You are currently on the new version of our website. Access the old version .

33 Results Found

  • Article
  • Open Access
28 Citations
5,287 Views
7 Pages

Isolation, Structural Elucidation of Three New Triterpenoids from the Stems and Leaves of Schisandra chinensis (Turcz) Baill.

  • Feng Qiu,
  • Han Liu,
  • Huan Duan,
  • Pian Chen,
  • Shao-Juan Lu,
  • Guang-Zhong Yang and
  • Xin-Xiang Lei

Schisandra chinensis (Turcz) Baill. is sufficiently well known as a medicinal plant worldwide, which modern research shows has many pharmacological activities such as hepatoprotective, anti-inflammatory effect, potent anti-HIV-1 activity, anti-tumor...

  • Article
  • Open Access
3 Citations
3,021 Views
17 Pages

Chemical composition is a critical factor for determining the efficacy of any traditional Chinese medicine (TCM) and can be used as an indicator of commercial quality. To develop a new strategy for discovering potential quality markers (Q-markers) of...

  • Article
  • Open Access
7 Citations
2,817 Views
15 Pages

5 September 2023

The quality of Schisandra chinensis (Turcz.) Baill. (S. chinensis) is principally attributed to lignan compounds. In this paper, a simple and rapid strategy for simultaneous extraction and determination of 10 lignans from S. chinensis was established...

  • Article
  • Open Access
29 Citations
4,745 Views
12 Pages

13 July 2021

Schisandra chinensis (Turcz.) Baill., which is known as omija in South Korea, is mainly cultivated in East Asia. The present study aimed to investigate the chemical composition of essential oil from the omija (OMEO) fruit obtained by supercritical fl...

  • Article
  • Open Access
35 Citations
5,410 Views
23 Pages

An alternating synergetic ultrasound/microwave method was applied to the simultaneous extraction of essential oils and polysaccharides with deep eutectic solvent (DES) from Schisandra chinensis. Under the optimal conditions, extract in the selected c...

  • Article
  • Open Access
5 Citations
2,709 Views
12 Pages

Study on the Rooting Physiological Mechanism of Schisandra chinensis (Turcz.) Baill. Green-Branched Cuttings

  • Dan Sun,
  • Xilin Zhao,
  • Jun Ai,
  • Zhenxing Wang,
  • Guangli Shi,
  • Yumeng Liu,
  • Xiang Li and
  • Chengcheng Zhao

3 July 2023

Schisandra chinensis (Turcz.) Baill. is an important medicinal plant in northeast China. Cutting propagation is an effective method for the rapid propagation of many tree species. This research aimed to determine a suitable growing medium and appropr...

  • Article
  • Open Access
2,328 Views
23 Pages

Phytochemical Analysis of the Extract from Berries of Schisandra chinensis Turcz. (Baill.) and Its Anti-Platelet Potential In Vitro

  • Natalia Sławińska,
  • Bogdan Kontek,
  • Jerzy Żuchowski,
  • Barbara Moniuszko-Szajwaj,
  • Jacek Białecki,
  • Kamil Zakrzewski,
  • Paulina Bogusz,
  • Anna Stochmal and
  • Beata Olas

Schisandra chinensis Turcz. (Baill.) is a dioecious vine belonging to the Schisandraceae family. Its berries show beneficial activities, including cardioprotective, antioxidant, and anti-inflammatory. We examined the chemical content of S. chinensis...

  • Review
  • Open Access
108 Citations
14,865 Views
20 Pages

Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives

  • Adriana Nowak,
  • Małgorzata Zakłos-Szyda,
  • Janusz Błasiak,
  • Agnieszka Nowak,
  • Zhuo Zhang and
  • Bolin Zhang

4 February 2019

Schisandra chinensis (Turcz.) Baill. (SCE) is a plant with high potential for beneficial health effects, confirmed by molecular studies. Its constituents exert anti-cancer effects through the induction of cell cycle arrest and apoptosis, as well as i...

  • Article
  • Open Access
3 Citations
1,536 Views
18 Pages

Magnetic Molecularly Imprinted Polymer Combined with Solid-Phase Extraction for Purification of Schisandra chinensis Lignans

  • Huijuan Xu,
  • Lihan Sun,
  • Yufei Du,
  • Wenxin Duan,
  • Wei Li,
  • Sha Luo,
  • Bing Liang,
  • Chunhui Ma and
  • Gaofeng Pan

8 November 2024

Molecularly imprinted polymers (MIPs) can specifically recognize template molecules in solution with imprinted cavities. Due to their capacity for scalable production, they can be used to isolate target products from natural products for industrial p...

