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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Meibomian Gland Dysfunction and Dry Eye Diseases
edited by and
submission deadline 25 Sep 2026 | 5 articles | Viewed by 3580 | Submission Open
Keywords: meibomian gland; meibomian gland dysfunction; dry eye disease; ocular surface; meibography; lipid layer; tear film; inflammation; therapy; diagnosis; epidemiology; clinical study
(This special issue belongs to the Section Ophthalmology)
Diagnosis and Treatment for Hearing Loss: Expert Views
edited by and John L. Dornhoffer
submission deadline 25 Sep 2026 | 2 articles | Viewed by 2661 | Submission Open
Keywords: hearing loss; cochlear implants; hearing aid technology; regenerative medicine; diagnostic audiology
(This special issue belongs to the Section Otolaryngology)
New Clinical Advances in Sudden Cardiac Arrest and Ventricular Arrhythmias: 2nd Edition
edited by
submission deadline 25 Sep 2026 | 1 articles | Viewed by 2558 | Submission Open
Keywords: cardiac arrest; defibrillation; ventricular tachycardia; ventricular fibrillation; catheter ablation; non-invasive ablation; neuromodulation; stellate ganglion block
(This special issue belongs to the Section Cardiology)
Current Advances and Future Perspectives of Sepsis and Septic Shock
edited by Filippo Mearelli and Gianni Biolo
submission deadline 25 Sep 2026 | 2 articles | Viewed by 2251 | Submission Open
Keywords: sepsis; epidemiology; biomarkers; diagnosis; predictive models; prognostication
(This special issue belongs to the Section Emergency Medicine)
Latest Advances in Ocular Surface Diseases
edited by Barbara Burgos-Blasco
submission deadline 25 Sep 2026 | 2 articles | Viewed by 1998 | Submission Open
Keywords: cornea; keratitis; ocular surface disease; dry eye; corneal ulcer; keratoplasty; conjunctival disease
(This special issue belongs to the Section Ophthalmology)
Latest Advances in Minimally Invasive Spine Surgery
edited by Fabian Sommer and
submission deadline 25 Sep 2026 | 2 articles | Viewed by 1833 | Submission Open
Keywords: minimally invasive spine surgery (MISS); advances in spine surgery; future directions of MISS; navigation and orientation; intramedullary/extramedullary tumor resections; emerging technologies in MISS (robotics, augmented reality, artificial intelligence, etc.); degenerative spine; patient safety in MISS
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates and Perspectives in Atrial Fibrillation
edited by Riyaz Somani and
submission deadline 25 Sep 2026 | 1 articles | Viewed by 1516 | Submission Open
Keywords: atrial fibrillation; catheter ablation; risk prediction; stroke prevention; digital health and artificial intelligence
(This special issue belongs to the Section Cardiology)
Corneal Surgery: From Innovation to Clinical Practice
edited by Joanna Wasielica-Poslednik
submission deadline 25 Sep 2026 | 1 articles | Viewed by 1484 | Submission Open
Keywords: keratoplasty; penetrating keratoplasty; DMEK; eye banking; corneal surgery
(This special issue belongs to the Section Ophthalmology)
Idiopathic Thrombocytopenic Purpura (ITP) and Thrombotic Thrombocytopenic Purpura (TTP): Pathophysiology, Clinical Practice and Future Developments
edited by María Eva Mingot Castellano
submission deadline 25 Sep 2026 | 2 articles | Viewed by 1441 | Submission Open
Keywords: ITP; TTP; thrombocytopenia; autoimmune; bleeding; thrombosis; caplacizumab; steroids; plasma exchange; infections; thrombopoetin; thrombopoetin analogs; immunosuppressive; immunomodulation; quality of life; fatigue
(This special issue belongs to the Section Hematology)
Emergency Surgery: Recent Advances and Practical Strategies
edited by Avi Benov
submission deadline 25 Sep 2026 | 2 articles | Viewed by 1253 | Submission Open
Keywords: emergency surgery; acute care surgery; trauma; prehospital care; early decision-making; clinical outcomes; risk stratification; real-world evidence; registries
