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26 Results Found

  • Article
  • Open Access
5 Citations
3,226 Views
12 Pages

Deep Learning for the Prediction of the Survival of Midline Diffuse Glioma with an H3K27M Alteration

  • Bowen Huang,
  • Tengyun Chen,
  • Yuekang Zhang,
  • Qing Mao,
  • Yan Ju,
  • Yanhui Liu,
  • Xiang Wang,
  • Qiang Li,
  • Yinjie Lei and
  • Yanming Ren

19 October 2023

Background: The prognosis of diffuse midline glioma (DMG) patients with H3K27M (H3K27M-DMG) alterations is poor; however, a model that encourages accurate prediction of prognosis for such lesions on an individual basis remains elusive. We aimed to co...

  • Article
  • Open Access
1,083 Views
30 Pages

6 May 2025

Primary thyroid lymphoma (PTL) is a rare malignancy, and this study aimed to develop a prognostic prediction model for PTL using deep learning algorithms while providing interpretable analyses. Machine learning models were employed for mortality risk...

  • Article
  • Open Access
13 Citations
3,020 Views
11 Pages

Development of a Deep Learning Model for Malignant Small Bowel Tumors Survival: A SEER-Based Study

  • Minyue Yin,
  • Jiaxi Lin,
  • Lu Liu,
  • Jingwen Gao,
  • Wei Xu,
  • Chenyan Yu,
  • Shuting Qu,
  • Xiaolin Liu,
  • Lijuan Qian and
  • Jinzhou Zhu
  • + 1 author

Background This study aims to explore a deep learning (DL) algorithm for developing a prognostic model and perform survival analyses in SBT patients. Methods The demographic and clinical features of patients with SBTs were extracted from the Surveill...

  • Article
  • Open Access
58 Citations
7,752 Views
16 Pages

Deep Learning Predicts the Malignant-Transformation-Free Survival of Oral Potentially Malignant Disorders

  • John Adeoye,
  • Mohamad Koohi-Moghadam,
  • Anthony Wing Ip Lo,
  • Raymond King-Yin Tsang,
  • Velda Ling Yu Chow,
  • Li-Wu Zheng,
  • Siu-Wai Choi,
  • Peter Thomson and
  • Yu-Xiong Su

1 December 2021

Machine-intelligence platforms for the prediction of the probability of malignant transformation of oral potentially malignant disorders are required as adjunctive decision-making platforms in contemporary clinical practice. This study utilized time-...

  • Article
  • Open Access
1 Citations
4,223 Views
20 Pages

27 June 2025

Background/Objectives: Glioblastoma multiforme (GBM) is an aggressive and heterogeneous brain tumor with poor prognosis, emphasizing the need for reliable molecular biomarkers to improve patient stratification and treatment planning. This study aimed...

  • Article
  • Open Access
13 Citations
4,245 Views
13 Pages

Progression-Free Survival Prediction in Patients with Nasopharyngeal Carcinoma after Intensity-Modulated Radiotherapy: Machine Learning vs. Traditional Statistics

  • Ronald Wihal Oei,
  • Yingchen Lyu,
  • Lulu Ye,
  • Fangfang Kong,
  • Chengrun Du,
  • Ruiping Zhai,
  • Tingting Xu,
  • Chunying Shen,
  • Xiayun He and
  • Hongmei Ying
  • + 2 authors

12 August 2021

Background: The Cox proportional hazards (CPH) model is the most commonly used statistical method for nasopharyngeal carcinoma (NPC) prognostication. Recently, machine learning (ML) models are increasingly adopted for this purpose. However, only a fe...

  • Article
  • Open Access
147 Views
27 Pages

2 February 2026

Despite successful revascularization, patients with non-ST elevation myocardial infarction (NSTEMI) remain at higher risk of mortality and morbidity. Accurately predicting mortality risk in this cohort can improve outcomes through timely intervention...

  • Article
  • Open Access
2 Citations
1,343 Views
20 Pages

AI-Guided Chemotherapy Optimization in Lung Cancer Using Genomic and Survival Data

  • Hojin Moon,
  • Phan N. Nguyen,
  • Jaehee Park,
  • Minho Lee and
  • Sohyul Ahn

Background: Adjuvant chemotherapy (ACT) can improve survival outcomes for patients with early-stage non-small cell lung cancer (NSCLC), but its benefit varies significantly across individuals. Identifying patients who are likely to benefit from ACT r...

  • Article
  • Open Access
6 Citations
3,421 Views
13 Pages

A Study on Survival Analysis Methods Using Neural Network to Prevent Cancers

  • Chul-Young Bae,
  • Bo-Seon Kim,
  • Sun-Ha Jee,
  • Jong-Hoon Lee and
  • Ngoc-Dung Nguyen

27 September 2023

Background: Cancer is one of the main global health threats. Early personalized prediction of cancer incidence is crucial for the population at risk. This study introduces a novel cancer prediction model based on modern recurrent survival deep learni...