  • Review
  • Open Access
25 Citations
6,612 Views
12 Pages

23 January 2023

Schisandra chinensis (S. chinensis) berries, originally a component of traditional herbal medicine in China, Korea, and other east Asian countries, are also valuable agents in modern phototherapy. S. chinensis berry preparations, including extracts a...

  • Article
  • Open Access
4 Citations
2,373 Views
15 Pages

Analysis of Lignan Content and Rhizosphere Microbial Diversity of Schisandra chinensis (Turcz.) Baill. Resources

  • Yanli Wang,
  • Yiming Yang,
  • Changyu Li,
  • Yingxue Liu,
  • Shutian Fan,
  • Yiping Yan,
  • Taiping Tian,
  • Jiaqi Li,
  • Yue Wang and
  • Peilei Xu
  • + 3 authors

28 July 2024

Genetic and environmental factors influence the growth and quality of medicinal plants. In recent years, rhizosphere microorganisms have also emerged as significant factors affecting the quality of medicinal plants. This study aimed to identify Schis...

  • Article
  • Open Access
908 Views
15 Pages

Root-Zone Temperature Drives Coordinated Photosynthesis, Root Architecture, and Metabolism Responses in Schisandra chinensis (Trucz.) Baill

  • Huimin Tang,
  • Xiaoqian Song,
  • Lu Jin,
  • Weisan Zhang,
  • Jie Zheng,
  • Lu Zhang,
  • Qiuyu Yu,
  • Yu Shi,
  • Xin Guan and
  • Zhonghua Tang
  • + 2 authors

20 August 2025

Soil warming due to climate change has a significant potential impact on crop yield and quality. Schisandra chinensis (Trucz.) Baill, a multipurpose plant disseminated in the highly climate-sensitive region of Northeast Asia, is affected by soil warm...

  • Article
  • Open Access
6 Citations
2,859 Views
16 Pages

Based on HPLC and HS-GC-IMS Techniques, the Changes in the Internal Chemical Components of Schisandra chinensis (Turcz.) Baill. Fruit at Different Harvesting Periods Were Analyzed

  • Bowei Sun,
  • Yiping Yan,
  • Mingjie Ma,
  • Jinli Wen,
  • Yanli He,
  • Yining Sun,
  • Pengqiang Yuan,
  • Peilei Xu,
  • Yiming Yang and
  • Wenpeng Lu
  • + 2 authors

22 April 2024

Schisandra chinensis, as a traditional Chinese herbal medicine, has clear pharmacological effects such as treating asthma, protecting nerves and blood vessels, and having anti-inflammatory properties. Although the Schisandra chinensis fruit contain m...

  • Feature Paper
  • Review
  • Open Access
95 Citations
14,501 Views
11 Pages

Schisandra chinensis Turcz. (Baill.) fruits, their extracts, and bioactive compounds are used in alternative medicine as adaptogens and ergogens protecting against numerous neurological, cardiovascular, gastrointestinal, liver, and skin disorders. S....

  • Review
  • Open Access
74 Citations
9,995 Views
25 Pages

Neurological diseases (NDs) are a leading cause of death worldwide and tend to mainly affect people under the age of 50. High rates of premature death and disability caused by NDs undoubtedly constrain societal development. However, effective therape...

  • Article
  • Open Access
3 Citations
3,728 Views
16 Pages

Characteristics of Schisandra chinensis (Turcz.) Baillon Collected in Habitats of South Korea

  • Beung Sung Kim,
  • Jong Soo Kim,
  • Young Jin Seo,
  • Tae Young Oh and
  • Jeong-Dong Lee

Schisandra chinensis (Turcz.) Baill. has been traditionally used as a medicine for bronchial tube ailments in Northeast Asia. Recently, the demand for S. chinensis has increased for use as food and medicine because of the lignans found in its fruits....

  • Article
  • Open Access
113 Citations
14,009 Views
18 Pages

Comparative Studies on Polyphenolic Composition, Antioxidant and Antimicrobial Activities of Schisandra chinensis Leaves and Fruits

  • Andrei Mocan,
  • Gianina Crișan,
  • Laurian Vlase,
  • Ovidiu Crișan,
  • Dan Cristian Vodnar,
  • Oana Raita,
  • Ana-Maria Gheldiu,
  • Anca Toiu,
  • Radu Oprean and
  • Ioan Tilea

22 September 2014

The aim of this paper was to evaluate the antioxidant and antimicrobial activities and the polyphenolic content of Schisandra chinensis (Turcz.) Baill. leaves and fruits. The leaves are an important source of flavonoids (35.10 ± 1.23 mg RE/g plant ma...