(This special issue belongs to the Section Emergency Medicine)
Tendon and Ligament Injury and Current Strategies for Tendon and Ligament Regeneration
edited by Andrej Čretnik, Bore Bakota and Dejan Blažević
submission deadline 25 Sep 2026 | 1 articles | Viewed by 1063 | Submission Open
Keywords: tendons; ligaments; injuries; tendinopathies; minimally invasive surgery; functional treatment; tissue engineering; novelties
(This special issue belongs to the Section Orthopedics)
Clinical Advances in General and Regional Anesthesia
edited by Luciano Frassanito
submission deadline 25 Sep 2026 | 1 articles | Viewed by 1058 | Submission Open
Keywords: oncoanesthesia; perinatal anesthesia; ventilatory support; hemodynamic monitoring; regional anesthesia
(This special issue belongs to the Section Anesthesiology)
Deep Vein Thrombosis and Pulmonary Embolism: Current Clinical Treatment and Management
edited by Windsor Ting
submission deadline 25 Sep 2026 | 1 articles | Viewed by 864 | Submission Open
Keywords: deep vein thrombosis; pulmonary embolus; vein stenosis. iliac vein stenosis; May-Thurner syndrome; thoracic outlet syndrome; renal vein stenosis; nutcracker syndrome
(This special issue belongs to the Section Vascular Medicine)
Coronary Intervention: Current Strategies and Future Directions
edited by
submission deadline 25 Sep 2026 | 1 articles | Viewed by 840 | Submission Open
Keywords: coronary intervention; percutaneous coronary intervention; complex PCI; intravascular imaging; coronary physiology; antiplatelet therapy; cardiovascular outcomes
(This special issue belongs to the Section Cardiovascular Medicine)
Gastrointestinal Surgery and Pain Management: Contemporary Advances and Clinical Insights
edited by
submission deadline 25 Sep 2026 | 1 articles | Viewed by 656 | Submission Open
Keywords: gastrointestinal surgery; postoperative pain; chronic pain; acute pain; perioperative care; pain management; multimodal analgesia; enhanced recovery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Ocular Microcirculation and Clinical Outcomes in Ophthalmic Diseases
edited by Robert Rejdak and
submission deadline 25 Sep 2026 | 1 articles | Viewed by 605 | Submission Open
Keywords: ocular microcirculation; clinical outcomes; diabetic retinopathy; glaucoma; optic nerve diseases; ocular blood flow; ophthalmic diseases; retinal disorders; imaging techniques; hemodynamics
(This special issue belongs to the Section Ophthalmology)
Myeloid-Derived Suppressor and Innate Immune Cells in Hematologic, Malignant and Chronic Diseases
edited by
submission deadline 25 Sep 2026 | Viewed by 457 | Submission Open
Keywords: myeloid-derived suppressor cells (MDSCs); macrophages; monocytes; eosinophils; neutrophils; malignancy; cancer; autoimmunity; infection; chronic inflammation; therapeutic target; biomarker; precision medicine; molecular pathways; bone marrow microenvironment
(This special issue belongs to the Section Hematology)
From Heart to Brain: Interdisciplinary Perspectives on Cerebral Infarction
edited by and Jean-Claude Deharo
submission deadline 25 Sep 2026 | Viewed by 341 | Submission Open
Keywords: ischemic stroke; cardioembolic stroke; atrial fibrillation; heart–brain axis; neurocardiology; post-stroke cardiac dysfunction; stroke prevention; cerebral infarction; cardiac monitoring in stroke; secondary stroke prevention
(This special issue belongs to the Section Clinical Neurology)
Advances in the Diagnosis and Management of Sarcoidosis
edited by , Pilar Brito-Zerón and Miriam Akasbi Montalvo
submission deadline 25 Sep 2026 | Viewed by 338 | Submission Open
Keywords: sarcoidosis; diagnosis; biomarkers; imaging; immunopathogenesis; biologic therapy; prognosis; interstitial lung disease
(This special issue belongs to the Section Immunology & Rheumatology)
Robotic Urologic Surgery: Applications and Prospects
edited by
submission deadline 25 Sep 2026 | Viewed by 274 | Submission Open
