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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Updates on Pediatric Neurological Disorders and Neurorehabilitation

edited by

Lidia Perenc

and

Justyna Podgórska-Bednarz

submission deadline 20 Mar 2027 | 2 articles | Viewed by 1814 | Submission Open

Keywords: child neurological disorders; neurorehabilitation; neurogenetics; treatment; quality of life; rehabilitation teams; congenital brain disorders; trauma; movement disorders; cerebral palsy

(This special issue belongs to the Section Clinical Pediatrics)

Perspectives in Bionic Reconstruction and Post-Amputation Management

edited by

Alexander Gardetto

and Jennifer Ernst

submission deadline 20 Mar 2027 | 2 articles | Viewed by 1795 | Submission Open

Keywords: bionic reconstruction; advanced prosthetics; neurorehabilitation; sensory feedback; motor control

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Advances in Lower Limb Trauma and Orthopedic Surgery: From Bench to Bedside

edited by

Se Won Lee

and

Jihyo Hwang

submission deadline 20 Mar 2027 | 3 articles | Viewed by 1788 | Submission Open

Keywords: lower limb trauma; fracture fixation; arthroplasty; biomechanics; orthopaedic surgery; clin-ical outcomes; minimally invasive techniques; rehabilitation

(This special issue belongs to the Section Orthopedics)

Minimally Invasive Spine Surgery: Evidence, Advances and Controversies

edited by

Miltiadis Georgiopoulos

, Constantine Constantoyannis,

Mark A. MacLean

and Oliver Lasry

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1671 | Submission Open

Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality

(This special issue belongs to the Section Clinical Neurology)

Novel Perspectives in Transcatheter Aortic Valve Implantation

edited by Nay Min Htun

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1616 | Submission Open

Keywords: TAVI; life-time management; TAVI-in-TAVI; bicuspid valve; pure aortic regurgitation; small annuli

(This special issue belongs to the Section Cardiology)

Gynecologic Cancers: Current Clinical Management and Multidisciplinary Treatment Strategies

edited by

Iason Psilopatis

and

Christos Damaskos

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1466 | Submission Open

Keywords: gynecologic; cancer; uterus; ovarian; endometrial; cervical

(This special issue belongs to the Section Obstetrics & Gynecology)

Management of Diabetes-Related Cardiovascular Disease: Current Treatment and Future Options

edited by Antonio J. Amor and Tonet Serés-Noriega

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1411 | Submission Open

Keywords: type 1 diabetes; type 2 diabetes; cardiovascular disease; biomarkers; atherosclerosis; cardioprotective drugs; vascular ultrasound

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Outcomes in Lumbar Spinal Stenosis Treatment

edited by Rafał Staszkiewicz and

Beniamin Oskar Grabarek

submission deadline 20 Mar 2027 | 2 articles | Viewed by 1384 | Submission Open

Keywords: lumbar spinal stenosis; clinical outcomes; decompression surgery; conservative management; molecular biomarkers; inflammation and fibrosis; neurotrophic factors; personalized medicine; siganling pathways; quality of life

(This special issue belongs to the Section Orthopedics)

Orthodontics: Current Management and Future Options

edited by Arūnas Vasiliauskas and Aistė Kavaliauskienė

submission deadline 20 Mar 2027 | 2 articles | Viewed by 1338 | Submission Open

Keywords: digital orthodontics; clear aligner therapy; accelerated tooth movement; micro-implants; artificial intelligence; patient-centred outcomes; treatment efficiency

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Perspective of Oral and Maxillo-Facial Surgery: 2nd Edition

edited by

Valentino Vellone

Umberto Committeri

and Alessandra Lucchese

submission deadline 20 Mar 2027 | 2 articles | Viewed by 1204 | Submission Open

Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Current Therapeutic Approaches to Addictive Disorders

edited by Linda Haddad

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1150 | Submission Open

Keywords: addiction treatment; dependence; withdrawal management; relapse prevention; recovery; rehabilitation and support

(This special issue belongs to the Section Mental Health)

