  • Maximilian Hirschmann,
  • Rakan R. Al-Turki,
  • Celena A. Sörgel,
  • Vadym Burchak,
  • Nikolaus Wachtel and
  • Denis Ehrl

7 November 2025

Background/Objectives: Free gracilis (GM) and latissimus dorsi muscle (LDM) flaps are reliable options for complex defect coverage, but long-term sensory outcomes remain underexplored. Sensory impairment, especially the loss of protective cutaneous s...

  • Article
  • Open Access
22 Citations
11,805 Views
16 Pages

The Emotion Regulation Mechanism in Neurotic Individuals: The Potential Role of Mindfulness and Cognitive Bias

  • Ling Chen,
  • Xiqin Liu,
  • Xiangrun Weng,
  • Mingzhu Huang,
  • Yuhan Weng,
  • Haoran Zeng,
  • Yifan Li,
  • Danna Zheng and
  • Caiqi Chen

Neuroticism is a personality trait that impacts daily life and raises the risk of mental problems and physical illnesses. To understand the emotion regulation mechanism of neurotic individuals, we developed two complementary studies to examine the ef...

  • Review
  • Open Access
4 Citations
5,138 Views
19 Pages

Emerging Treatments for Persistent Corneal Epithelial Defects

  • Jeonghyun (Esther) Kwon,
  • Christie Kang,
  • Amirhossein Moghtader,
  • Sumaiya Shahjahan,
  • Zahra Bibak Bejandi,
  • Ahmad Alzein and
  • Ali R. Djalilian

1 April 2025

Persistent corneal epithelial defects (PCEDs) are a challenging ocular condition characterized by the failure of complete corneal epithelial healing after an insult or injury, even after 14 days of standard care. There is a lack of therapeutics that...

  • Review
  • Open Access
373 Views
16 Pages

Hot Topics in Implant-Based Breast Reconstruction

  • Thomas J. Sorenson,
  • Carter J. Boyd and
  • Nolan S. Karp

29 December 2025

Implant-based breast reconstruction (IBBR) remains the most common form of post-mastectomy reconstruction worldwide, offering patients a reliable and accessible option to restore breast contour. Advances in surgical technique, biomaterials, and impla...

  • Article
  • Open Access
16 Citations
7,735 Views
23 Pages

1 April 2022

Neuroticism has recently received increased attention in the psychology field due to the finding of high implications of neuroticism on an individual’s life and broader public health. This study aims to investigate the effect of a brief 6-week...

  • Article
  • Open Access
8 Citations
3,918 Views
15 Pages

Suicidal Ideation in Iraqi Medical Students Based on Research Using PHQ-9 and SSI-C

  • Ahmed Al-Imam,
  • Marek A. Motyka,
  • Beata Hoffmann,
  • Safwa Basil and
  • Nesif Al-Hemiary

Suicidal ideation is a spectrum of contemplations, wishes, and preoccupations with suicide. Its prevalence is ambiguous in Iraq, especially among the youth. We aim to survey the prevalence of suicidal ideation among Iraqi students and explore its ris...

  • Review
  • Open Access
15 Citations
5,253 Views
16 Pages

The Role of Sensory Innervation in Homeostatic and Injury-Induced Corneal Epithelial Renewal

  • Konstantin Feinberg,
  • Kiana Tajdaran,
  • Kaveh Mirmoeini,
  • Simeon C. Daeschler,
  • Mario A. Henriquez,
  • Katelyn E. Stevens,
  • Chilando M. Mulenga,
  • Arif Hussain,
  • Pedram Hamrah and
  • Gregory H. Borschel
  • + 2 authors

9 August 2023

The cornea is the window through which we see the world. Corneal clarity is required for vision, and blindness occurs when the cornea becomes opaque. The cornea is covered by unique transparent epithelial cells that serve as an outermost cellular bar...

  • Article
  • Open Access
18 Citations
3,875 Views
25 Pages

Activation of Adrenal Steroidogenesis and an Improvement of Mood Balance in Postmenopausal Females after Spa Treatment Based on Physical Activity

  • Pavla Honců,
  • Martin Hill,
  • Marie Bičíková,
  • Dobroslava Jandová,
  • Marta Velíková,
  • Jiří Kajzar,
  • Lucie Kolátorová,
  • Jiří Bešťák,
  • Ludmila Máčová and
  • Ľuboslav Stárka
  • + 3 authors

Spa treatment can effectively reestablish mood balance in patients with psychiatric disorders. In light of the adrenal gland’s role as a crossroad of psychosomatic medicine, this study evaluated changes in 88 circulating steroids and their rela...