Keywords: urology; robotic surgery; RAPN; RARP; robotic procedures
(This special issue belongs to the Section General Surgery)
Current Treatment on Urinary Tract Infection
edited by
submission deadline 25 Sep 2026 | Viewed by 262 | Submission Open
Keywords: urinary tract infections (UTIs); antibiotic resistance; probiotics and alternative therapies; diagnostic advancements; urinary infection management
(This special issue belongs to the Section Nephrology & Urology)
Innovative Approaches to the Epidemiology, Diagnosis, and Treatment of Systemic Sclerosis submission deadline 25 Sep 2026 | Viewed by 257 | Submission Open
Keywords: systemic sclerosis; scleroderma; epidemiology; biomarkers; personalized therapy; therapeutic strategies
(This special issue belongs to the Section Clinical Neurology)
Diagnosis, Treatment and Prognosis of Benign Prostatic Hyperplasia and Prostate Cancer
edited by Christian Wetterauer
submission deadline 25 Sep 2026 | Viewed by 222 | Submission Open
Keywords: benign prostatic hyperplasia; prostate cancer; urology; urological oncology; oncological outcomes; risk stratification; benign prostatic obstruction; minimally invasive techniques; artificial intelligence
(This special issue belongs to the Section Nephrology & Urology)
Lifelong Care in Congenital Heart Disease
edited by
submission deadline 25 Sep 2026 | Viewed by 213 | Submission Open
Keywords: fetal echocardiography; pediatric cardiology; adults with congenital heart disease (ACHD); transition of care; cardio-obstetrics; heart failure; pregnancy; advanced imaging; echocardiography; cardiovascular risk prevention
(This special issue belongs to the Section Cardiovascular Medicine)
Challenges and Clinical Surveillance in Cerebral Aneurysm Management
edited by Joseph Antonios
submission deadline 25 Sep 2026 | Viewed by 212 | Submission Open
Keywords: intracranial aneurysm; cerebral aneurysm surveillance; risk stratification; aneurysm progression; vascular inflammation
(This special issue belongs to the Section Clinical Neurology)
Mitral Valve Stenosis or Aortic Valve Stenosis: Progress from Diagnosis to Treatment
edited by Francesco Melillo
submission deadline 28 Sep 2026 | 3 articles | Viewed by 7590 | Submission Open
Keywords: aortic stenosis; mitral stenosis; TAVI
(This special issue belongs to the Section Cardiology)
Management of Female Pelvic Floor Disorders and Incontinence
edited by Luis López Fando
submission deadline 28 Sep 2026 | 2 articles | Viewed by 2174 | Submission Open
Keywords: pelvic floor disorders; urinary incontinence; pelvic organ prolapse; reconstructive urology; voiding dysfunction; multidisciplinary care; surgical techniques; urodynamics; patient-centered outcomes; digital learning in urology
(This special issue belongs to the Section Nephrology & Urology)
Current Challenges in Oral Surgery and Pathology
edited by
submission deadline 28 Sep 2026 | 2 articles | Viewed by 1724 | Submission Open
Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Clinical Perspective in Kidney Transplantation
edited by Nikolina Bašić-Jukić
submission deadline 29 Sep 2026 | 7 articles | Viewed by 5972 | Submission Open
Keywords: kidney transplantation; outcomes; desensitization; xenotransplantation; transplant nephropathology; multiorgan transplantations; post-transplant complications; inequities in transplantation
(This special issue belongs to the Section Nephrology & Urology)
Glaucoma: Diagnosis and Management Insights
edited by and Efthymios Karmiris
submission deadline 29 Sep 2026 | 3 articles | Viewed by 2422 | Submission Open
Keywords: glaucoma; risk factors; progression; novel biomarkers; diagnosis; management
(This special issue belongs to the Section Ophthalmology)
New Insights into Cardiovascular Radiology
edited by Amalia Lupi and
submission deadline 29 Sep 2026 | 3 articles | Viewed by 1625 | Submission Open
Keywords: CMR; tissue characterization; 4Dflow; CCTA; photon counting CT; plaque characterization
