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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Practice of Imaging in Coronary Interventional Therapy

edited by Nobuaki Suzuki

submission deadline 10 Sep 2026 | Viewed by 248 | Submission Open

Keywords: coronary artery disease; cardiac imaging; intravascular ultrasound; near-infrared spectroscopy; optical coherence tomography; fractional flow reserve computed tomography

(This special issue belongs to the Section Cardiology)

Cardiac Amyloidosis and Amyloid Cardiomyopathy: Advances in Cardiovascular Care

edited by Marcus Anthony Urey

submission deadline 10 Sep 2026 | Viewed by 218 | Submission Open

Keywords: amyloidosis; diagnostics; disease progression; restrictive cardiomyopathy; degraders; silencers; stabilizers

(This special issue belongs to the Section Cardiology)

Recent Advances in Lymphedema

edited by Shinsuke Akita

submission deadline 10 Sep 2026 | Viewed by 215 | Submission Open

Keywords: lymphedema; lymphaticovenular anastomosis (LVA); vascularized lymph node transfer (VLNT); immediate lymphatic reconstruction; indocyanine green lymphography; ultrasonography; bioimpedance analysis; imaging and staging of lymphedema; fibrosis and inflammation; patient-reported outcome measures

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Gynecologic Robotic Surgery: Evolution, Current Status and Future Directions

edited by Youn-Jee Chung

submission deadline 13 Sep 2026 | 2 articles | Viewed by 1427 | Submission Open

Keywords: laparoscopy; robot surgery; minimally invasive surgery; gynecology; endometriosis; myoma; adenomyosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Musculoskeletal Spine Disorders: Clinical Management, Rehabilitation Strategies, and Technological Innovations

edited by

Maria Chiara Maccarone

Nicola Manocchio

and Calogero Foti

submission deadline 14 Sep 2026 | 2 articles | Viewed by 1240 | Submission Open

Keywords: spine disorders; rehabilitation; physical exercise; low back pain; scoliosis; adolescent idiopathic scoliosis

(This special issue belongs to the Section Orthopedics)

Biomarkers and Diagnostics in Neurological Diseases

edited by Maria Ioanna Stefanou

submission deadline 15 Sep 2026 | 10 articles | Viewed by 19864 | Submission Open

Keywords: biomarkers; neurological diseases; diagnosis; lipoprotein(a); neurofilament protein; tau peptide; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

Advances in Diagnosis and Treatment of Endometriosis

edited by

Arrigo Fruscalzo

and

Anis Feki

submission deadline 15 Sep 2026 | 6 articles | Viewed by 11118 | Submission Open

Keywords: endometriosis; adenomyosis; diagnosis; classification; therapy; progesterone

(This special issue belongs to the Section Obstetrics & Gynecology)

Thyroid Disease: Updates from Diagnosis to Treatment: 2nd Edition

edited by

Luca Giovanella

and

Petra Petranović Ovčariček

submission deadline 15 Sep 2026 | 7 articles | Viewed by 9272 | Submission Open

Keywords: autoimmune thyroid diseases; thyroiditis; thyroid cancers; PET/CT; hyperthyroidism

(This special issue belongs to the Section Endocrinology & Metabolism)

Current Challenges in Clinical Dentistry: 3rd Edition

edited by

Eiji Tanaka

and

Susumu Abe

submission deadline 15 Sep 2026 | 2 articles | Viewed by 4698 | Submission Open

Keywords: artificial intelligence; clinical dentistry; cutting-edge device and technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Plastic and Reconstructive Surgery: Clinical Advances and Future Opportunities

edited by Rami S Kantar

submission deadline 15 Sep 2026 | 5 articles | Viewed by 4295 | Submission Open

Keywords: plastic surgery; reconstructive surgery; cleft lips; palates; post-traumatic reconstruction; facial transplantation; craniofacial surgery; cleft surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Latest Advances in Thoracic Surgery: 2nd Edition

edited by

Hideki Ujiie

submission deadline 15 Sep 2026 | 2 articles | Viewed by 4042 | Submission Open

Keywords: lung cancer; surgical oncology; robotic surgery; thoracic surgery; lung diseases; minimally invasive surgery

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Obesity and Bariatric Surgery—2nd Edition

edited by Valentin Mocanu and Jerry Dang

submission deadline 15 Sep 2026 | 3 articles | Viewed by 3060 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; anti-obesity medications; obesity treatment

(This special issue belongs to the Section Endocrinology & Metabolism)

