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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gastroparesis: Emerging Insights and Endoscopic Therapeutic Strategies

edited by Sabrina Testoni

submission deadline 20 Mar 2027 | Viewed by 354 | Submission Open

Keywords: gastroparesis; gastric dismotility; gastric emptying; gastric per-oral miotomy; pyloromyotomy; gastric electric stim-ulation; botulinum toxin

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances in Pediatric Hepatobiliary Surgery

edited by Ioannis A. Ziogas

submission deadline 20 Mar 2027 | Viewed by 353 | Submission Open

Keywords: pediatric hepatobiliary surgery; pediatric transplantation; pediatric surgery; liver transplantation; biliary atresia; choledochal cyst; liver cancer

(This special issue belongs to the Section Clinical Pediatrics)

New Clinical Insight: From Open Surgery to Minimally Invasive Foot and Ankle Surgery

edited by Enrique A. Testa and Daniel Poggio

submission deadline 20 Mar 2027 | Viewed by 352 | Submission Open

Keywords: minimally invasive surgery; foot surgery; ankle surgery; trauma surgery; orthopedic surgery; ankle arthroscopy

(This special issue belongs to the Section Orthopedics)

Neuroimmunology in Neurological Disorders: Clinical Diagnosis and Treatment

edited by Charalampos Skarlis,

Maria Anagnostouli

and

Evangelia Liouta

submission deadline 20 Mar 2027 | Viewed by 351 | Submission Open

Keywords: neuroimmunology; neuroinflammation; neurodegenerative diseases; Parkinson’s disease; multiple sclerosis; CNS autoimmune disease; biomarkers; immunomodulatory therapy

(This special issue belongs to the Section Clinical Neurology)

Colorectal Surgery: Current Concept and Emerging Trends

edited by

Valentin Calu

submission deadline 20 Mar 2027 | Viewed by 336 | Submission Open

Keywords: colorectal surgery; robotic surgery; neoadjuvant treatment; minimally invasive techniques; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Optimizing Outcomes in Pancreato-Biliary Care: Integrating Technology, Technique, and Personalized Approaches

edited by

Andrea Tufo

submission deadline 20 Mar 2027 | Viewed by 321 | Submission Open

Keywords: pancreato-biliary care; pancreatic diseases; biliary diseases; hepato-pancreato-biliary (HPB) surgery; interventional endoscopy; interventional radiology; minimally invasive surgery; EUS-guided procedures; ERCP; personalized care/personalized medicine; multidisciplinary care; clinical outcomes; robotics and AI in PB care

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Contactless Magnetocardiography and Related Novel Methods for Non-Invasive Experimental and Clinical Functional Imaging of Normal and Abnormal Cardiac Electrophysiology

edited by

Riccardo Fenici

Donatella Brisinda

and

Peter Fenici

submission deadline 20 Mar 2027 | Viewed by 263 | Submission Open

Keywords: magnetocardiography; non-invasive functional imaging of cardiac electrophysiology; arrhythmogenic mechanisms; atrial fibrillation; magnetoionography; antiarrhythmic drugs; artificial intelligence

(This special issue belongs to the Section Cardiology)

Head and Neck Surgery: Immunotherapy’s Role in Shaping Treatment Paradigms

edited by

Mark S. Swanson

submission deadline 20 Mar 2027 | Viewed by 257 | Submission Open

Keywords: head and neck surgery; otorhinolaryngology; ENT; transoral surgery; laryngeal surgery; laryngeal carcinoma; sinonasal surgery; oral cancer; oropharyngeal cancer; laryngectomy; immunotherapy; head and neck cancer; cutaneous cancer

(This special issue belongs to the Section Otolaryngology)

Game-Changing Advances in Minimally Invasive Spine Surgery

edited by Rouzbeh Motiei-Langroudi

submission deadline 20 Mar 2027 | Viewed by 251 | Submission Open

Keywords: minimally invasive spine surgery (MISS); technological innovation; navigation systems/robotic-assisted; endoscopic techniques; artificial intelligence/machine learning

(This special issue belongs to the Section Clinical Neurology)

Advances in Mental Health: All Ages and Multidisciplinary Clinical Perspectives

edited by Clara González-Sanguino and

Jairo Rodríguez-Medina

submission deadline 20 Mar 2027 | Viewed by 196 | Submission Open

Keywords: stigma; discrimination; mental health; clinical psychology; depression and anxiety

(This special issue belongs to the Section Mental Health)

