The Role of Vaccination on Public Health and Epidemiology

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccines and Public Health".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 1285

Special Issue Editors


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Guest Editor
Nursing Department, Federal University of Piaui, Teresina 64049-550, Brazil
Interests: microbiology; parasitology; prevention and control of infections in healthcare services; health education; biosafety; public health; health surveillance and care; bibliometric analysis and scientific production in health

E-Mail Website
Guest Editor
Nursing Department, Federal University of Piaui, Teresina 64049-550, Brazil
Interests: microbiology applied to infection prevention and control in health services; microorganisms and infectious diseases: viruses, bacteria, parasites; host–parasite relationship; infection control mechanisms; bacterial and parasitic resistance
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Special Issue Information

Dear Colleagues,

Vaccination remains one of the most effective public health interventions, preventing millions of deaths annually and reducing the burden of infectious diseases worldwide. Immunization programs have played a crucial role in shaping public health, enhancing epidemiological surveillance, and mitigating health crises. However, challenges such as vaccine hesitancy, equitable distribution, and the emergence of new pathogens require continuous research and innovation.

This Special Issue seeks to compile innovative research and critical discussions on the impact of vaccination strategies across diverse populations and health systems. We invite original research articles and reviews on a wide range of topics that may include topics on the following:

Effectiveness and Impact of Vaccination:

  • Evaluation of global or regional immunization; epidemiology; long-term immunity and strategies for booster vaccinations.

Vaccine-Preventable Diseases and Epidemiological Trends:

  • Aspects of surveillance of vaccine-preventable diseases; emerging and re-emerging infectious threats.

Features Associated with Vaccination and Hesitancy:

  • Social determinants, information, and vaccine attributes that may affect vaccination.

Technological Advances in Vaccination:

  • Innovations in development and delivery; advances in immunization for high-risk populations.

Dr. Antonio Rosa de Sousa Neto
Dr. Daniela Reis Joaquim Reis Joaquim de Freitas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vaccines
  • immunization
  • epidemiology
  • public health
  • vaccine-preventable diseases
  • pandemic preparedness
  • health equity

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Published Papers (1 paper)

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15 pages, 1789 KiB  
Systematic Review
Efficacy, Immunogenicity, and Safety of Pertussis Vaccine During Pregnancy: A Meta-Analysis
by Qianqian Shi, Jun Li, Quanman Hu, Cheng Cheng, Kun Yang, Xiaoyu Li, Xiaoru Song, Shuaiyin Chen and Guangcai Duan
Vaccines 2025, 13(7), 666; https://doi.org/10.3390/vaccines13070666 - 20 Jun 2025
Viewed by 945
Abstract
Background: A growing number of countries implement prenatal pertussis vaccination policies to safeguard unvaccinated infants. This meta-analysis aimed to evaluate the efficacy, immunogenicity, and safety of antenatal Tdap vaccination in pregnant individuals. Methods: We systematically searched PubMed, Embase, and Web of Science from [...] Read more.
Background: A growing number of countries implement prenatal pertussis vaccination policies to safeguard unvaccinated infants. This meta-analysis aimed to evaluate the efficacy, immunogenicity, and safety of antenatal Tdap vaccination in pregnant individuals. Methods: We systematically searched PubMed, Embase, and Web of Science from their inception to 16 February 2025, rigorously screening studies and including seven randomized controlled trials and 10 case-control studies published between 2014 and 2024. For the test-negative design meta-analysis, odds ratios with 95% confidence intervals served as effect estimates, and vaccine efficacy was calculated accordingly. Standardized mean differences were used to assess geometric mean concentrations, while relative risks evaluated safety. Results: Maternal vaccination during pregnancy demonstrated 85% vaccine effectiveness (95% CI: 78–89%) in protecting infants under 3 months old. Pooled standardized mean differences for cord blood IgG antibodies against pertussis toxin, pertactin, and filamentous hemagglutinin were 1.57 (95% CI: 1.25–1.89), 2.15 (95% CI: 1.82–2.48), and 2.25 (95% CI: 1.81–2.68), respectively, indicating higher antibody levels in infants of vaccinated women before their first immunization. Safety analysis showed no significant association between Tdap vaccination during pregnancy and serious adverse events in infants (RR = 0.76, 95% CI: 0.46–1.24) and pregnant women (RR = 1.22, 95% CI: 0.83–1.81). Conclusion: Our findings support the implementation of pertussis vaccination during pregnancy. Full article
(This article belongs to the Special Issue The Role of Vaccination on Public Health and Epidemiology)
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