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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Vaccine Design and Development

edited by

Vladimir Temchura

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4101 | Submission Open

Keywords: vaccine design; vaccine development; vaccinology; immunization; immune response; vaccine delivery; vaccine efficacy

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Novel Immunotherapies, Cell Therapies and Cancer Vaccines

edited by

Vita Golubovskaya

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3388 | Submission Open

Keywords: cell therapy; vaccine; cancer; immunotherapy; antibody

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccination Against Major Respiratory Pathogens in Livestock Farming

edited by

Enrico Brugnera

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3056 | Submission Open

Keywords: respiratory tract infections; innate and adaptive immune responses; vaccines; safety issues; risks and benefits studies

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines for Porcine Diseases

edited by Xiaohu Wang and

Lizette M. Cortes

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2506 | Submission Open

Keywords: vaccine development; immune mechanisms; adjuvants; global animal health; porcine diseases; vaccine candidate targets

(This special issue belongs to the Section Veterinary Vaccines)

Recent Research on Human Papillomavirus (HPV) Infection and Vaccination: 2nd Edition

edited by

Li Shi

and Yufeng Yao

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1844 | Submission Open

Keywords: HPV infection; HPV vaccination; willingness; hesitancy; therapeutic vaccines; cervical cancer prevention

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Chronic Viral Infections and Cancer: Openings for Vaccines and Cure

edited by

Maria G. Isaguliants

and Karl Ljungberg

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1531 | Submission Open

Keywords: chronic viral infection; oncogenic viruses; hepatitis B virus; high risk human papillomaviruses; hepatitis C virus; epstein– barr virus; human immunodeficiency virus type I; cancer associated with viral infection; immunotherapy; prophylactic viral vaccines; therapeutic viral vaccines

Immune Responses After Malaria Infection and Next Generation Malaria Vaccine

edited by Yu-Min Chuang

submission deadline 31 Jan 2026 | Viewed by 493 | Submission Open

Keywords: humoral immune response; cellular immune response; malaria; antimalaria vaccine; Plasmodium

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Reactive Vaccination During Outbreaks

edited by Giuseppe Ippolito, Gary Kobinger and Giovanni Rezza

submission deadline 31 Jan 2026 | Viewed by 383 | Submission Open

Keywords: vaccination strategies; reactive vaccination; vaccine efficacy; efficiency; duration of protection; and the selection of populations

(This special issue belongs to the Section Vaccines and Public Health)

The Era of Vaccines: Advancing Tumor Immunology and Immunotherapy

edited by

Surendra Shukla

and

Vinay Kumar

submission deadline 31 Jan 2026 | Viewed by 254 | Submission Open

Keywords: cancer immunotherapy; tumor microenvironment; immune editing; immune checkpoints; CAR-T and NK therapy; biomarkers for immunotherapy

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Communicable Diseases: New and Old Therapies and Preventive Strategies, 2nd Edition

edited by

Cristina Genovese

Calimeri Sebastiano

, Daniela Lo Giudice,

Vincenza La Fauci

and

Vincenza Gianfredi

submission deadline 26 Feb 2026 | 1 articles | Viewed by 4173 | Submission Open

Keywords: vaccines; therapies; communicable diseases

Improving HPV Vaccination Coverage: Current Issues, Future Prospects and Strategies

edited by

Irena Ilic

submission deadline 28 Feb 2026 | 8 articles | Viewed by 20773 | Submission Open

Keywords: HPV vaccine; HPV-related cancers; vaccination; vaccine coverage; vaccine acceptance; vaccine hesitancy; vaccines knowledge; attitudes and practice; immunity; prevention

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Viral Infections, Host Immunity and Vaccines

edited by Salman L. Butt and

Henry Kariithi

submission deadline 28 Feb 2026 | 6 articles | Viewed by 14753 | Submission Open

Keywords: multi-omics; innate immunity; spatial; virulence; persistence

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Recombinant Vaccine for Human and Animal Diseases

edited by

Shawn Babiuk

submission deadline 28 Feb 2026 | 3 articles | Viewed by 14093 | Submission Open

Keywords: subunit vaccines; protein expression; synthetic biology; virus like particles; bacterial antigens; baculovirus antigens; plant antigens

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines to Reduce Antimicrobial Resistance to Bacterial Pathogens

edited by

Miriam Moscoso

, Astrid Pérez and Eva Gato

submission deadline 28 Feb 2026 | 3 articles | Viewed by 11480 | Submission Open

Keywords: antimicrobial resistance; immune responses; infectious diseases; bacterial vaccines; antibody response; cellular response; mucosal immunity; efficacy evaluation; vaccine development

