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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cardiovascular Risk in COVID-19 Survivors: From Emergency Department Management to Cardiovascular Rehabilitation
edited by and Stela Iurciuc
submission deadline 28 Mar 2027 | Viewed by 188 | Submission Open
Keywords: cardiovascular risk management; COVID-19 survivors; long COVID syndrome; post-acute sequelae of SARS-CoV-2 infection (PASC); emergency department; cardiovascular rehabilitation; risk stratification; integrated care
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Diagnosis and Treatment Strategies in Sjogren's Disease (SjD)
edited by , and Nancy McNamara
submission deadline 29 Mar 2027 | Viewed by 527 | Submission Open
Keywords: Sjogren; Sjogren’s disease; lymphocytic tissue infiltration; interdisciplinary care; pathogenesis; caries; corneal erosions; autoimmunity; lymphoproliferative (or lymphoma)
(This special issue belongs to the Section Immunology & Rheumatology)
Approaches to Prevention and Management of Postoperative Complications in Minimally Invasive Surgery
edited by Shingo Tsujinaka
submission deadline 30 Mar 2027 | 4 articles | Viewed by 3012 | Submission Open
Keywords: minimally invasive surgery; postoperative complications; preventive measures; risk assessment; surgical techniques; patient optimization; complication management; surgical outcomes; patient satisfaction; patient-reported outcomes
(This special issue belongs to the Section General Surgery)
Clinical and Laboratory Applications of Artificial Intelligence in Haematology
edited by and Bingwen Eugene Fan
submission deadline 30 Mar 2027 | 1 articles | Viewed by 1241 | Submission Open
Keywords: hematology; artificial intelligence/AI; machine learning/ML; innovation; hemostasis; thrombosis; diagnostics; prog-nosis; laboratory automation; clinical decision support; precision medicine; big data; digital pathology
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)
The Wide World of Antinuclear Antibodies (ANA)-Associated Disorders: Patterns, Clinical Phenotypes, Comorbidities, and Impact submission deadline 31 Mar 2027 | 1 articles | Viewed by 1909 | Submission Open
Keywords: antinuclear antibodies (ANA); ANA-associated disorders; clinical phenotypes; ANA patterns; lupus, Sjögren’s disease, systemic sclerosis, idiopathic inflammatory myopathies, comorbidities; connective tissue diseases; overlap syndromes; undifferentiated connective tissue disease; risk stratification; patient-centered management
(This special issue belongs to the Section Immunology & Rheumatology)
Aortic Surgery—Back to the Roots and Looking to the Future
edited by Ezin Deniz and
submission deadline 31 Mar 2027 | 1 articles | Viewed by 1374 | Submission Open
Keywords: aortic surgery; hybrid and endovascular innovations; perioperative management; cerebral and organ protection; biomaterials; translational cardiovascular research; imaging in aortic disease; long-term outcomes; cardiovascular surgery
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Cutaneous and Systemic Lupus Erythematosus: Diagnosis, Treatment, and Comorbidities
edited by Magdalena Spałkowska and Joanna Kosałka-Węgiel
submission deadline 31 Mar 2027 | 1 articles | Viewed by 637 | Submission Open
Keywords: systemic lupus erythematosus; cardiovascular; Raynaud’s; cutaneous lupus erythematosus; autoimmune diseases
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Applications and Advances in Arthroscopic, Endoscopic, and Minimally Invasive Techniques in Orthopaedics
edited by Stylianos Kapetanakis
submission deadline 31 Mar 2027 | 1 articles | Viewed by 479 | Submission Open
Keywords: arthroscopy; endoscopic surgery; minimally invasive surgery; orthopaedic surgery; sports medicine; spine surgery; surgery; robotics
(This special issue belongs to the Section Orthopedics)
Interventional Cardiology: Evolving Evidence and Emerging Horizons
edited by
submission deadline 31 Mar 2027 | Viewed by 366 | Submission Open
Keywords: coronary artery disease; percutaneous coronary intervention; drug-coated balloon; intravascular imaging; fractional flow reserve; transcatheter aortic valve implantation; transcatheter mitral valve repair; clinical outcomes
