Journal of Clinical Medicine

Male Fertility in the Modern Age: Challenges and Opportunities

edited by

Angelo Marino

submission deadline 25 Jan 2026 | 2 articles | Viewed by 11864 | Submission Open

Keywords: male infertility; semen parameters; sperm selection; IVF/ICSI

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Keratoconus: Current Status and Prospects

edited by

Uxía Regueiro

and Isabel Lema

submission deadline 25 Jan 2026 | 3 articles | Viewed by 9800 | Submission Open

Keywords: keratoconus; prevention; diagnostic; biomarker discovery; genetics; exposome; treatment; personalized medicine; major challenges; technological advances

(This special issue belongs to the Section Ophthalmology)

Prevention, Diagnosis and Treatment of Oral Mucosal Diseases

edited by

Masanobu Abe

submission deadline 25 Jan 2026 | 3 articles | Viewed by 9531 | Submission Open

Keywords: oral mucosal diseases; oral mucositis; oral precancerous lesions; oral cancer; oral potentially malignant disorders; OPMDs; oral leukoplakia

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Interventional Cardiology—Challenges and Solutions

edited by

Yonggu Lee

submission deadline 25 Jan 2026 | 3 articles | Viewed by 4352 | Submission Open

Keywords: chronic total occlusion; highly calcified coronary or lower extremity arteries; stentless percutaneous coronary intervention; chronic limb threatening ischemia; instent restenosis in the extremity artery diseases; endovascular therapy for pulmonary thromboembolism; transcatheter aortic valve replacemment for the bicuspid aortic valve; transcatheter aortic valve replacement for the valve-in-valve procedure; endovascular therapy for tricospid valve regurgitation; transcatheter edge-to-edge repair for mitral valve regurgitation

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Advances in Treatment for Venous Thromboembolism

edited by

Elisavet Grouzi

and Georgia Kaiafa

submission deadline 25 Jan 2026 | 3 articles | Viewed by 4320 | Submission Open

Keywords: venous thromboembolism; anticoagulation; cancer-associated thrombosis; thrombosis in MPNs; thrombosis in multiple myeloma; antiphospholipidic syndrome; thrombosis in PNH; thrombosis in hemoglobinopathies; thrombophilia; pregnancy and thrombophilia; reversal of anticoagulants; thromboprophylaxis

(This special issue belongs to the Section Hematology)

Foot and Ankle Surgery: Current Advances and Prospects

edited by

Jaeho Cho

submission deadline 25 Jan 2026 | 4 articles | Viewed by 4316 | Submission Open

Keywords: foot and ankle surgery; foot pathologies; ankle disease and trauma; diabetic foot; epidemiology; clinical anatomy; foot orthoses; weight-bearing CT

(This special issue belongs to the Section Orthopedics)

Autism Spectrum Disorder: Diagnosis, Treatment, and Management

edited by

Marios Adamou

submission deadline 25 Jan 2026 | 1 articles | Viewed by 3937 | Submission Open

Keywords: adult autism (including autism spectrum disorders); neurodevelopmental disorders; clinical diagnostics; digital diagnostics; artificial intelligence; multimodal treatments

(This special issue belongs to the Section Mental Health)

Clinical Updates in Cardiac Electrophysiology: 2nd Edition

edited by Kenneth C. Bilchick

submission deadline 25 Jan 2026 | 1 articles | Viewed by 3196 | Submission Open

Keywords: arrhythmias; atrial fibrillation; cardiac electrophysiology; heart rhythm disorders; ablation; ventricular tachycardia; remote monitoring; digital health; artificial intelligence; cardiac magnetic resonance

(This special issue belongs to the Section Cardiology)

Clinical Diagnostic and Therapeutic Approaches in Cardiac Amyloidosis

edited by Grigorios Giamouzis

submission deadline 25 Jan 2026 | 1 articles | Viewed by 3037 | Submission Open

Keywords: cardiac amyloidosis; transthyretin amyloidosis; hypertrophic cardiomyopathy; cardiac imaging; heart failure

(This special issue belongs to the Section Cardiology)