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Vaccines Against Flaviviruses and Alphaviruses: Recent Advances and Future Challenges—2nd Edition

edited by

Arturo Reyes-Sandoval

and

Young Chan Kim

submission deadline 28 Feb 2026 | 6 articles | Viewed by 9675 | Submission Open

Keywords: vaccine; arbovirus; flavivirus; alphavirus; vaccines; preclinical; animal model; challenge studies; clinical trials

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Safety and Side Effects in SARS-CoV-2 Vaccine

edited by

Ying-Fei Yang

and

Sher Singh

submission deadline 28 Feb 2026 | 2 articles | Viewed by 7558 | Submission Open

Keywords: COVID-19 vaccine; vaccine adverse event reporting system (VAERS); vaccine safety datalink (VSD); adverse event; safety and side effects

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

The Effectiveness of Influenza Vaccine

edited by Filippo Ansaldi and

Amicizia Daniela

submission deadline 28 Feb 2026 | 3 articles | Viewed by 7310 | Submission Open

Keywords: effectiveness; influenza vaccines; infection control; influenza vaccination; seasonal influenza vaccines

(This special issue belongs to the Section Influenza Virus Vaccines)

Enterovirus Vaccines Development and Immune Responses Following Immunization

edited by

Yuefei Jin

and

Shuaiyin Chen

submission deadline 28 Feb 2026 | 1 articles | Viewed by 7272 | Submission Open

Keywords: enterovirus; vaccine; immune efficacy; immune response

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design

edited by Tony W. Ng and Steven A. Porcelli

submission deadline 28 Feb 2026 | 2 articles | Viewed by 5091 | Submission Open

Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Vaccination and Infectious Disease Epidemics

edited by

King-Pui Florence Chan

and

Ken Ka Pang Chan

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3722 | Submission Open

Keywords: vaccination; infectious disease; epidemics; vaccination efficacy

(This special issue belongs to the Section Vaccines against Infectious Diseases)

Nanoparticle-Based Delivery Systems for Vaccines

edited by

Sergio Rosales-Mendoza

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2327 | Submission Open

Keywords: virus-like particle; nanocage; chimeric antigen; mucosal vaccine; nanoadjuvant; nanoparticle

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Receptor-Binding Domain-Based Vaccines Against SARS-CoV-2

edited by Puthupparampil Scaria

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2040 | Submission Open

Keywords: RBD vaccine; COVID-19; vaccine; SARS-CoV-2

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Advances in DNA Vaccine Research

edited by Dabbu Jaijyan

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1884 | Submission Open

Keywords: DNA vaccines; DNA-vectored vaccine; vectors for DNA vaccines; adjuvants; DNA vaccine delivery

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Vaccine Strategies to Prevent Community-Acquired Pneumonia

edited by

Vissaria Sakka

and

Garyphallia Poulakou

submission deadline 28 Feb 2026 | Viewed by 818 | Submission Open

Keywords: community-acquired respiratory infections; Streptococcus pneumoniae; Staphylococcus aureus; influenza; pneumonia; respiratory infections; respiratory pathogens

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Advancements in NK Vaccines for Solid Tumors: A Focus on Ongoing Clinical Trials

edited by

Yutao Wang

submission deadline 28 Feb 2026 | Viewed by 540 | Submission Open

Keywords: natural killer (NK) cell-based vaccines; solid tumors; cancer immunotherapy; clinical trials; immune response modulation

Mucosal Vaccines: Advances in Technology and Delivery

edited by

Kai Zhao

, Shangen Xu and Yuhong Lin

submission deadline 28 Feb 2026 | Viewed by 531 | Submission Open

Keywords: mucosal immunization; mucosal vaccine; adjuvant; vaccine delivery strategy; vaccine formulations; immune response

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Recent Advances in Ruminant Vaccines

edited by

Petr Slama

submission deadline 28 Feb 2026 | Viewed by 358 | Submission Open

Keywords: mastitis; ruminant; vaccine; mammary gland; cattle; inflammation

Memory T Cells in Vaccine-Induced Immunity for Infectious Diseases

edited by Bingdong Zhu

submission deadline 28 Feb 2026 | Viewed by 351 | Submission Open

Keywords: memory T cells; vaccination; adjuvant; immune strategy; infectious disease