(This special issue belongs to the Section Cardiology)
Clinical Advances in Coronary Artery Bypass Grafting
edited by and Mirko Doss
submission deadline 31 Mar 2027 | Viewed by 256 | Submission Open
Keywords: coronary artery bypass grafting; CABG; myocardial revascularization; multiarterial grafting; conduit selection; off-pump CABG; on-pump CABG; anaortic CABG; no-touch technique; minimally invasive coronary surgery; endo-scopic coronary surgery; robot-assisted coronary surgery; hybrid coronary revascularization; graft patency; perioper-ative outcomes; cardiac surgery; cardiovascular innovation
(This special issue belongs to the Section Cardiovascular Medicine)
JSOPB 2025–2026 Congress Special Issue—Update on Organ Preservation and Transplantation submission deadline 31 Mar 2027 | Viewed by 219 | Submission Open
Keywords: organ preservation; transplantation; pharmacology; clinical engineering; stem cell therapy
(This special issue belongs to the Section General Surgery)
Clinical Updates on Pediatric Gastrointestinal and Nutritional Disorders submission deadline 3 Apr 2027 | Viewed by 168 | Submission Open
Keywords: gastrointestinal; malnutrition; obesity; nutrition; pancreas; cystic fibrosis; epidemiology; eosinophilic esophagitis; liver disorders; endoscopy
(This special issue belongs to the Section Clinical Pediatrics)
Optimizing Colorectal Cancer Therapy
edited by Fernando Mendoza-Moreno
submission deadline 4 Apr 2027 | Viewed by 52 | Submission Open
Keywords: rectal cancer; colorectal surgery; neoadjuvant chemoradiotherapy; TNM staging; tumor deposits; minimally invasive surgery; multidisciplinary oncologic care
(This special issue belongs to the Section Oncology)
Clinical Research and Perspectives in Hepatobiliary Surgery and Liver Transplant submission deadline 4 Apr 2027 | Viewed by 35 | Submission Open
Keywords: hepatobiliary surgery; liver transplantation; hepatopancreatobiliary surgery; transplant oncology; machine perfusion; organ preservation; donation after circulatory death; extended-criteria donors; living donor liver transplantation; minimally invasive surgery; robotic surgery; hepatocellular carcinoma; cholangiocarcinoma; colorectal liver metastases; perioperative outcomes; patient-reported outcomes; precision medicine
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Exercise, Injury and Rehabilitation: Integrated Perspectives in Sports Medicine submission deadline 5 Apr 2027 | 6 articles | Viewed by 16351 | Submission Open
Keywords: sports medicine; biomechanics; injury prevention; exercise physiology; sports performance; load management; exercise prescription; return to play; recovery
(This special issue belongs to the Section Sports Medicine)
Emerging Therapeutic Strategies for Coronary and Structural Heart Disease
edited by
submission deadline 5 Apr 2027 | Viewed by 131 | Submission Open
Keywords: coronary artery disease; structural heart disease; transcatheter interventions; percutaneous coronary intervention; valvular heart disease; cardiovascular therapeutics; interventional cardiology
(This special issue belongs to the Section Cardiovascular Medicine)
Blood Pressure Disorders: Risk Assessment, Surveillance and Clinical Interventions
edited by
submission deadline 7 Apr 2027 | Viewed by 305 | Submission Open
Keywords: hypertension; secondary hypertension; hypotension; target organ damage; hypertension phenotypes; hypertension emergency; hypertension urgency; microangiopathy; macroangiopathy; endothelial dysfunction; hypovolaemia; cardiogenic shock; dysautonomia
(This special issue belongs to the Section Cardiovascular Medicine)
Management of Congenital Heart Disease (CHD)
edited by Sarah Nordmeyer and Marie Schafstedde
submission deadline 10 Apr 2027 | 6 articles | Viewed by 6079 | Submission Open
Keywords: congenital heart disease; imaging; diagnostics; surgical innovations; minimally invasive interventions
(This special issue belongs to the Section Cardiovascular Medicine)
Sports Cardiology: Current Clinical Status and Outlook into the Future
edited by Aakash Bavishi and Matthew W Martinez