  • Article
  • Open Access
1 Citations
977 Views
18 Pages

Dynamic Changes in Lignan Content and Antioxidant Capacity During the Development of Three Cultivars of Schisandra chinensis Seeds

  • Zitong Zhao,
  • Manqun Liu,
  • Binhong Zhu,
  • Fan Zhang,
  • Peijin Ni,
  • Zhendong Zhang,
  • Dan Sun,
  • Zhenxing Wang,
  • Guangli Shi and
  • Jun Ai

Schisandra chinensis (Turcz.) Baill. is an important traditional medicinal plant. Lignans, the main active components of S. chinensis, have pharmacological effects, including liver protection, antioxidant, and anticancer properties. In this study, we...

  • Article
  • Open Access
3 Citations
1,969 Views
22 Pages

Optimization of Extraction of Luteolin from Schisandra chinensis by Ionic Liquid–Enzyme Complex System and Antioxidant Study Analysis

  • Jingwei Hao,
  • Nan Dong,
  • Yifan Sun,
  • Xiaoxia Lu,
  • Yingying Pei,
  • Yi Zhou,
  • Xiangkun Zhou and
  • Heming Liu

19 December 2024

The luteolin in Schisandra chinensis [Schisandraceae Schisandra (Turcz.) Baill.] were extracted by ultrasonic extraction assisted by an ionic liquid–enzyme composite system, and the content of luteolins was determined using high-performance liq...

  • Article
  • Open Access
28 Citations
6,274 Views
27 Pages

Systematically Characterize the Anti-Alzheimer’s Disease Mechanism of Lignans from S. chinensis Based on In-Vivo Ingredient Analysis and Target-Network Pharmacology Strategy by UHPLC–Q-TOF-MS

  • Mengying Wei,
  • Yuanyuan Liu,
  • Zifeng Pi,
  • Shizhe Li,
  • Mingxin Hu,
  • Yang He,
  • Kexin Yue,
  • Tianshu Liu,
  • Zhiqiang Liu and
  • Zhongying Liu
  • + 1 author

27 March 2019

Lignans from Schisandra chinensis (Turcz.) Baill can ameliorate cognitive impairment in animals with Alzheimer’s disease (AD). However, the metabolism of absorbed ingredients and the potential targets of the lignans from S. chinensis in animals...

  • Article
  • Open Access
3 Citations
2,339 Views
13 Pages

14 October 2024

Schisandra chinensis (Turcz.) Baill. (S. chinensis) and Schisandra sphenanthera Rehd. et Wils (S. sphenanthera) are called “Wuweizi” in traditional Chinese medicine, and they have distinct clinical applications. To systematically compare...

  • Article
  • Open Access
14 Citations
6,136 Views
17 Pages

21 July 2019

Schisandra chinensis (Turcz.) Baill. (S. chinensis) is a well-known botanical medicine and nutritional supplement that has been shown to have potential effects on neurodegeneration. To investigate the potential neuroprotective effect of S. chinensis...

  • Article
  • Open Access
42 Citations
8,464 Views
12 Pages

Nrf2-Mediated HO-1 Induction Contributes to Antioxidant Capacity of a Schisandrae Fructus Ethanol Extract in C2C12 Myoblasts

  • Ji Sook Kang,
  • Min Ho Han,
  • Gi-Young Kim,
  • Cheol Min Kim,
  • Byung Woo Kim,
  • Hye Jin Hwang and
  • Yung Hyun Choi

8 December 2014

This study was designed to confirm the protective effect of Schisandrae Fructus, which are the dried fruits of Schisandra chinensis (Turcz.) Baill, against oxidative stress-induced cellular damage and to elucidate the underlying mechanisms in C2C12...

  • Article
  • Open Access
705 Views
15 Pages

Rhizosphere Microbiota and Soil Nutrients Shape Fruit Lignan Composition of Schisandra chinensis Across Temperate Cultivation Sites in Northeast and Northwest China

  • Yanli Wang,
  • Wenpeng Lu,
  • Jiaqi Li,
  • Yiming Yang,
  • Shutian Fan,
  • Yue Wang,
  • Hongyan Qin,
  • Nan Shu,
  • Baoxiang Zhang and
  • Peilei Xu
  • + 4 authors

3 October 2025

Schisandra chinensis (Turcz.) Baill. (S. chinensis) is a widely used medicinal plant whose therapeutic efficacy is closely linked to its lignan content. While previous studies have focused on soil fertility and cultivar variation, the interplay among...

