Cancer Vaccines: Current Advances, Clinical Applications, and Future Directions
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Cancer Vaccines and Immunotherapy".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 107
Special Issue Editors
2. Center for Experimental Immunology and Immunobiology in Infectious Diseases and Cancer, University of Szczecin, Szczecin, Poland
Interests: animal models; viral infections; immune system; innate immunity; T cells; flow cytometry; real-time PCR
Special Issues, Collections and Topics in MDPI journals
Interests: oncology; translational medicine; inflammation; cancer vaccines; cancer immunotherapy; targeted therapy; clinical trials
Special Issue Information
Dear Colleagues,
Immunotherapy has become a pillar in the systemic treatment of malignancies. The introduction of immune checkpoint inhibitors and CAR T cells changed how we perceive prognosis in several oncological diseases. Anticancer vaccines represent another approach to tumor immunotherapy. Preventive vaccines, such as anti-HPV or -HBV, proved their efficacy in reducing the risk of cancer development. However, therapeutic vaccines aim to reshape one’s immunological profile to increase cytotoxic and anticancer properties to treat an already present tumor. Introducing mRNA, DNA, neoantigens, or stimulated dendritic cells promotes the presentation of cancer antigens, thus enhancing CD8+ T cell-mediated anticancer effects. Implementing anticancer therapeutic vaccines should broaden the treatment potential in cancers with difficulties in developing targeted therapies. Furthermore, it could improve the anticancer activity of other oncological therapeutics or reduce treatment resistance.
This Special Issue aims to present original research papers and reviews that provide updates and discuss novel opportunities for anticancer therapeutic vaccines. Manuscripts and reviews in the following research areas are encouraged: nucleic acid vaccines, cellular vaccines, viral vaccines, preclinical and clinical studies, and translational medicine.
We look forward to receiving your contributions.
Dr. Paulina Niedźwiedzka-Rystwej
Dr. Kajetan Kiełbowski
Dr. Rafał Becht
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer
- cancer vaccines
- tumor microenvironment
- mRNA vaccines
- DNA vaccines
- neoantigen vaccines
- translational medicine
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