  • Article
  • Open Access
1 Citations
2,183 Views
9 Pages

22 November 2022

Birth defects (BDs) are an important cause of abortion, stillbirth, and infant mortality that may cause lifelong disability. The defects can be caused by genetics, environmental exposure, or maternal chronic diseases. We conducted a study to analyze...

  • Article
  • Open Access
6 Citations
2,945 Views
13 Pages

25 January 2023

Doubtless, the COVID-19 pandemic has been extremely challenging in all aspects. However, rather than looking at COVID-19 exclusively as a catastrophic event, which has generated insecurity, anxiety, panic and helplessness, I suggest investigating thi...

  • Article
  • Open Access
1,880 Views
24 Pages

Narcissism and Anti-Immigrant Attitudes: A Tale of Pride and Prejudice?

  • Virgil Zeigler-Hill,
  • Angelina Toma,
  • Emily Thomas and
  • Avi Besser

1 April 2025

Narcissism has been linked to negative attitudes toward certain outgroups. The present studies examined the associations that narcissistic traits—extraverted narcissism, antagonistic narcissism, and neurotic narcissism—had with anti-immig...

  • Article
  • Open Access
10 Citations
3,245 Views
11 Pages

28 January 2023

Post-traumatic stress disorder (PTSD) is a pathological condition that may lead to a significant deterioration in the quality of life over time. Therefore, the study of the elements that can characterize the disorder could be considered of great clin...

  • Article
  • Open Access
4,388 Views
22 Pages

We examined the connections that narcissistic and borderline personality traits had with hypothetical responses to romantic infidelity in a sample of Israeli community members (N = 997). We distinguished between four forms of narcissism: extraverted...

  • Review
  • Open Access
5 Citations
7,669 Views
15 Pages

Aboriginals of Latin America have used DMT (N,N-dimethyltryptamine) in ritualistic ceremonies for centuries. Nevertheless, there are limited data on web users’ interest concerning DMT. We aim to review the literature and explore the spatial&nda...

  • Article
  • Open Access
17 Citations
5,078 Views
12 Pages

12 June 2022

Background: The authors previously developed deep-learning models for the prediction of colorectal polyp histology (advanced colorectal cancer, early cancer/high-grade dysplasia, tubular adenoma with or without low-grade dysplasia, or non-neoplasm) f...

  • Article
  • Open Access
229 Views
16 Pages

Total Quadriceps Resection in High-Grade Soft-Tissue Sarcomas of the Thigh: Surgical Technique and Long-Term Functional Outcomes in Surviving Patients

  • Luis Rafael Ramos Pascua,
  • Paula Casas Ramos,
  • Rubén Álvarez García,
  • Sergio Sánchez Herráez,
  • Cristina Ojeda Thies,
  • Maximiliano Eugenio Negri,
  • Daniel Bustamante Recuenco and
  • Jesús Enrique Vilá Rico

22 December 2025

Background: Reconstruction of the thigh extensor mechanism following wide excision of a soft-tissue sarcoma is difficult. The aim of this study was to describe the outcomes following complete quadriceps resection for large high-grade soft-tissue sarc...

  • Article
  • Open Access
6 Citations
4,179 Views
14 Pages

In his critique of religion, Hume envisages forms of religious ritual disconnected from the superstitious “neurotic” mindset; he considers simple rituals fostering moderation. In this paper, I claim that one can profitably interpret Hume&...

  • Article
  • Open Access
3,282 Views
11 Pages

7 August 2025

Background: This study aimed to evaluate the efficacy and safety of Noofen® (Phenibut) in patients with Adjustment Disorder (AjD) and to assess the usability of the ADNM-20 (Adjustment Disorder New Module 20-item questionnaire) in routine clinica...

  • Article
  • Open Access
8 Citations
4,363 Views
17 Pages

We examined the role that death anxiety (for self and others) and motivation for digital immortality played in the associations that narcissistic personality traits had with the desire for digital avatars (of self and others) in a sample of Israeli c...

  • Article
  • Open Access
3 Citations
3,413 Views
17 Pages

20 October 2024

This study aimed to examine the role of travel-related motivations and preferences for activities (such as learning about local culture, relaxation and entertainment, status and social recognition, escape and curiosity, and experience) in the relatio...

  • Article
  • Open Access
9 Citations
4,592 Views
10 Pages

Patterns of Psychiatric Outpatient Practice in Taiwan: A Nationwide Survey

  • Ying-Xiu Dai,
  • Mu-Hong Chen,
  • Tzeng-Ji Chen and
  • Ming-Hwai Lin

(1) Background: Limited studies have utilized nationwide data to assess the patterns of psychiatric practice in other countries. In this study, data from the National Health Insurance Research Database in Taiwan (NHIRD-TW) for 2012 was analyzed to de...