Inflammatory Bowel Diseases: Clinical Advances and Emerging Therapies

edited by

Ewa Malecka-Wojciesko

submission deadline 25 Jan 2026 | 2 articles | Viewed by 2785 | Submission Open

Keywords: inflammatory bowel disease (IBD); ulcerative colitis; Crohn’ s disease; gut inflammation; bowel perforation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advancements in Individualized Plastic and Reconstructive Surgery: Second Edition

edited by

Paul Immanuel Heidekrueger

, Peter Niclas Broer and Denis C. Ehrl

submission deadline 25 Jan 2026 | 2 articles | Viewed by 1588 | Submission Open

Keywords: patient-specific reconstructive procedures; microsurgical precision techniques; autologous tissue transplantation; digital imaging and customization; biomaterials in reconstructive surgery; tissue engineering for plastic reconstruction; flap surgery innovations; personalized cleft surgery; personalized aesthetic surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Ocular Surface Disease: Epidemiology, Diagnosis and Management

edited by

Sandeep K. Dhallu

and

Nicole Carnt

submission deadline 25 Jan 2026 | Viewed by 917 | Submission Open

Keywords: dry eye disease; risk factors; ocular surface disease; inflammatory biomarkers; anterior segment imaging; emerging therapies

(This special issue belongs to the Section Ophthalmology)

Shoulder and Elbow Surgery: Clinical Updates and Perspectives

edited by Taku Hatta, Akihiko Hasegawa and Takuma Yuri

submission deadline 25 Jan 2026 | 1 articles | Viewed by 675 | Submission Open

Keywords: rotator cuff injuries; shoulder arthroplasty; elbow surgery; shoulder surgery; shoulder and elbow disease; arthroscopic surgery; orthopedic surgery

(This special issue belongs to the Section Orthopedics)

Kidney Transplantation: Challenges, Advances and Lessons Learnt

edited by

Karim Soliman

and

Tibor Fülöp

submission deadline 25 Jan 2026 | 1 articles | Viewed by 581 | Submission Open

Keywords: kidney transplantation; nephrology; transplant medicine; patient selection criteria; immunosuppressive treatment; long-term outcomes; graft survival; complication; multi-organ transplant consideration; innovation

(This special issue belongs to the Section Nephrology & Urology)

Machine Learning and Artificial Intelligence in Neurosurgery

edited by Jan Oliver Neumann and

Paul Naser

submission deadline 25 Jan 2026 | Viewed by 516 | Submission Open

Keywords: artificial intelligence; neurosurgery; neuro-oncology; spinal neurosurgery; neuro-ICU; stereotactic neurosurgery; pre-operative planning

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Hysteroscopic Technology for Gynecological Diseases

edited by Aya Mohr-Sasson and Raanan Meyer

submission deadline 25 Jan 2026 | Viewed by 334 | Submission Open

Keywords: diagnostic hysteroscopy; operative hysteroscopy; uterine sampling; uterine polyp; submucosal fibroid; hysteroscopic dilatation and curettage; hysteroscopic niche repair

(This special issue belongs to the Section Obstetrics & Gynecology)

Recent Clinical Advances in Reconstructive Urology and Prosthetic Surgery

edited by Elisa Berdondini and

Esaú Fenández-Pascual

submission deadline 25 Jan 2026 | Viewed by 169 | Submission Open

Keywords: reconstructive urology; penile prosthesis; artificial urinary sphincter; urethral stricture; reconstructive surgery; minimally invasive procedures

(This special issue belongs to the Section Nephrology & Urology)

Further Advances in Electrocardiography, Cardiac Arrhythmias, and Arrhythmogenic Disorders: 2nd Edition

edited by

Paweł T. Matusik

submission deadline 25 Jan 2026 | Viewed by 139 | Submission Open

Keywords: electrocardiography; cardiac arrhythmias; genetics; cardiac pacing; implantable cardioverter defibrillators; cardiac resynchronization therapy; magnetic resonance imaging; catheter ablation; arrhythmogenic disorders; channelopathy; cardiomyopathy

(This special issue belongs to the Section Cardiology)

Clinical Updates in the Use of Artificial Intelligence for Radiology

edited by

Martin R. Prince

submission deadline 25 Jan 2026 | Viewed by 137 | Submission Open

Keywords: deep learning; denoising; calculator; nn-UNet; automation; outcomes; quality control; DICE; Halsdorrf; Jaccard

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Otologic Disorders and Hearing Impairment: From Diagnosis to Rehabilitation

edited by Andrea Albera and Andrea Canale

submission deadline 25 Jan 2026 | Viewed by 110 | Submission Open

Keywords: otology; hearing loss; cochlear implants; middle ear surgery; otitis media; otosclerosis; auditory rehabilitation; ves-tibular disorders; hearing aid; bone-conduction implants

(This special issue belongs to the Section Otolaryngology)