Novel Research in Cardiovascular Imaging

edited by Stanciu Silviu and

Lucia Agoston-Coldea

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1148 | Submission Open

Keywords: echocardiography; cardiac CT; CMR; nuclear medicine; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Pulmonary Hypertension and Chronic Lung Disease: Diagnosis and Management

edited by

Josep Montserrat-Capdevila

and

Emmanuel E. Egom

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1068 | Submission Open

Keywords: pulmonary hypertension; chronic obstructive pulmonary disease (COPD); chronic lung disease; epidemiology; exacerbations; comorbidities; risk factors; diabetes; systemic inflammation; real-world data

(This special issue belongs to the Section Respiratory Medicine)

Advances in Interventional Cardiology: From Access to Outcomes

edited by James Cotton and Benjamin Wrigley

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1058 | Submission Open

Keywords: interventional cardiology; acute coronary syndrome; chronic coronary syndrome; TAVI; TAVR; TEER; TMVR; T-TEER; TTVR; service redesign

(This special issue belongs to the Section Cardiology)

Diagnosis and Treatment of Pleura and Lung: Clinical Advances in Intensive Care

edited by

Alen Protić

and

Vlatka Sotosek

submission deadline 20 Mar 2027 | 1 articles | Viewed by 1033 | Submission Open

Keywords: thoracic drainage; lung recruitment; lung ultrasound; pleural effusion; pneumothrax; B-line; lung atelectasis

(This special issue belongs to the Section Intensive Care)

Updates on Reconstructive Urology

edited by

Fabio Campodonico

submission deadline 20 Mar 2027 | 1 articles | Viewed by 978 | Submission Open

Keywords: reconstructive urology; urethral stenosis; urethroplasty; urethral diverticulum; ureteral stenosis; male incontinence; urinary diversion; hypospadias; microsurgery; experimental microsurgery; bladder diverticulum; neobladder

(This special issue belongs to the Section Nephrology & Urology)

Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Advancing Diagnosis and Management

edited by Olga Reitblat

submission deadline 20 Mar 2027 | 2 articles | Viewed by 950 | Submission Open

Keywords: cataract surgery; premium intraocular lenses (IOLs); IOL power calculation; visual outcomes; refractive cataract surgery; multifocal IOL; extended depth of focus (EDOF) IOL; toric IOL; full range; vision IOL; biometry

(This special issue belongs to the Section Ophthalmology)

Rebuilding the Knee: From Repair to Replacement and Recovery

edited by Young-Jin Seo

submission deadline 20 Mar 2027 | 2 articles | Viewed by 895 | Submission Open

Keywords: cartilage; meniscus; total knee arthroplasty; knee surgery; anterior cruciate ligament injuries; posterior cruciate ligament injuries; ligament reconstruction; patellofemoral disorders; osteotomy; sports medicine; rehabilitation; functional recovery

(This special issue belongs to the Section Orthopedics)

New Insights in Trauma and Emergency Surgery

edited by Kai Oliver Jensen and Valentin Neuhaus

submission deadline 20 Mar 2027 | 1 articles | Viewed by 877 | Submission Open

Keywords: trauma and emergency surgery; multiple trauma; orthopedic trauma; surgery; concepts in trauma

(This special issue belongs to the Section Emergency Medicine)

Digital Innovations in Obstetrics and Gynecology: Artificial Intelligence, Diagnostic Advances, Minimally Invasive Surgery, and Clinical Decision-Making

edited by

Iason Psilopatis

submission deadline 20 Mar 2027 | 2 articles | Viewed by 724 | Submission Open

Keywords: obstetrics; gynecology; artificial intelligence; machine learning; minimally invasive surgery; digital health

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)

Colorectal Surgery: Advances in Modern Clinical Management

edited by

Algimantas A. Tamelis

submission deadline 20 Mar 2027 | 1 articles | Viewed by 659 | Submission Open

Keywords: colorectal cancer management; surgery; complications; organ preservation; screening; colonic diverticular disease; colonic diverticulitis; hemorrhoids