Risk Prediction in Mechanical Circulatory Support (MCS) and Cardiac Transplantation

edited by

Nandini Nair

submission deadline 15 Sep 2026 | 3 articles | Viewed by 3028 | Submission Open

Keywords: advanced heart failure; mechanical circulatory support (MCS); cardiac transplantation; heart transplantation; risk prediction

(This special issue belongs to the Section Cardiology)

Clinical Management and Challenges of Sepsis and Septic Shock

edited by

Matteo Guarino

and

Michele Domenico Spampinato

submission deadline 15 Sep 2026 | 2 articles | Viewed by 1583 | Submission Open

Keywords: sepsis; septic shock; hemodynamic management; biomarkers; cardiovascular dysfunction; point-of-care ultrasound; precision medicine; emergency medicine; critical care

(This special issue belongs to the Section Intensive Care)

Advances in Pancreatic Cancer: Diagnosis and Therapy

edited by Eleonora Lai,

Nicola Silvestris

and

Mario Scartozzi

submission deadline 15 Sep 2026 | 1 articles | Viewed by 1243 | Submission Open

Keywords: pancreatic cancer diagnosis; endoscopic ultrasound; neoadjuvant chemotherapy; surgical resection; targeted therapy; immunotherapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Sports Injuries: Emerging Trends in Risk Mitigation, Management and Recovery

edited by

Luis Suárez-Arrones

and Jose Asian-Clemente

submission deadline 15 Sep 2026 | 3 articles | Viewed by 1132 | Submission Open

Keywords: injury prevention; rehabilitation; muscle; return-to-sport; surgery; therapy; testing; regenerative medicine; ultrasound; MRI; sports medicine

(This special issue belongs to the Section Sports Medicine)

Advances in Cardiac Resynchronization Treatment: 2nd Edition

edited by

George Leventopoulos

, Konstantinos A. Gatzoulis, Konstantinos Aronis and

Dimitris L. Tsiachris

submission deadline 15 Sep 2026 | 1 articles | Viewed by 940 | Submission Open

Keywords: conduction system; risk stratification; resynchronization; cardiac pacing; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Cancers: Clinical Radiation Therapy

edited by Julianne M. Pollard-Larkin

submission deadline 15 Sep 2026 | 1 articles | Viewed by 939 | Submission Open

Keywords: reirradiation; tissue tolerance; image registration; treatment planning; dose accumulation

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Esophageal and Upper Gastrointestinal Surgery: Clinical Advances and Practical Updates

edited by

Pedro Serralheiro

and Peter Grimminger

submission deadline 15 Sep 2026 | 1 articles | Viewed by 907 | Submission Open

Keywords: esophageal cancer; gastric cancer; upper GI surgery; surgical oncology; benign upper GI surgery; surgical innovation; surgical outcomes; surgical guidelines; robotic surgery; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cardiovascular Disease in MASLD: New Advances in Therapeutic Targets

edited by

Alfredo Caturano

submission deadline 15 Sep 2026 | 1 articles | Viewed by 876 | Submission Open

Keywords: MASLD; cardiovascular disease (CVD); metabolic dysfunction; steatotic liver disease; insulin resistance; dyslipidemia; atherosclerosis; inflammation; GLP-1 receptor agonists; SGLT2 inhibitors; lipid-lowering therapies; cardiometabolic risk; clinical trials; therapeutic targets

(This special issue belongs to the Section Cardiovascular Medicine)

Cardiac Arrest: Appropriate Prognostication and Therapeutic Options

edited by

Jae Hoon Lee

and Jin-hong Min

submission deadline 15 Sep 2026 | 1 articles | Viewed by 744 | Submission Open

Keywords: cardiac arrest; prognosis; hypothermia, induced; resuscitation; magnetic resonance imaging; electroencephalog-raphy; blood pressure; hypoxia-ischemia, brain; extracorporeal membrane oxygenation

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Endoscopic Techniques for Gastrointestinal Diseases

edited by Alberto Tringali

submission deadline 15 Sep 2026 | 1 articles | Viewed by 559 | Submission Open

Keywords: hepatobiliary disease; pancreatic disease; ERCP; interventional EUS; cholangiopancreatoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Pulmonary Arterial Hypertension: Emerging Therapies and Clinical Outcomes

edited by Namita Sood

submission deadline 15 Sep 2026 | Viewed by 367 | Submission Open

Keywords: pulmonary arterial hypertension (PAH); PAH therapy; emerging treatments; sotatercept; inhaled therapy; targeted pharmacotherapy; combination therapy; therapeutic efficacy; pulmonary vascular imaging

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Endodontics

edited by

Vincenzo Tosco

submission deadline 15 Sep 2026 | Viewed by 342 | Submission Open

Keywords: endodontics; vital pulp therapy; minimally invasive endodontics; clinical endodontic techniques; bioactive sealers