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Advances in Musculoskeletal Physiotherapy: Exercise, Manual Therapy and Invasive Physiotherapy
edited by and Ignacio Cancela-Cilleruelo
submission deadline 30 Sep 2026 | 6 articles | Viewed by 21360 | Submission Open
Keywords: musculoskeletal disorders; exercise therapy; manual therapy; invasive physical therapy; rehabilitation
(This special issue belongs to the Section Orthopedics)
Catheter Ablation of Cardiac Arrhythmias: Current Updates and Perspectives: 2nd Edition
edited by
submission deadline 30 Sep 2026 | 3 articles | Viewed by 7079 | Submission Open
Keywords: ablation; arrhythmia; electrophysiology; atrial fibrillation; atrial flutter; atrial tachycardia; mapping; supraventricular tachycardia; ventricular arrhythmia
(This special issue belongs to the Section Cardiology)
Clinical Updates on Dyslipidemia
edited by
submission deadline 30 Sep 2026 | 4 articles | Viewed by 5005 | Submission Open
Keywords: dyslipidemia; cardiovascular disease; prevention; treatment; risk factors
(This special issue belongs to the Section Cardiovascular Medicine)
Artificial Intelligence in Women’s Health and Medicine: Improving Clinical Practice, Diagnosis, Treatment Management and Patient Experiences
edited by and Nasibeh Zanjirani Farahani
submission deadline 30 Sep 2026 | 1 articles | Viewed by 4190 | Submission Open
Keywords: women’s health; artificial intelligence; machine learning; personalized medicine; reproductive health; health equity; social determinants of health; mental health; cancer; cardiovascular disease
(This special issue belongs to the Section Epidemiology & Public Health)
Clinical Advances in Hepatology submission deadline 30 Sep 2026 | 2 articles | Viewed by 3399 | Submission Open
Keywords: cirrhosis; portal hypertension; non-invasive tests; viral hepatitis; MASLD; HCC
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Targeted Management of Orofacial Pain: From Pharmacology to Temporomandibular Joint Surgery
edited by , and Giulia Ottaviani
submission deadline 30 Sep 2026 | 2 articles | Viewed by 1269 | Submission Open
Keywords: orofacial pain; chronic orofacial pain; neuropathic pain; pharmacological management; temporomandibular joint disorders; degenerative TMJ disease; conservative treatment; surgical management
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Modern Oral Surgery and Periodontology: Technological Advances, Innovation, and Clinical Applications
edited by Rafał Wiench and
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1231 | Submission Open
Keywords: oral surgery; periodontology; periodontal regeneration; implant dentistry; peri-implant diseases, guided surgery; biomaterials; platelet concentrates (PRF, PRP); bone regeneration
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Burnout and Anxiety in Clinical and Occupational Contexts: Mental Health, Work-Related Stress, and Vulnerable Populations submission deadline 30 Sep 2026 | 1 articles | Viewed by 899 | Submission Open
Keywords: mental health; burnout; anxiety; occupational stress; women’s mental health; perinatal mental health; healthcare professionals; work-related stress; psychosocial factors; clinical interventions
(This special issue belongs to the Section Mental Health)
Interplay of Motility, Microbiota, and Function: New Insights into GI Disorders, IBS, and SIBO
edited by Tsachi Tsadok Perets
submission deadline 30 Sep 2026 | 1 articles | Viewed by 814 | Submission Open
Keywords: gastrointestinal motility; irritable bowel syndrome (IBS); small intestinal bacterial overgrowth (SIBO); gut microbiota; functional gastrointestinal disorders
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Updates and Advances in Aplastic Anemia and Other Bone Marrow Failures
edited by , Beatrice Drexler and Olaia Naveiras
submission deadline 30 Sep 2026 | Viewed by 461 | Submission Open
