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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Preventive, Diagnostic and Therapeutic Strategies for Abdominal Surgery Complications (Second Edition)

edited by

Orestis Ioannidis

submission deadline 25 May 2026 | 5 articles | Viewed by 9601 | Submission Open

Keywords: complications; diagnosis; treatment; management; morbidity; abdomen; abdominal surgery; outcome; postoperative

(This special issue belongs to the Section General Surgery)

Recent Progress in Rehabilitation Medicine—3rd Edition

edited by

Masahiro Kohzuki

submission deadline 25 May 2026 | 3 articles | Viewed by 8945 | Submission Open

Keywords: neuro-rehabilitation; cognitive rehabilitation; spinal rehabilitation; orthopedic rehabilitation; pediatric rehabilitation; cancer rehabilitation; visceral rehabilitation; cardiac rehabilitation; pulmonary rehabilitation; renal rehabilitation; hepatic rehabilitation; rehabilitation for transplantation; fitness; peak VO2; multimorbidity and multiple disabilities (MMD); adding life to years and years to life

(This special issue belongs to the Section Clinical Rehabilitation)

Oral and Maxillofacial Surgery: Diagnosis, Management and Future Opportunities

edited by

Federico Gelpi

submission deadline 25 May 2026 | 5 articles | Viewed by 8668 | Submission Open

Keywords: head and neck oncology; free flaps; oral surgery; malformative surgery; traumatology; endoscopy; preprosthetic surgery; reconstructive surgery; vascular malformations; osteonecrosis

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Diagnosis and Management of Vestibular Disorders

edited by

Sinisa Maslovara

, Mario Habek and

Andro Košec

submission deadline 25 May 2026 | 7 articles | Viewed by 8031 | Submission Open

Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management

(This special issue belongs to the Section Otolaryngology)

Clinical Utility of Optical Coherence Tomography in Ophthalmology: 2nd Edition

edited by

Jose Ignacio Fernandez-Vigo

submission deadline 25 May 2026 | 4 articles | Viewed by 7347 | Submission Open

Keywords: optical coherence tomography; ophthalmology; intraoperative OCT; en face OCT; wide-field OCT; retinal diseases; glaucoma; cornea; strabismus; cataract

(This special issue belongs to the Section Ophthalmology)

Future Opportunities in Thoracic Surgery: The Cutting Edge: 2nd Edition

edited by

Giulio Maurizi

submission deadline 25 May 2026 | 2 articles | Viewed by 5941 | Submission Open

Keywords: surgical resection; immunotherapy; target therapy; thoracic surgery; thoracic oncology; lung cancer

(This special issue belongs to the Section Respiratory Medicine)

Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition

edited by Nikos Nikolettos and

Angeliki Tiptiri-Kourpeti

submission deadline 25 May 2026 | 3 articles | Viewed by 4190 | Submission Open

Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Novel Insights into the Diagnosis and Management of Inflammatory Bowel Disease (IBD)

edited by

Alina Ioana Tantau

submission deadline 25 May 2026 | 4 articles | Viewed by 4124 | Submission Open

Keywords: inflammatory bowel disease; non-invasive biomarkers; abdominal ultrasonography; colonoscopy; biologic therapy; small molecules; mucosal healing; brain-gut axis; dysbiosis; colorectal dysplasia

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The Rebirth of Ventral Skull Base Surgery through Multiportal Approaches: Endonasal, Transorbital, Transmaxillary and Transoral Routes

edited by Matteo de Notaris and Francesco Corrivetti

submission deadline 25 May 2026 | 3 articles | Viewed by 2791 | Submission Open

Keywords: skull base surgery; neuroendoscopy; neuroanatomy; multiportal approaches; technical advancements

(This special issue belongs to the Section Clinical Neurology)

Clinical Highlights in Uveal Melanoma

edited by Tomasz Chorągiewicz and

Joanna Dolar-Szczasny

submission deadline 25 May 2026 | 1 articles | Viewed by 2349 | Submission Open

Keywords: choroidal melanoma; uveal melanoma; radiotherapy; enucleation; brachytherapy

