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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood
edited by Kamila Chęcińska and
submission deadline 20 Sep 2026 | 5 articles | Viewed by 5181 | Submission Open
Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Advances in Systemic Lupus Erythematosus (SLE)
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 5114 | Submission Open
Keywords: systemic lupus erythematosus; autoantibodies and biomarkers; lupus nephritis; new and novel treatments; targeted treatment or precision medicine; quality of life
(This special issue belongs to the Section Immunology & Rheumatology)
Modern Gynecological Surgery: Clinical Updates and Perspectives
edited by , and Maya Sophie de Wilde
submission deadline 20 Sep 2026 | 4 articles | Viewed by 4820 | Submission Open
Keywords: gynecological diseases; gynecological surgery; surgical options; individual treatment; women’s health care
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Antithrombotic Therapy in Cardiovascular Medicine
edited by Daniele Giacoppo and Antonio Greco
submission deadline 20 Sep 2026 | 6 articles | Viewed by 4105 | Submission Open
Keywords: anticoagulant; antiplatelet; antithrombotic therapy; cardiovascular pharmacotherapy; coronary artery disease; in-flammation; lipid-lowering drugs; lipid metabolism; residual cardiovascular risk; thrombosis
(This special issue belongs to the Section Cardiovascular Medicine)
New Insights into the Management of Psoriasis and Immune-Mediated Dermatoses
edited by Federico Bardazzi and Riccardo Balestri
submission deadline 20 Sep 2026 | 6 articles | Viewed by 3797 | Submission Open
Keywords: psoriasis; immune-mediated inflammatory diseases; biologic therapy; small-molecule drugs; personalized treatment; real-world evidence; comorbidities; patient-centered care
(This special issue belongs to the Section Dermatology)
Liquid Biopsies in Oral Cancer: Advances and New Perspectives submission deadline 20 Sep 2026 | 1 articles | Viewed by 3636 | Submission Open
Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Innovations and Advances in Primary Care and Family Medicine
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 3550 | Submission Open
Keywords: primary care; family medicine; integrated care; chronic disease management; multimorbidity; mental health; digital health; artificial intelligence; population health management; implementation research; health services research; interdisciplinary collaboration; evidence-based practice
(This special issue belongs to the Section Epidemiology & Public Health)
Contemporary Oral and Maxillofacial Surgery: Expert Consensus and Best Practices
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 3463 | Submission Open
Keywords: facial trauma; TMJ disorders; implant and sinus surgery; sleep apnea; cosmetic and reconstructive surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Residual Risk in High-Risk Patients Undergoing Percutaneous Coronary Intervention submission deadline 20 Sep 2026 | 1 articles | Viewed by 3452 | Submission Open
Keywords: cardiology; precision medicine; residual risk; acute coronary syndrome; percutaneous coronary intervention; PCI
(This special issue belongs to the Section Cardiology)
Minimally Invasive and Endoscopic Neurosurgery
edited by , Vassilios Tsitouras and Stylianos Kapetanakis
submission deadline 20 Sep 2026 | 1 articles | Viewed by 3411 | Submission Open
Keywords: traumatic brain injury; neuro-oncology; hydrocephalus and cerebrospinal fluid disorders; neuroendoscopy; endo-scopic neurosurgery; skull base surgery; vascular neurosurgery; functional neurosurgery; pediatric neurosurgey; minimally invasive spine surgery; endoscopic spine surgery; spine endoscopy
(This special issue belongs to the Section Clinical Neurology)
Bladder Cancer: Diagnosis and Treatments
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 3344 | Submission Open
Keywords: bladder cancer; urothelial cancer; radical cystectomy; targeted therapy; immunotherapy; non-muscle -invasive; muscle-invasive; chemotherapy
(This special issue belongs to the Section Nephrology & Urology)
Postpartum Depression: What Happened to My Wife? submission deadline 20 Sep 2026 | 3 articles | Viewed by 3337 | Submission Open
Keywords: postpartum depression; clinical and health psychology; perinatal trauma; clinical and health psychology; mental health and quality of life
(This special issue belongs to the Section Mental Health)
Innovations in Emergency and Critical Care Medicine
edited by Yoshiaki Iwashita
submission deadline 20 Sep 2026 | 3 articles | Viewed by 3300 | Submission Open
Keywords: emergency; artificial intelligence; Tele-ICU; point of care; electrical impedance tomography
(This special issue belongs to the Section Intensive Care)
Clinical Management in Chronic Pain: Innovations, Integration, and Interventions
edited by Giuliano Lo Bianco, Silvia Natoli and Sean Li
submission deadline 20 Sep 2026 | 3 articles | Viewed by 3030 | Submission Open