submission deadline 10 Apr 2027 | 2 articles | Viewed by 2155 | Submission Open
Keywords: sports cardiology; athletes; cardiac imaging; hypertrophic cardiomyopathy; screening; electrocardiogram; electrophysiology; echocardiography; sudden cardiac death
(This special issue belongs to the Section Cardiology)
New Insights into Glaucoma: 2nd Edition
edited by and
submission deadline 10 Apr 2027 | 2 articles | Viewed by 2080 | Submission Open
Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)
(This special issue belongs to the Section Ophthalmology)
Clinical Advances in Cardiothoracic Anesthesiology
edited by
submission deadline 10 Apr 2027 | 3 articles | Viewed by 2025 | Submission Open
Keywords: cardiac anesthesiology; thoracic anesthesiology; precision medicine; prevention of organ dysfunction; mechanical circulatory support; minimally invasive surgery
(This special issue belongs to the Section Anesthesiology)
Current Challenges and Perspectives in Aortic Valve Replacement
edited by , Quentin Fischer and David Del Val
submission deadline 10 Apr 2027 | 1 articles | Viewed by 1659 | Submission Open
Keywords: aortic valve replacement; transcatheter aortic valve implantation (TAVI); surgical aortic valve replacement; prosthesis–patient mismatch; structural heart disease; heart team; valve durability; coronary access; valve-in-valve
(This special issue belongs to the Section Cardiovascular Medicine)
Crohn’s Disease: Ongoing Challenges and Future Directions in Diagnosis and Monitoring
edited by Laura Maria Minordi and
submission deadline 10 Apr 2027 | Viewed by 110 | Submission Open
Keywords: Crohn’s disease; imaging; endoscopy; complications; advanced therapies; radiomic; surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Functional Diagnostics and Physiotherapy of Musculoskeletal Disorders submission deadline 10 Apr 2027 | Viewed by 89 | Submission Open
Keywords: functional diagnostics; physiotherapy; rehabilitation; musculoskeletal system; functional assessment; gait analysis; movement biomechanics; postural control; postural stability; muscle strength; muscle tone; digital technologies in rehabilitation; objective measurement methods
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Swallowing Disorders: Advancing Measurement Science in Dysphagia
edited by Phoebe Macrae
submission deadline 10 Apr 2027 | Viewed by 36 | Submission Open
Keywords: dysphagia; measurement science; outcome measurement; psychometrics; swallowing physiology; instrumental assessment; quantitative measurement; measurement methodology; biomarkers; patient-reported outcome measures (PROMs); artificial intelligence
(This special issue belongs to the Section Otolaryngology)
Advances in Musculoskeletal Rehabilitation and Functional Movement
edited by
submission deadline 13 Apr 2027 | 5 articles | Viewed by 5775 | Submission Open
Keywords: corrective exercise; functional training; biomechanics; resistance training; movement impairment; electromyography; muscle activation; musculoskeletal rehabilitation
(This special issue belongs to the Section Clinical Rehabilitation)
Hypertension and Cardiovascular Disease: Clinical Updates and Perspectives: 2nd Edition
edited by and Nicola Virtuoso
submission deadline 15 Apr 2027 | 7 articles | Viewed by 5723 | Submission Open
Keywords: hypertension management; cardiovascular risk assessment; novel antihypertensive therapies; hypertension in pregnancy; hypertensive emergencies; cardiovascular disease prevention; pharmacological interventions for cardiovascular disease
(This special issue belongs to the Section Cardiovascular Medicine)
New Perspectives and Innovations in Critical Illness submission deadline 15 Apr 2027 | 3 articles | Viewed by 2266 | Submission Open
Keywords: critical illness; intensive care; ECMO; hemodynamic management; shock physiology; cardiovascular support
(This special issue belongs to the Section Intensive Care)
Future-Proof Care for Patients with Kidney Stones
edited by and Oliver Wiseman
submission deadline 15 Apr 2027 | 2 articles | Viewed by 1160 | Submission Open
Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life
(This special issue belongs to the Section Nephrology & Urology)