(This special issue belongs to the Section Ophthalmology)

Clinical Advances of Breast Surgery and Reconstruction

edited by

Glenda Giorgia Caputo

and Emanuele Cigna

submission deadline 25 May 2026 | 1 articles | Viewed by 2170 | Submission Open

Keywords: breast reconstruction; autologous breast reconstruction; implant-based breast reconstruction; DIEP; LICAP; breast implant infection

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Interstitial Lung Disease Secondary to Autoimmune Disorders: Recent Advances and Novel Perspectives

edited by

Gaetano La Rocca

Gianluca Sambataro

and Francesco Ferro

submission deadline 25 May 2026 | 1 articles | Viewed by 2017 | Submission Open

Keywords: interstitial lung disease; lung involvement; connective tissue diseases; rheumatoid arthritis; systemic vasculitis; radiomics; lung ultrasound; biomarkers; pathogenetic immunological pathways; therapeutic targets

(This special issue belongs to the Section Respiratory Medicine)

Advances in the Clinical Management of Perioperative Anesthesia: 2nd Edition

edited by Alessia Mattei, Rita Cataldo and

Alessandro Strumia

submission deadline 25 May 2026 | 3 articles | Viewed by 1960 | Submission Open

Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit

(This special issue belongs to the Section Anesthesiology)

Current Clinical Advances in Urinary Incontinence

edited by Adolf Lukanovic, David Lukanović and Mija Blaganje

submission deadline 25 May 2026 | 2 articles | Viewed by 1728 | Submission Open

Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices

(This special issue belongs to the Section Nephrology & Urology)

Diabetic Foot: Emerging Prevention Strategies and Epidemiology

edited by

Vilma Urbančič-Rovan

submission deadline 25 May 2026 | 2 articles | Viewed by 1525 | Submission Open

Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry

(This special issue belongs to the Section Endocrinology & Metabolism)

Innovative Technologies and Approaches in Eye Disease Management and Refractive Surgery

edited by

Hidenaga Kobashi

submission deadline 25 May 2026 | 1 articles | Viewed by 1521 | Submission Open

Keywords: multifocal intraocular lenses; femtosecond lasers; artificial intelligence; imaging; eye surgery; refractive surgery

(This special issue belongs to the Section Ophthalmology)

Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss—2nd Edition

edited by David Saceda-Corralo

submission deadline 25 May 2026 | 2 articles | Viewed by 1382 | Submission Open

Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss; frontal fibrosing alopecia

(This special issue belongs to the Section Dermatology)

Clinical Updates in Reproductive Endocrinology: 2nd Edition

edited by Iwona Bojar and

Dorota Raczkiewicz

submission deadline 25 May 2026 | 2 articles | Viewed by 1277 | Submission Open

Keywords: reproductive endocrinology; endocrine diseases in pregnancy; infertility; endocrine diagnostics in infertility; long-term consequences of endocrine disorders; therapy for endocrine disorders

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Maxillofacial Surgery—Historical and Future Perspectives and Controversies

edited by

Kamil Nelke

Maciej Dobrzyński

and

Michał Gontarz

submission deadline 25 May 2026 | 1 articles | Viewed by 1246 | Submission Open

Keywords: oral oncology; facial skeleton; oral cavity; surgical approaches; head and neck; parotid tumors; jaw cysts and tumors; bone healing; patient-specific solutions; surgery planning; artificial intelligence; soft tissues; cancers and tumors of the oral cavity; microsurgery perspectives; open surgery; endoscopic surgery; trauma surgery; facial traumatology; bone and soft tissues healing after trauma; jaw deformities; orthognathic surgery today and tomorrow

