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Insight into Infectious Disease Epidemiology and Public Health

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Infectious Diseases".

Deadline for manuscript submissions: 25 October 2026 | Viewed by 1372

Special Issue Editors


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Guest Editor
Department of Infectious Disease and Public Health, Sapienza University of Rome, 00185 Rome, Italy
Interests: gender medicine; health management; public health

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Guest Editor
Internal Medicine Unit, Castelli Hospital, ASL Roma 6, Rome, Italy
Interests: internal medicine; acute complex patients management; emergencies

Special Issue Information

Dear Colleagues,

The recent outbreak of SARS-CoV-2 has, on the one hand, put infectious diseases (especially non-pediatric ones) back in the spotlight and, on the other, highlighted how they now form part of a world marked by non-communicable diseases: it is no coincidence that there has been talk of a syndemic. This entails a double impact, both clinical and healthcare-related, in terms of public health. In an increasingly clinically focused world, where combining health, healthcare, and clinical outcomes has become essential, the allocation of resources is fundamental. At the same time, we can no longer ignore the influence of gender in the therapeutic pathway, both as a positive and negative prognostic factor.

For this reason, I encourage you to send us your studies on infectious diseases and public health, especially if they include a stratification of patients by sex and age, combining the clinical aspect with an assessment of healthcare impact, even if only in summary form or at least as a projection/forecast.

Dr. Francesco Rosiello
Dr. Filomena Pietrantonio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gender medicine
  • health management
  • public health
  • infectious disease, sindemics

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Published Papers (1 paper)

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Research

16 pages, 482 KB  
Article
Respiratory and Related Comorbidities’ Role in the Risk of Acute Sinusitis: A 15-Year Longitudinal Clinical Study
by Omar Abdel-Fattah Ahmed, Amr Sayed Ghanem, Marianna Móré and Attila Csaba Nagy
J. Clin. Med. 2026, 15(2), 660; https://doi.org/10.3390/jcm15020660 - 14 Jan 2026
Cited by 2 | Viewed by 1038
Abstract
Background/Objectives: Acute sinusitis (AS) is a common infection of the upper respiratory tract that places considerable clinical and economic burden worldwide. Although frequently encountered in practice, the factors that predispose individuals to AS remain poorly understood. This study examined how different respiratory [...] Read more.
Background/Objectives: Acute sinusitis (AS) is a common infection of the upper respiratory tract that places considerable clinical and economic burden worldwide. Although frequently encountered in practice, the factors that predispose individuals to AS remain poorly understood. This study examined how different respiratory disorders and comorbidities influence the likelihood of developing AS, aiming to clarify its underlying risk profile. Methods: A longitudinal analysis was performed using electronic health records from the Clinical Center of the University of Debrecen Hospital. The study cohort (2007–2022) encompassed 37,164 observations. To evaluate the risk of AS progression, Log-Rank tests and Cox proportional hazards regressions were applied whilst adjusting for covariates. Results: The risk of developing AS was significantly higher among individuals with preceding respiratory conditions. Patients with common cold demonstrated a 2.3-fold increased risk of developing AS (95% CI [1.51–3.40]). Compared to those without such disorders, participants with acute bronchitis had a 2.5-fold higher hazard of AS (95% CI 1.90–3.26). The strongest association was observed for allergic rhinitis (HR = 4.04, 95% CI 3.18–5.13), followed by chronic sinusitis (HR = 3.10, 95% CI 2.13–4.51). Chronic obstructive pulmonary disease was also identified as a significant predictor for AS (HR = 1.62, 95% CI 1.04–2.52), whereas dental pathologies were associated with a modest protective effect (HR = 0.69, 95% CI 0.48–0.97). Conclusions: Patients with allergic rhinitis, chronic sinusitis, acute bronchitis, common cold, or chronic obstructive pulmonary disease have a markedly higher risk of developing AS. Clinicians should actively screen for these conditions when assessing patients with recurrent or severe sinus infections. Early recognition and management of underlying respiratory disorders may reduce AS episodes, promote symptom control, and lessen healthcare burdens. Future research should concentrate on precision medicine to leverage AS preventive and management strategies. Full article
(This article belongs to the Special Issue Insight into Infectious Disease Epidemiology and Public Health)
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