Keywords: chronic pain; clinical management; interventional pain medicine; spinal cord stimulation; regenerative medicine; diagnostic strategies; pain semeiotics; multidisciplinary approaches; personalized medicine; pain assessment; neuromodulation; evidence-based pain therapy
(This special issue belongs to the Section Clinical Neurology)
Personalized Treatments for Patients with Acute Lung Injury
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 3028 | Submission Open
Keywords: personalized; acute lung injury; acute respiratory distress syndrome (ARDS); ventilator-induced lung injury (VILI); pharmacotherapy; fluid resuscitation; phenotypes; mesenchymal stem cells; nano-systems; exosomes; biomarkers; computational models
(This special issue belongs to the Section Respiratory Medicine)
Advancements and Challenges in Retina Surgery: Second Edition
edited by Joaquín Marticorena and
submission deadline 20 Sep 2026 | 1 articles | Viewed by 3027 | Submission Open
Keywords: retina; vitreoretinal diseases; vitreotomes; optical coherence tomography; vitreoretinal surgery
(This special issue belongs to the Section Ophthalmology)
Minimally Invasive Surgery: Challenges and Solutions in Clinical Practice
edited by and Alessia Fassari
submission deadline 20 Sep 2026 | 2 articles | Viewed by 2758 | Submission Open
Keywords: laparoscopic surgery; minimally invasive surgery; surgical challenges; clinical practice; surgical training; robotic-assisted surgery; artificial intelligence in surgery; laparoscopic instrumentation; intraoperative complications; surgical innovation; skill enhancement; surgical outcomes
(This special issue belongs to the Section General Surgery)
Bridging Bench, Bedside, and Beyond: Clinical and Translational Strategies for Pregnancy Complications submission deadline 20 Sep 2026 | 3 articles | Viewed by 2654 | Submission Open
Keywords: high-risk pregnancy; cardiovascular complications; cardiometabolic complications; gestational diabetes; pregnancy complications; preeclampsia; hypertension; vascular disorders; endothelial dysfunction; clinical prediction; antenatal diagnosis; personalized treatment
(This special issue belongs to the Section Obstetrics & Gynecology)
Polycystic Ovary Syndrome (PCOS): From Diagnosis to Personalized and Integrated Treatment
edited by Satu Kuokkanen
submission deadline 20 Sep 2026 | 1 articles | Viewed by 2637 | Submission Open
Keywords: PCOS; integrated treatment model; metabolic abnormalities; mental health; adverse obstetric outcomes
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Research and Insights in Endometriosis submission deadline 20 Sep 2026 | 2 articles | Viewed by 2636 | Submission Open
Keywords: endometriosis; pelvic pain; infertility; inflammation; minimal access surgery; laparoscopy; hysteroscopy; robotics
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Emerging Treatment Options in Atrial Fibrillation
edited by Hoang Nhat Pham and Amitoj Singh
submission deadline 20 Sep 2026 | 1 articles | Viewed by 2503 | Submission Open
Keywords: atrial fibrillation; AF ablation; lifestyle intervention; rhythm control; pulsed field ablation; antiarrhythmic drugs; direct oral anticoagulants
(This special issue belongs to the Section Cardiology)
Advances and Challenges in Colorectal Cancer
edited by Vignesh Narasimhan
submission deadline 20 Sep 2026 | 4 articles | Viewed by 2458 | Submission Open
Keywords: anal fistula; advancement flap; ‎ligation of intersphincteric tract; haemorrhoid surgery; pilonidal surgery
(This special issue belongs to the Section Oncology)
Up-to-Date Research on Nerve Ultrasound
edited by and Eman A. Tawfik
submission deadline 20 Sep 2026 | 1 articles | Viewed by 2455 | Submission Open
Keywords: peripheral nerve ultrasound; polyneuropathy; nerve trauma; plexus neuritis; nerve tumors; entrapment syndromes; ultrasound techniques; guidelines
(This special issue belongs to the Section Clinical Neurology)
Acute Ischemic Heart Disease: Risk Factors, Diagnosis, Management and Prognosis
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 2445 | Submission Open
Keywords: acute coronary syndromes; STEMI; cardiogenic shock; primary angioplasty; antiplatelet therapies; anticoagulation; stent thrombosis; mechanical support devices; acute heart failure
(This special issue belongs to the Section Cardiology)
Pediatric Otolaryngology: Clinical Advances and Challenges submission deadline 20 Sep 2026 | 2 articles | Viewed by 2403 | Submission Open
Keywords: pediatric dizziness; laryngomalacia; subglottic stenosis; pediatric airway obstruction; intracapsular tonsillectomy; PITA (Powered Intracapsular Tonsillectomy and Adenoidectomy); pediatric sleep-disordered breathing; pediatric olfactory disorders; congenital anosmia
(This special issue belongs to the Section Clinical Pediatrics)
Emerging Radiotherapy Technologies and Trends
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 2321 | Submission Open