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Approaches and Challenges in Oral Rehabilitation

edited by

Yoko Hasegawa

and Takayuki Kosaka

submission deadline 25 May 2026 | 1 articles | Viewed by 1184 | Submission Open

Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Insights in Paediatric Endocrinology

edited by

Marco Fiore

submission deadline 25 May 2026 | 1 articles | Viewed by 639 | Submission Open

Keywords: endocrinology; pediatrics; hormones; therapy and treatment; adolescents; newborns

(This special issue belongs to the Section Clinical Pediatrics)

Interstitial Lung Diseases: New Treatments Based on Treatable Traits

edited by Francesco Amati

submission deadline 25 May 2026 | 1 articles | Viewed by 638 | Submission Open

Keywords: interstitial lung diseases; progressive pulmonary fibrosis; phenotypes; endotypes; treatment; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Transcatheter Aortic Valve Implantation- Clinical Management and Future Challenges

edited by Mohamed Farag

submission deadline 25 May 2026 | 1 articles | Viewed by 552 | Submission Open

Keywords: transcatheter aortic valve implantation; TAVI; bicuspid aortic valve; small annulus; prosthesis– patient mismatch; coronary reaccess; valve-in-valve TAVI; leaflet modification

(This special issue belongs to the Section Cardiovascular Medicine)

Anemia: Clinical Updates in Diagnosis, Management, and Treatment

edited by

Joan-Lluis Vives-Corrons

submission deadline 25 May 2026 | 1 articles | Viewed by 526 | Submission Open

Keywords: anemia; diagnostic tools; hematology; artificial intelligence; targeted therapy; hereditary hemolytic anemia

(This special issue belongs to the Section Hematology)

Multiple Sclerosis and Demyelinating Disease: Clinical Treatment and Management

edited by Sotirios Giannopoulos

submission deadline 25 May 2026 | 1 articles | Viewed by 503 | Submission Open

Keywords: multiple sclerosis; demyelinating disease; comorbidities; disease modifying treatments; neuromuscular disorder; myasthenia gravis

(This special issue belongs to the Section Clinical Neurology)

New Advances in Congenital Heart Disease

edited by

Efrén Martínez-Quintana

submission deadline 25 May 2026 | 1 articles | Viewed by 455 | Submission Open

Keywords: congenital heart disease; pediatric cardiology; adult congenital heart disease; cardiac surgery; interventional cardiology; long-term outcomes; cardiac imaging

(This special issue belongs to the Section Cardiology)

Current Perspectives on the Clinical Management of Respiratory Diseases

edited by

Pradeesh Sivapalan

and

Alexandr Ceasovschih

submission deadline 25 May 2026 | 1 articles | Viewed by 366 | Submission Open

Keywords: COPD; acute exacerbations; biomarkers; clinical trials; bronchiectasis; respiratory infections

(This special issue belongs to the Section Respiratory Medicine)

Anesthesia and Perioperative Management of Organ Transplants

edited by

Uzung Yoon

and Ji-Hye Kwon

submission deadline 25 May 2026 | Viewed by 319 | Submission Open

Keywords: liver transplantation; coagulation; reperfusion syndrome; perioperative evaluation; coronary artery disease; CDC; DBD; living donor liver transplant; pulmonary evaluation; hepatorenal syndrome; portopulmonary hypertension

(This special issue belongs to the Section Anesthesiology)

Non-Small Cell Lung Cancer (NSCLC): Recent Advances in Clinical Diagnosis and Treatment

edited by

Cesare Guida

submission deadline 25 May 2026 | 1 articles | Viewed by 281 | Submission Open

Keywords: novel screening tool; cancer biomarkers; predictive marker of immunotherapy; targeted therapy; radiotherapy; non-small cell lung cancer

(This special issue belongs to the Section Oncology)

Advances in Ablation Therapy for Atrial Fibrillation: Innovations and Clinical Applications

edited by Ioanna Koniari

submission deadline 25 May 2026 | Viewed by 216 | Submission Open

Keywords: atrial fibrillation; ablation; PFA; PVI; non-thermal energy; mapping system

(This special issue belongs to the Section Cardiology)