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Thyroid Cancer: Diagnosis, Surgical Treatment and Postoperative Radioactive Iodine Therapy: 2nd Edition

edited by Alfred A. Simental

submission deadline 20 Mar 2027 | 1 articles | Viewed by 648 | Submission Open

Keywords: thyroid nodule; thyroid ultrasound; radiofrequency ablation; molecular analysis; thyroid surgery

(This special issue belongs to the Section Oncology)

Hemophilia: Current Trends and Future Directions: 2nd Edition

edited by

Jonathan C. Roberts

and

Michael B. Nichol

submission deadline 20 Mar 2027 | 1 articles | Viewed by 638 | Submission Open

Keywords: hemophilia; prophylaxis; gene therapy; burden of illness; quality of life; patient reported outcomes; hemarthrosis; women and hemophilia

(This special issue belongs to the Section Hematology)

New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches

edited by Gabriella Teresa Capolupo

submission deadline 20 Mar 2027 | Viewed by 509 | Submission Open

Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Challenges and Innovation in Trauma and Acute Care Surgery

edited by Michel Teuben

submission deadline 20 Mar 2027 | Viewed by 463 | Submission Open

Keywords: traumatology; trauma surgery; acute care surgery; femur; injury

(This special issue belongs to the Section Emergency Medicine)

Atrial Fibrillation: Contemporary Evidence from Prevention to Catheter Ablation

edited by

Bogdan Enache

, Radu Gabriel Vătăşescu and

Dragos Cozma

submission deadline 20 Mar 2027 | 1 articles | Viewed by 401 | Submission Open

Keywords: atrial fibrillation; prevention; risk-factor modification; screening; rhythm control; catheter ablation; stroke prevention; outcomes

(This special issue belongs to the Section Cardiology)

Exploring Diagnostic and Therapeutic Advances in Neurodegenerative Disorders

edited by

Stefania Kalampokini

and

Effrosyni Koutsouraki

submission deadline 20 Mar 2027 | Viewed by 382 | Submission Open

Keywords: neurodegenerative disease; Parkinson’s disease; Alzheimer’s disease; Friedreich’s ataxia; Huntington’s disease; Lewy body dementia; dementia; immunosenescence; inflammaging

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates on Anesthesia and Perioperative Medicine

edited by Béla Fülesdi and

Sorin J. Brull

submission deadline 20 Mar 2027 | Viewed by 371 | Submission Open

Keywords: anesthesia; perioperative complications; residual neuromuscular block; postoperative pulmonary complications; intensive care unit acquired weakness; intensive care medicine; airway management; patient safety

(This special issue belongs to the Section Anesthesiology)

Clinical Recent Advances in the Surgical Treatment of Heart Valve Disease

edited by

Beatrice Bacchi

and Aleksander Dokollari

submission deadline 20 Mar 2027 | Viewed by 370 | Submission Open

Keywords: heart valve surgery; prosthetic valves; intervention surgery; minimally invasive and robotic surgery; valve repair and replacement

(This special issue belongs to the Section Cardiology)

Pediatric Orthopedics: Diagnosis, Treatment, and Comprehensive Management

edited by Michał Latalski and

Erich Rutz

submission deadline 20 Mar 2027 | 1 articles | Viewed by 369 | Submission Open

Keywords: pediatric orthopedics; cerebral palsy; SMA; spinal deformities; developmental dysplasia of the hip; clubfoot; neuro-orthopedics; gait analysis; pediatric traumatology; skeletal dysplasia; biomechanics; congenital musculoskeletal anomalies

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Pediatric Hepatobiliary Surgery

edited by Ioannis A. Ziogas

submission deadline 20 Mar 2027 | Viewed by 351 | Submission Open

Keywords: pediatric hepatobiliary surgery; pediatric transplantation; pediatric surgery; liver transplantation; biliary atresia; choledochal cyst; liver cancer

(This special issue belongs to the Section Clinical Pediatrics)

Gastroparesis: Emerging Insights and Endoscopic Therapeutic Strategies

edited by Sabrina Testoni

submission deadline 20 Mar 2027 | Viewed by 350 | Submission Open

Keywords: gastroparesis; gastric dismotility; gastric emptying; gastric per-oral miotomy; pyloromyotomy; gastric electric stim-ulation; botulinum toxin