Keywords: image-guided radiotherapy (IGRT); 4D radiotherapy; SBRT; radiomics; FLASH therapy; MR-guided radiotherapy
(This special issue belongs to the Section Oncology)
Alopecia, Atopic Dermatitis and Other Chronic Inflammatory Skin Diseases: Pathogenesis, Comorbidities, and Precision Management submission deadline 20 Sep 2026 | 4 articles | Viewed by 2294 | Submission Open
Keywords: alopecia; atopic dermatitis; chronic urticaria; prurigo nodularis; chronic pruritus; inflammatory skin diseases; biomarkers; biologics; JAK inhibitors; quality of life; precision medicine
(This special issue belongs to the Section Dermatology)
Neurological Injury After Cardiac Arrest: Mechanisms, Prognostication, and Emerging Therapies
edited by and Nikos Gorgoraptis
submission deadline 20 Sep 2026 | 2 articles | Viewed by 2232 | Submission Open
Keywords: cardiac arrest; hypoxic–ischaemic brain injury; neuroprognostication; neuroprotection; biomarkers; targeted tem-perature management; multimodal monitoring; neurorehabilitation
(This special issue belongs to the Section Emergency Medicine)
Clinical Research and Application of Artificial Intelligence and Deep Learning in Dentistry and Oral and Maxillofacial Surgery
edited by , and Lara Katharina Franziska Schorn
submission deadline 20 Sep 2026 | 4 articles | Viewed by 2102 | Submission Open
Keywords: artificial intelligence; deep learning; machine learning; oral and maxillofacial surgery; dentistry; medical imaging; clinical decision support
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Challenges and Approaches to Post-Traumatic Stress Disorder (PTSD)
edited by
submission deadline 20 Sep 2026 | 1 articles | Viewed by 2052 | Submission Open
Keywords: PTSD treatment; implementation; prevention; prevalence; risk factors
(This special issue belongs to the Section Mental Health)
Management of Dyslipidemias: Enhancing Lipid Modification to Reduce Cardiovascular Risk: 2nd Edition
edited by and Etienne Khoury
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1958 | Submission Open
Keywords: cardiovascular disease; dyslipidemia; lipoprotein remnant; emerging lipid-lowering therapies; rare and severe causes of atherogenic lipid disorders; cardiovascular risk-related biomarkers; drug safety and efficacy
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Diagnosis and Treatment of Uveitis
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 1785 | Submission Open
Keywords: uveitis; intraocular tumors; medical retina; pediatric retina
(This special issue belongs to the Section Ophthalmology)
Clinical Advances in Autism Management submission deadline 20 Sep 2026 | 1 articles | Viewed by 1747 | Submission Open
Keywords: autism spectrum disorder; diagnosis; child; adult; youth; early intervention; therapy; epidemiology; relatives; resources; limitations; problems; health; epidemiology; perspectives; organization
(This special issue belongs to the Section Mental Health)
Cardiometabolic Insights into Metabolic Dysfunction: From Mechanisms to Therapeutic Strategies
edited by Alessandro Andreis, and
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1710 | Submission Open
Keywords: cardiovascular complications; pharmacological; interventional strategies; cardiology; endocrinology; hepatology
(This special issue belongs to the Section Cardiology)
Current Clinical Research in Oral Maxillofacial Surgery
edited by , Marcin Kozakiewicz, Łukasz J. Krakowczyk and Tadeusz Morawiec
submission deadline 20 Sep 2026 | 3 articles | Viewed by 1680 | Submission Open
Keywords: oral and maxillofacial surgery; craniofacial surgery; orthognathic surgery; maxillofacial trauma; head and neck oncology; microsurgical reconstruction; temporomandibular joint (TMJ); virtual surgical planning (VSP); patient-specific implants (PSI); complications and outcomes
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Atrial Fibrillation: Screening, Management and Outcomes
edited by Ahmed AlTurki and Vidal Essebag
submission deadline 20 Sep 2026 | 2 articles | Viewed by 1635 | Submission Open
Keywords: atrial fibrillation; ablation; pulmonary vein isolation; atrial fibrillation screening; wearable devices; anti-arrhythmic drugs; cardiovascular outcomes; subclinical atrial fibrillation
(This special issue belongs to the Section Cardiology)
Rehabilitation in Musculoskeletal Disease
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 1630 | Submission Open
Keywords: musculoskeletal disease; stroke rehabilitation; physical therapy; rehabilitation; chronic pain; manual therapy; exercise intervention
(This special issue belongs to the Section Clinical Rehabilitation)
Digestive Disorders: Updates on Disease Monitoring, Prediction Models and Management submission deadline 20 Sep 2026 | 2 articles | Viewed by 1533 | Submission Open
Keywords: inflammatory bowel disease; metabolic dysfunction-associated fatty liver disease; liver disease; alcohol related liver disease; infection; Clostridioides difficile infection