High-Risk Neuroblastoma and Rhabdoid Tumors: New Clinical Insights and Challenges (Second Edition)

edited by

Rupert Handgretinger

and Johannes Hubertus Schulte

submission deadline 25 May 2026 | Viewed by 169 | Submission Open

Keywords: neuroblastoma; rhabdoid tumor; autologous stem cell transplantation; allogeneic stem cell transplantation immunotherapy; anti-GD2 antibody; targeted therapy; CAR T-cells

(This special issue belongs to the Section Oncology)

Surgical Innovation and Clinical Outcomes in Plastic and Reconstructive Surgery

edited by Pari Naz Mohanna and Ayush Kapila

submission deadline 25 May 2026 | Viewed by 96 | Submission Open

Keywords: plastic and reconstructive surgery; microsurgery; breast reconstruction; surgical innovation; novel flap techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Advances and Challenges in Vascular and Endovascular Medicine: 2nd Edition

edited by

Luca Bertoglio

submission deadline 25 May 2026 | Viewed by 88 | Submission Open

Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies

(This special issue belongs to the Section Vascular Medicine)

Advances in the Clinical Management of Diabetic Retinopathy

edited by

Takeshi Iwase

submission deadline 25 May 2026 | Viewed by 85 | Submission Open

Keywords: retinal imaging; clinical outcomes; optical coherence tomography (OCT); vitrectomy; blood flow

(This special issue belongs to the Section Ophthalmology)

Clinical Advances in Personalized Psychiatry

edited by

Rosaria Di Lorenzo

submission deadline 25 May 2026 | Viewed by 85 | Submission Open

Keywords: personalized psychiatry; biomarkers; predictive modeling; precision diagnosis; neuroimaging biomarkers; effective treatments

(This special issue belongs to the Section Mental Health)

Clinical Advances in the Management of Abdominal and Thoracoabdominal Aortic Aneurysms

edited by

Daniela Mazzaccaro

submission deadline 25 May 2026 | Viewed by 84 | Submission Open

Keywords: abdominal aneurysm; thoraco-abdominal; computed-tomography angiography; branched endograft; branched endovascular aortic repair; fenestrated endograft; open surgery; 3-D printing

(This special issue belongs to the Section Vascular Medicine)

An Update to Trends and Strategies in Vascular and Endovascular Surgery

edited by Karin Pfister and Fiona Rohlffs

submission deadline 25 May 2026 | Viewed by 84 | Submission Open

Keywords: vascular surgery; endovascular surgery; carotid endarterectomy; peripheral vascular diseases; vascular imaging; aortic diseases; aortic aneurysm; arteriovenous malformation; pelvic venous disorder; endovenous procedures; pal-liative therapy concept

(This special issue belongs to the Section Vascular Medicine)

Musculoskeletal Imaging and Intervention: 2nd Edition

edited by

Miguel Malo-Urriés

and

Jacobo Rodríguez-Sanz

submission deadline 25 May 2026 | Viewed by 81 | Submission Open

Keywords: ultrasound; invasive physiotherapy; minimally invasive surgical procedures; magnetic resonance; image analysis

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Diagnosis and Treatment of Demyelinating Diseases

edited by

Dimitrios Tzanetakos

and John S. Tzartos

submission deadline 25 May 2026 | Viewed by 80 | Submission Open

Keywords: demyelinating diseases of the CNS; demyelinating diseases of the PNS; multiple sclerosis; neuromyelitis optica spectrum disorder (NMOSD); myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD); clinical diagnosis; biomarkers; therapeutics

(This special issue belongs to the Section Clinical Neurology)

How Clinicians See the Use of AI in Psychiatry

edited by

Georgios Floros

submission deadline 25 May 2026 | Viewed by 79 | Submission Open

Keywords: artificial intelligence; psychiatry; patient care; psychotherapy

(This special issue belongs to the Section Mental Health)