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Clinical Insight: From Open Surgery to Minimally Invasive Foot and Ankle Surgery

edited by Enrique A. Testa and Daniel Poggio

submission deadline 20 Mar 2027 | Viewed by 349 | Submission Open

Keywords: minimally invasive surgery; foot surgery; ankle surgery; trauma surgery; orthopedic surgery; ankle arthroscopy

(This special issue belongs to the Section Orthopedics)

Neuroimmunology in Neurological Disorders: Clinical Diagnosis and Treatment

edited by Charalampos Skarlis,

Maria Anagnostouli

and

Evangelia Liouta

submission deadline 20 Mar 2027 | Viewed by 343 | Submission Open

Keywords: neuroimmunology; neuroinflammation; neurodegenerative diseases; Parkinson’s disease; multiple sclerosis; CNS autoimmune disease; biomarkers; immunomodulatory therapy

(This special issue belongs to the Section Clinical Neurology)

Colorectal Surgery: Current Concept and Emerging Trends

edited by

Valentin Calu

submission deadline 20 Mar 2027 | Viewed by 332 | Submission Open

Keywords: colorectal surgery; robotic surgery; neoadjuvant treatment; minimally invasive techniques; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Optimizing Outcomes in Pancreato-Biliary Care: Integrating Technology, Technique, and Personalized Approaches

edited by

Andrea Tufo

submission deadline 20 Mar 2027 | Viewed by 318 | Submission Open

Keywords: pancreato-biliary care; pancreatic diseases; biliary diseases; hepato-pancreato-biliary (HPB) surgery; interventional endoscopy; interventional radiology; minimally invasive surgery; EUS-guided procedures; ERCP; personalized care/personalized medicine; multidisciplinary care; clinical outcomes; robotics and AI in PB care

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Contactless Magnetocardiography and Related Novel Methods for Non-Invasive Experimental and Clinical Functional Imaging of Normal and Abnormal Cardiac Electrophysiology

edited by

Riccardo Fenici

Donatella Brisinda

and

Peter Fenici

submission deadline 20 Mar 2027 | Viewed by 260 | Submission Open

Keywords: magnetocardiography; non-invasive functional imaging of cardiac electrophysiology; arrhythmogenic mechanisms; atrial fibrillation; magnetoionography; antiarrhythmic drugs; artificial intelligence

(This special issue belongs to the Section Cardiology)

Head and Neck Surgery: Immunotherapy’s Role in Shaping Treatment Paradigms

edited by

Mark S. Swanson

submission deadline 20 Mar 2027 | Viewed by 256 | Submission Open

Keywords: head and neck surgery; otorhinolaryngology; ENT; transoral surgery; laryngeal surgery; laryngeal carcinoma; sinonasal surgery; oral cancer; oropharyngeal cancer; laryngectomy; immunotherapy; head and neck cancer; cutaneous cancer

(This special issue belongs to the Section Otolaryngology)

Game-Changing Advances in Minimally Invasive Spine Surgery

edited by Rouzbeh Motiei-Langroudi

submission deadline 20 Mar 2027 | Viewed by 245 | Submission Open

Keywords: minimally invasive spine surgery (MISS); technological innovation; navigation systems/robotic-assisted; endoscopic techniques; artificial intelligence/machine learning

(This special issue belongs to the Section Clinical Neurology)

Advances in Mental Health: All Ages and Multidisciplinary Clinical Perspectives

edited by Clara González-Sanguino and

Jairo Rodríguez-Medina

submission deadline 20 Mar 2027 | Viewed by 192 | Submission Open

Keywords: stigma; discrimination; mental health; clinical psychology; depression and anxiety

(This special issue belongs to the Section Mental Health)

Clinical Advances in Extracorporeal Membrane Oxygenation (ECMO)—Second Edition

edited by

Sung-Min Cho

and

Akram Zaaqoq

submission deadline 20 Mar 2027 | Viewed by 149 | Submission Open

Keywords: extracorporeal membrane oxygenation; ECMO; multi-organ failure; outcomes; V-A ECMO; ECPR; V-V ECMO; translational research; clinical research