Cancer Vaccines: Current Advances, Clinical Applications, and Future Directions

edited by

Paulina Niedźwiedzka-Rystwej

, Kajetan Kiełbowski and

Rafał Becht

submission deadline 28 Feb 2026 | Viewed by 292 | Submission Open

Keywords: cancer; cancer vaccines; tumor microenvironment; mRNA vaccines; DNA vaccines; neoantigen vaccines; translational medicine

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

SARS-CoV-2: Infections, Treatment, and Development of Vaccines—2nd Edition

edited by

Yasunari Matsuzaka

and

Ryu Yashiro

submission deadline 28 Feb 2026 | Viewed by 224 | Submission Open

Keywords: SARS-CoV-2; vaccines; COVID-19; diagnosis; treatment; antibodies; monoclonal antibodies; recombinant protein

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Advances in Veterinary Vaccine Development and Immunoprophylaxis for Livestock Diseases

edited by

Viviana Parreno

and

Marina Bok

submission deadline 28 Feb 2026 | Viewed by 195 | Submission Open

Keywords: livestock vaccines; veterinary immunoprophylaxis; antibody-based vaccines; nanobodies; passive immunization strategies; One Health vaccinology; sustainable animal health

(This special issue belongs to the Section Veterinary Vaccines)

Applications of Nanoparticles in Vaccines

edited by Kirsty Wilson,

Magdalena Plebanski

and Nhiem L. Tran

submission deadline 28 Feb 2026 | Viewed by 192 | Submission Open

Keywords: nanoparticles; vaccine design; nanoparticle applications in vaccines; antigen incorporation with nanoparticles; physicochemical properties of nanoparticles; adjuvant properties of nanoparticles; mechanisms of nanovaccines; immune response; disease models

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Advances in Vaccines Against Infectious Diseases

edited by

Salvatore Giovanni De Simone

submission deadline 1 Mar 2026 | 17 articles | Viewed by 50289 | Submission Open

Keywords: vaccination; antigens; disease; immune; immunity; vaccine delivery; host responses; biodefence; emerging pathogens; MERS; parasites; virus; bacteria; adjuvants

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

African Swine Fever Virus Immunotherapies and Vaccine Development

edited by

Tao Feng

and Xiaodong Qin

submission deadline 1 Mar 2026 | 1 articles | Viewed by 1492 | Submission Open

Keywords: ASFV; vaccine development; pathogenesis; immune evasion; diagnostic tools and technologies

(This special issue belongs to the Section Veterinary Vaccines)

Innovations in Vaccines for Poorly Responding Populations

edited by Martha Alexander-Miller and Kenneth E. Schmader

submission deadline 15 Mar 2026 | Viewed by 356 | Submission Open

Keywords: vaccines; infants; newborns; elderly; immunocompromised; high-risk populations; adjuvants; novel vacine platforms; correlates of protection; vaccine effectiveness

Advances in Cancer Immunotherapy and Vaccines Research: 2nd Edition

edited by

Takumi Kumai

submission deadline 20 Mar 2026 | 8 articles | Viewed by 26238 | Submission Open

Keywords: tumor vaccine; immune adjuvants; tumor immune environment; peptide vaccine; chemoradiotherapy; cytokines; suppressive immune cells; checkpoint inhibitors

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Advancements in Vaccine Research: Epidemiology, Immunogenicity, Effectiveness and Safety

edited by

Chloé Dimeglio

submission deadline 20 Mar 2026 | 6 articles | Viewed by 11840 | Submission Open

Keywords: vaccine epidemiology; immune response; immunogenicity; vaccine effectiveness; safety; infectious diseases; public health; vaccine development; immunization strategies

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Innovative Strategies to Boost the Immunogenicity of Cancer Vaccines

edited by Eric O'Neill and

Shisong Jiang

submission deadline 20 Mar 2026 | Viewed by 294 | Submission Open

Keywords: cancer vaccines; tumor antigens; tumor-associated antigens (TAAs); tumor-specific antigens (TSAs); subunit vaccines; peptide vaccines; mRNA vaccines; viral vector vaccines; adjuvants; antigen presentation; MHC class I and II upregulation; cancer immunotherapy; antibody– drug conjugates (ADCs); T cell engages; combination immunotherapy

Porcine Bacteria and Virus Vaccines

edited by Huixing Lin

submission deadline 25 Mar 2026 | Viewed by 350 | Submission Open

Keywords: Porcine; bacteria; virus; vaccine; diarrhea; dyspnea; adjuvant; attenuated vaccine; live vector vaccine; peptide vaccine