Novel Developments on Diagnosis and Treatment of Atrial Fibrillation

edited by

Elena Bobescu

and Mihaela-Viviana Ivan

submission deadline 26 Jan 2026 | 5 articles | Viewed by 5454 | Submission Open

Keywords: atrial fibrillation; supraventricular arrhythmia; cardiovascular risk; oxidative stress; inflammation

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights into Peritoneal Dialysis and Hemodialysis: 2nd Edition

edited by

Grazia Maria Virzì

submission deadline 26 Jan 2026 | 2 articles | Viewed by 2758 | Submission Open

Keywords: hemodialysis; peritoneal dialysis; end-stage renal disease; kidney replacement therapy (KRT); pathophysiology; di-alysis membranes; dialysis preparation; dialysis modality; cardiovascular events; vascular access; PD-related perito-nitis; unfavorable adverse effects; complications; challenges; inflammation

(This special issue belongs to the Section Nephrology & Urology)

Osteoporotic Fractures of the Pelvis, Hip and Femur: Current Challenges and New Perspectives (2nd Edition)

edited by Andreas Hoch

submission deadline 26 Jan 2026 | Viewed by 107 | Submission Open

Keywords: osteoporosis; fracture management; pelvic fractures; periprosthetic fractures; proximal femoral fractures; non-operative therapies

(This special issue belongs to the Section Orthopedics)

Challenges in Diagnosis and Treatment of Infertility—2nd Edition

edited by Konstantinos A. Zikopoulos

submission deadline 27 Jan 2026 | 1 articles | Viewed by 5121 | Submission Open

Keywords: fertility; regeneration; age-related infertility; preimplantation diagnosis; precision assessment; individualized fertility needs; clinical diagnosis; in vitro fertilization

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Diagnosis and Treatment for Bone Tumor

edited by Antonio Ziranu and Luigi Cianni

submission deadline 27 Jan 2026 | 4 articles | Viewed by 4573 | Submission Open

Keywords: bone tumor; oncology; osteosarcoma; chondrosarcoma; megaprosthesis; bone resection; chemotherapy; radiotherapy; sarcoma; custom-made

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Scleral Lenses: New Insights in Lens Fitting and Customization

edited by

Daddi Fadel

and

Chelsea Bray

submission deadline 27 Jan 2026 | Viewed by 486 | Submission Open

Keywords: scleral lenses; scleral lens customization; higher-order aberrations; scleral lens optics; corneoscleral profilometry; keratoconus; ocular surface diseases; dry eye; wavefront-guided correction

(This special issue belongs to the Section Ophthalmology)

Heart Valve Surgery: Recent Trends and Future Perspective

edited by Per Nils J.F. Wierup, Johan Sjögren and Nina Hakacova

submission deadline 27 Jan 2026 | Viewed by 136 | Submission Open

Keywords: heart valve; diagnostics; surgery; echocardiography; computer simulation; prediction models

(This special issue belongs to the Section Cardiology)

Inflammatory Bowel Disease: Pathogenesis and Management Strategies

edited by

Jun Kato

submission deadline 28 Jan 2026 | 2 articles | Viewed by 1702 | Submission Open

Keywords: inflammatory bowel diseases; ulcerative colitis; Crohn’ s disease; biomarkers; risk factors; pharmacology; advanced therapy; endoscopic evaluation and procedures; extraintestinal manifestations; IBD-associated neoplasm

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Hepatitis: Prevention, Treatment, and Global Health Impact

edited by

Michał Brzdęk

,

Dorota Zarębska-Michaluk

and

Krystyna Dobrowolska

submission deadline 28 Jan 2026 | 1 articles | Viewed by 1022 | Submission Open

Keywords: hepatitis B; hepatitis C; liver disease; direct-acting antivirals (DAAs); global health; public health policy; viral hepa-titis elimination; health disparities; cirrhosis; vaccination programs

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Evidence and Future Directions in Clostridioides difficile Infection Epidemiology, Diagnosis and Treatment

edited by

Nicola Petrosillo

and

Guido Granata

submission deadline 28 Jan 2026 | Viewed by 143 | Submission Open

Keywords: Clostridioides difficile infection; infection control; contact isolation; community-acquired CDI; CDI recurrence; recurrence prevention; rCDI; host and microbiota interaction; antimicrobial treat-ment; microbiota transplant; underdiagnosis

(This special issue belongs to the Section Infectious Diseases)