(This special issue belongs to the Section Intensive Care)

Psychosis Across Disciplines: Emerging Perspectives in Neuroscience, Psychiatry, and Therapy

edited by Inmaculada Peñuelas-Calvo, Roberto Rodríguez-Jiménez and

Lorena García-Fernández

submission deadline 20 Mar 2027 | Viewed by 143 | Submission Open

Keywords: psychosis; lifespan; neuroimaging; psychotherapy; prevention

(This special issue belongs to the Section Mental Health)

Advancing Precision Care in Neuropathic Pain: From Biomarkers to Neuromodulation to Artificial Intelligence

edited by Saurabh Kataria and

Jeremiah Hilkiah Wijaya

submission deadline 20 Mar 2027 | Viewed by 137 | Submission Open

Keywords: neuropathic pain; precision medicine; neuromodulation; spinal cord stimulation; peripheral nerve stimulation; ul-trasound-guided interventions; pain phenotyping; personalized therapeutics; opioid alternatives

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates in Type 2 Diabetes and Related Complications

edited by

Ilias Migdalis

submission deadline 20 Mar 2027 | Viewed by 135 | Submission Open

Keywords: type 2 diabetes; chronic complications; microvascular disease; macrovascular disease; treatment

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Physical Therapy: Current Advances and Future Challenges

edited by

Andreas Brandl

and

Robert Schleip

submission deadline 20 Mar 2027 | Viewed by 132 | Submission Open

Keywords: clinical physical therapy; chronic musculoskeletal disorders; chronic pain management; manual therapy; mind–body medicine; biopsychosocial model; autoimmune diseases; fatigue syndromes; bottom-up and top-down regulation; neurophysiological mechanisms

(This special issue belongs to the Section Clinical Rehabilitation)

Recent Advances in Clinical Perspectives on the Diagnosis and Treatment of Endometriosis

edited by Paweł Basta and

Krzysztof Gałczyński

submission deadline 20 Mar 2027 | Viewed by 126 | Submission Open

Keywords: endometriosis; deep endometriosis; endometrioma; infertility; laparoscopy; minimally invasive techniques; biomarkers; pain; pelvic pain; adenomyosis; adhesions; dysmenorrhea; dyspareunia

(This special issue belongs to the Section Obstetrics & Gynecology)

Therapies for Heart Failure: Clinical Updates and Perspectives: 2nd Edition

edited by Cristina Tudoran, Stela Iurciuc and

Dragos Cozma

submission deadline 20 Mar 2027 | Viewed by 118 | Submission Open

Keywords: mechanisms of heart failure; new therapies for heart failure; chronic and acute heart failure; new approaches to managing heart failure patients; special populations; clinical outcome

(This special issue belongs to the Section Cardiology)

The State of the Art in Robotic Thoracic Surgery: Innovation, Complexity and Outcomes

edited by Michael Zervos

submission deadline 20 Mar 2027 | Viewed by 115 | Submission Open

Keywords: thoracic surgery; robotic surgery; single-port robotic surgery; robotic-assisted thoracic surgery; minimally invasive surgery; lung cancer

(This special issue belongs to the Section General Surgery)

Clinical Challenges and Advances in Hepatobiliary and Pancreatic Surgery

edited by

Marco Massani

and

Alessandro Veltri

submission deadline 20 Mar 2027 | Viewed by 115 | Submission Open

Keywords: pancreatic cancer; pancreatic cancer surgery; neoadjuvant chemotherapy; perioperative management; surgical approaches

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Gastrointestinal Surgery: New Insights into Tumor Metabolism and Translational Oncology

edited by Konstantinos Romanidis

submission deadline 20 Mar 2027 | Viewed by 110 | Submission Open

Keywords: gastrointestinal cancer; tumor metabolism; translational oncology; surgical oncology; metabolic profiling; artificial intelligence

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 1151-1200 on page 24 of 30.

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