  • Article
  • Open Access
35 Citations
6,171 Views
15 Pages

Radiomics-Based Deep Learning Prediction of Overall Survival in Non-Small-Cell Lung Cancer Using Contrast-Enhanced Computed Tomography

  • Kuei-Yuan Hou,
  • Jyun-Ru Chen,
  • Yung-Chen Wang,
  • Ming-Huang Chiu,
  • Sen-Ping Lin,
  • Yuan-Heng Mo,
  • Shih-Chieh Peng and
  • Chia-Feng Lu

4 August 2022

Patient outcomes of non-small-cell lung cancer (NSCLC) vary because of tumor heterogeneity and treatment strategies. This study aimed to construct a deep learning model combining both radiomic and clinical features to predict the overall survival of...

  • Article
  • Open Access
6 Citations
3,120 Views
14 Pages

Risk of Mortality Prediction Involving Time-Varying Covariates for Patients with Heart Failure Using Deep Learning

  • Keijiro Nakamura,
  • Xue Zhou,
  • Naohiko Sahara,
  • Yasutake Toyoda,
  • Yoshinari Enomoto,
  • Hidehiko Hara,
  • Mahito Noro,
  • Kaoru Sugi,
  • Ming Huang and
  • Xin Zhu
  • + 2 authors

25 November 2022

Heart failure (HF) is challenging public medical and healthcare systems. This study aimed to develop and validate a novel deep learning-based prognostic model to predict the risk of all-cause mortality for patients with HF. We also compared the perfo...

  • Article
  • Open Access
4 Citations
2,515 Views
12 Pages

Survival Prediction Using Transformer-Based Categorical Feature Representation in the Treatment of Diffuse Large B-Cell Lymphoma

  • Sudarshan Pant,
  • Sae-Ryung Kang,
  • Minhee Lee,
  • Pham-Sy Phuc,
  • Hyung-Jeong Yang and
  • Deok-Hwan Yang

Diffuse large B-cell lymphoma (DLBCL) is a common and aggressive subtype of lymphoma, and accurate survival prediction is crucial for treatment decisions. This study aims to develop a robust survival prediction strategy to integrate various risk fact...

  • Article
  • Open Access
6 Citations
2,615 Views
12 Pages

Development and Validation of a Novel Score for Predicting Long-Term Mortality after an Acute Ischemic Stroke

  • Ching-Heng Lin,
  • Ya-Wen Kuo,
  • Yen-Chu Huang,
  • Meng Lee,
  • Yi-Wei Huang,
  • Chang-Fu Kuo and
  • Jiann-Der Lee

Background: Long-term mortality prediction can guide feasible discharge care plans and coordinate appropriate rehabilitation services. We aimed to develop and validate a prediction model to identify patients at risk of mortality after acute ischemic...

  • Article
  • Open Access
1 Citations
2,609 Views
15 Pages

Background: Heart failure (HF) ranks among the foremost causes of mortality globally, exhibiting particularly high prevalence and significant impact within intensive care units (ICUs). This study sought to develop, validate, and deploy a time-depende...

  • Article
  • Open Access
3 Citations
2,730 Views
12 Pages

1 December 2024

Importance: Treatment of women with stage IV breast cancer (BC) extends population-averaged survival by only a few months. Here, we develop a model for identifying individual circumstances where appropriate therapy will extend survival while minimizi...

  • Article
  • Open Access
876 Views
24 Pages

GlioSurvQNet: A DuelContextAttn DQN Framework for Brain Tumor Prognosis with Metaheuristic Optimization

  • M. Renugadevi,
  • Venkateswarlu Gonuguntla,
  • Ihssan S. Masad,
  • G. Venkat Babu and
  • K. Narasimhan

11 September 2025

Background/Objectives: Accurate classification of brain tumors and reliable prediction of patient survival are essential in neuro-oncology, guiding clinical decisions and enabling precision treatment planning. However, conventional machine learning a...

  • Article
  • Open Access
1 Citations
2,887 Views
14 Pages

Overall Survival Time Estimation for Epithelioid Peritoneal Mesothelioma Patients from Whole-Slide Images

  • Kleanthis Marios Papadopoulos,
  • Panagiotis Barmpoutis,
  • Tania Stathaki,
  • Vahan Kepenekian,
  • Peggy Dartigues,
  • Séverine Valmary-Degano,
  • Claire Illac-Vauquelin,
  • Gerlinde Avérous,
  • Anne Chevallier and
  • Nazim Benzerdjeb
  • + 6 authors

Background: The advent of Deep Learning initiated a new era in which neural networks relying solely on Whole-Slide Images can estimate the survival time of cancer patients. Remarkably, despite deep learning’s potential in this domain, no prior...

  • Article
  • Open Access
4 Citations
3,071 Views
13 Pages

18 October 2024

Background and objectives: Deep learning (DL)-based models for predicting the survival of patients with local stages of breast cancer only use time-fixed covariates, i.e., patient and cancer data at the time of diagnosis. These predictions are inhere...