Retinal Diseases: Recent Advances in Diagnosis and Treatment—2nd Edition
edited by Dario Giorgio and Dario Pasquale Mucciolo
submission deadline 15 Apr 2027 | 1 articles | Viewed by 776 | Submission Open
Keywords: retinal diseases; retinal degeneration; macular degeneration; OCT; retinal imaging
(This special issue belongs to the Section Ophthalmology)
Clinical Updates on Reproductive Endocrinology in Children and Adolescents submission deadline 15 Apr 2027 | Viewed by 445 | Submission Open
Keywords: reproductive endocrinology; adolescents; male hypogonadism; female hypogonadism; reproductive metabolism; PCOS; POF; receptor abnormalities; menstrual cycle; transgender health; CAH; ovaries; gonads; hormones; sex development; amenorrhea; estrogen resistance; androgen resistance; teen pregnancy; oncology; preservation of fertility
(This special issue belongs to the Section Clinical Pediatrics)
Advances in Retinal Diseases—Mechanisms, Diagnostics, and Emerging Therapies, 2nd Edition
edited by
submission deadline 15 Apr 2027 | 1 articles | Viewed by 410 | Submission Open
Keywords: inherited retinal diseases; age-related macular degeneration; diabetic retinopathy; multimodal retinal imaging; treatment
(This special issue belongs to the Section Ophthalmology)
Revisional and Conversion Bariatric Surgery: Safety and Outcomes
edited by Jerry Dang and Thomas H. Shin
submission deadline 15 Apr 2027 | Viewed by 283 | Submission Open
Keywords: revisional bariatric surgery; conversion surgery; weight recurrence; surgical outcomes; sleeve gastrectomy; roux-en-y gastric bypass; post-bariatric complications; GERD
(This special issue belongs to the Section General Surgery)
Gene Correction and Regenerative Therapies for Inherited Retinal Diseases: Clinical Perspectives
edited by Sushma Kalmodia
submission deadline 15 Apr 2027 | Viewed by 273 | Submission Open
Keywords: gene therapy; AAV; IRD; retinal organoids; RPE
(This special issue belongs to the Section Ophthalmology)
Contemporary Advances in Cardiomyopathies: Diagnosis, Risk Assessment and Therapeutic Innovation
edited by Maria Cristina Carella and
submission deadline 15 Apr 2027 | Viewed by 131 | Submission Open
Keywords: cardiomyopathies; cardiovascular genetics; cardiac magnetic resonance; advanced cardiovascular imaging; heart failure; sports cardiology; precision medicine
(This special issue belongs to the Section Cardiology)
The Role of Non-Radiological Imaging in Interventional Arrhythmology Procedures: Challenges and New Perspectives
edited by and Stefano Bandino
submission deadline 15 Apr 2027 | Viewed by 102 | Submission Open
Keywords: cardiac interventional arrhythmology; cardiac ultrasound; echocardiography; near-zero x-ray; electroanatomical mapping; intracardiac echocardiography; thoracic ultrasound
(This special issue belongs to the Section Cardiology)
Sports Injury Rehabilitation and Clinical Recovery Strategies submission deadline 15 Apr 2027 | Viewed by 90 | Submission Open
Keywords: sports injury; rehabilitation; recovery; return to sport; return to performance; mechanobiology; load management; neuromuscular control; digital health; injury prevention
(This special issue belongs to the Section Sports Medicine)
Biomarkers in Cancer Diagnosis and Prognosis
edited by Gina Gheorghe
submission deadline 15 Apr 2027 | Viewed by 83 | Submission Open
Keywords: cancer biomarkers; cancer diagnosis; cancer prognosis; liquid biopsy; precision oncology; tumor microenvironment; treatment response; personalized medicine
(This special issue belongs to the Section Oncology)
Cardiac Arrest: From Prevention to Survivorship—Advancing the Chainmail of Survival submission deadline 16 Apr 2027 | Viewed by 221 | Submission Open
Keywords: cardiac arrest; cardiopulmonary resuscitation (CPR); emergency medicine; emergency department; critical care; basic life support (BLS); advanced life support (ALS); chain of survival; chainmail of survival
(This special issue belongs to the Section Emergency Medicine)
Challenges in Diagnosis and Treatment of Infertility—2nd Edition
edited by Konstantinos A. Zikopoulos
submission deadline 20 Apr 2027 | 6 articles | Viewed by 28228 | Submission Open