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines and Vaccine Preventable Diseases

edited by Elie Saade and Stefan Gravenstein

submission deadline 31 Mar 2026 | 8 articles | Viewed by 30214 | Submission Open

Keywords: vaccine-preventable diseases (VPDs); at-risk populations; older adults; nosocomial transmission; vaccine equity; immunization disparities; public health policy; social determinants of health; infection control; prophylactic and therapeutic vaccines

(This special issue belongs to the Section Vaccines and Public Health)

The Recent Development of Influenza Vaccine: 2nd Edition

edited by

Ramireddy Bommireddy

submission deadline 31 Mar 2026 | 8 articles | Viewed by 20382 | Submission Open

Keywords: influenza; older population; adjuvants; universal vaccine

(This special issue belongs to the Section Influenza Virus Vaccines)

Evaluating the Immune Response to RNA Vaccine

edited by

Ang Lin

and Huajun Zhao

submission deadline 31 Mar 2026 | 5 articles | Viewed by 16060 | Submission Open

Keywords: RNA vaccine; mechanism of action; immune regulation; innate immunity; adaptive vaccine response

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Viral Vector-Based Vaccines and Therapeutics

edited by Sujit Pujhari

submission deadline 31 Mar 2026 | 7 articles | Viewed by 13732 | Submission Open

Keywords: viral vectors; vaccine technology; gene therapy; immunization strategies; vector design; vaccine safety; vector-based therapeutics

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Animal Diseases: Immune Response and Vaccines

edited by

Verónica Martín

, José M. Rojas and

Noemí Sevilla

submission deadline 31 Mar 2026 | 8 articles | Viewed by 11669 | Submission Open

Keywords: immune responses; ruminants; vaccines; animal health

(This special issue belongs to the Section Veterinary Vaccines)

The Role of Vaccination on Public Health and Epidemiology

edited by

Antonio Rosa de Sousa Neto

and Daniela Reis Joaquim de Freitas

submission deadline 31 Mar 2026 | 4 articles | Viewed by 11110 | Submission Open

Keywords: vaccines; immunization; epidemiology; public health; vaccine-preventable diseases; pandemic preparedness; health equity

(This special issue belongs to the Section Vaccines and Public Health)

Herpes Simplex Virus Infection, Immunity, and Vaccine Development

edited by

Lbachir BenMohamed

and Swayam Prakash

submission deadline 31 Mar 2026 | 1 articles | Viewed by 7476 | Submission Open

Keywords: Herpes Simplex Virus (HSV); protection; humoral; and cellular immune mechanisms; vaccine development; HSV-1; HSV-2; immunization strategies

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Cancer Vaccines: 4th Edition

edited by

So Young Yoo

submission deadline 31 Mar 2026 | 2 articles | Viewed by 6848 | Submission Open

Keywords: cancer immunotherapy; therapeutic vaccine; tumor-associated antigens; neoantigens; adjuvant; tumor microenvironment; oncolytic viruses; immune checkpoint inhibitors

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Hepatitis Vaccines: Safety, Efficacy and Global Impact

edited by

Muhammad Atif Zahoor

submission deadline 31 Mar 2026 | 2 articles | Viewed by 6292 | Submission Open

Keywords: viral hepatitis; prevention of viral hepatitis through effective vaccines; safety and efficacy of hepatitis vaccines; immunogenicity of hepatitis vaccines; vaccine innovation; global prevention strategies; global health impact; vaccine failures and future challenges

(This special issue belongs to the Section Hepatitis Virus Vaccines)

From Knowledge to Action: Advances in Herpes Zoster Vaccine and Vaccination

edited by Giulia Silvestrini and

Manuela Chiavarini

submission deadline 31 Mar 2026 | 2 articles | Viewed by 5601 | Submission Open

Keywords: knowledge; attitudes; and practices regarding herpes zoster vaccination; vaccine hesitancy; vaccine uptake and inequality; efficacy; reactogenicity; and safety of herpes zoster vaccine; efficacy of different vaccines; the role of different type of herpes zoster vaccine in different target of population; active campaign

(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

Novel Adjuvants and Delivery Systems for Vaccines

edited by Christiane Chbib and

Mohammad N. Uddin

submission deadline 31 Mar 2026 | 2 articles | Viewed by 4209 | Submission Open

Keywords: vaccines; drug development; adjuvants; nanoparticle

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

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