Acute Myocardial Infarction: Clinical Advances in Prognostic Stratification, Diagnosis, and Treatment

edited by

Matteo Armillotta

,

Luca Bergamaschi

and

Carmine Pizzi

submission deadline 29 Jan 2026 | 5 articles | Viewed by 8589 | Submission Open

Keywords: acute myocardial infarction (AMI); atherosclerosis; ST segment elevation myocardial infarction (STEMI); non-ST elevation myocardial infarction (NSTEMI); acute coronary syndrome (ACS); prognosis; coronary CT angiography (CCTA); cardiac magnetic resonance (CMR); reperfusion therapy; antiplatelet therapy

(This special issue belongs to the Section Cardiology)

New Advances in Cardiorenal Syndrome: 2nd Edition

edited by

Rainer Ullrich Pliquett

submission deadline 30 Jan 2026 | 5 articles | Viewed by 17413 | Submission Open

Keywords: cardiorenal syndrome; outcome; hyperkalemia; acute kidney injury; chronic kidney disease; chronic heart failure

(This special issue belongs to the Section Cardiology)

Cerebral Palsy: Clinical Rehabilitation and Treatment

edited by Joav Merrick and

Dilipkumar R. Patel

submission deadline 30 Jan 2026 | 7 articles | Viewed by 16601 | Submission Open

Keywords: cerebral palsy; physiotherapy; occupational therapy; orthopedic management; medical management; rehabilitation approaches

(This special issue belongs to the Section Clinical Neurology)

Advances and Perspectives in Cancer Diagnostics and Treatment

edited by Alexandru E. Eniu,

Cristina Marinela Oprean

and

Simona Ruxandra Volovat

submission deadline 30 Jan 2026 | 7 articles | Viewed by 5907 | Submission Open

Keywords: solid tumors; new advances; diagnostics and treatment; clinical– pathological; genetic factors; AI; RWD; radiotherapy; biomarkers; prevention in cancer care; target therapy; immunotherapy

(This special issue belongs to the Section Oncology)

The Current Status and Future Directions of Pancreatoduodenectomy and Pancreatectomy

edited by

Vasileios K. Mavroeidis

,

Samir Pathak

and Somaiah Aroori

submission deadline 30 Jan 2026 | 2 articles | Viewed by 3199 | Submission Open

Keywords: pancreatic resection types; techniques and modifications; anastomotic techniques; open resection; minimally invasive surgery; laparoscopic resection; robotic resection; hybrid resection techniques; pancreatic resection post neoadjuvant treatment; lymphadenectomy; vascular resections; organ-sparing procedures; radicality; indications; complications

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates in Bleeding and Thrombotic Disorders

edited by

Hideo Wada

submission deadline 30 Jan 2026 | 2 articles | Viewed by 3117 | Submission Open

Keywords: autoimmune-acquired coagulation deficiency; acquired hemophilia A; disseminated intravascular coagulation; thrombotic microangiopathy; venous thromboembolism; acute coronary syndrome; clot waveform analysis; thrombin generation test; thromboelastogram

(This special issue belongs to the Section Hematology)

Current Advances in General and Regional Anesthesia

edited by Eleni Laou, Eleana Garini and Giolanda Varvarousi

submission deadline 30 Jan 2026 | 2 articles | Viewed by 2618 | Submission Open

Keywords: anesthesiology; general anesthesia; regional anesthesia; pediatric anesthesia; perioperative medicine; surgery; postoperative outcome; monitoring; analgesia; safety

(This special issue belongs to the Section Anesthesiology)

Advances in Minimally Invasive Surgery: Transformative Technologies, Techniques and Trends

edited by Michail Pitiakoudis

submission deadline 30 Jan 2026 | 2 articles | Viewed by 1838 | Submission Open

Keywords: minimally invasive surgery; laparoscopic surgery; robotic surgery; surgical innovation; hernia repair; colorectal surgery; gastrointestinal surgery; hepatopancreatobiliary surgery; surgical simulation; virtual reality; augmented reality; artificial intelligence; surgical training; patient outcomes; surgical oncology

(This special issue belongs to the Section General Surgery)

The Optimal Hybrid Revascularization Approach for Multilevel Peripheral Arterial Disease

edited by

Jin Hyun Joh

submission deadline 30 Jan 2026 | 1 articles | Viewed by 1441 | Submission Open

Keywords: peripheral arterial disease; revascularization; endovascular procedure; endarterectomy; limb salvage; patency; hybrid procedures; lower extremity; stents; angioplasty

(This special issue belongs to the Section Vascular Medicine)