  • Article
  • Open Access
38 Citations
5,049 Views
12 Pages

The Development of a Prediction Model Based on Random Survival Forest for the Postoperative Prognosis of Pancreatic Cancer: A SEER-Based Study

  • Jiaxi Lin,
  • Minyue Yin,
  • Lu Liu,
  • Jingwen Gao,
  • Chenyan Yu,
  • Xiaolin Liu,
  • Chunfang Xu and
  • Jinzhou Zhu

25 September 2022

Accurate prediction for the prognosis of patients with pancreatic cancer (PC) is a emerge task nowadays. We aimed to develop survival models for postoperative PC patients, based on a novel algorithm, random survival forest (RSF), traditional Cox regr...

  • Article
  • Open Access
5 Citations
3,387 Views
22 Pages

Enhancing Immunotherapy Response Prediction in Metastatic Lung Adenocarcinoma: Leveraging Shallow and Deep Learning with CT-Based Radiomics across Single and Multiple Tumor Sites

  • Cécile Masson-Grehaigne,
  • Mathilde Lafon,
  • Jean Palussière,
  • Laura Leroy,
  • Benjamin Bonhomme,
  • Eva Jambon,
  • Antoine Italiano,
  • Sophie Cousin and
  • Amandine Crombé

8 July 2024

This study aimed to evaluate the potential of pre-treatment CT-based radiomics features (RFs) derived from single and multiple tumor sites, and state-of-the-art machine-learning survival algorithms, in predicting progression-free survival (PFS) for p...

  • Article
  • Open Access
7 Citations
3,783 Views
21 Pages

Enhancing Survival Analysis Model Selection through XAI(t) in Healthcare

  • Francesco Berloco,
  • Pietro Maria Marvulli,
  • Vladimiro Suglia,
  • Simona Colucci,
  • Gaetano Pagano,
  • Lucia Palazzo,
  • Maria Aliani,
  • Giorgio Castellana,
  • Patrizia Guido and
  • Vitoantonio Bevilacqua
  • + 1 author

12 July 2024

Artificial intelligence algorithms have become extensively utilized in survival analysis for high-dimensional, multi-source data. However, due to their complexity, these methods often yield poorly interpretable outcomes, posing challenges in the anal...

  • Review
  • Open Access
1 Citations
7,665 Views
27 Pages

27 August 2025

The paper critically reviews face recognition models that are based on deep learning, specifically security and surveillance. Existing systems are susceptible to pose variation, occlusion, low resolution and even aging, even though they perform quite...

  • Article
  • Open Access
8 Citations
4,250 Views
19 Pages

Analysis of Real-Time Face-Verification Methods for Surveillance Applications

  • Filiberto Perez-Montes,
  • Jesus Olivares-Mercado,
  • Gabriel Sanchez-Perez,
  • Gibran Benitez-Garcia,
  • Lidia Prudente-Tixteco and
  • Osvaldo Lopez-Garcia

18 January 2023

In the last decade, face-recognition and -verification methods based on deep learning have increasingly used deeper and more complex architectures to obtain state-of-the-art (SOTA) accuracy. Hence, these architectures are limited to powerful devices...

  • Article
  • Open Access
5 Citations
3,335 Views
17 Pages

Predicting Progression of Kidney Injury Based on Elastography Ultrasound and Radiomics Signatures

  • Minyan Zhu,
  • Lumin Tang,
  • Wenqi Yang,
  • Yao Xu,
  • Xiajing Che,
  • Yin Zhou,
  • Xinghua Shao,
  • Wenyan Zhou,
  • Minfang Zhang and
  • Shan Mou
  • + 4 authors

3 November 2022

Background: Shear wave elastography ultrasound (SWE) is an emerging non-invasive candidate for assessing kidney stiffness. However, its prognostic value regarding kidney injury is unclear. Methods: A prospective cohort was created from kidney biopsy...

  • Article
  • Open Access
1 Citations
1,770 Views
19 Pages

Histology-Specific Treatment Strategies and Survival Prediction in Lung Cancer Patients with Spinal Metastases: A Nationwide Analysis

  • Abdul Karim Ghaith,
  • Xinlan Yang,
  • Taha Khalilullah,
  • Xihang Wang,
  • Melanie Alfonzo Horowitz,
  • Jawad Khalifeh,
  • A. Karim Ahmed,
  • Tej Azad,
  • Joshua Weinberg and
  • Daniel Lubelski
  • + 6 authors

21 April 2025

Background/Objectives: Spinal metastases are a common and severe complication of lung cancer, particularly in small cell lung cancer (SCLC), and are associated with poor survival. Despite advancements in treatment, optimal management strategies remai...

  • Article
  • Open Access
1,307 Views
18 Pages

Background: Endometrial cancer (EC) remains a major gynecologic malignancy with limited biomarkers for risk stratification. While killer cell lectin-like receptor G2 (KLRG2) exhibits oncogenic properties in other cancers, its clinical significance an...