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

State of the Art of Lung Surgery: Modern Horizons in Lung Cancer Treatment

edited by

Alessio Mariolo

and Edouard Sage

submission deadline 15 Sep 2026 | Viewed by 316 | Submission Open

Keywords: lung-cancer-surgery; thoracic oncology; RATS; VATS; induction therapy; neoadjuvant-immunotherapy; non-intubated thoracic surgery; NITS; segmentectomy; lung-sparing surgery; 3D-reconstruction

(This special issue belongs to the Section General Surgery)

Recent Clinical Updates on Vascular and Endovascular Surgery

edited by

Mª Lourdes Del Río-Solá

and

Sergi Bellmunt-Montoya

submission deadline 15 Sep 2026 | Viewed by 306 | Submission Open

Keywords: vascular surgery; endovascular surgery; aortic disease; abdominal aortic aneurysm; peripheral arterial disease; chronic venous disease; endovascular repair; open vascular surgery

(This special issue belongs to the Section Vascular Medicine)

Innovations and Advancements in Spine Surgery

edited by Mitchell K. Ng

submission deadline 15 Sep 2026 | Viewed by 286 | Submission Open

Keywords: spine surgery; minimally invasive spine surgery; robotic-assisted spine surgery; spinal navigation; endoscopic spine surgery; spinal implant; biologics and regenerative therapies; perioperative optimization; patient-reported outcomes; value-based spine care; surgical innovation

(This special issue belongs to the Section Orthopedics)

Cardiac Imaging in the Clinical Management of Heart Failure

edited by Maria Concetta Pastore

submission deadline 15 Sep 2026 | Viewed by 274 | Submission Open

Keywords: heart failure; cardiac imaging; echocardiography; cardiac magnetic resonance; computed tomography; nuclear imaging

(This special issue belongs to the Section Cardiology)

New Insights into Acute Care and Emergency Surgery: 2nd Edition

edited by Jacob Chen and Avi Benov

submission deadline 15 Sep 2026 | Viewed by 255 | Submission Open

Keywords: trauma surgery; emergency surgery; acute care; anesthesia; ICU

(This special issue belongs to the Section General Surgery)

Innovations in Advanced Heart Failure Detection and Management

edited by Vinh Q. Chau and Nikhil Narang

submission deadline 15 Sep 2026 | Viewed by 231 | Submission Open

Keywords: advanced heart failure; systolic heart failure; mechanical circulatory support; left ventricular assist device; heart transplantation outcomes

(This special issue belongs to the Section Cardiology)

Application of Physiotherapy in Clinical Rehabilitation

edited by

Kyeongbong Lee

submission deadline 17 Sep 2026 | 1 articles | Viewed by 862 | Submission Open

Keywords: therapeutic exercise; neurological rehabilitation; musculoskeletal physiotherapy; cardiopulmonary rehabilitation; intensive care unit (ICU) rehabilitation; gait and balance; pediatric and geriatric physical therapy; sports physical therapy; rehabilitation technology

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Advances in Kidney Transplantation

edited by

Florin Ioan Elec

and

Oana Antal

submission deadline 18 Sep 2026 | 6 articles | Viewed by 8682 | Submission Open

Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Clinical Perspectives in Pediatric Surgery: From Neonatal Procedures to Adolescent Care

edited by

Mirko Bertozzi

and

Giovanna Riccipetitoni

submission deadline 18 Sep 2026 | 1 articles | Viewed by 821 | Submission Open

Keywords: mini invasive surgery; transitional care of rare diseases; newborn surgery; long-term follow up; congenital malformations

(This special issue belongs to the Section Clinical Pediatrics)

Current Trends in Implant Dentistry

edited by Marco Toia

submission deadline 20 Sep 2026 | 9 articles | Viewed by 29516 | Submission Open

Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advancements in Spine Surgery: Best Practices and Outcomes

edited by

Mitsuru Yagi

submission deadline 20 Sep 2026 | 12 articles | Viewed by 26121 | Submission Open

Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis

(This special issue belongs to the Section Orthopedics)

Applied Cardiorespiratory Physiology in Critical Care Medicine

edited by

Athanasios Chalkias

and Paraskevi Tselioti

submission deadline 20 Sep 2026 | 5 articles | Viewed by 19383 | Submission Open

Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology

(This special issue belongs to the Section Anesthesiology)