  • Article
  • Open Access
3 Citations
2,606 Views
10 Pages

This study analysed trends of first-time patients visiting the paediatric psychiatry clinic in a university hospital. The medical records from 2009 to 2016 of first-time patients visiting the Kyung Hee University Hospital were reviewed, focusing on c...

  • Article
  • Open Access
1,740 Views
37 Pages

29 August 2025

This study explores factors influencing micromobility (MM) use in Bursa, Turkey, focusing on personality traits, financial well-being, weather, terrain, and demographics. Using Structural Equation Modeling (SEM) with survey data from 597 respondents,...

  • Systematic Review
  • Open Access
6 Citations
6,942 Views
16 Pages

26 February 2023

The debate on personality structure and behavioral addictions is an outstanding issue. According to some authors, behavioral addictions could arise from a premorbid personality, while for others, it could result from a pathological use of technologic...

  • Article
  • Open Access
3 Citations
8,356 Views
16 Pages

18 December 2024

In certain situations, romantic engagement with a partner can have detrimental effects on an individual’s well-being and overall health, exhibiting features attributable to addictive behaviors. Considering the clinical significance of this phen...

  • Article
  • Open Access
1 Citations
3,091 Views
10 Pages

Personality Dimensions of Serbian Lifeguards

  • Goran Dimitrić,
  • Nebojša Maksimović,
  • Elena Tabakova,
  • Milorad Jakšić,
  • Dejan Orlić,
  • Selka Sadiković,
  • Dea Karaba-Jakovljević,
  • Nataša Zenić and
  • Patrik Drid

According to the World Health Organization’s (WHO) global drowning report (2017), drowning is the third leading cause of unintentional injury death worldwide. Drowning can occur anywhere there is water: oceans, seas, lakes, pools, bathtubs, riv...

  • Article
  • Open Access
27 Citations
5,123 Views
15 Pages

Psychological Effects of the COVID-19 Pandemic on Hungarian Adults

  • Csanád Szabó,
  • Judit Pukánszky and
  • Lajos Kemény

We aimed to explore psychological effects of the coronavirus pandemic on Hungarian adults in the time of the national quarantine situation in May 2020.We conducted a cross-sectional observational study with the use of an anonymous online questionnair...

  • Article
  • Open Access
9 Citations
3,302 Views
13 Pages

Maternal Competence, Maternal Burnout and Personality Traits in Italian Mothers after the First COVID-19 Lockdown

  • Concetta Polizzi,
  • Giulia Giordano,
  • Sofia Burgio,
  • Gioacchino Lavanco and
  • Marianna Alesi

This study aimed to investigate the maternal sense of competence and maternal burnout in Italian mothers during the COVID-19 pandemic. The sample was composed of 278 mothers of children/adolescents aged 4 to 17 years old. Participants were recruited...

  • Article
  • Open Access
29 Citations
4,849 Views
15 Pages

Analysis of Sociodemographic, Psychological, and Genetic Factors Contributing to Depressive symptoms in Pre-, Peri- and Postmenopausal Women

  • Elżbieta Grochans,
  • Małgorzata Szkup,
  • Artur Kotwas,
  • Jacek Kopeć,
  • Beata Karakiewicz and
  • Anna Jurczak

Depressive symptoms that are faced by women in the pre-, peri-, and postmenopausal periods are determined by a wide array of sociodemographic, psychological, and biological variables. The aim of our study was to identify factors that contribute to de...

  • Article
  • Open Access
318 Views
15 Pages

Symptoms and Diagnoses Prior to Suicide in Children and Young Adults—A Swedish Medical Record Review

  • Anna-Lena Hansson,
  • Per Johnsson,
  • Sophia Eberhard,
  • Erik Bergqvist,
  • Elin Fröding Saric,
  • Linda Karlsson,
  • Sara Lindström,
  • Margda Waern and
  • Åsa Westrin

Suicide in children and young adults is a leading cause of premature mortality, and there is a need to develop a more profound understanding of the factors that contribute to these deaths. This study is part of the nationwide Retrospective Investigat...

  • Review
  • Open Access
4 Citations
2,716 Views
18 Pages

Regenerative Peripheral Nerve Interfaces (RPNIs) in Animal Models and Their Applications: A Systematic Review

  • Jorge González-Prieto,
  • Lara Cristóbal,
  • Mario Arenillas,
  • Romano Giannetti,
  • José Daniel Muñoz Frías,
  • Eduardo Alonso Rivas,
  • Elisa Sanz Barbero,
  • Ana Gutiérrez-Pecharromán,
  • Francisco Díaz Montero and
  • Andrés A. Maldonado

17 January 2024

Regenerative Peripheral Nerve Interfaces (RPNIs) encompass neurotized muscle grafts employed for the purpose of amplifying peripheral nerve electrical signaling. The aim of this investigation was to undertake an analysis of the extant literature conc...