Clinical Advances in Extracorporeal Membrane Oxygenation (ECMO)—Second Edition

edited by

Sung-Min Cho

and

Akram Zaaqoq

submission deadline 20 Mar 2027 | 1 articles | Viewed by 177 | Submission Open

Keywords: extracorporeal membrane oxygenation; ECMO; multi-organ failure; outcomes; V-A ECMO; ECPR; V-V ECMO; translational research; clinical research

(This special issue belongs to the Section Intensive Care)

Clinical Physical Therapy: Current Advances and Future Challenges

edited by

Andreas Brandl

and

Robert Schleip

submission deadline 20 Mar 2027 | Viewed by 149 | Submission Open

Keywords: clinical physical therapy; chronic musculoskeletal disorders; chronic pain management; manual therapy; mind–body medicine; biopsychosocial model; autoimmune diseases; fatigue syndromes; bottom-up and top-down regulation; neurophysiological mechanisms

(This special issue belongs to the Section Clinical Rehabilitation)

Psychosis Across Disciplines: Emerging Perspectives in Neuroscience, Psychiatry, and Therapy

edited by Inmaculada Peñuelas-Calvo, Roberto Rodríguez-Jiménez and

Lorena García-Fernández

submission deadline 20 Mar 2027 | Viewed by 147 | Submission Open

Keywords: psychosis; lifespan; neuroimaging; psychotherapy; prevention

(This special issue belongs to the Section Mental Health)

Clinical Updates in Type 2 Diabetes and Related Complications

edited by

Ilias Migdalis

submission deadline 20 Mar 2027 | Viewed by 144 | Submission Open

Keywords: type 2 diabetes; chronic complications; microvascular disease; macrovascular disease; treatment

(This special issue belongs to the Section Endocrinology & Metabolism)

Advancing Precision Care in Neuropathic Pain: From Biomarkers to Neuromodulation to Artificial Intelligence

edited by Saurabh Kataria and

Jeremiah Hilkiah Wijaya

submission deadline 20 Mar 2027 | Viewed by 142 | Submission Open

Keywords: neuropathic pain; precision medicine; neuromodulation; spinal cord stimulation; peripheral nerve stimulation; ul-trasound-guided interventions; pain phenotyping; personalized therapeutics; opioid alternatives

(This special issue belongs to the Section Clinical Neurology)

Therapies for Heart Failure: Clinical Updates and Perspectives: 2nd Edition

edited by Cristina Tudoran, Stela Iurciuc and

Dragos Cozma

submission deadline 20 Mar 2027 | Viewed by 133 | Submission Open

Keywords: mechanisms of heart failure; new therapies for heart failure; chronic and acute heart failure; new approaches to managing heart failure patients; special populations; clinical outcome

(This special issue belongs to the Section Cardiology)

Recent Advances in Clinical Perspectives on the Diagnosis and Treatment of Endometriosis

edited by Paweł Basta and

Krzysztof Gałczyński

submission deadline 20 Mar 2027 | Viewed by 131 | Submission Open

Keywords: endometriosis; deep endometriosis; endometrioma; infertility; laparoscopy; minimally invasive techniques; biomarkers; pain; pelvic pain; adenomyosis; adhesions; dysmenorrhea; dyspareunia

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Challenges and Advances in Hepatobiliary and Pancreatic Surgery

edited by

Marco Massani

and

Alessandro Veltri

submission deadline 20 Mar 2027 | Viewed by 131 | Submission Open

Keywords: pancreatic cancer; pancreatic cancer surgery; neoadjuvant chemotherapy; perioperative management; surgical approaches

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The State of the Art in Robotic Thoracic Surgery: Innovation, Complexity and Outcomes

edited by Michael Zervos

submission deadline 20 Mar 2027 | Viewed by 121 | Submission Open

Keywords: thoracic surgery; robotic surgery; single-port robotic surgery; robotic-assisted thoracic surgery; minimally invasive surgery; lung cancer

(This special issue belongs to the Section General Surgery)

Gastrointestinal Surgery: New Insights into Tumor Metabolism and Translational Oncology

edited by Konstantinos Romanidis

submission deadline 20 Mar 2027 | Viewed by 110 | Submission Open

Keywords: gastrointestinal cancer; tumor metabolism; translational oncology; surgical oncology; metabolic profiling; artificial intelligence