Keywords: fertility; regeneration; age-related infertility; preimplantation diagnosis; precision assessment; individualized fertility needs; clinical diagnosis; in vitro fertilization
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Pancreatic Disorder, Pancreatitis, and Pancreatic Cancer: Interconnections, Clinical Challenges, and Therapeutic Advances submission deadline 20 Apr 2027 | 3 articles | Viewed by 10007 | Submission Open
Keywords: pancreatic disorder; pancreatitis; pancreatic cancer; translational research; diagnosis; treatment
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Kidney Transplantation: State-of-the-Art Knowledge
edited by , Georgios Geropoulos and Kyriakos Psarras
submission deadline 20 Apr 2027 | 3 articles | Viewed by 5749 | Submission Open
Keywords: kidney transplantation; end-stage renal disease; immunosuppression; organ donation; graft survival; graft rejection
(This special issue belongs to the Section Nephrology & Urology)
Sepsis and Septic Shock: Diagnosis, Treatment, and Prognosis
edited by Luigi Carbone and Daniela Pugliese
submission deadline 20 Apr 2027 | 6 articles | Viewed by 5007 | Submission Open
Keywords: sepsis; septic shock; diagnosis and screening tools; risk stratification; machine learning; advanced therapies
(This special issue belongs to the Section Intensive Care)
New Clinical Advances in Chronic Asthma—2nd Edition
edited by Vitaliano Nicola Quaranta
submission deadline 20 Apr 2027 | 4 articles | Viewed by 4579 | Submission Open
Keywords: chronic asthma; breathlessness; coughing; inhaled corticosteroids (ICS); long-acting beta-agonists (LABAs); personalized treatment; chronic rhinosinusitis; nasal polyps; bronchiectasis; endotypes; oral corticosteroids
(This special issue belongs to the Section Respiratory Medicine)
Hidradenitis Suppurativa: Clinical Diagnosis, Treatment, and Management
edited by Piotr K. Krajewski
submission deadline 20 Apr 2027 | 5 articles | Viewed by 4516 | Submission Open
Keywords: hidradenitis suppurativa; acne inversa; clinical diagnosis; disease severity assessment; biologic therapy; surgical management; comorbidities; quality of life; multidisciplinary care; real world evidence
(This special issue belongs to the Section Dermatology)
Non-Pharmacological Therapies and Exercise Interventions in Clinical Populations submission deadline 20 Apr 2027 | 4 articles | Viewed by 4341 | Submission Open
Keywords: non-pharmacological interventions; physiotherapy approaches; physical activity; acute and chronic diseases; acute and chronic pain
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Outcomes of Glaucoma Surgery: Visual Acuity, Effectiveness and Quality of Life submission deadline 20 Apr 2027 | 6 articles | Viewed by 3930 | Submission Open
Keywords: glaucoma surgery; visual acuity; intraocular pressure; surgical outcomes; trabeculectomy; microinvasive glaucoma surgery; postoperative complications; functional vision
(This special issue belongs to the Section Ophthalmology)
Infectious Diseases and Host Responses: Clinical, Immunological, and Outcome-Orientated Perspectives
edited by
submission deadline 20 Apr 2027 | 3 articles | Viewed by 3695 | Submission Open
Keywords: microbiology; infection; resistance; epidemiology; microbiome; prevention; therapy
(This special issue belongs to the Section Infectious Diseases)
Anesthesia and Intensive Care: Clinical Practices and Prospects
edited by
submission deadline 20 Apr 2027 | 4 articles | Viewed by 3622 | Submission Open
Keywords: artificial intelligence; clinical decision support; perioperative risk stratification; perioperative patient safety; hemodynamic optimization
(This special issue belongs to the Section Intensive Care)
Clinical Therapeutic Advances of Mitral Regurgitation
edited by Angelo Squeri
submission deadline 20 Apr 2027 | 4 articles | Viewed by 3456 | Submission Open
Keywords: mitral regurgitation; mitral valve prolapse; cardiovascular interventions; heart surgery; echocardiography; mag-netic resonance imaging; computed tomography
(This special issue belongs to the Section Cardiovascular Medicine)
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