Acute Pancreatitis and Its Complications: Current Diagnostics and Management

edited by

Beata Jabłońska

submission deadline 20 Sep 2026 | 5 articles | Viewed by 19361 | Submission Open

Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Skin Disease and Inflammation

edited by

Taihao Quan

submission deadline 20 Sep 2026 | 4 articles | Viewed by 16428 | Submission Open

Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea

(This special issue belongs to the Section Dermatology)

Coronary Artery Disease: Diagnosis, Treatment Challenges, and Emerging Therapy

edited by

Athanasios Samaras

and

Andreas S. Papazoglou

submission deadline 20 Sep 2026 | 5 articles | Viewed by 12325 | Submission Open

Keywords: coronary artery disease; percutaneous coronary intervention; cardiovascular disease; emerging therapies; treatment challenges; biomarkers; interventional cardiology

(This special issue belongs to the Section Cardiology)

Clinical Advances in Musculoskeletal Disorders: 2nd Edition

edited by

Peter V. Giannoudis

and Sushrut Babhulkar

submission deadline 20 Sep 2026 | 7 articles | Viewed by 11888 | Submission Open

Keywords: musculoskeletal disorders; disability; pain; inflammation; arthritis

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in Clinical Exercise for Health

edited by

Pedro Miguel Forte

and Joana Ribeiro

submission deadline 20 Sep 2026 | 7 articles | Viewed by 11681 | Submission Open

Keywords: clinical exercise science; physical activity; chronic disease prevention; biomechanics; healthy aging; physiology

(This special issue belongs to the Section Sports Medicine)

Current Challenges and New Perspectives in Liver Transplantation

edited by

Anna Mrzljak

and

Quirino Lai

submission deadline 20 Sep 2026 | 9 articles | Viewed by 9785 | Submission Open

Keywords: liver transplantation; graft survival; immunosuppression; organ allocation; hepatocellular carcinoma; MASLD; donor shortage; transplant outcomes; innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Perspectives on the Diagnosis and Treatment of Cardiomyopathies

edited by Luca Arcari

submission deadline 20 Sep 2026 | 5 articles | Viewed by 8759 | Submission Open

Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging

(This special issue belongs to the Section Cardiology)

Thoracic Surgery: State of the Art and Future Directions

edited by

Ugo Cioffi

and

Marco Scarci

submission deadline 20 Sep 2026 | 6 articles | Viewed by 8638 | Submission Open

Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum

(This special issue belongs to the Section Respiratory Medicine)

Cognitive Impairment, Dementia and Depression in Older Adults

edited by Seong Jae Kim and Ilhan Choo

submission deadline 20 Sep 2026 | 3 articles | Viewed by 6659 | Submission Open

Keywords: cognitive impairment; dementia; depression; Parkinson’s disease; artificial intelligence (AI); predictive modeling

(This special issue belongs to the Section Geriatric Medicine)

Advances in Minimally Invasive Gynecologic Surgery: Optimizing Outcomes and Perioperative Strategies

edited by

Raanan Meyer

submission deadline 20 Sep 2026 | 3 articles | Viewed by 5338 | Submission Open

Keywords: minimally invasive gynecologic surgery; MIGS; laparoscopy; robotic surgery; endometrial cancer; endometriosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood

edited by Kamila Chęcińska and

Maciej Sikora

submission deadline 20 Sep 2026 | 5 articles | Viewed by 5227 | Submission Open

Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Advances in Systemic Lupus Erythematosus (SLE)

edited by

Chang-Hee Suh

submission deadline 20 Sep 2026 | 2 articles | Viewed by 5125 | Submission Open

Keywords: systemic lupus erythematosus; autoantibodies and biomarkers; lupus nephritis; new and novel treatments; targeted treatment or precision medicine; quality of life

(This special issue belongs to the Section Immunology & Rheumatology)

Modern Gynecological Surgery: Clinical Updates and Perspectives

edited by

Rudy Leon De Wilde

Harald Krentel

and Maya Sophie de Wilde

submission deadline 20 Sep 2026 | 4 articles | Viewed by 4916 | Submission Open

Keywords: gynecological diseases; gynecological surgery; surgical options; individual treatment; women’s health care

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Antithrombotic Therapy in Cardiovascular Medicine

edited by Daniele Giacoppo and Antonio Greco

submission deadline 20 Sep 2026 | 6 articles | Viewed by 4206 | Submission Open

Keywords: anticoagulant; antiplatelet; antithrombotic therapy; cardiovascular pharmacotherapy; coronary artery disease; in-flammation; lipid-lowering drugs; lipid metabolism; residual cardiovascular risk; thrombosis

(This special issue belongs to the Section Cardiovascular Medicine)

Displaying special issue 151-200 on page 4 of 31.

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