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Developmental Transfusion Biology in Neonatal–Perinatal Medicine

edited by Thomas G. Brune

submission deadline 20 Mar 2027 | Viewed by 103 | Submission Open

Keywords: neonatal transfusion; preterm infants; fetal hemoglobin; cord blood; delayed cord clamping; oxygen transport; developmental hematology

(This special issue belongs to the Section Clinical Pediatrics)

Dentistry and Oral Surgery: Current Status and Future Prospects, 2nd Edition

edited by

Dragana Gabrić

Marko Vuletić

and

Igor Smojver

submission deadline 20 Mar 2027 | Viewed by 79 | Submission Open

Keywords: dentistry; oral surgery; dental implantology; prosthodontics; restorative dentistry; periodontology; digital dentistry; computer-guided surgery; artificial intelligence

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Neuro-Oncology: Diagnostics and Treatment

edited by

Jigisha P. Thakkar

and Derek A. Wainwright

submission deadline 20 Mar 2027 | Viewed by 77 | Submission Open

Keywords: glioblastoma; glioma; meningioma; brain metastases; blood–brain barrier

(This special issue belongs to the Section Clinical Neurology)

Diagnostic and Interventional Radiology: Advances in Treatment of Small Tumors

edited by Carolina Lanza

submission deadline 20 Mar 2027 | Viewed by 68 | Submission Open

Keywords: interventional radiology; MRI; contrast-enhanced ultrasound; CT; liver; kidney; lung; prostate; breast; multimodal imaging; diagnostic imaging; tumor

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Sarcopenia: Prevention and Treatment Options

edited by Steven Phu

submission deadline 21 Mar 2027 | 3 articles | Viewed by 1687 | Submission Open

Keywords: sarcopenia; skeletal muscle; ageing; falls; frailty; exercise; rehabilitation; nutrition

(This special issue belongs to the Section Geriatric Medicine)

Clinical Research on Robot-Assisted Thoracic Surgery and Lung Surgery

edited by Marco Scarci

submission deadline 21 Mar 2027 | 1 articles | Viewed by 907 | Submission Open

Keywords: robot-assisted thoracic surgery; robotic lung surgery; minimally invasive surgery; lobectomy; segmentectomy; thoracic oncology; surgical outcomes; learning curve; clinical research; robotic technology

(This special issue belongs to the Section General Surgery)

Macular Diseases: From Diagnosis to Treatment

edited by

Gabriella De Salvo

submission deadline 22 Mar 2027 | 3 articles | Viewed by 2799 | Submission Open

Keywords: age-related macular degeneration; retinal vascular diseases; intraocular tumours; retinal imaging; OCT; OCT angiography; anti-VEGF; laser therapy; macular surgery; gene therapy; biomarkers; progression; intravitreal injections; biomarkers

(This special issue belongs to the Section Ophthalmology)

Psychological Affliction in Pregnancy, Delivery and Postpartum Period: A Multidisciplinary Approach

edited by

Beata Pięta

and

Edyta Barnas̈

submission deadline 24 Mar 2027 | 4 articles | Viewed by 2672 | Submission Open

Keywords: maternal mental health; pregnancy; postpartum depression; perinatal anxiety; midwifery; multidisciplinary care

(This special issue belongs to the Section Mental Health)

Rewriting Metastatic Colorectal Cancer Management: Innovative Frontiers in Clinical Diagnosis and Personalized Oncology

edited by

Maria Maddalena Laterza

submission deadline 24 Mar 2027 | Viewed by 392 | Submission Open

Keywords: molecular profiling; liquid biopsy; targeted therapy; immunotherapy; biomarkers treatment; sequencing; tumor heterogeneity; personalized medicine

(This special issue belongs to the Section Oncology)

Emergency Surgery: Clinical Updates and Key Insights

edited by

Dragos Serban

submission deadline 24 Mar 2027 | Viewed by 119 | Submission Open

Keywords: minimally invasive emergency surgery; biomarkers; point-of-care imaging (POCI); frailty assessment; surgical decision-making; risk stratification; damage control surgery; enhanced recovery (ERAS); patient outcomes; multidisciplinary care

(This special issue belongs to the Section Emergency Medicine)

Obstructive Sleep Apnea: Advances in Clinical Diagnosis and Management

edited by

Gonzalo Labarca

submission deadline 25 Mar 2027 | 7 articles | Viewed by 7636 | Submission Open

Keywords: obstructive sleep apnea; sleep disorder breathing; central apnea; apnea–hypopnea index; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Thoracic Surgery: Updates and New Trends

edited by

Monica Casiraghi

submission deadline 25 Mar 2027 | 4 articles | Viewed by 7220 | Submission Open

Keywords: minimally invasive surgery; new technology; diagnosis; bronchoscopy; robotic system; artificial intelligence