  • Article
  • Open Access
115 Citations
20,843 Views
12 Pages

Stress, Burnout, and Resilience among Healthcare Workers during the COVID-19 Emergency: The Role of Defense Mechanisms

  • Mariagrazia Di Giuseppe,
  • Gianni Nepa,
  • Tracy A. Prout,
  • Fabrizio Albertini,
  • Stefano Marcelli,
  • Graziella Orrù and
  • Ciro Conversano

The experience of working on the frontlines of the COVID-19 healthcare crisis has presented a cumulative traumatic experience that affects healthcare professionals’ well-being. Psychological resources such as resilience and adaptive defense mechanism...

  • Article
  • Open Access
1 Citations
2,468 Views
14 Pages

Morbidity among Adolescent Hypnotic Drug Users in Norway: An Observational Population-Based Study

  • Mohammad Nouri Sharikabad,
  • Svetlana Skurtveit,
  • Hilchen Thode Sommerschild,
  • Kristine Olsen,
  • Ingeborg Hartz,
  • Rikke Wesselhoeft,
  • Vidar Hjellvik,
  • Lars Johan Hauge and
  • Marte Handal

14 February 2024

We have previously shown that the use of hypnotic drugs increased among young Scandinavians during 2012–2018. This study aimed to explore psychiatric and somatic morbidity among adolescent hypnotic drug users in a cohort study of 13–17-ye...

  • Article
  • Open Access
3,208 Views
12 Pages

16 October 2024

Background: In the literature, female anorgasmia (AO) is closely related to obsessive–compulsive disorder (OCD), but no publication has explored the role of individual obsessive traits that may also be typical of other disorders, assuming that...

  • Article
  • Open Access
76 Citations
13,055 Views
20 Pages

2 October 2019

Behavioral finance has been widely applied in the financial realm from psychological perspectives focusing on herding and disposition effects. However, little research is devoted to the influences of personality traits on the stock investment intenti...

  • Article
  • Open Access
34 Citations
6,083 Views
12 Pages

Background: Non-suicidal self-injury (NSSI) behavior among college students is a focus of attention in current society. In the information era, the Internet serves as a public health concern and as an effective pathway for prevention. In order to red...

  • Article
  • Open Access
1 Citations
2,110 Views
14 Pages

How Were Healthcare Workers after Anti-SARS-CoV-2 Vaccination? A Study of the Emotional Side Effects of Vaccination

  • Maria Grazia Mada Logrieco,
  • Giuseppe Logrieco,
  • Ilaria Nicolì,
  • Francesca Pignatelli,
  • Francesca Lionetti,
  • Francesco Traglia,
  • Maria Spinelli,
  • Alberto Di Domenico and
  • Mirco Fasolo

Anti-SARS-CoV-2 vaccines appear to be the only escape from the COVID-19 pandemic. As healthcare workers were among the first in society to be vaccinated, understanding their emotional status post-vaccination is fundamental to the promotion of COVID-1...

  • Article
  • Open Access
4 Citations
4,334 Views
13 Pages

A Mental Health Profile of 900 Newly Arrived Refugees in Denmark Using ICD-10 Diagnoses

  • Anne Mette Fløe Hvass,
  • Lene Nyboe,
  • Kamilla Lanng,
  • Claus Vinther Nielsen and
  • Christian Wejse

31 December 2021

(1) Background: Recognizing mental health problems in newly arrived refugees poses a challenge. Little is known of the mental health profile of refugees currently arriving in Northern Europe. (2) Method: In total, we included 900 adult (≥18 years...

  • Article
  • Open Access
1 Citations
4,181 Views
9 Pages

The Influence of Personality Type on Patient Outcome Measures and Therapeutic Alliance in Patients with Low Back Pain

  • William J. Hanney,
  • Fahim Dhalla,
  • Chase Kelly,
  • Alicia Tomberlin,
  • Morey J. Kolber,
  • Abigail T. Wilson and
  • Paul A. Salamh

7 August 2023

Background: Low back pain (LBP) has been shown to have various biological, psychological, and social factors that affect prognosis. However, it is unclear how personality may influence self-reported outcome measures and therapeutic alliance (TA). Met...

  • Article
  • Open Access
3 Citations
2,211 Views
20 Pages

19 August 2024

Sanguinoderma (Ganodermataceae) is recognized as a valuable medicinal resource in Taiwan, China. Additionally, it serves as a traditional folk medicine for treating neurotic epilepsy in Malaysia. This study involved the collection of six specimens of...

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