Insights on Cancer Diagnosis, Treatment and Side Effects Management

edited by

Octav Ginghină

,

Mihai-Teodor Georgescu

and

Laurentia Nicoleta Gales

submission deadline 30 Jan 2026 | 1 articles | Viewed by 1348 | Submission Open

Keywords: cancer diagnosis; cancer treatment; side effects management; oncology; personalized medicine; supportive care

(This special issue belongs to the Section Oncology)

Clinical Outcomes in Bipolar and Depressive Disorders

edited by

Luca J. Steardo

and Francesco Monaco

submission deadline 30 Jan 2026 | 1 articles | Viewed by 835 | Submission Open

Keywords: mood disorders; clinical outcomes; treatment response; psychopathology; pathophysiology

(This special issue belongs to the Section Mental Health)

Mind–Body Connection: The Impact of Mental Health on Physical Well-Being

edited by

Mario Pinto

submission deadline 30 Jan 2026 | 1 articles | Viewed by 691 | Submission Open

Keywords: mind– body connection; mental health; well-being; metabolic balance; immune system; chronic medical conditions; body perception; self-image; eating disorders; psychosomatic disorders; psychosomatic medicine; innovative thera-peutic approaches; mindfulness; mind-wandering; integrated healthcare

(This special issue belongs to the Section Mental Health)

Atrial Fibrillation and Heart Failure: Diagnostic and Therapeutic Challenges and Breakthroughs

edited by

Silvius Alexandru Pescariu

,

Felix Bratosin

and

Cristian Mornos

submission deadline 30 Jan 2026 | Viewed by 194 | Submission Open

Keywords: atrial fibrillation; heart failure; cardiac electrophysiology; ventricular remodelling; rhythm control; catheter abla-tion; neurohormonal activation; biomarkers; ischemia; integrated cardiovascular care

(This special issue belongs to the Section Cardiology)

Colorectal Cancer: Early Detection, Treatment Advances and Patient Outcomes

edited by

Damiano Caputo

,

Roberto Cammarata

and Federica Giordano

submission deadline 30 Jan 2026 | Viewed by 180 | Submission Open

Keywords: colorectal cancer; early detection; prevention; innovation; screening; precision medicine; biomarkers; genetic profile

(This special issue belongs to the Section Oncology)

Causes and Advanced Treatments of Macular Edema

edited by

Gawęcki Maciej

and

Slawomir Teper

submission deadline 31 Jan 2026 | 4 articles | Viewed by 8162 | Submission Open

Keywords: macular edema; laser photocoagulation; subthreshold laser; anti-VEGF; optical coherence tomography; fluorescein angiography; angio-OCT

(This special issue belongs to the Section Ophthalmology)

The Role of Biomarkers in Cardiovascular Diseases

edited by Giorgia Panichella

submission deadline 31 Jan 2026 | 5 articles | Viewed by 6953 | Submission Open

Keywords: biomarkers; cardiovascular diseases; heart failure; ischemic heart disease; cardiomyopathy; risk stratification; diagnosis; prognosis; inflammation

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Management, Diagnosis and Treatment of Thoracic Diseases: 2nd Edition

edited by

Damiano D’Ardes

and

Andrea Boccatonda

submission deadline 31 Jan 2026 | 2 articles | Viewed by 5636 | Submission Open

Keywords: lung; thorax; pneumonia; chest; imaging; ultrasound

(This special issue belongs to the Section Respiratory Medicine)

Diagnosis and Treatment of Obstetrics and Gynecology Cancers

edited by

Gaspare Cucinella

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4777 | Submission Open

Keywords: gynecological cancers; endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; vaginal cancer; breast cancer; surgery; radio-therapy; systemic treatment; immunotherapy; sentinel lymph node biopsy; minimally invasive surgery; fertility preservation; gestational trophoblastic disease

(This special issue belongs to the Section Obstetrics & Gynecology)

Acute Coronary Syndromes: Clinical Advances in Diagnosis and Treatment

edited by Pierre Sabouret,

Giuseppe Andò

and

Elad Asher

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3959 | Submission Open

Keywords: acute coronary syndromes; myocardial infarction; cardiac biomarkers; antiplatelet therapy; revascularization; precision medicine; risk stratification

(This special issue belongs to the Section Cardiology)

Thoracic Surgery: Updates and New Trends

edited by

Monica Casiraghi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2637 | Submission Open

Keywords: minimally invasive surgery; new technology; diagnosis; bronchoscopy; robotic system; artificial intelligence

(This special issue belongs to the Section Respiratory Medicine)

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