Acute and Chronic Heart Failure: Clinical Updates and Perspectives—2nd Edition

edited by Luigi Cappannoli and Cristina Aurigemma

submission deadline 25 May 2026 | Viewed by 72 | Submission Open

Keywords: acute heart failure; chronic heart failure; devices; drug therapy; percutaneous ventricular assist devices; cardiogenic shock; arrhythmias; ischemic heart disease

(This special issue belongs to the Section Cardiovascular Medicine)

Epilepsy and Cerebrovascular Disorders

edited by

Leonardo Roever

submission deadline 25 May 2026 | Viewed by 64 | Submission Open

Keywords: epilepsy; cerebrovascular disorders; stroke; post-stroke epilepsy; neuroinflammation; neuroimaging; electroenceph-alography; biomarkers; antiepileptic treatment; translational neuroscience

(This special issue belongs to the Section Clinical Neurology)

Advances in Kidney Transplantation: 2nd Edition

edited by Pedro Ruiz-Esteban, Domingo Hernández and Veronica López

submission deadline 25 May 2026 | Viewed by 53 | Submission Open

Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Management of Urologic Diseases

edited by Francesco Pio Bizzarri and Calogero Casà

submission deadline 25 May 2026 | Viewed by 49 | Submission Open

Keywords: prostate cancer; bladder cancer; kidney cancer; uro-oncology; radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Advancements in Anterior Cruciate Ligament Injury: From Diagnosis to the Return-to-Sports: 2nd Edition

edited by Alexandre Hardy and Nicolas Bouguennec

submission deadline 28 May 2026 | 3 articles | Viewed by 2759 | Submission Open

Keywords: anterior cruciate ligament reconstruction (ACLR); timing of ACLR; ramp lesion; meniscal lesion; lateral extra-articular procedure

(This special issue belongs to the Section Sports Medicine)

Innovations in Thoracic Surgery and Disease Management: Integrating Genomics, Technology, and Multidisciplinary Care

edited by

Marco Scarci

and

Savvas Lampridis

submission deadline 28 May 2026 | 1 articles | Viewed by 362 | Submission Open

Keywords: thoracic surgery; thoracic disease; genomic medicine; artificial intelligence; advanced imaging; multidisciplinary care; minimally invasive surgery; robotic surgery; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Novel Treatments for Vestibular Migraine

edited by

Teru Kamogashira

submission deadline 28 May 2026 | Viewed by 283 | Submission Open

Keywords: neuromodulation therapy; sympathetic nerve stimulation; CGRP-targeted therapy; dietary interventions; elimination diets; ketogenic diet; low-glycemic index diet; nutritional supplements; pathophysiology of vestibular migraine; clinical adoption of VM therapies

(This special issue belongs to the Section Otolaryngology)

Cerebrovascular Disease: Symptoms, Diagnosis and Current Treatment—Second Edition

edited by Alba Scerrati and Giorgio Mantovani

submission deadline 28 May 2026 | Viewed by 90 | Submission Open

Keywords: ischemic stroke; cerebral aneurysms; cerebral vascular malformation; cerebral venous disease; cerebral venous thrombosis

(This special issue belongs to the Section Clinical Neurology)

Spine Surgery Innovations: Treatments and Technologies

edited by

Marco D. Burkhard

and Tomoyuki Asada

submission deadline 29 May 2026 | Viewed by 429 | Submission Open

Keywords: AI; robotics; navigation; muscle preservation; minimally invasive surgery; motion preservation; alignment targets; implant materials; bone growth factors; custom-made implants

(This special issue belongs to the Section Orthopedics)

Pediatric Hearing Loss: Advances in Early Detection, Intervention and Family-Centered Care

edited by

Daniel Holzinger

and

Johannes Hofer

submission deadline 30 May 2026 | Viewed by 65 | Submission Open

Keywords: pediatric hearing loss; early intervention; early identification of language and communication disorders; develop-mental language disorders; predictors of outcomes; newborn hearing screening; pediatric audiology

(This special issue belongs to the Section Otolaryngology)

Displaying special issue 1201-1250 on page 25 of 32.

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