(This special issue belongs to the Section Respiratory Medicine)

Update on Acute Severe Respiratory Infections: 2nd Edition

edited by

Jean-Francois Timsit

submission deadline 25 Mar 2027 | 6 articles | Viewed by 6118 | Submission Open

Keywords: acute severe respiratory infection (ASRI); acute respiratory distress syndrome (ARDS); severe pneumonia; sepsis; ICU; viral respiratory infection; COVID-19; bacterial co-infection; diagnostic technology; treatment strategy; mechanical ventilation; extracorporeal membrane oxygenation (ECMO); antibiotics; non-antibiotics; pulmonary rehabilitation

(This special issue belongs to the Section Respiratory Medicine)

Sleep Disorders: Current Research and Future Directions—Second Edition

edited by Martina Vendrame

submission deadline 25 Mar 2027 | 6 articles | Viewed by 5056 | Submission Open

Keywords: obstructive sleep apnea; parasomnia; idiopathic hypersomnia; periodic limb movement disorder; periodic limb move-ment of sleep

(This special issue belongs to the Section Clinical Neurology)

Aortic Diseases: Modern Strategies in Diagnosis, Management, and Prevention of Complications

edited by

Petroula N. Nana

, Tilo Kölbel and José Ignacio F. Torrealba

submission deadline 25 Mar 2027 | 7 articles | Viewed by 4727 | Submission Open

Keywords: aortic aneurysm; aortic dissection; genetic aortic disease; acute aortic syndromes; endovascular repair; complica-tions; outcomes

(This special issue belongs to the Section Vascular Medicine)

Applications of Artificial Intelligence and Digital Therapeutics in Clinical Medicine: 2nd Edition

edited by

Carlos Escobar

submission deadline 25 Mar 2027 | 3 articles | Viewed by 4049 | Submission Open

Keywords: artificial intelligence; biometric sensors; deep learning; digital therapies; Internet of Things; machine learning; virtual reality; augmented reality

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)

Clinical Advances in Prenatal Diagnosis and Fetal Therapy

edited by

Mar Bennasar

submission deadline 25 Mar 2027 | 3 articles | Viewed by 3950 | Submission Open

Keywords: prenatal diagnosis; fetal therapy; genetic screening; non-invasive testing; fetal surgery; imaging technologies; high-risk pregnancies; in utero treatments; stem cell therapies; clinical innovations

(This special issue belongs to the Section Obstetrics & Gynecology)

Obesity in the 2020s and Beyond: A Multidisciplinary Overview

edited by

Andrej Belančić

submission deadline 25 Mar 2027 | 2 articles | Viewed by 3365 | Submission Open

Keywords: obesity; anti-obesity pharmacotherapy; clinical pharmacology; pharmacovigilance; cardiometabolic diseases

(This special issue belongs to the Section Pharmacology)

Endoscopic Management of Pancreaticobiliary Diseases

edited by

Kamran Ayub

submission deadline 25 Mar 2027 | 4 articles | Viewed by 2888 | Submission Open

Keywords: pancreaticobiliary endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); biliary drainage; gallbladder drainage; lumen-opposing metal stents; cholangioscopy; pancreatoscopy; confocal laser endomicroscopy; pancreatic cysts; molecular diagnostics; lithotripsy (electrohydraulic and laser); radiofrequency ablation (RFA); photodynamic therapy (PDT); pancreatic and biliary tumors; interventional endoscopy; altered anatomy access; diagnostic and therapeutic endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Strategies for Preventing Healthcare-Associated Infections

edited by

Monica Marilena Țânțu

Rogozea Liliana Marcela

and

Corneliu Ovidiu Vrancianu

submission deadline 25 Mar 2027 | 2 articles | Viewed by 2816 | Submission Open

Keywords: healthcare-associated infections; multidrug resistance; prevention; screening scales; polymicrobial infections; oppor-tunistic infections; sepsis

(This special issue belongs to the Section Infectious Diseases)

New Advances in Hip and Knee Reconstructive Surgery: 2nd Edition

edited by Senthil Sambandam

submission deadline 25 Mar 2027 | 2 articles | Viewed by 1805 | Submission Open

Keywords: knee; hip; joint arthroplasty; minimally invasive surgery; revision arthroplasty; periprosthetic joint infection; muscle injury; joint alignment; surgical advances; osteotomy; fracture; robotic-assisted surgery; perioperative optimization; telerehabilitation; aseptic loosening