Keywords: aplastic anemia; severe aplastic anemia (SAA); bone marrow failures; paroxysmal nocturnal hemoglobinuria (PNH); inherited bone marrow failures
(This special issue belongs to the Section Hematology)
Acute Care Surgery: The Evolution of a Modern Specialty
edited by Mayur Narayan
submission deadline 30 Sep 2026 | Viewed by 333 | Submission Open
Keywords: acute care surgery; emergency surgery; health equity; global surgery; trauma care; surgical workforce; surgical in-novation; decision-making
(This special issue belongs to the Section Emergency Medicine)
Innovative Treatments and Management of Diabetes in Pregnancy
edited by Verónica Perea
submission deadline 30 Sep 2026 | Viewed by 251 | Submission Open
Keywords: diabetes in pregnancy; gestational diabetes mellitus; type 1 diabetes; continuous glucose monitoring; automated insulin delivery; innovative therapies; digital health
(This special issue belongs to the Section Endocrinology & Metabolism)
Update and Emerging Trends in Urological Surgery
edited by Yasmin Abu-Ghanem
submission deadline 30 Sep 2026 | Viewed by 233 | Submission Open
Keywords: urology; urological surgery; precision medicine; biomarkers; minimally invasive surgery; multidisciplinary care
(This special issue belongs to the Section Nephrology & Urology)
Current Concepts in Shoulder Arthroplasty—Degenerative Pathology, Scapular Morphology, Posture and Kinematics, Realignment Procedures, Fracture Reconstruction, and Outcome Measurement submission deadline 1 Oct 2026 | 3 articles | Viewed by 1694 | Submission Open
Keywords: reverse total shoulder arthroplasty; cuff tear arthropathy; osteoarthritis; proximal humeral fracture sequelae; revision; long-term outcome; implant design; biomechanics
(This special issue belongs to the Section Orthopedics)
Clinical Perspectives in Emerging Infectious Diseases submission deadline 4 Oct 2026 | Viewed by 238 | Submission Open
Keywords: emerging infectious diseases; one health; arbovirus disease; avian influenza; hemorrhagic fever; coronavirus diseases; Nipah virus
(This special issue belongs to the Section Infectious Diseases)
Diagnosis and Treatment of Obstetrics and Gynecology Cancers
edited by
submission deadline 5 Oct 2026 | 4 articles | Viewed by 12101 | Submission Open
Keywords: gynecological cancers; endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; vaginal cancer; breast cancer; surgery; radio-therapy; systemic treatment; immunotherapy; sentinel lymph node biopsy; minimally invasive surgery; fertility preservation; gestational trophoblastic disease
(This special issue belongs to the Section Obstetrics & Gynecology)
New Insights into Pediatric Otolaryngology: From Diagnosis to Minimally Invasive Therapies submission deadline 5 Oct 2026 | 3 articles | Viewed by 2288 | Submission Open
Keywords: pediatric otolaryngology; minimally invasive; early diagnosis; olfactory disorders; pediatric rhinology; pediatric airway; pediatric ENT; pediatric sleep disorders; pediatric diagnosis
(This special issue belongs to the Section Clinical Pediatrics)
Thoracic Radiochemoimmunotherapy for Non-Small Cell Lung Cancer (NSCLC): Evolving Techniques and Clinical Applications
edited by
submission deadline 5 Oct 2026 | 1 articles | Viewed by 1292 | Submission Open
Keywords: radiotherapy; radiology; oncology; non-small cell lung cancer; real-world data; immunotherapy; radiation dose escalation
(This special issue belongs to the Section Oncology)
Current Progress and Future Directions in Orthodontics and Periodontology
edited by and
submission deadline 5 Oct 2026 | Viewed by 346 | Submission Open
Keywords: orthodontics; periodontology; interdisciplinary treatment; orthodontic tooth movement; periodontal phenotype; digital dentistry; regenerative therapy; clinical outcomes; treatment planning; future perspectives of interdisciplinarity
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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