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Vaccines
Special Issues
Vaccination and Infectious Disease Epidemics
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Vaccination and Infectious Disease Epidemics

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccines against Infectious Diseases".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 835

Special Issue Editors

Dr. King-Pui Florence Chan

E-Mail Website
Guest Editor
Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Interests: respiratory; infection disease; epidemiology
Dr. Ken Ka Pang Chan

E-Mail Website
Guest Editor
1. Department of Medicine & Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
2. Li Ka Shing Institute of Health Sciences, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China
Interests: pleural diseases; interventional pulmonology; respiratory infection

Special Issue Information

Dear Colleagues,

Vaccination is an important health intervention, helping to prevent individuals from contracting specific infectious diseases before they come into contact with them. It is a simple, safe, and effective preventive measure that reduces complications. The World Health Organization recommends routine immunization. The mortality and morbidity associated with outbreaks of infectious diseases, such as the COVID-19 pandemic, have significantly transformed both clinical and public perceptions of vaccination. Changes in vaccine uptake, real-world effectiveness, and new evidence regarding vaccination during infectious disease epidemics necessitate a reconsideration of our current understanding of vaccination as a means of disease prevention.

This Special Issue on “Vaccination and Infectious Disease Epidemics” aims to garner original articles, reviews, and reports that provide novel insights and real-world data on the use of vaccinations against infectious diseases. We look forward to receiving your contributions.

Dr. King-Pui Florence Chan
Dr. Ken Ka Pang Chan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vaccination
  • infectious disease
  • epidemics
  • vaccination efficacy

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Published Papers (1 paper)

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Research

20 pages, 4021 KB  
Article
Mumps Epidemiology in the Autonomous Province of Vojvodina, Serbia: Long-Term Trends, Immunization Gaps, and Conditions Favoring Future Outbreaks
by Mioljub Ristić, Vladimir Vuković, Smiljana Rajčević, Marko Koprivica, Nikica Agbaba and Vladimir Petrović
Vaccines 2025, 13(8), 839; https://doi.org/10.3390/vaccines13080839 - 6 Aug 2025
Viewed by 639
Abstract
Background/Objectives: Mumps remains a relevant vaccine-preventable disease globally, especially in settings where immunization coverage fluctuates or vaccine-induced immunity wanes. This study aimed to assess long-term trends in mumps incidence, vaccination coverage, clinical outcomes, and demographic characteristics in the Autonomous Province of Vojvodina [...] Read more.
Background/Objectives: Mumps remains a relevant vaccine-preventable disease globally, especially in settings where immunization coverage fluctuates or vaccine-induced immunity wanes. This study aimed to assess long-term trends in mumps incidence, vaccination coverage, clinical outcomes, and demographic characteristics in the Autonomous Province of Vojvodina (AP Vojvodina), Serbia, over a 47-year period. Methods: We conducted a retrospective observational study using surveillance data from the Institute of Public Health of Vojvodina. Analyses included annual mumps incidence rates (1978–2024), coverage with mumps-containing vaccines (MuCVs; 1986–2024), monthly case counts, and individual-level case data for the 1997–2024 period. Variables analyzed included age, month of notification, gender, vaccination status, presence of clinical complications, and the method used for case confirmation. Results: Following the introduction of MuCV in 1986, the mumps incidence markedly declined, with limited resurgences in 2000, 2009, and 2012. Between 1997 and 2024, a total of 1358 cases were reported, with 62.7% occurring in males. Over time, the age distribution shifted, with adolescents and young adults being increasingly affected during the later (2011–2024) observed period. In 2012, the highest age-specific incidence was observed among individuals aged 10–19 and 20–39 years (49.1 and 45.5 per 100,000, respectively). Vaccination coverage for both MuCV doses was suboptimal in several years. The proportion of unvaccinated cases decreased over time, while the proportion with unknown vaccination status increased. Mumps-related complications—such as orchitis, pancreatitis, and meningitis—were rare and predominantly affected unvaccinated individuals: 84.2% of orchitis, 40.0% of pancreatitis, and all meningitis cases. Only two pancreatitis cases (40.0%) were reported after one MMR dose, while fully vaccinated individuals (two doses) had one orchitis case (5.3%) and no other complications. Laboratory confirmation was applied more consistently from 2009 onward, with 49.6% of cases confirmed that year (58 out of 117), and, in several years after 2020, only laboratory-confirmed cases were reported, indicating improved diagnostic capacity. Conclusions: Despite substantial progress in controlling mumps, gaps in vaccine coverage, waning immunity, and incomplete vaccination records continue to pose a risk for mumps transmission. Strengthening routine immunization, ensuring high two-dose MuCV coverage, improving vaccination record keeping, and enhancing laboratory-based case confirmation are critical. Consideration should be given to booster doses in high-risk populations and to conducting a seroepidemiological study to estimate the susceptible population for mumps in AP Vojvodina. Full article
(This article belongs to the Special Issue Vaccination and Infectious Disease Epidemics)
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