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Pediatric Oral Health: Developmental, Functional, and Special Care Perspectives submission deadline 20 Sep 2026 | 1 articles | Viewed by 1510 | Submission Open
Keywords: pediatric oral health; early childhood oral health; malocclusion; oral habits; craniofacial growth and development; dental development defects; dental trauma in children; orofacial functions; oral–systemic health; preventive and community dentistry; early oral intervention
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Advances in Artificial Intelligence in Oral Cancer Research, Early Diagnosis, and Personalized Therapy
edited by Aminollah Khormali
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1389 | Submission Open
Keywords: artificial intelligence; precision oncology; digital pathology; deep learning; early cancer detection; predic-tive modeling; oral cancer diagnostics
(This special issue belongs to the Section Oncology)
Recent Progress and Future Perspectives in Orthodontics submission deadline 20 Sep 2026 | 2 articles | Viewed by 1331 | Submission Open
Keywords: skeletal anchorage; temporary anchorage devices; multidisciplinary orthodontic treatment; digital orthodontics; clear aligner therapy; 3D imaging and virtual treatment planning; airway-focused orthodontics
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Advances in Vitreoretinal Surgery: 2nd Edition
edited by
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1325 | Submission Open
Keywords: vitrectomy; retinal detachment; macular holes; pediatric vitreoretinal surgery; vitrectomy instrumentation; macular surgery; complex retinal detachments; vitreoretinal surgery
(This special issue belongs to the Section Ophthalmology)
Clinical Challenges and Future Directions of Interstitial Lung Disease
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 1295 | Submission Open
Keywords: interstitial lung disease; progressive pulmonary fibrosis; early detection; clinical diagnosis; multidisciplinary discussion; treatment; non-pharmacological therapy; end-of-life care; patient-centered management
(This special issue belongs to the Section Respiratory Medicine)
Vertigo and Dizziness in Children: Clinical Updates submission deadline 20 Sep 2026 | 1 articles | Viewed by 1266 | Submission Open
Keywords: vertigo; dizziness; children; vestibular disorders; otorhinolaryngology
(This special issue belongs to the Section Clinical Pediatrics)
Advances in Managing High-Risk Pregnancies: Innovations in Diagnosis, Prevention and Clinical Care
edited by , Vivien Dütemeyer and Jacques Jani
submission deadline 20 Sep 2026 | 2 articles | Viewed by 1231 | Submission Open
Keywords: high-risk pregnancy; maternal–fetal medicine; prenatal diagnosis; fetal growth restriction; preeclampsia; preterm birth; biomarkers; maternal comorbidities; clinical imaging; precision obstetrics
(This special issue belongs to the Section Obstetrics & Gynecology)
Updates in the Use of Pharmacogenetics in Clinical Practice
edited by Rocío Morón Romero and Xando Díaz-Villamarín
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1193 | Submission Open
Keywords: pharmacogenetics; personalized medicine; clinical implementation; drug response; pharmacogenomics; precision medicine; healthcare integration; decision support; clinical implications of genetic testing
(This special issue belongs to the Section Pharmacology)
Clinical Applications of Echocardiographic Techniques in Cardiovascular Diagnostics
edited by Gianpiero Italiano and
submission deadline 20 Sep 2026 | 2 articles | Viewed by 1149 | Submission Open
Keywords: echocardiography; cardiovascular diagnostics; 3D echocardiography; strain imaging; speckle-tracking echocardi-ography; valvular heart disease; heart failure; interventional echocardiography; stress echocardiography; car-dio-oncology; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Treatment and Clinical Management of Necrotizing Pancreatitis submission deadline 20 Sep 2026 | 2 articles | Viewed by 1132 | Submission Open
Keywords: necrotizing pancreatitis; infected necrosis; step-up approach; necrosectomy; minimally invasive surgery; artificial intelligence; lumen-apposing metal stent; pancreatic necrosis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Perinatal and Postnatal Mental Health: State of the Art
edited by Adriana Mihai
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1128 | Submission Open
Keywords: peripartum depression; post-partum depression; parental–infant well-being; early detection; perinatal mental health; postnatal mental health; psychotherapy interventions
(This special issue belongs to the Section Mental Health)
Emerging Trends in Atrial Fibrillation Management
edited by Guy Rozen
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1114 | Submission Open
Keywords: cardiology; atrial fibrillation; left atrial appendage occlusion; echocardiography; pulse field ablation
(This special issue belongs to the Section Cardiology)
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