(This special issue belongs to the Section Orthopedics)

Segmentectomy and Lobectomy in Early-Stage Lung Cancer Management

edited by Yujin Kudo

submission deadline 25 Mar 2027 | 1 articles | Viewed by 1200 | Submission Open

Keywords: lung cancer; segmentectomy; lobectomy; thoracic surgery; early-stage NSCLC; oncologic outcomes; pulmonary function; surgical planning

(This special issue belongs to the Section Respiratory Medicine)

Exercise for Healthy Aging: Clinical Physiology, Functional Outcomes, and Implications for Clinical Practice

edited by

Jerónimo Aragón-Vela

and

Rafael A. Casuso

submission deadline 25 Mar 2027 | 1 articles | Viewed by 977 | Submission Open

Keywords: exercise; healthy aging; functional independence; mitochondrial adaptations; physical activity interventions; neuromuscular function; cardiorespiratory fitness; metabolic health; biomarkers of aging

(This special issue belongs to the Section Sports Medicine)

Innovations in Elbow and Shoulder Surgery: Techniques, Outcomes, and Rehabilitation

edited by Andrea Celli

submission deadline 25 Mar 2027 | Viewed by 452 | Submission Open

Keywords: orthopedic; elbow surgery; shoulder surgery; infection; nonunion; malunion; ligaments injuries; tendon injuries; el-bow and shoulder replacement; arthroscopy

(This special issue belongs to the Section Orthopedics)

Integrated Assessment and Management of Heart Failure Syndromes

edited by Damiano Magrì and Emiliano Fiori

submission deadline 25 Mar 2027 | Viewed by 318 | Submission Open

Keywords: heart failure; functional capacity; multimodality assessment; advanced imaging; coronary and structural interventions; device therapies

(This special issue belongs to the Section Cardiology)

Advances in Cardiac Electrophysiology: Mechanisms of Arrhythmias and Ablation Technologies

edited by

Federico Landra

, Valeria Rella and Emanuele Curti

submission deadline 25 Mar 2027 | Viewed by 204 | Submission Open

Keywords: cardiac arrhythmias; cardiac electrophysiology; arrhythmias pathophysiology; arrhythmia mechanisms; catheter ablation; electro-anatomical mapping; mapping techniques; pacing maneuvers; pulsed field ablation; radiofrequency; autonomic modulation; cardioneuroablation; imaging; hybrid ablation; clinical outcomes

(This special issue belongs to the Section Cardiology)

Advanced and Personalized Drug Delivery Systems: From Formulation Science to Clinical Application

edited by

Hudson C. Polonini

submission deadline 25 Mar 2027 | Viewed by 163 | Submission Open

Keywords: drug delivery systems; nanoparticles; lipid-based carriers; transdermal delivery; controlled release; bioavailability; pharmaceutical nanotechnology; personalized medicine; polymeric carriers; targeted therapy; in vitro–in vivo cor-relation; pharmaceutical compounding; stimuli-responsive drug delivery; clinical pharmacokinetics; innovative dosage forms

(This special issue belongs to the Section Pharmacology)

Minimally Invasive Approaches in Hand Surgery: Optimizing Outcomes and Minimizing Complications

edited by

Hyunil Lee

submission deadline 25 Mar 2027 | Viewed by 161 | Submission Open

Keywords: percutaneous technique; ultrasound-guided procedures; arthroscopic management; robotic surgery in the hand and upper extremity; hand surgery

(This special issue belongs to the Section Orthopedics)

Insights into Infectious Disease Epidemiology, Management and Impact on Public Health

edited by Krystyna Dobrowolska,

Agnieszka Walczyk

and

Piotr Lewitowicz

submission deadline 25 Mar 2027 | Viewed by 141 | Submission Open

Keywords: infectious disease; viral infections; bacterial infections; epidemiology; public health

(This special issue belongs to the Section Epidemiology & Public Health)

Current Updates and Advances in Hemodialysis—2nd Edition

edited by Edita Žiginskienė

submission deadline 25 Mar 2027 | Viewed by 104 | Submission Open

Keywords: kidney replacement therapy; hemodialysis; hemodiafiltration; vascular access; dialysis membranes; dialysis complications; dialysis adequacy; outcomes

(This special issue belongs to the Section Nephrology & Urology)

Displaying special issue 1151-1200 on page 24 of 30.

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