  • Article
  • Open Access
12 Citations
5,418 Views
16 Pages

In this study, the lactobacillus fermentation process of pomegranate (Punica granatum L.) peel and Schisandra chinensis (Turcz.) Baill (PP&SC) was optimized by using the response surface method (RSM) coupled with a Box-Behnken design. The optimum...

  • Article
  • Open Access
10 Citations
5,028 Views
11 Pages

The Anti-Inflammatory and Skin Barrier Function Recovery Effects of Schisandra chinensis in Mice with Atopic Dermatitis

  • Yoorae Son,
  • Wonjin Yang,
  • Sangjun Park,
  • Jinkyu Yang,
  • Soyeon Kim,
  • Ji-Hyo Lyu and
  • Hyungwoo Kim

24 July 2023

Background and Objectives: The fruit of Schisandra chinensis (Turcz.) Baill. is widely used medicinally to treat coughs, asthma, exhaustion, eczema, and pruritus in Northeast Asian countries, including Korea, China, and Japan. This study was designed...

  • Review
  • Open Access
21 Citations
11,725 Views
27 Pages

10 April 2024

Background: Despite some evidence supporting the synergy concept, the commonly known assumption that combinations of several herbs in one formulation can have better efficacy due to additive or synergistic effects has yet to be unambiguously and expl...

  • Review
  • Open Access
22 Citations
10,635 Views
28 Pages

A Review of the Potential Benefits of Plants Producing Berries in Skin Disorders

  • Stefano Piazza,
  • Marco Fumagalli,
  • Saba Khalilpour,
  • Giulia Martinelli,
  • Andrea Magnavacca,
  • Mario Dell’Agli and
  • Enrico Sangiovanni

During the last 30 years, berries have gained great attention as functional food against several risk factors in chronic diseases. The number of related publications on Pubmed rose from 1000 items in 1990 to more than 11,000 in 2019. Despite the fact...

  • Article
  • Open Access
13 Citations
6,268 Views
14 Pages

Determination and Comparison of Short-Chain Fatty Acids in Serum and Colon Content Samples: Alzheimer’s Disease Rat as a Case Study

  • Lin-Xiu Guo,
  • Yue Tong,
  • Jue Wang,
  • Guo Yin,
  • Hou-Shuang Huang,
  • Long Zeng,
  • Ping Wang,
  • Jun-Peng Li,
  • Kai-Shun Bi and
  • Tie-Jie Wang

4 December 2020

Short-chain fatty acids (SCFAs) are the main microbial fermentation products from dietary fibers in the colon, and it has been speculated that they play a key role in keeping healthy in the whole-body. However, differences in SCFAs concentration in t...

  • Article
  • Open Access
7 Citations
4,814 Views
12 Pages

21 July 2021

The extracts of Schisandra chinensis (Turcz.) Baill. (Schisandraceae) have various therapeutic effects, including inflammation and allergy. In this study, gomisin M2 (GM2) was isolated from S. chinensis and its beneficial effects were assessed agains...

  • Article
  • Open Access
3 Citations
2,232 Views
14 Pages

Bopyeo-tang (BPT) is composed of six medicinal herbs (Morus alba L., Rehmannia glutinosa (Gaertn.) DC., Panax ginseng C.A.Mey., Aster tataricus L.f., Astragalus propinquus Schischkin, and Schisandra chinensis (Turcz.) Baill.) and has been used for th...

  • Article
  • Open Access
9 Citations
2,946 Views
17 Pages

11 August 2023

Schizandrae Fructus (SF), fruits of Schisandra chinensis (Turcz.) Baill. and Hoveniae Semen cum Fructus (HSCF), the dried peduncle of Hovenia dulcis Thunb., have long been used for alcohol detoxification in the traditional medicine of Korea and China...

  • Review
  • Open Access
36 Citations
23,637 Views
38 Pages

18 March 2023

Plant-based nootropics are a diverse group of natural drugs that can improve cognitive abilities through various physiological mechanisms, especially in cases where these functions are weakened or impaired. In many cases, the nootropics enhance eryth...